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The map label for this gene is kdsB [H]

Identifier: 150009229

GI number: 150009229

Start: 3108879

End: 3109700

Strand: Reverse

Name: kdsB [H]

Synonym: BDI_2631

Alternate gene names: 150009229

Gene position: 3109700-3108879 (Counterclockwise)

Preceding gene: 150009230

Following gene: 150009228

Centisome position: 64.63

GC content: 46.35

Gene sequence:

>822_bases
ATGGAAAAAGTACTGATTGTAATACCGGCTCGATATGGTTCAAGCCGGTTGCCGGGTAAGCCTTTGGTTAAGATTAAAGG
TATAGAGATGATAAAACGGGTCTCGGATATAGCGGATTTTGTATGTCGCAAAAATGAGTCTTGTTCTTATTTGGTAGCTA
CGGATGATGAGCGCATCGTCTCGTTTTGCGAATCCCGGGAGATTCCGGTGATGATGACTTCCACGAATTGTAAAAGTGGT
ACGGAACGTTGCTATGAGGCGGCAAGGAAACAGGACACCAATCCCGGACTGATAATAAATCTGCAAGGCGATAATCCCAC
GTGTCCTCCTTGGATCTTGCAAGATCTGATCGATACATGGAGAAAGGAGAAGGCGGATGTCCTTACCGCCTCGGTCTTGT
TGGGATGGAGCGAATACGATCAATTACTGGCGATGAAAAAGGAAACCCCTTATTCTGGCACGACGGTATTGGTGGATCGG
CTGGGATATGCCTTAGCTTTCTCGAAACAAACCATACCCGCTATCCGTAAGGAGGATCAGGCTAGGGATCTTTTGCCTAA
AAGCCCTGTCAGGCGGCATGTGGGTTTATATGCGTATAGCGGTCGAGCCCTTGAGTCTTATTTCTCATTACCTCCGTCTG
TGTATGAACGCTCTTATATAGAAGGATTGGAACAGATGCGTTTCTTAGAGAATGGTATCAAAATGAGGGTCGTAGACGTT
GATTATCGGGGACGTGAGACAACAAGCGGGGTTGATTCCCCGGAAGATGTTAAACGGGTTGAGGAAATACTTGAGAAATA
TGGAGAGTTCGATCTTTCGTGA

Upstream 100 bases:

>100_bases
GTGCGGCGGATGATCATACAAAGGACCCTCAATACTCTGATTGTATTACATATTATAAAATTAAACGGTTTAGAATGTTA
ATCTATTAAATGAAGTGATT

Downstream 100 bases:

>100_bases
CTTAGATGGAATCGTAGATTCTATTTTATTTCCTTACCATACTTTGGAGGAAGTTCTACCTCCTGGCTGTGAGGCTGGTC
CGGTATGGATGGAATTTGCC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEKVLIVIPARYGSSRLPGKPLVKIKGIEMIKRVSDIADFVCRKNESCSYLVATDDERIVSFCESREIPVMMTSTNCKSG
TERCYEAARKQDTNPGLIINLQGDNPTCPPWILQDLIDTWRKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDR
LGYALAFSKQTIPAIRKEDQARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERSYIEGLEQMRFLENGIKMRVVDV
DYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS

Sequences:

>Translated_273_residues
MEKVLIVIPARYGSSRLPGKPLVKIKGIEMIKRVSDIADFVCRKNESCSYLVATDDERIVSFCESREIPVMMTSTNCKSG
TERCYEAARKQDTNPGLIINLQGDNPTCPPWILQDLIDTWRKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDR
LGYALAFSKQTIPAIRKEDQARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERSYIEGLEQMRFLENGIKMRVVDV
DYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS
>Mature_273_residues
MEKVLIVIPARYGSSRLPGKPLVKIKGIEMIKRVSDIADFVCRKNESCSYLVATDDERIVSFCESREIPVMMTSTNCKSG
TERCYEAARKQDTNPGLIINLQGDNPTCPPWILQDLIDTWRKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDR
LGYALAFSKQTIPAIRKEDQARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERSYIEGLEQMRFLENGIKMRVVDV
DYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=258, Percent_Identity=35.2713178294574, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 30996; Mature: 30996

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKVLIVIPARYGSSRLPGKPLVKIKGIEMIKRVSDIADFVCRKNESCSYLVATDDERIV
CCEEEEEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SFCESREIPVMMTSTNCKSGTERCYEAARKQDTNPGLIINLQGDNPTCPPWILQDLIDTW
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
RKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDRLGYALAFSKQTIPAIRKEDQ
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCH
ARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERSYIEGLEQMRFLENGIKMRVVDV
HHHCCCCCHHHHHHCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEKVLIVIPARYGSSRLPGKPLVKIKGIEMIKRVSDIADFVCRKNESCSYLVATDDERIV
CCEEEEEEECCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SFCESREIPVMMTSTNCKSGTERCYEAARKQDTNPGLIINLQGDNPTCPPWILQDLIDTW
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
RKEKADVLTASVLLGWSEYDQLLAMKKETPYSGTTVLVDRLGYALAFSKQTIPAIRKEDQ
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCH
ARDLLPKSPVRRHVGLYAYSGRALESYFSLPPSVYERSYIEGLEQMRFLENGIKMRVVDV
HHHCCCCCHHHHHHCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
DYRGRETTSGVDSPEDVKRVEEILEKYGEFDLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA