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The map label for this gene is ptp [H]

Identifier: 150009665

GI number: 150009665

Start: 3694990

End: 3696279

Strand: Direct

Name: ptp [H]

Synonym: BDI_3080

Alternate gene names: 150009665

Gene position: 3694990-3696279 (Clockwise)

Preceding gene: 150009664

Following gene: 150009666

Centisome position: 76.8

GC content: 46.98

Gene sequence:

>1290_bases
ATGAGAAGAACATTTAACTTCTTGCTTCTTTTCTTCCTGTCGGTGATGACGGTAATGGCCGCTCCCGGAGATTTACAAGA
GAAGCTTGCCGCCCTAAAAGGAATTAGTGGCATTGAAAAACTTCAATCCGATTATTATCCGGAGAAATATGTAGTACGTA
TTACTCAGCAGGTCGATCCGAAAGACCCCGCCGCCGGAACATTTACGCAACGGGTTATCGTAGGCCATGTAGGTTATGAT
CGTCCTACCATTATCGTGACCGAAGGATATGGAGCGGCTTATGCGCTCAATCCGAAATATCAAGAAGAACTATCTAAACT
ATTGAATGCGAACTTAGTATTCGTGGAGTACCGTTATTTCTTGGAGTCGACGCCGGAACCTAAAAACTGGGATTATCTGA
CCGCCGAGAACTCTGCGTACGATTTACATAACGTCCGCAATACATTCAAGCAGATCTATCCGGGAAAATGGATCAGTACC
GGTATCAGTAAGGGGGGGCAGACTACAATGCTTTACCGTGCCTTTTTCCCGGACGACGTGGATTTCTCCGTTCCTTATGT
CGGTCCGTTATGTAAAGGTGTAGAGGATGGCCGCCACGAACCTTTCTTACGTAAGGTAGGTACGAAAGCGGAACGCGAGA
AGATACAGGATTTTCAATTGGAAGTCTTGAAGCGTAAGTCCGATATGCTTCCTTTATTGGAGAGCTATTGTAAGAATAAA
AACCTGACATTCCGTATCCCGATGCCCGAGGTATTGGATTATTGCGTACTGGAATATTCATTCGCTCTTTGGCAGTGGGG
AACTTCGGTAAGTACGATCCCTTCCAAGTCTGCCGACGATCAGGCGCTCTTCGATCATTTGATGGAAATCAGCGGTCCTG
ATTATTTCGCCGAGAACCAGCCGAATATCTCTTTCTTCGTACAAGCTGCCCGTGAGCTCGGTTATTATGGCTATGACGTA
AAACCTTTCAAGAAATACCTTACGATCGATAGCGCCCATGGATACCTAAACCGTATCATGCTTCCCGAGGAACTGGTCGG
TAAAGTAGACTTCCGTCCGGCTCTGTACCACAAGATCTATAACTTCTTGAAAGACAACGATCCGAAAATGATCTTCATCT
ATGGCGAGATCGACCCGTGGAGCGCGGCCATGGTTCCCGCTTTCAAAGGCAAGAAGAACGAGCAAATCTATATCCAGCCC
CGAGGCAGCCATCGTGCCCGTATCGGCAATATGCCGGAGGATATGAAGGAGCGGATCCTTACACAGATGAATAAATGGCT
GGCCGAGTAA

Upstream 100 bases:

>100_bases
CCGTGAGGATTATAATCGTATCTTTGCGCATTCGGCGGTGAAACGCGCCAAATATGAGGGATTATTACGAACAATACAAT
ATCTAAAAGACTAAATTACC

Downstream 100 bases:

>100_bases
AAATAGAGTAGCCTATTTTTTCCCTATAAAATCCCCGTATTATTACTTATCGGTTGTAATACGGGGATTTTGTCAGACTG
CTTCCTGATAACTTTGAATC

Product: putative secreted tripeptidyl aminopeptidase

Products: NA

Alternate protein names: PTP-SM; Tripeptidyl aminopeptidase; SM-TAP [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MRRTFNFLLLFFLSVMTVMAAPGDLQEKLAALKGISGIEKLQSDYYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYD
RPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYFLESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPGKWIST
GISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGVEDGRHEPFLRKVGTKAEREKIQDFQLEVLKRKSDMLPLLESYCKNK
NLTFRIPMPEVLDYCVLEYSFALWQWGTSVSTIPSKSADDQALFDHLMEISGPDYFAENQPNISFFVQAARELGYYGYDV
KPFKKYLTIDSAHGYLNRIMLPEELVGKVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKKNEQIYIQP
RGSHRARIGNMPEDMKERILTQMNKWLAE

Sequences:

>Translated_429_residues
MRRTFNFLLLFFLSVMTVMAAPGDLQEKLAALKGISGIEKLQSDYYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYD
RPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYFLESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPGKWIST
GISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGVEDGRHEPFLRKVGTKAEREKIQDFQLEVLKRKSDMLPLLESYCKNK
NLTFRIPMPEVLDYCVLEYSFALWQWGTSVSTIPSKSADDQALFDHLMEISGPDYFAENQPNISFFVQAARELGYYGYDV
KPFKKYLTIDSAHGYLNRIMLPEELVGKVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKKNEQIYIQP
RGSHRARIGNMPEDMKERILTQMNKWLAE
>Mature_429_residues
MRRTFNFLLLFFLSVMTVMAAPGDLQEKLAALKGISGIEKLQSDYYPEKYVVRITQQVDPKDPAAGTFTQRVIVGHVGYD
RPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYFLESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPGKWIST
GISKGGQTTMLYRAFFPDDVDFSVPYVGPLCKGVEDGRHEPFLRKVGTKAEREKIQDFQLEVLKRKSDMLPLLESYCKNK
NLTFRIPMPEVLDYCVLEYSFALWQWGTSVSTIPSKSADDQALFDHLMEISGPDYFAENQPNISFFVQAARELGYYGYDV
KPFKKYLTIDSAHGYLNRIMLPEELVGKVDFRPALYHKIYNFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKKNEQIYIQP
RGSHRARIGNMPEDMKERILTQMNKWLAE

Specific function: Has proline-specific tripeptidyl aminopeptidase and tetrapeptidyl aminopeptidase activity. Activity is highest against tripeptides containing an Ala-Pro motif. Involved in the final processing of transglutaminase, by removing either the tetrapeptide Phe-A

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted (PubMed:14519127). Cell surface (PubMed:15598885) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S37 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008761 [H]

Pfam domain/function: PF05576 Peptidase_S37 [H]

EC number: NA

Molecular weight: Translated: 49479; Mature: 49479

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTFNFLLLFFLSVMTVMAAPGDLQEKLAALKGISGIEKLQSDYYPEKYVVRITQQVDP
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHEEEEEHHCCC
KDPAAGTFTQRVIVGHVGYDRPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYF
CCCCCCHHHHHHEEEECCCCCCEEEEECCCCCEEEECCHHHHHHHHHHCCCEEEEEEEHH
LESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPGKWISTGISKGGQTTMLYRAFFPDDV
HCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCC
DFSVPYVGPLCKGVEDGRHEPFLRKVGTKAEREKIQDFQLEVLKRKSDMLPLLESYCKNK
CCCCCCCCHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
NLTFRIPMPEVLDYCVLEYSFALWQWGTSVSTIPSKSADDQALFDHLMEISGPDYFAENQ
CCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
PNISFFVQAARELGYYGYDVKPFKKYLTIDSAHGYLNRIMLPEELVGKVDFRPALYHKIY
CCHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCHHHHHCCCCHHHHCCCCCCHHHHHHHH
NFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKKNEQIYIQPRGSHRARIGNMPEDMKERIL
HHHHCCCCCEEEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
TQMNKWLAE
HHHHHHHCC
>Mature Secondary Structure
MRRTFNFLLLFFLSVMTVMAAPGDLQEKLAALKGISGIEKLQSDYYPEKYVVRITQQVDP
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCHHEEEEEHHCCC
KDPAAGTFTQRVIVGHVGYDRPTIIVTEGYGAAYALNPKYQEELSKLLNANLVFVEYRYF
CCCCCCHHHHHHEEEECCCCCCEEEEECCCCCEEEECCHHHHHHHHHHCCCEEEEEEEHH
LESTPEPKNWDYLTAENSAYDLHNVRNTFKQIYPGKWISTGISKGGQTTMLYRAFFPDDV
HCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEEECCCCC
DFSVPYVGPLCKGVEDGRHEPFLRKVGTKAEREKIQDFQLEVLKRKSDMLPLLESYCKNK
CCCCCCCCHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
NLTFRIPMPEVLDYCVLEYSFALWQWGTSVSTIPSKSADDQALFDHLMEISGPDYFAENQ
CCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
PNISFFVQAARELGYYGYDVKPFKKYLTIDSAHGYLNRIMLPEELVGKVDFRPALYHKIY
CCHHHHHHHHHHCCCCCCCCHHHHHHHEECCCCHHHHHCCCCHHHHCCCCCCHHHHHHHH
NFLKDNDPKMIFIYGEIDPWSAAMVPAFKGKKNEQIYIQPRGSHRARIGNMPEDMKERIL
HHHHCCCCCEEEEEECCCCCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHH
TQMNKWLAE
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA