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The map label for this gene is pqqL [C]

Identifier: 150009484

GI number: 150009484

Start: 3458388

End: 3459608

Strand: Reverse

Name: pqqL [C]

Synonym: BDI_2897

Alternate gene names: 150009484

Gene position: 3459608-3458388 (Counterclockwise)

Preceding gene: 150009490

Following gene: 150009481

Centisome position: 71.9

GC content: 48.4

Gene sequence:

>1221_bases
ATGGATTATATCGCTCATACATTGCCGAATGGACTTCGCATGGTACATCTCCCGGTTAATTCCCCGGTTTCTTACTGCGG
TTTCGCCGTGAACGCCGGTACACGGGATGAGAACGAGGATGAATTTGGCTTGGCGCATTTCGTTGAACACATGATCTTCA
AAGGTACGGAGAAACGGAAAGCGTGGCATATCCTGAATCGTATGGAGAACGTAGGAGGGGAGTTGAATGCCTATACTACG
AAGGAAGAGACCTTTGTTTATTCCATTTTTATGGAGGAGGATTTTGGCCGGGCGTTTGAGCTATTGACCGATCTGGTTTT
CCATTCCCAATTCCCCAAACAGGAGATCGAGAAGGAGGTAGATGTCATCTTGGATGAGATCAATTCGTATGAGGATAGTC
CTTCGGAACTTATATTCGACGAGTTTGAGAACTTGCTTTATAAGGGTCATGCCCTCGGGCATAATATCTTAGGGGATGAG
GGATCTCTTCTTCGCTTTGACTCCGAGTCCGGTCGTTCTTTCATGCGTCGTTTCTACGCCCCGGAGAATATGGTGTTCTT
CTCGATGGGACGAAAAGACTTCAAGAATATCTTGAAATCAGCGGAATCCGCTTTAAGCGATATCTCTTTCCCGATGGCTG
AACGGATCCGGAAAGCTCCGGACCCCATCGAGGCTTGCGTACGCCAGATCCATAAAGATACCCATCAAGCCCATGTACTG
ATCGGTGGCCGGGCTTTCAGTATGCACGACAAAAAACGTATCCCTTTGTTCTTGTTGAACAATATCTTAGGTGGTCCGGG
CATGAATAACCGCTTGAATGTCTCCTTGCGGGAAAAGCATGGCTTGGTCTATAACGTAGAATCCAATATAACCTCTTATA
CCGATACCGGACTAGCCAGTATCTATTTCGGGACAGACCCGAAGAACCGTGAGAAAGCGATGCGTTTGGTGCATAAGGAA
TTGGCCCGTTTACGTGACGTAAAGCTGTCCGCCACTCAATTAGCCGCCGCCAAGAAGCAGGTAATCGGTCAACTGGGCGT
GTCGGGCGATAACCGGGAGGGTCTTTTCCTTGGCTTAGGAAAAAGCTACCTCCATTACAACCGTTACGACACCCTCCCTG
AAGTATTCGCCCAGATCGAGAAAATAACCGCCGGGCAAATCCTAGACGTGGCGAATGAGGTGTTCGCTCCGGAACGGTTG
TTTTGCTTGATTTATGAGTGA

Upstream 100 bases:

>100_bases
GTCTTTTTCCGGAAACACGTACATGTTTTTTGAAAAAGACGTACATGTTTTTCCGGAAAGTCTTTCGTACCTTTGCGGGC
TGATACAAACAAGAAGGAAA

Downstream 100 bases:

>100_bases
GGCTAATTATGGAACCTATACCCAACCCCCAACATCAAGTTATTCGGATTATGAAATTTGTGCAGTTGGTATCCGACATG
CAGGAATAAATTTCGTGTAA

Product: putative zinc protease YmxG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGLAHFVEHMIFKGTEKRKAWHILNRMENVGGELNAYTT
KEETFVYSIFMEEDFGRAFELLTDLVFHSQFPKQEIEKEVDVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDE
GSLLRFDSESGRSFMRRFYAPENMVFFSMGRKDFKNILKSAESALSDISFPMAERIRKAPDPIEACVRQIHKDTHQAHVL
IGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSLREKHGLVYNVESNITSYTDTGLASIYFGTDPKNREKAMRLVHKE
LARLRDVKLSATQLAAAKKQVIGQLGVSGDNREGLFLGLGKSYLHYNRYDTLPEVFAQIEKITAGQILDVANEVFAPERL
FCLIYE

Sequences:

>Translated_406_residues
MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGLAHFVEHMIFKGTEKRKAWHILNRMENVGGELNAYTT
KEETFVYSIFMEEDFGRAFELLTDLVFHSQFPKQEIEKEVDVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDE
GSLLRFDSESGRSFMRRFYAPENMVFFSMGRKDFKNILKSAESALSDISFPMAERIRKAPDPIEACVRQIHKDTHQAHVL
IGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSLREKHGLVYNVESNITSYTDTGLASIYFGTDPKNREKAMRLVHKE
LARLRDVKLSATQLAAAKKQVIGQLGVSGDNREGLFLGLGKSYLHYNRYDTLPEVFAQIEKITAGQILDVANEVFAPERL
FCLIYE
>Mature_406_residues
MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGLAHFVEHMIFKGTEKRKAWHILNRMENVGGELNAYTT
KEETFVYSIFMEEDFGRAFELLTDLVFHSQFPKQEIEKEVDVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDE
GSLLRFDSESGRSFMRRFYAPENMVFFSMGRKDFKNILKSAESALSDISFPMAERIRKAPDPIEACVRQIHKDTHQAHVL
IGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSLREKHGLVYNVESNITSYTDTGLASIYFGTDPKNREKAMRLVHKE
LARLRDVKLSATQLAAAKKQVIGQLGVSGDNREGLFLGLGKSYLHYNRYDTLPEVFAQIEKITAGQILDVANEVFAPERL
FCLIYE

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=411, Percent_Identity=29.4403892944039, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI46593007, Length=398, Percent_Identity=25.8793969849246, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI24308013, Length=428, Percent_Identity=23.5981308411215, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1787770, Length=235, Percent_Identity=26.8085106382979, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=27.5434243176179, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17553678, Length=397, Percent_Identity=23.6775818639798, Blast_Score=104, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323192, Length=403, Percent_Identity=29.0322580645161, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6321813, Length=414, Percent_Identity=20.2898550724638, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357875, Length=397, Percent_Identity=29.9748110831234, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24646943, Length=397, Percent_Identity=29.9748110831234, Blast_Score=178, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46199; Mature: 46199

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGLAHFVEHMIFKGTEKRK
CCCHHHHCCCCCEEEEEECCCCHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHH
AWHILNRMENVGGELNAYTTKEETFVYSIFMEEDFGRAFELLTDLVFHSQFPKQEIEKEV
HHHHHHHHHHCCCCCCEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDEGSLLRFDSESGRSFMRRFYA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHCCCCCCCCCCCEEEECCHHHHHHHHHHCC
PENMVFFSMGRKDFKNILKSAESALSDISFPMAERIRKAPDPIEACVRQIHKDTHQAHVL
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
IGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSLREKHGLVYNVESNITSYTDTGLAS
ECCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEE
IYFGTDPKNREKAMRLVHKELARLRDVKLSATQLAAAKKQVIGQLGVSGDNREGLFLGLG
EEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
KSYLHYNRYDTLPEVFAQIEKITAGQILDVANEVFAPERLFCLIYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MDYIAHTLPNGLRMVHLPVNSPVSYCGFAVNAGTRDENEDEFGLAHFVEHMIFKGTEKRK
CCCHHHHCCCCCEEEEEECCCCHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHH
AWHILNRMENVGGELNAYTTKEETFVYSIFMEEDFGRAFELLTDLVFHSQFPKQEIEKEV
HHHHHHHHHHCCCCCCEEECCCCEEEEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DVILDEINSYEDSPSELIFDEFENLLYKGHALGHNILGDEGSLLRFDSESGRSFMRRFYA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCHHCCCCCCCCCCCEEEECCHHHHHHHHHHCC
PENMVFFSMGRKDFKNILKSAESALSDISFPMAERIRKAPDPIEACVRQIHKDTHQAHVL
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
IGGRAFSMHDKKRIPLFLLNNILGGPGMNNRLNVSLREKHGLVYNVESNITSYTDTGLAS
ECCEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCEE
IYFGTDPKNREKAMRLVHKELARLRDVKLSATQLAAAKKQVIGQLGVSGDNREGLFLGLG
EEECCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECC
KSYLHYNRYDTLPEVFAQIEKITAGQILDVANEVFAPERLFCLIYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]