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The map label for this gene is uvrA [H]

Identifier: 150009867

GI number: 150009867

Start: 3966081

End: 3968864

Strand: Direct

Name: uvrA [H]

Synonym: BDI_3283

Alternate gene names: 150009867

Gene position: 3966081-3968864 (Clockwise)

Preceding gene: 150009860

Following gene: 150009872

Centisome position: 82.43

GC content: 49.89

Gene sequence:

>2784_bases
ATGTCTGAGAGCAATTCGATTTTCATCAAGGGGGCACGTGTCAACAACTTGAAAAATATAGATGTAGAGATTCCGAGGGA
CAAGCTGGTGGTGATAACCGGGCTGTCGGGGAGTGGAAAATCATCGTTGGCGTTCGATACCCTTTATGCGGAGGGACAGC
GTCGGTATGTAGAGAGTTTATCCGCTTACGCCCGCCAGTTCTTGGGGAGGATGAGTAAGCCGGAATGCGACTATATTAAG
GGAATACCGCCGGCTATCGCTATCGAGCAGAAGGTGAATACCCGTAATCCGCGTTCCACGGTCGGTACATCTACCGAGAT
TTATGAGTATTTACGCTTGTTATATGCTCGCGTCGGGAAGACGATATCGCCGGTTTCCGGCACCGAGGTGAAAAAACATC
AGGTGAGCGATATTGTCAAGGAGGTCATGCGATACCCCGAGGGGACTCGTTTTGCCGTATTCGCCCCGGTTGTCTTGCCG
GAAGGCCGGGATATGAAGGAACAGCTGGAGATCTTGCGGAAAGAAGGATATGCCCGTCTGTCGGTGAATGATACGGTATA
TCGTATCTCGGAGGTACTGGCCAGCGAGGAGTTGCTGTCTTACCCGATCGAGTTGTTGGTGGACCGCCTGACGGTATCGG
ACGATAAGACCTTGAAAAGCCGTTTGGCGGATTCGGCCGAGACCGCTTTCTTTGAGGGCCATGGTACCTGTTTGATTCGT
ATTTATACGGAGGAAGGGGTAGTCGTGAAGGAATTCTCGAAGAAGTTTGAGGCGGATGGCATGATATTCGAGGAGCCTAC
CGATATGATGTTTAGCTTTAATAATCCGTTGGGCGCTTGTCCGACTTGTGAGGGGTTCGGTAAGGTGCTGGGCATCGATG
AGAATCTGGTGGTGCCCGATAAAAGTTTGTCTGTCTACCAAGGAGCCGTGGTTTGCTGGAAAGGTGAGGTGATGGGGGAA
TGGCTGAAAGACTTTATTGTGAAGAGCGAGAAATATAACTTCCCGATCCACCGCCCGTATTACGACCTGACACAGAAAGA
GAAGGATTTGTTGTGGCATGGGGCGAGAGGTTTACACGGCATCGACGATTTCTTTAAGTTCGTGGAAGAGAATCTTTATA
AGATACAATACCGGGTGATGCAAGCCCGCTATCGGGGAAAGACGACTTGCCCGGTTTGTAAGGGGAGCCGCTTGAGGCCG
GAAGCGCTGTATGTGCAAGTGGGCGGTAAGAATATCGCCGAGCTGGTGACGATGCCGGTTTCGGAGGCAAAGGCTTTCTT
TGATCAACTGGAACTGGACGAGACGGATGCGGCGATCGCTAAACGTTTGCTCACGGAAATCAATAATCGCTTGCAATTCC
TGTTGGATGTGGGGTTGGGTTATCTGGCTTTAGATCGCCTCTCGGCCTCTTTATCCGGAGGAGAGAGCCAACGTATCAAT
CTGGCTACCTCGTTGGGTAGTAGCTTGGTGGGTTCGTTGTATATTTTGGATGAGCCGAGTATCGGTCTGCATTCCCGGGA
TACGGATTTGTTGATCAAGGTATTGCGACAGTTGCAAGCCTTGGGGAATACCGTGGTCGTGGTGGAACATGATGAGGAGA
TTATCCGTGCGGCGGATTATATCATCGATATCGGTCCGAAAGCGGGGCGTTTGGGGGGTGAGGTCGTTTATCAAGGCGAT
GTGAATAACCTCCGGAAATGTAGCGATAGCCATACGGTACGTTATTTGACGGGAGAGGATCAGATCGAGATCCCGCCTTA
TCGGCGTCCGTGGAATAATTATATAGAAGTGACAGGGGCTCGGAAGAATAACTTAAAGGGTGTGGACGTGAAGTTTCCTT
TGAACGTGATGACGGTGGTTACCGGCGTGAGCGGTTCGGGTAAAAGTTCCTTGGTTCGTGATATTTTCTACGAGGGCGTG
AAACGCCATTTGGATGATGCCGCTCGCCTGACCGTAGATTGCTCCGGTATCAGTGGAGATTTGAATATGATTCAGGCGAT
TGAGTTTGTAGACCAGAACTCGATCGGAAAGAGTTCTCGCTCGAACCCTGTGACGTATATCGGCGCTTACGATGAGATCC
GTAAACTATTCGGTGAGCAGCCTCTTGCGAAGCAGATGGGATATAACGCCGCTTATTTTTCCTTTAATAAAGAAGGAGGT
CGCTGCGAGGAATGTAAGGGCGAGGGCAAAATCACGGTAGAGATGCAGTTTATGGCGGATATCACCTTGGAATGCGAGGC
TTGCCACGGCAAACGCTTCAAGCAGGATGTATTGGATGTAGAGTATCAAGGCGCTAACATATACGATGTGTTGGAAATGA
CCGTGAATCAAGCGATCGAGTTCTTCGAGAAAGGTTCCGGCTCCCAAGAGAAGAAGATCGTGAAACGCTTGAAACCGCTG
CAAGACGTAGGTTTGGGCTATATCAAGCTGGGACAGACTTCCTCCACTTTATCCGGTGGTGAGAACCAACGTGTGAAACT
GGCTTATTACTTAGGCCAAGAGAAGCAGCAACCTACCTTGTTCGTTTTCGACGAGCCTACGACCGGTTTACATTTTCATG
ATATCAAGACTTTGTTGAAAGCTTTCAATGCCTTGATCGAGAAAGGTCACTCCGTGGTAATTATCGAGCATAATATGGAT
GTGATCAAATGTGCGGATTATGTGATCGATTTAGGACCGGAAGGCGGAAAGGCCGGCGGGCAGTTGGTTTGTGCCGGCAC
ACCGGAGGAGATAGCGGCTTGCGAGGCATCCTATACCGGAAGGTTTTTAAGGGATAAGTTATAA

Upstream 100 bases:

>100_bases
GAGGCACACCCTGTCTAACTGTGTGAATTAGTTCGATGAAGATAGGGCAGAATCGGTTAGTTTTGGCTATCTTTGCGTTA
AAGAAAAAGATAAAGGTAAT

Downstream 100 bases:

>100_bases
GGAGACGATATAAAAAGACAAATGTAAATAGCTCCTGCCCGAATATTCGGATAGGAGCTATTTCTTTTAAGAGGAATGGG
AGCATTTCCATTAATATCCT

Product: excinuclease ABC subunit A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 927; Mature: 926

Protein sequence:

>927_residues
MSESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGRMSKPECDYIK
GIPPAIAIEQKVNTRNPRSTVGTSTEIYEYLRLLYARVGKTISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLP
EGRDMKEQLEILRKEGYARLSVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTLKSRLADSAETAFFEGHGTCLIR
IYTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNPLGACPTCEGFGKVLGIDENLVVPDKSLSVYQGAVVCWKGEVMGE
WLKDFIVKSEKYNFPIHRPYYDLTQKEKDLLWHGARGLHGIDDFFKFVEENLYKIQYRVMQARYRGKTTCPVCKGSRLRP
EALYVQVGGKNIAELVTMPVSEAKAFFDQLELDETDAAIAKRLLTEINNRLQFLLDVGLGYLALDRLSASLSGGESQRIN
LATSLGSSLVGSLYILDEPSIGLHSRDTDLLIKVLRQLQALGNTVVVVEHDEEIIRAADYIIDIGPKAGRLGGEVVYQGD
VNNLRKCSDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGARKNNLKGVDVKFPLNVMTVVTGVSGSGKSSLVRDIFYEGV
KRHLDDAARLTVDCSGISGDLNMIQAIEFVDQNSIGKSSRSNPVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGG
RCEECKGEGKITVEMQFMADITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIEFFEKGSGSQEKKIVKRLKPL
QDVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTLFVFDEPTTGLHFHDIKTLLKAFNALIEKGHSVVIIEHNMD
VIKCADYVIDLGPEGGKAGGQLVCAGTPEEIAACEASYTGRFLRDKL

Sequences:

>Translated_927_residues
MSESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGRMSKPECDYIK
GIPPAIAIEQKVNTRNPRSTVGTSTEIYEYLRLLYARVGKTISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLP
EGRDMKEQLEILRKEGYARLSVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTLKSRLADSAETAFFEGHGTCLIR
IYTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNPLGACPTCEGFGKVLGIDENLVVPDKSLSVYQGAVVCWKGEVMGE
WLKDFIVKSEKYNFPIHRPYYDLTQKEKDLLWHGARGLHGIDDFFKFVEENLYKIQYRVMQARYRGKTTCPVCKGSRLRP
EALYVQVGGKNIAELVTMPVSEAKAFFDQLELDETDAAIAKRLLTEINNRLQFLLDVGLGYLALDRLSASLSGGESQRIN
LATSLGSSLVGSLYILDEPSIGLHSRDTDLLIKVLRQLQALGNTVVVVEHDEEIIRAADYIIDIGPKAGRLGGEVVYQGD
VNNLRKCSDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGARKNNLKGVDVKFPLNVMTVVTGVSGSGKSSLVRDIFYEGV
KRHLDDAARLTVDCSGISGDLNMIQAIEFVDQNSIGKSSRSNPVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGG
RCEECKGEGKITVEMQFMADITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIEFFEKGSGSQEKKIVKRLKPL
QDVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTLFVFDEPTTGLHFHDIKTLLKAFNALIEKGHSVVIIEHNMD
VIKCADYVIDLGPEGGKAGGQLVCAGTPEEIAACEASYTGRFLRDKL
>Mature_926_residues
SESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGRMSKPECDYIKG
IPPAIAIEQKVNTRNPRSTVGTSTEIYEYLRLLYARVGKTISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLPE
GRDMKEQLEILRKEGYARLSVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTLKSRLADSAETAFFEGHGTCLIRI
YTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNPLGACPTCEGFGKVLGIDENLVVPDKSLSVYQGAVVCWKGEVMGEW
LKDFIVKSEKYNFPIHRPYYDLTQKEKDLLWHGARGLHGIDDFFKFVEENLYKIQYRVMQARYRGKTTCPVCKGSRLRPE
ALYVQVGGKNIAELVTMPVSEAKAFFDQLELDETDAAIAKRLLTEINNRLQFLLDVGLGYLALDRLSASLSGGESQRINL
ATSLGSSLVGSLYILDEPSIGLHSRDTDLLIKVLRQLQALGNTVVVVEHDEEIIRAADYIIDIGPKAGRLGGEVVYQGDV
NNLRKCSDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGARKNNLKGVDVKFPLNVMTVVTGVSGSGKSSLVRDIFYEGVK
RHLDDAARLTVDCSGISGDLNMIQAIEFVDQNSIGKSSRSNPVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGGR
CEECKGEGKITVEMQFMADITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIEFFEKGSGSQEKKIVKRLKPLQ
DVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTLFVFDEPTTGLHFHDIKTLLKAFNALIEKGHSVVIIEHNMDV
IKCADYVIDLGPEGGKAGGQLVCAGTPEEIAACEASYTGRFLRDKL

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=956, Percent_Identity=43.9330543933054, Blast_Score=759, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR003593
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 103338; Mature: 103207

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESL
CCCCCEEEEEECEECCCCCCEEECCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHH
SAYARQFLGRMSKPECDYIKGIPPAIAIEQKVNTRNPRSTVGTSTEIYEYLRLLYARVGK
HHHHHHHHHCCCCCCCCHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLPEGRDMKEQLEILRKEGYARL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCEEE
SVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTLKSRLADSAETAFFEGHGTCLIR
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCHHHEEEECCCEEEEE
IYTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNPLGACPTCEGFGKVLGIDENLVVPD
EEECCCEEHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCHHEECCCCCEECCC
KSLSVYQGAVVCWKGEVMGEWLKDFIVKSEKYNFPIHRPYYDLTQKEKDLLWHGARGLHG
CCCHHHCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCC
IDDFFKFVEENLYKIQYRVMQARYRGKTTCPVCKGSRLRPEALYVQVGGKNIAELVTMPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCH
SEAKAFFDQLELDETDAAIAKRLLTEINNRLQFLLDVGLGYLALDRLSASLSGGESQRIN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LATSLGSSLVGSLYILDEPSIGLHSRDTDLLIKVLRQLQALGNTVVVVEHDEEIIRAADY
HHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
IIDIGPKAGRLGGEVVYQGDVNNLRKCSDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGA
EEECCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEC
RKNNLKGVDVKFPLNVMTVVTGVSGSGKSSLVRDIFYEGVKRHLDDAARLTVDCSGISGD
CCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCC
LNMIQAIEFVDQNSIGKSSRSNPVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGG
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHHCCCCEEEEEECCCCC
RCEECKGEGKITVEMQFMADITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIE
CCHHCCCCCEEEEEEEEEECEEEEEECCCCCHHHHHHHCEEECCCCHHHHHHHHHHHHHH
FFEKGSGSQEKKIVKRLKPLQDVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTL
HHHCCCCCHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEE
FVFDEPTTGLHFHDIKTLLKAFNALIEKGHSVVIIEHNMDVIKCADYVIDLGPEGGKAGG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHEEECCCCCCCCC
QLVCAGTPEEIAACEASYTGRFLRDKL
EEEECCCCHHHHHHCCHHCCHHHHHCC
>Mature Secondary Structure 
SESNSIFIKGARVNNLKNIDVEIPRDKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESL
CCCCEEEEEECEECCCCCCEEECCCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHH
SAYARQFLGRMSKPECDYIKGIPPAIAIEQKVNTRNPRSTVGTSTEIYEYLRLLYARVGK
HHHHHHHHHCCCCCCCCHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
TISPVSGTEVKKHQVSDIVKEVMRYPEGTRFAVFAPVVLPEGRDMKEQLEILRKEGYARL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCEEE
SVNDTVYRISEVLASEELLSYPIELLVDRLTVSDDKTLKSRLADSAETAFFEGHGTCLIR
ECCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHCCCHHHEEEECCCEEEEE
IYTEEGVVVKEFSKKFEADGMIFEEPTDMMFSFNNPLGACPTCEGFGKVLGIDENLVVPD
EEECCCEEHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCHHEECCCCCEECCC
KSLSVYQGAVVCWKGEVMGEWLKDFIVKSEKYNFPIHRPYYDLTQKEKDLLWHGARGLHG
CCCHHHCCEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCC
IDDFFKFVEENLYKIQYRVMQARYRGKTTCPVCKGSRLRPEALYVQVGGKNIAELVTMPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCH
SEAKAFFDQLELDETDAAIAKRLLTEINNRLQFLLDVGLGYLALDRLSASLSGGESQRIN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LATSLGSSLVGSLYILDEPSIGLHSRDTDLLIKVLRQLQALGNTVVVVEHDEEIIRAADY
HHHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
IIDIGPKAGRLGGEVVYQGDVNNLRKCSDSHTVRYLTGEDQIEIPPYRRPWNNYIEVTGA
EEECCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEC
RKNNLKGVDVKFPLNVMTVVTGVSGSGKSSLVRDIFYEGVKRHLDDAARLTVDCSGISGD
CCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCC
LNMIQAIEFVDQNSIGKSSRSNPVTYIGAYDEIRKLFGEQPLAKQMGYNAAYFSFNKEGG
HHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHHCCCCEEEEEECCCCC
RCEECKGEGKITVEMQFMADITLECEACHGKRFKQDVLDVEYQGANIYDVLEMTVNQAIE
CCHHCCCCCEEEEEEEEEECEEEEEECCCCCHHHHHHHCEEECCCCHHHHHHHHHHHHHH
FFEKGSGSQEKKIVKRLKPLQDVGLGYIKLGQTSSTLSGGENQRVKLAYYLGQEKQQPTL
HHHCCCCCHHHHHHHHHCCHHHCCCCEEEECCCCCCCCCCCCCEEEEEEEECCCCCCCEE
FVFDEPTTGLHFHDIKTLLKAFNALIEKGHSVVIIEHNMDVIKCADYVIDLGPEGGKAGG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHEEECCCCCCCCC
QLVCAGTPEEIAACEASYTGRFLRDKL
EEEECCCCHHHHHHCCHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]