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The map label for this gene is lpxB [H]

Identifier: 150009234

GI number: 150009234

Start: 3117527

End: 3118660

Strand: Direct

Name: lpxB [H]

Synonym: BDI_2636

Alternate gene names: 150009234

Gene position: 3117527-3118660 (Clockwise)

Preceding gene: 150009233

Following gene: 150009235

Centisome position: 64.79

GC content: 49.56

Gene sequence:

>1134_bases
ATGAAGTATTACCTGATAGCCGGAGAAGCCTCCGGAGACCTGCACGCCTCGAATTTGATGGCAGCCCTGAAAGAGAATGA
CCCGAAGGCCGAGTTCCGCTTTCTGGGCGGCGATCTGATGAGAGCCGTCGGAGGAACCCTTGTCAAACATTACCGGGAAA
TGGCGTTCATGGGCTTTATCCCGGTATTGCTGAACTTGCGCACCATCTTAAATAACATGAAGACGTGCCAAGAGGATATC
CGCCGCTATCAACCAGATGTCGTCATCTTAATTGACTACCCGGGATTCAACCTGAAGATCGCCAAATATGTGAAAACCCA
ATTGGGTCTCCCGGTATATTACTATATATCCCCCAAGATATGGGCCTGGAAACAATACCGCATCAGGGACTTCCGGCGTT
ATGTAGATCGTATGTTCTGCATCCTGCCGTTCGAGACCGAGTTTTTCCGGAAGCTTAATTATTCGGTAGATTACGTAGGA
AATCCTTCTGTAGACTCCGTAGCCTATTACAAGGAGCATCAAGCGATCCCCAAAGATACATTTATCAAAGAGGAAGGATT
GGCCAACAAGCCTATCCTCGCCTTGCTATCCGGTAGCCGCAAACAAGAGATCAAGGATAATTTACCGACCATGCTGAAAG
TAGCCTCCGCATATCCCGACTACCAGCCGGTAATAGCCGGAGCACCAGGCATCGATCCTGCCTACTATCAAGAATACATA
GGCTCTTATCCTGCCAAGATCGTGTTTGGTAAAACCTATCCCTTGCTACAACATAGTGCCGCCGCCTTGGTAACCTCCGG
CACGGCAACCTTGGAAACCGCCCTGTTCCGGGTTCCGCAAGTCGTTTGCTACTACGTCGTAGCCGGACAGTTGGCCAGCT
TTATTTTCAAGCATTTCTTCCATACGAAATACATATCCCTCGTGAACCTGATCGGGGGACGGGAGATCGTACAAGAACTA
TTCGGAGCCCGCTTCTCCGAATCGCAAATACAAGACGAGCTAGGACGCATCCTACAAGATCCAGCCTATCGAAAACGAAT
GCTAGACGGATACGACAAGATTATCCATACGCTAGGAATGCCCGGGGCTTCAAAGCGTACGGCACGGCTAATCGTTGAAT
CCCTTGGTTCTTAA

Upstream 100 bases:

>100_bases
CGCCTCCCTAGTCCCCTGCAAGATTGACGTTACGGACTACGACTTCATGGCCACCCTAAACAACTGGATCCTTTAATTCT
CAATTCTCAATTTTCAATTC

Downstream 100 bases:

>100_bases
CATCTTTTATTAACGTCTTTTGCAGCATTTCACCCCGAACTTACATCTTTCTTCATAGAACGATGAAATGTGAACTTTTT
AAGAAACAAAAGGAATGAAG

Product: glycosyltransferase family lipid-alpha-disaccharide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVGGTLVKHYREMAFMGFIPVLLNLRTILNNMKTCQEDI
RRYQPDVVILIDYPGFNLKIAKYVKTQLGLPVYYYISPKIWAWKQYRIRDFRRYVDRMFCILPFETEFFRKLNYSVDYVG
NPSVDSVAYYKEHQAIPKDTFIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAYPDYQPVIAGAPGIDPAYYQEYI
GSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALFRVPQVVCYYVVAGQLASFIFKHFFHTKYISLVNLIGGREIVQEL
FGARFSESQIQDELGRILQDPAYRKRMLDGYDKIIHTLGMPGASKRTARLIVESLGS

Sequences:

>Translated_377_residues
MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVGGTLVKHYREMAFMGFIPVLLNLRTILNNMKTCQEDI
RRYQPDVVILIDYPGFNLKIAKYVKTQLGLPVYYYISPKIWAWKQYRIRDFRRYVDRMFCILPFETEFFRKLNYSVDYVG
NPSVDSVAYYKEHQAIPKDTFIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAYPDYQPVIAGAPGIDPAYYQEYI
GSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALFRVPQVVCYYVVAGQLASFIFKHFFHTKYISLVNLIGGREIVQEL
FGARFSESQIQDELGRILQDPAYRKRMLDGYDKIIHTLGMPGASKRTARLIVESLGS
>Mature_377_residues
MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVGGTLVKHYREMAFMGFIPVLLNLRTILNNMKTCQEDI
RRYQPDVVILIDYPGFNLKIAKYVKTQLGLPVYYYISPKIWAWKQYRIRDFRRYVDRMFCILPFETEFFRKLNYSVDYVG
NPSVDSVAYYKEHQAIPKDTFIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAYPDYQPVIAGAPGIDPAYYQEYI
GSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALFRVPQVVCYYVVAGQLASFIFKHFFHTKYISLVNLIGGREIVQEL
FGARFSESQIQDELGRILQDPAYRKRMLDGYDKIIHTLGMPGASKRTARLIVESLGS

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0763

COG function: function code M; Lipid A disaccharide synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxB family [H]

Homologues:

Organism=Escherichia coli, GI1786379, Length=338, Percent_Identity=33.4319526627219, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835 [H]

Pfam domain/function: PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 42879; Mature: 42879

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVGGTLVKHYREMAFMGFI
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVLLNLRTILNNMKTCQEDIRRYQPDVVILIDYPGFNLKIAKYVKTQLGLPVYYYISPKI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCE
WAWKQYRIRDFRRYVDRMFCILPFETEFFRKLNYSVDYVGNPSVDSVAYYKEHQAIPKDT
EEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCHH
FIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAYPDYQPVIAGAPGIDPAYYQEYI
CCCCCCCCCCCHHEECCCCCHHHHHHCCHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHH
GSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALFRVPQVVCYYVVAGQLASFIFKHFF
CCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTKYISLVNLIGGREIVQELFGARFSESQIQDELGRILQDPAYRKRMLDGYDKIIHTLGM
HHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PGASKRTARLIVESLGS
CCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKYYLIAGEASGDLHASNLMAALKENDPKAEFRFLGGDLMRAVGGTLVKHYREMAFMGFI
CEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVLLNLRTILNNMKTCQEDIRRYQPDVVILIDYPGFNLKIAKYVKTQLGLPVYYYISPKI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCE
WAWKQYRIRDFRRYVDRMFCILPFETEFFRKLNYSVDYVGNPSVDSVAYYKEHQAIPKDT
EEHHHHHHHHHHHHHHHHHEECCCCHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCHH
FIKEEGLANKPILALLSGSRKQEIKDNLPTMLKVASAYPDYQPVIAGAPGIDPAYYQEYI
CCCCCCCCCCCHHEECCCCCHHHHHHCCHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHH
GSYPAKIVFGKTYPLLQHSAAALVTSGTATLETALFRVPQVVCYYVVAGQLASFIFKHFF
CCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTKYISLVNLIGGREIVQELFGARFSESQIQDELGRILQDPAYRKRMLDGYDKIIHTLGM
HHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
PGASKRTARLIVESLGS
CCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA