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The map label for this gene is luxQ [H]

Identifier: 150009502

GI number: 150009502

Start: 3484001

End: 3486088

Strand: Direct

Name: luxQ [H]

Synonym: BDI_2915

Alternate gene names: 150009502

Gene position: 3484001-3486088 (Clockwise)

Preceding gene: 150009499

Following gene: 150009505

Centisome position: 72.41

GC content: 46.22

Gene sequence:

>2088_bases
ATGAAACGATATCTAATACATTTATGCTTATTATTTATGTCCTTTGTCGTTTCATCTCAAACGACTACACCAGACTCGCT
TAAAAGCGCCTTGCAAAAAACGACCTCCGAGCGCACAAGGCTGGAAATCCTCGCCAACTTGATGGATATCTCACGAAACG
ATGACATATTAGTAAACGCTAAACAACTCTATCAGGAAGCCTTAAAAGCGAATGACAATTACTATAAGGAAGCGGCATTG
ACCGAGATTCTCCGGCATTATATCAACACGGACCAAACCGATAGCGCAAATGTCTATATCGCCAAAGCCGAGCAGGAGCT
AAAAGGAGAAGCCAGAACCAGCCTCGTATCGTTCATGAAAATGATCCAAGATACGCGCGTCATATTCTACACATCCGGTG
AACCAAGAAGGAAAGTCCTCATGAATTGCCTATTCAAGCTGGAGGAACCCGACAAATTGTCTCCCTATGAGAAAATAGCC
TGCAATTATGTACTTGGTATGGCTGTCAGCAACAGCGTCATGGAGGAGAACATGCTTAAGGAGGACTTCAAGCAAGGGAA
AGAATATTTCGACAACGTCTTGACCGAGGCTGAAAAACTGCCCCTACGATACGCATACAATTTCTTGCCTAACACCTATT
TCATGCTATGCGCCTACGCTGCCGACCCTTGGGAGAGAGGGAAATACGCAACCCGCTATCTCAATACGATCTTAGGATAC
TCCAATATCCCGGAGATGAGCAAACGTCCTTACGCGACTAACAAGCGCCACTTGCTAAGCGCCTACTCCAACCTCGCCAT
CAGCGCCGAGGCTATCGGGAAGGATTTGGCCACTTCTTATTTCCATGAGTTCCAAAAGTTATTGAAGGCTTATCCGGAGG
CGGCTAGCACCACCCCGGAATACGAGCTATACTATACTTCCGCCAATTATTACCTAAACATCAAGGACTACATGAAATTC
ATTGAGTTCAGCGACTCCTTGATCAATTTCTCCAAACAAATACCGCTTTACAAGGAGCATGTAATCGCCTATGTATCCGC
AAAAGCCGCCGCCTACGACAGCCTCCGGATGTACAAGGAGGCCTATGAGACATCCAAAGAGTATGCGGTATTGCTAGATA
CCTTGCGTATGCAAGAACTCCGGAAGAAAATGGAAAATCTCGAGATCGAGAAAGGGGCGAACGAGTTGGTGATCGAAAAG
AGATCATTGGAATTGGAATTGCAGAAAAGCAAGAAGGAGAATTACCTATATATATCCCTATTGCTTCTAGCCTTATGCGC
CGTGTTCTATATCTTTTTCCGGCTAGGCAAAATGAGATCCCTCTATCGGGCATTGCAGAAGTCTAACGAGCTGGTCTTGA
TAGCGAACCAGAAAGCACAAGAGAGCGAGGAGATGAAGACCGCCTTCATCCGGAATATGTCGCATGAGATACGGACTCCC
TTAAACGCGATCAACGGTTTCTCGGAACTCATCACCAACGACGATATCTCCATGGACGAGAAACAGGCTTTCAGCCGTAT
TATCTATGAAAACTGTTACCATTTGACTTCCATGCTGAACAATCTCCTTGAGATCGCCCAGCTCGATAGCGGCAATGATT
CCCTTCCTCTTGTTCCCACACGTATCCATGAGCTTTGTATACATGAGATGCAACAGGTAAAGAAATATCAAGAGAAGCCG
GAGATCAACTATGTGGTGGAAGGCGATAAGGAGAATGATATGGTCTTGACCAACCGTGCTTATTTCAGTTTGATCATCTC
GCATCTGCTGGCAAACGCGAATAAATTCACGGAGAAAGGAAGCATCACGCTTTCATACCATCTGGATAGCGGAGCCAATT
TAGTGACCCTGTCGGTAACAGATACGGGTTGCGGCATCCCTCAAGACAAGCAGGAATGGATATTCGAGCGTTTCACGAAG
ACCAATGATTTCATTCCCGGCTCTGGCCTGGGGCTTTACCTATGTCGCTTGATCGTTAACCGGCTAAACGGTAAGATAAA
GACAGATCCGTCTTATACGAAAGGCTCACGCTTCGTTATCACGATGCCAATCGCCACGCCGTCCAAGCCCTCCGAACCTA
CCGATTAA

Upstream 100 bases:

>100_bases
TCAATTGTTTGTTTTTCTAACTATTTAATAGCTTTTTTATGGTGAGATTACGTATATTTGCATTTGTAATACAATAAACA
CAACAAGAGATTCTATTTGT

Downstream 100 bases:

>100_bases
CGAAAGAAACGTCCTACGTACGGGAGTTCTCGTAAAGGTAAATCCCTTTTAACCATAAACGCGATGAATACGCCTAATAA
GATTGTACGGTATCCCAACC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MKRYLIHLCLLFMSFVVSSQTTTPDSLKSALQKTTSERTRLEILANLMDISRNDDILVNAKQLYQEALKANDNYYKEAAL
TEILRHYINTDQTDSANVYIAKAEQELKGEARTSLVSFMKMIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIA
CNYVLGMAVSNSVMEENMLKEDFKQGKEYFDNVLTEAEKLPLRYAYNFLPNTYFMLCAYAADPWERGKYATRYLNTILGY
SNIPEMSKRPYATNKRHLLSAYSNLAISAEAIGKDLATSYFHEFQKLLKAYPEAASTTPEYELYYTSANYYLNIKDYMKF
IEFSDSLINFSKQIPLYKEHVIAYVSAKAAAYDSLRMYKEAYETSKEYAVLLDTLRMQELRKKMENLEIEKGANELVIEK
RSLELELQKSKKENYLYISLLLLALCAVFYIFFRLGKMRSLYRALQKSNELVLIANQKAQESEEMKTAFIRNMSHEIRTP
LNAINGFSELITNDDISMDEKQAFSRIIYENCYHLTSMLNNLLEIAQLDSGNDSLPLVPTRIHELCIHEMQQVKKYQEKP
EINYVVEGDKENDMVLTNRAYFSLIISHLLANANKFTEKGSITLSYHLDSGANLVTLSVTDTGCGIPQDKQEWIFERFTK
TNDFIPGSGLGLYLCRLIVNRLNGKIKTDPSYTKGSRFVITMPIATPSKPSEPTD

Sequences:

>Translated_695_residues
MKRYLIHLCLLFMSFVVSSQTTTPDSLKSALQKTTSERTRLEILANLMDISRNDDILVNAKQLYQEALKANDNYYKEAAL
TEILRHYINTDQTDSANVYIAKAEQELKGEARTSLVSFMKMIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIA
CNYVLGMAVSNSVMEENMLKEDFKQGKEYFDNVLTEAEKLPLRYAYNFLPNTYFMLCAYAADPWERGKYATRYLNTILGY
SNIPEMSKRPYATNKRHLLSAYSNLAISAEAIGKDLATSYFHEFQKLLKAYPEAASTTPEYELYYTSANYYLNIKDYMKF
IEFSDSLINFSKQIPLYKEHVIAYVSAKAAAYDSLRMYKEAYETSKEYAVLLDTLRMQELRKKMENLEIEKGANELVIEK
RSLELELQKSKKENYLYISLLLLALCAVFYIFFRLGKMRSLYRALQKSNELVLIANQKAQESEEMKTAFIRNMSHEIRTP
LNAINGFSELITNDDISMDEKQAFSRIIYENCYHLTSMLNNLLEIAQLDSGNDSLPLVPTRIHELCIHEMQQVKKYQEKP
EINYVVEGDKENDMVLTNRAYFSLIISHLLANANKFTEKGSITLSYHLDSGANLVTLSVTDTGCGIPQDKQEWIFERFTK
TNDFIPGSGLGLYLCRLIVNRLNGKIKTDPSYTKGSRFVITMPIATPSKPSEPTD
>Mature_695_residues
MKRYLIHLCLLFMSFVVSSQTTTPDSLKSALQKTTSERTRLEILANLMDISRNDDILVNAKQLYQEALKANDNYYKEAAL
TEILRHYINTDQTDSANVYIAKAEQELKGEARTSLVSFMKMIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIA
CNYVLGMAVSNSVMEENMLKEDFKQGKEYFDNVLTEAEKLPLRYAYNFLPNTYFMLCAYAADPWERGKYATRYLNTILGY
SNIPEMSKRPYATNKRHLLSAYSNLAISAEAIGKDLATSYFHEFQKLLKAYPEAASTTPEYELYYTSANYYLNIKDYMKF
IEFSDSLINFSKQIPLYKEHVIAYVSAKAAAYDSLRMYKEAYETSKEYAVLLDTLRMQELRKKMENLEIEKGANELVIEK
RSLELELQKSKKENYLYISLLLLALCAVFYIFFRLGKMRSLYRALQKSNELVLIANQKAQESEEMKTAFIRNMSHEIRTP
LNAINGFSELITNDDISMDEKQAFSRIIYENCYHLTSMLNNLLEIAQLDSGNDSLPLVPTRIHELCIHEMQQVKKYQEKP
EINYVVEGDKENDMVLTNRAYFSLIISHLLANANKFTEKGSITLSYHLDSGANLVTLSVTDTGCGIPQDKQEWIFERFTK
TNDFIPGSGLGLYLCRLIVNRLNGKIKTDPSYTKGSRFVITMPIATPSKPSEPTD

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=26.9961977186312, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=28.75, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=26.3374485596708, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=29.7413793103448, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=26.9387755102041, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=24.2914979757085, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790436, Length=283, Percent_Identity=24.7349823321555, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=25.3968253968254, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.9559471365639, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=26.3598326359833, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788549, Length=339, Percent_Identity=22.1238938053097, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=23.6947791164659, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80081; Mature: 80081

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYLIHLCLLFMSFVVSSQTTTPDSLKSALQKTTSERTRLEILANLMDISRNDDILVNA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
KQLYQEALKANDNYYKEAALTEILRHYINTDQTDSANVYIAKAEQELKGEARTSLVSFMK
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
MIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIACNYVLGMAVSNSVMEENMLK
HHHCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDFKQGKEYFDNVLTEAEKLPLRYAYNFLPNTYFMLCAYAADPWERGKYATRYLNTILGY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHCC
SNIPEMSKRPYATNKRHLLSAYSNLAISAEAIGKDLATSYFHEFQKLLKAYPEAASTTPE
CCCCCCCCCCCCCCHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YELYYTSANYYLNIKDYMKFIEFSDSLINFSKQIPLYKEHVIAYVSAKAAAYDSLRMYKE
EEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYETSKEYAVLLDTLRMQELRKKMENLEIEKGANELVIEKRSLELELQKSKKENYLYISL
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHCCCCCEEHHHH
LLLALCAVFYIFFRLGKMRSLYRALQKSNELVLIANQKAQESEEMKTAFIRNMSHEIRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCH
LNAINGFSELITNDDISMDEKQAFSRIIYENCYHLTSMLNNLLEIAQLDSGNDSLPLVPT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RIHELCIHEMQQVKKYQEKPEINYVVEGDKENDMVLTNRAYFSLIISHLLANANKFTEKG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHCCCC
SITLSYHLDSGANLVTLSVTDTGCGIPQDKQEWIFERFTKTNDFIPGSGLGLYLCRLIVN
CEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RLNGKIKTDPSYTKGSRFVITMPIATPSKPSEPTD
HHCCCEECCCCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKRYLIHLCLLFMSFVVSSQTTTPDSLKSALQKTTSERTRLEILANLMDISRNDDILVNA
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
KQLYQEALKANDNYYKEAALTEILRHYINTDQTDSANVYIAKAEQELKGEARTSLVSFMK
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
MIQDTRVIFYTSGEPRRKVLMNCLFKLEEPDKLSPYEKIACNYVLGMAVSNSVMEENMLK
HHHCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDFKQGKEYFDNVLTEAEKLPLRYAYNFLPNTYFMLCAYAADPWERGKYATRYLNTILGY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHCCHHHHHHHHHHHCC
SNIPEMSKRPYATNKRHLLSAYSNLAISAEAIGKDLATSYFHEFQKLLKAYPEAASTTPE
CCCCCCCCCCCCCCHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
YELYYTSANYYLNIKDYMKFIEFSDSLINFSKQIPLYKEHVIAYVSAKAAAYDSLRMYKE
EEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AYETSKEYAVLLDTLRMQELRKKMENLEIEKGANELVIEKRSLELELQKSKKENYLYISL
HHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCEEEECCCHHHHHHHCCCCCEEHHHH
LLLALCAVFYIFFRLGKMRSLYRALQKSNELVLIANQKAQESEEMKTAFIRNMSHEIRTP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCH
LNAINGFSELITNDDISMDEKQAFSRIIYENCYHLTSMLNNLLEIAQLDSGNDSLPLVPT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RIHELCIHEMQQVKKYQEKPEINYVVEGDKENDMVLTNRAYFSLIISHLLANANKFTEKG
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCHHHCCCC
SITLSYHLDSGANLVTLSVTDTGCGIPQDKQEWIFERFTKTNDFIPGSGLGLYLCRLIVN
CEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
RLNGKIKTDPSYTKGSRFVITMPIATPSKPSEPTD
HHCCCEECCCCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]