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The map label for this gene is ruvA

Identifier: 150009258

GI number: 150009258

Start: 3153845

End: 3154435

Strand: Reverse

Name: ruvA

Synonym: BDI_2660

Alternate gene names: 150009258

Gene position: 3154435-3153845 (Counterclockwise)

Preceding gene: 150009259

Following gene: 150009257

Centisome position: 65.56

GC content: 44.67

Gene sequence:

>591_bases
ATGATAGAATATATAAAGGGTGAAATCGTGGAACTTACACCTACACGTATGATTTTGGAGTGTGGTGGTATAGGCTACGA
GCTGAATATATCCTTGAATACATATAGTGCGTTTGGGAACAAGACTACCGGAAAAATATATATATATGAGGTAATCCGGG
AAGATGCTCATTTACTATTTGGCTTTGCCGAGAAAATCGAAAGGGAGTTGTTCCTTTTGCTTACTTCCGTTTCTGGAGTG
GGACCGAATACCGCACGCATGATCCTTTCTTCTCTACCGCCATCCGAATTGGTTCAAGTGATCGGTTCGAAGAATGAGGC
CGCATTGACTGCCGTGAAAGGGATTGGTTTGAAGACGGCCCAGCGTATCTTGGTAGATTTGAAAAATAAGGTGAAACCTA
TGGAGAGTATGGCCGGAAACTTGCCGGAGGCATCAGTCTCTAATGGAGCGGTAACCGAGGAGGCCGTAGCCGCATTGGTT
ATGTTAGGTTTCCAGAAAGCGGCTTCGCAAAAAGCGGTATCCGCTATTTTGAAAGGCTCGCCCACTTTAGCTGTGGAACA
AGTAATTAAAACTGCGCTTAGAATGCTTTGA

Upstream 100 bases:

>100_bases
ACCTTTAAGGTTCCTTATCCGGGAAAAGAATGGTAACCCGATATACGTTTTTGATTAATTTTGCGTTATAATAGGTACGG
AATATTAAAAAGATATATAG

Downstream 100 bases:

>100_bases
TAATTGACAATTGAGGATTAACGATTAACAATTGACAATTAAATGAGAAAATGAGAAAACGAATACTGAAATATTCCATA
TGGATCGTTGTATTATTGTT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTGKIYIYEVIREDAHLLFGFAEKIERELFLLLTSVSGV
GPNTARMILSSLPPSELVQVIGSKNEAALTAVKGIGLKTAQRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALV
MLGFQKAASQKAVSAILKGSPTLAVEQVIKTALRML

Sequences:

>Translated_196_residues
MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTGKIYIYEVIREDAHLLFGFAEKIERELFLLLTSVSGV
GPNTARMILSSLPPSELVQVIGSKNEAALTAVKGIGLKTAQRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALV
MLGFQKAASQKAVSAILKGSPTLAVEQVIKTALRML
>Mature_196_residues
MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTGKIYIYEVIREDAHLLFGFAEKIERELFLLLTSVSGV
GPNTARMILSSLPPSELVQVIGSKNEAALTAVKGIGLKTAQRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALV
MLGFQKAASQKAVSAILKGSPTLAVEQVIKTALRML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=34.4827586206897, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PARD8 (A6LFB5)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001304001.1
- ProteinModelPortal:   A6LFB5
- SMR:   A6LFB5
- STRING:   A6LFB5
- GeneID:   5307809
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2660
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- ProtClustDB:   PRK00116
- BioCyc:   PDIS435591:BDI_2660-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 20998; Mature: 20998

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTGKIYIYEVIREDAHLLF
CCCCCCCCEEEECCHHHHEEECCCCEEEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHH
GFAEKIERELFLLLTSVSGVGPNTARMILSSLPPSELVQVIGSKNEAALTAVKGIGLKTA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCHHHH
QRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALVMLGFQKAASQKAVSAILKGS
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTLAVEQVIKTALRML
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIEYIKGEIVELTPTRMILECGGIGYELNISLNTYSAFGNKTTGKIYIYEVIREDAHLLF
CCCCCCCCEEEECCHHHHEEECCCCEEEEEEEEEEECCCCCCCCEEEEHHHHHHHHHHHH
GFAEKIERELFLLLTSVSGVGPNTARMILSSLPPSELVQVIGSKNEAALTAVKGIGLKTA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHCCCHHHH
QRILVDLKNKVKPMESMAGNLPEASVSNGAVTEEAVAALVMLGFQKAASQKAVSAILKGS
HHHHHHHHHHCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTLAVEQVIKTALRML
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA