Click here to switch to the map view.

The map label for this gene is fklB [H]

Identifier: 150009786

GI number: 150009786

Start: 3875913

End: 3876431

Strand: Direct

Name: fklB [H]

Synonym: BDI_3202

Alternate gene names: 150009786

Gene position: 3875913-3876431 (Clockwise)

Preceding gene: 150009785

Following gene: 150009789

Centisome position: 80.56

GC content: 44.32

Gene sequence:

>519_bases
ATGAAGAAGTACTGGCATATTGCGTTGATGTTGTTTTGCGTGCTCATGATCACCTCTTGTGGGGATGATGATGAGGCACT
AGAGGTGGATGAGGTTTGGAAGGTCCAGAATGAGGAGGCTTTTCAAGCCCAGATGCTGGTTCCGGGTTTCGAGCAATTGA
GTTCTCAAAGTAATGCCGGATTTATCCTTTACAAGGTCTTGAAGACAGGAGAGAGTAAGGAGCCGATTTATTATACGAGC
AAGGTGGAATGTTATTATAAAGGGACGTTTATTGATGGAACGGTTTTTGATGATAAATCGTTTGAGGCAGGTGCCCCTGC
CGAGCTTACTGTTTCTGAGATGGTAGATGGTTTTGCTACAGCGTTACAGAATATGCACCCAGGAGATCGTTGGGAGATTT
GGATTCCTCAACAGATGGGATACGGTTCGGCTGGAAGGAGTGCTTCGGGAAGTGTCATAATAAAGCCTTATACGACTTTG
ATCTTTGATTTGGAAGTTACAAGGATTGTCAAAGAGTAG

Upstream 100 bases:

>100_bases
ACGATGGAGCAAGAGCGCGTAAGCATCGATAAGCTTCACGATATTATCACGGAGAAGGTGAGCATGAAGAATTTATTGAA
AAAGGTAATAGAGTAAACGA

Downstream 100 bases:

>100_bases
GTTCTTTCATTAAGAATAATTACGGCCGCCTCTTTTTAGGGGTGGCCGTTTTTTTATAGTTATATGTAAATCTAGGGAAG
CAAACCTCTATAAACAATTA

Product: putative FKBP-type peptidyl-prolyl cis-trans isomerase 1

Products: NA

Alternate protein names: FKBP22; PPIase; Rotamase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQMLVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTS
KVECYYKGTFIDGTVFDDKSFEAGAPAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTL
IFDLEVTRIVKE

Sequences:

>Translated_172_residues
MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQMLVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTS
KVECYYKGTFIDGTVFDDKSFEAGAPAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTL
IFDLEVTRIVKE
>Mature_172_residues
MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQMLVPGFEQLSSQSNAGFILYKVLKTGESKEPIYYTS
KVECYYKGTFIDGTVFDDKSFEAGAPAELTVSEMVDGFATALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTL
IFDLEVTRIVKE

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm. Periplasm. Note=According to PubMed:7610040 it is periplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI87082390, Length=107, Percent_Identity=40.1869158878505, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 19353; Mature: 19353

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQMLVPGFEQLSSQSNAG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHHEECCCCHHHHCCCCCCC
FILYKVLKTGESKEPIYYTSKVECYYKGTFIDGTVFDDKSFEAGAPAELTVSEMVDGFAT
EEEEEEECCCCCCCCEEEEEEEEEEEECEEECCEEECCCCCCCCCCCEEEHHHHHHHHHH
ALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFDLEVTRIVKE
HHHHCCCCCEEEEEECHHCCCCCCCCCCCCCEEEEEHEEEEEEHHHHHHHCC
>Mature Secondary Structure
MKKYWHIALMLFCVLMITSCGDDDEALEVDEVWKVQNEEAFQAQMLVPGFEQLSSQSNAG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCHHHHEECCCCHHHHCCCCCCC
FILYKVLKTGESKEPIYYTSKVECYYKGTFIDGTVFDDKSFEAGAPAELTVSEMVDGFAT
EEEEEEECCCCCCCCEEEEEEEEEEEECEEECCEEECCCCCCCCCCCEEEHHHHHHHHHH
ALQNMHPGDRWEIWIPQQMGYGSAGRSASGSVIIKPYTTLIFDLEVTRIVKE
HHHHCCCCCEEEEEECHHCCCCCCCCCCCCCEEEEEHEEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8703024; 9298646 [H]