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The map label for this gene is aslA [H]

Identifier: 150009207

GI number: 150009207

Start: 3086035

End: 3087582

Strand: Direct

Name: aslA [H]

Synonym: BDI_2609

Alternate gene names: 150009207

Gene position: 3086035-3087582 (Clockwise)

Preceding gene: 150009206

Following gene: 150009208

Centisome position: 64.14

GC content: 52.52

Gene sequence:

>1548_bases
ATGAAATCAACACTTATCGTAGGGATCGGTGCCTCGCTTCTTACAGCCGGTATCGCAAAAGCCCAACAGAGACAAGACAT
TACACCTAGAACGCCAAACGTATTGTTCATCTATGCGGATGACTTGGGATATGGAGACTTGGAATGCTACGACGGCACGC
AAGTGAAAACCCCGAATATCAACCGGCTCGCCAAGAACGGTATCCGCTTCACCAACGCTCACGCAACCGCCTCTACCAGT
ACGCCCTCCCGATATTCCATGCTAACCGGAGAGTACGCATGGCGCCGCCCGGGAACGGACATCGCCGCAGGAAACGCCGG
AATGATCATACGACCGGAGCGTTATACGATAGCCGATATGTTCAAGAACGCGGGATACGCCACGGCCGCTATCGGCAAAT
GGCATCTTGGCCTAGGAGACAAAGCGGGCGAGCAAGACTGGAACGCCCCACTCCCCACCGCCCTTGGCGATCTGGGATTT
GATTATTCCTATATCATGGCGGCGACGGCAGACCGCGTCCCCTGCGTATTCATCGAGAACGGGCAGGTGGCGAACTACGA
TCCGGATGCCCCGATCTATGTCAGTTACCAGAAGAACTTTCCCGGAGAGCCGACCGGAAAAGATAATCCGGAATTATTAT
ACAACCAGAAGCCTAGTTTCGGGCACGACCAATCCATCGTAAACGGAATCAGCCGTATCGGTTACATGAAAGGTGGCGGC
AAGGCGCTTTGGAAAGACGAGAATATCGCCGATTCTATCGTGACACACGCCATCGATTTTATCAAGGAGAATAAAGAGAA
GCCTTTCTTCATGTATTTCGCCACGAACGACGTGCATGTACCCCGCTTCCCGCACGACCGTTTCCGGGGAAAGAACCCGA
TGGGCGTGAGGGGCGACGCTATCGAGCAATTCGACTGGAGCGTAGGCCAATTGATGAAAACATTGGATGAGATGGGATTG
ACGGAAAACACCTTGATCATCTTGTCAAGCGACAACGGACCTGTCGTAGACGATGGTTACGCGGACCGGGCCGTGGAGCT
ATTAGGCGATCATAAACCCGCCGGCCCGCTTAGAGGTAATAAATACAGTGCCTTCGAAGGGGGAACCCGTATCCCGGCTA
TCGTACATTGGCCAAAGGAGATCAAGCAAGCCGCCGTATCAGATGCGCTAGTGAGCCAGATCGACTGGTTCGCCTCCCTT
GCCTCACTGACGAATTCCCGTCTTCCGAAAGGAAGCGCGCCGGATAGTTATGATTATCTGGATACTTGGATCGGGAAAAG
CAAGGAAGACCGCCCGTGGGTAATCGAGCAAGCGCTTAATAAGGCACTCTCCGTCCGTACGAAAGATTGGAAATATATCG
AGCCGAGCGTAGGTTCCGCTATCATGGAATATGAGAAGATTGAGACCGGATATTCCCCCGAGCCTCAGTTATACGACATG
ACGAAGGTCTACGAGGAAGGAAACAAGGCCTTGCAACATCCGGAGATCGTTTTCCAATTGCAGGGAATCTTAAAAGGAGT
TCGGGATCACACTATCAAGGCTAAATAA

Upstream 100 bases:

>100_bases
TCCGATTTTGATAAATACCAGACAGATAACCTTCTTGATTTTGATAACGAAATAGAGTCATAATACAAACTCTTTATAGA
ACATCTAAATAATAAACAAC

Downstream 100 bases:

>100_bases
TGGAAAGAAGAAACTTCATTAAATCATCCCTCGGAATCGGTCTGGGTGCGACACTTCCGGGGATGACGCATAGCAAAAGC
GGGAAAGAGGCAGAGACCGC

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGYGDLECYDGTQVKTPNINRLAKNGIRFTNAHATASTS
TPSRYSMLTGEYAWRRPGTDIAAGNAGMIIRPERYTIADMFKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGF
DYSYIMAATADRVPCVFIENGQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKPSFGHDQSIVNGISRIGYMKGGG
KALWKDENIADSIVTHAIDFIKENKEKPFFMYFATNDVHVPRFPHDRFRGKNPMGVRGDAIEQFDWSVGQLMKTLDEMGL
TENTLIILSSDNGPVVDDGYADRAVELLGDHKPAGPLRGNKYSAFEGGTRIPAIVHWPKEIKQAAVSDALVSQIDWFASL
ASLTNSRLPKGSAPDSYDYLDTWIGKSKEDRPWVIEQALNKALSVRTKDWKYIEPSVGSAIMEYEKIETGYSPEPQLYDM
TKVYEEGNKALQHPEIVFQLQGILKGVRDHTIKAK

Sequences:

>Translated_515_residues
MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGYGDLECYDGTQVKTPNINRLAKNGIRFTNAHATASTS
TPSRYSMLTGEYAWRRPGTDIAAGNAGMIIRPERYTIADMFKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGF
DYSYIMAATADRVPCVFIENGQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKPSFGHDQSIVNGISRIGYMKGGG
KALWKDENIADSIVTHAIDFIKENKEKPFFMYFATNDVHVPRFPHDRFRGKNPMGVRGDAIEQFDWSVGQLMKTLDEMGL
TENTLIILSSDNGPVVDDGYADRAVELLGDHKPAGPLRGNKYSAFEGGTRIPAIVHWPKEIKQAAVSDALVSQIDWFASL
ASLTNSRLPKGSAPDSYDYLDTWIGKSKEDRPWVIEQALNKALSVRTKDWKYIEPSVGSAIMEYEKIETGYSPEPQLYDM
TKVYEEGNKALQHPEIVFQLQGILKGVRDHTIKAK
>Mature_515_residues
MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGYGDLECYDGTQVKTPNINRLAKNGIRFTNAHATASTS
TPSRYSMLTGEYAWRRPGTDIAAGNAGMIIRPERYTIADMFKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGF
DYSYIMAATADRVPCVFIENGQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKPSFGHDQSIVNGISRIGYMKGGG
KALWKDENIADSIVTHAIDFIKENKEKPFFMYFATNDVHVPRFPHDRFRGKNPMGVRGDAIEQFDWSVGQLMKTLDEMGL
TENTLIILSSDNGPVVDDGYADRAVELLGDHKPAGPLRGNKYSAFEGGTRIPAIVHWPKEIKQAAVSDALVSQIDWFASL
ASLTNSRLPKGSAPDSYDYLDTWIGKSKEDRPWVIEQALNKALSVRTKDWKYIEPSVGSAIMEYEKIETGYSPEPQLYDM
TKVYEEGNKALQHPEIVFQLQGILKGVRDHTIKAK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI53831991, Length=499, Percent_Identity=29.4589178356713, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI146229331, Length=474, Percent_Identity=29.1139240506329, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI146229329, Length=474, Percent_Identity=29.1139240506329, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI6005990, Length=474, Percent_Identity=29.1139240506329, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI146229324, Length=474, Percent_Identity=29.1139240506329, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI157266309, Length=441, Percent_Identity=28.7981859410431, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI71852584, Length=427, Percent_Identity=28.1030444964871, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI4503899, Length=418, Percent_Identity=28.2296650717703, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI58743319, Length=502, Percent_Identity=27.8884462151394, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI45430057, Length=426, Percent_Identity=29.1079812206573, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI71852586, Length=327, Percent_Identity=28.7461773700306, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI146229327, Length=404, Percent_Identity=25.990099009901, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI109389362, Length=407, Percent_Identity=26.5356265356265, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI38569407, Length=411, Percent_Identity=26.7639902676399, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI38569405, Length=411, Percent_Identity=26.7639902676399, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI31742482, Length=164, Percent_Identity=34.7560975609756, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI59797060, Length=117, Percent_Identity=35.8974358974359, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790233, Length=453, Percent_Identity=25.8278145695364, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790112, Length=115, Percent_Identity=37.3913043478261, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081924, Length=525, Percent_Identity=22.4761904761905, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533416, Length=446, Percent_Identity=27.5784753363229, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115533418, Length=439, Percent_Identity=26.6514806378132, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17559078, Length=304, Percent_Identity=26.6447368421053, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666175, Length=425, Percent_Identity=25.1764705882353, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666109, Length=519, Percent_Identity=22.9287090558767, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366397, Length=400, Percent_Identity=25.75, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366395, Length=400, Percent_Identity=25.75, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666163, Length=400, Percent_Identity=25.75, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363223, Length=113, Percent_Identity=35.3982300884956, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 56992; Mature: 56992

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGYGDLECYDGTQVKTPNI
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCEECCCCH
NRLAKNGIRFTNAHATASTSTPSRYSMLTGEYAWRRPGTDIAAGNAGMIIRPERYTIADM
HHHHHCCCEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCEECCCCCEEECCCCCHHHHH
FKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGFDYSYIMAATADRVPCVFIEN
HHCCCCEEEEECEEEECCCCCCCCCCCCCCCCHHHHHCCCCHHHHEEECCCCCCEEEEEC
GQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKPSFGHDQSIVNGISRIGYMKGGG
CEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCEECCCC
KALWKDENIADSIVTHAIDFIKENKEKPFFMYFATNDVHVPRFPHDRFRGKNPMGVRGDA
CEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHHHCCCCCCCCCCCH
IEQFDWSVGQLMKTLDEMGLTENTLIILSSDNGPVVDDGYADRAVELLGDHKPAGPLRGN
HHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
KYSAFEGGTRIPAIVHWPKEIKQAAVSDALVSQIDWFASLASLTNSRLPKGSAPDSYDYL
EEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DTWIGKSKEDRPWVIEQALNKALSVRTKDWKYIEPSVGSAIMEYEKIETGYSPEPQLYDM
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCHHHH
TKVYEEGNKALQHPEIVFQLQGILKGVRDHTIKAK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKSTLIVGIGASLLTAGIAKAQQRQDITPRTPNVLFIYADDLGYGDLECYDGTQVKTPNI
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEECCCCEECCCCH
NRLAKNGIRFTNAHATASTSTPSRYSMLTGEYAWRRPGTDIAAGNAGMIIRPERYTIADM
HHHHHCCCEEEECCCCCCCCCCCHHEEECCCCCCCCCCCCEECCCCCEEECCCCCHHHHH
FKNAGYATAAIGKWHLGLGDKAGEQDWNAPLPTALGDLGFDYSYIMAATADRVPCVFIEN
HHCCCCEEEEECEEEECCCCCCCCCCCCCCCCHHHHHCCCCHHHHEEECCCCCCEEEEEC
GQVANYDPDAPIYVSYQKNFPGEPTGKDNPELLYNQKPSFGHDQSIVNGISRIGYMKGGG
CEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCEECCCC
KALWKDENIADSIVTHAIDFIKENKEKPFFMYFATNDVHVPRFPHDRFRGKNPMGVRGDA
CEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECCCCCHHHHCCCCCCCCCCCH
IEQFDWSVGQLMKTLDEMGLTENTLIILSSDNGPVVDDGYADRAVELLGDHKPAGPLRGN
HHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
KYSAFEGGTRIPAIVHWPKEIKQAAVSDALVSQIDWFASLASLTNSRLPKGSAPDSYDYL
EEECCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DTWIGKSKEDRPWVIEQALNKALSVRTKDWKYIEPSVGSAIMEYEKIETGYSPEPQLYDM
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCHHHH
TKVYEEGNKALQHPEIVFQLQGILKGVRDHTIKAK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]