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The map label for this gene is ackA

Identifier: 150009952

GI number: 150009952

Start: 4086919

End: 4088121

Strand: Direct

Name: ackA

Synonym: BDI_3370

Alternate gene names: 150009952

Gene position: 4086919-4088121 (Clockwise)

Preceding gene: 150009951

Following gene: 150009953

Centisome position: 84.94

GC content: 49.29

Gene sequence:

>1203_bases
ATGAAGATTCTAGTATTGAACTGCGGTAGTAGTTCTATCAAATATAAGTTATTCGATATGACCTCCGGTGAGGTTATGGC
TCAAGGCGGTATCGAGAAAATCGGTTTGCCGGGCGCGTTCTTGAAATTGACGGACAAGGATGGCAAGAAGGTGGTTATCG
AGAGAGAGATCCCCGGCCATCAAGAAGGCATCGAGTTTATCCTGAGCGTGTTGACCGACGCTACTTATGGCTGCATCAAG
GACTATAAGGAGATTGATGCCGTGGGCCATCGCGTGGTACATGGTGGCGAGGAGTTCGCTTCCAGTGTATTGATCAATCA
GGATGTAATCAATAAGGTAATCGAGTGCTCTGATTTGGCTCCGCTTCATAACCCGGCTAACTTGAAGGGTGTTCGGGCGA
TGGAGGCTTTGATCCCGGGTATTCCTCAAGTAGCGGTGTTTGATACGGCTTTCCATCAGACCATGCCGGATTATGCGTAT
ATGTATGGTTTGCCTTACGAGATGTACAAGAAATATGGCGTACGTCGTTATGGCTTCCACGGAACCAGTCATCGATATGT
ATCCCGTCGTGCTTGCGAGATCTTAGGTGTTCCTTATGAGGATCAGAAGATTATCACGGCTCACGTAGGTAACGGTGGTT
CTATCACCGCTATCAAGAATGGTAAGAGCGTGGATACTTCCATGGGCTTGACTCCGGTTGAGGGTCTGTTGATGGGTACT
CGTTGCGGCGACGTGGATGCGGGTGCTTTGTCTTTCATCATGGATAAGGAAGGCATGGATGGTGCCGGCCTTTCCGACTT
GATCAATAAGAGAAGTGGTGTTGCCGGTCTTTCCGGAATCTCTTCCGATATGCGTGAGATCGAGGCTGCCGTAGCTGCCG
GAAATCCGCGTGCGATCATGACCTTGAACGTATATAACTACCGCATCAAGAAATATATAGGCGCTTATGCCGCCGCTATG
GGTGGTTGTGATATCTTGGTTTGGACCGGTGGTGTCGGCGAGAACCAATGGGCGACCCGTCGTGCGGTTTGTGAGAACAT
GGAATACATGGGCATGAAGATCGATGTAGAGAAGAACGAGGGCATGCGTGGCGAGGAGATGGTAATCAGCACTCCGGACA
GTAAGGTGACTATCATCGTCGTTCCTACGGATGAGGAATTCATGATCGCTGCCGATACCTTGGAGATCTTAGATAAAAAA
TAA

Upstream 100 bases:

>100_bases
GCTCCGTAGACGATATTTATAAGATGGTAGCGATCGCTTGTAATCAATCCATCGGTTTGAAATCCGCAAAATAATATAAT
AATCCTAACGACTTAATAAT

Downstream 100 bases:

>100_bases
CCAGTAACGTTTCATATAATTTTAGCTAATCCTCGCAGCTTACAAAACACGGGGTTAGTGTTTAGATCGCCCCGACACCG
GTTGGGGCGATCTTTTTTAT

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLTDKDGKKVVIEREIPGHQEGIEFILSVLTDATYGCIK
DYKEIDAVGHRVVHGGEEFASSVLINQDVINKVIECSDLAPLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAY
MYGLPYEMYKKYGVRRYGFHGTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAIKNGKSVDTSMGLTPVEGLLMGT
RCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAGLSGISSDMREIEAAVAAGNPRAIMTLNVYNYRIKKYIGAYAAAM
GGCDILVWTGGVGENQWATRRAVCENMEYMGMKIDVEKNEGMRGEEMVISTPDSKVTIIVVPTDEEFMIAADTLEILDKK

Sequences:

>Translated_400_residues
MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLTDKDGKKVVIEREIPGHQEGIEFILSVLTDATYGCIK
DYKEIDAVGHRVVHGGEEFASSVLINQDVINKVIECSDLAPLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAY
MYGLPYEMYKKYGVRRYGFHGTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAIKNGKSVDTSMGLTPVEGLLMGT
RCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAGLSGISSDMREIEAAVAAGNPRAIMTLNVYNYRIKKYIGAYAAAM
GGCDILVWTGGVGENQWATRRAVCENMEYMGMKIDVEKNEGMRGEEMVISTPDSKVTIIVVPTDEEFMIAADTLEILDKK
>Mature_400_residues
MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLTDKDGKKVVIEREIPGHQEGIEFILSVLTDATYGCIK
DYKEIDAVGHRVVHGGEEFASSVLINQDVINKVIECSDLAPLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAY
MYGLPYEMYKKYGVRRYGFHGTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAIKNGKSVDTSMGLTPVEGLLMGT
RCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAGLSGISSDMREIEAAVAAGNPRAIMTLNVYNYRIKKYIGAYAAAM
GGCDILVWTGGVGENQWATRRAVCENMEYMGMKIDVEKNEGMRGEEMVISTPDSKVTIIVVPTDEEFMIAADTLEILDKK

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=397, Percent_Identity=43.0730478589421, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=42.6767676767677, Blast_Score=317, Evalue=1e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_PARD8 (A6LHA9)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304695.1
- ProteinModelPortal:   A6LHA9
- SMR:   A6LHA9
- STRING:   A6LHA9
- GeneID:   5308519
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_3370
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   SSDFRDV
- ProtClustDB:   PRK00180
- BioCyc:   PDIS435591:BDI_3370-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43452; Mature: 43452

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLTDKDGKKVVIEREIPGH
CEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCEEEEEECCCCH
QEGIEFILSVLTDATYGCIKDYKEIDAVGHRVVHGGEEFASSVLINQDVINKVIECSDLA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCC
PLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAYMYGLPYEMYKKYGVRRYGFH
CCCCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHCCCCHHEEECCCHHHHHHCCCEEECCC
GTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAIKNGKSVDTSMGLTPVEGLLMGT
CCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHEEEEC
RCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAGLSGISSDMREIEAAVAAGNPRAIM
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
TLNVYNYRIKKYIGAYAAAMGGCDILVWTGGVGENQWATRRAVCENMEYMGMKIDVEKNE
EEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHCCEEEEEECCC
GMRGEEMVISTPDSKVTIIVVPTDEEFMIAADTLEILDKK
CCCCCEEEEECCCCEEEEEEEECCCCEEEEECHHHHHCCC
>Mature Secondary Structure
MKILVLNCGSSSIKYKLFDMTSGEVMAQGGIEKIGLPGAFLKLTDKDGKKVVIEREIPGH
CEEEEEECCCCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCEEEEEECCCCH
QEGIEFILSVLTDATYGCIKDYKEIDAVGHRVVHGGEEFASSVLINQDVINKVIECSDLA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHCCCC
PLHNPANLKGVRAMEALIPGIPQVAVFDTAFHQTMPDYAYMYGLPYEMYKKYGVRRYGFH
CCCCCCCCCHHHHHHHHCCCCCCEEEEHHHHHHCCCCHHEEECCCHHHHHHCCCEEECCC
GTSHRYVSRRACEILGVPYEDQKIITAHVGNGGSITAIKNGKSVDTSMGLTPVEGLLMGT
CCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHEEEEC
RCGDVDAGALSFIMDKEGMDGAGLSDLINKRSGVAGLSGISSDMREIEAAVAAGNPRAIM
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
TLNVYNYRIKKYIGAYAAAMGGCDILVWTGGVGENQWATRRAVCENMEYMGMKIDVEKNE
EEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCHHHCCEEEEEECCC
GMRGEEMVISTPDSKVTIIVVPTDEEFMIAADTLEILDKK
CCCCCEEEEECCCCEEEEEEEECCCCEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA