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The map label for this gene is spoVD [H]

Identifier: 150009091

GI number: 150009091

Start: 2937963

End: 2940158

Strand: Reverse

Name: spoVD [H]

Synonym: BDI_2492

Alternate gene names: 150009091

Gene position: 2940158-2937963 (Counterclockwise)

Preceding gene: 150009092

Following gene: 150009090

Centisome position: 61.11

GC content: 52.69

Gene sequence:

>2196_bases
ATGTCTGAAGAAAACGAACCGAAAGAAATAGAGCCTAAAGGTAGCCGGATTTTATTCTGTTACTTCGTGGTCGTGCTGTT
GCTGGGGCTTGTGGCCGTAGGAATCCTGTTCCGTGCCTTTGATACGGCCTTCGTGGAGAGGGATAAATGGATGAAGGTGG
CCGAGAGCCAGAAACGACCGAACCGTTTGGTGTTGCCCGGACGTGGCAATATCTATTCGTCGGACGGTAAGTTGATGGCT
ACCAGCGTGCCTCGTTATTATATGTATATCGACTTTAAGGCGGATGCGTATACTCCGGCTAAGGGTGCCAAGTATAATTG
GCTGGATACGTTCAAGACGTCCAAGAAGGATGGGGTGGACTCGTTGGCGTTTTATCTTTCCCGTAAATTGAAGGATCGTA
CGCCGGCGGGCTATAAGGCTTATCTGCTGAAAGGGCTGAGCGGTAAAAGCCGCCAGTTCCCGATTTACGCGGGGAAGGTC
TCGTATTCGGATTTGAAGGAGATCCGTAAGTTCCCGTTCCTTCGTCTGGGACGTTATAAGAGCGGTTTTTATACGAAGGA
GATGGTGCAGCGCCAGAAACCTTTCGGGACCTTGGCGTCTCGTACGATCGGTGATATCTACGGAGAGATCGAGGAGGGTG
GAACTACAAAGGGGAAGAATGGATTGGAGTTGCAATACGATTCGCTCCTGCGGGGGCAGGCCGGGTTGAGTTCCGTTCGC
CGTGTCGGTGGAGGCTGGACGAACGTGATCGAGGTGGATCCGGTGGATGGCATGGATATTCGCACCACGATCGATATCAA
TATACAGGATATAACCGAGAAATCGCTGGTCGATAAATTGAAGGCGATCGATGCCGAGTCTGGTACGGCTGTCGTGATGG
AGGTCGAGACCGGAGAGATCAAGGCGATCACGAATATGGGGCGTATCCGTGAGGGCGTATATGGCGAGACGAAGAATCAT
GCCGTGGCGGACGAGATCGAGCCGGGCTCTACTTTCAAGGTGGCCTCTATCATGGTGGCCTTGGAGGATGGTTTATGCAA
TCCGGGAGATACGGTCGATGTAGGCAATGGTATATATATGTATAAGGGTGCCCGCATGACGGACCATAATATGAATAAAG
GCGGATACGGTCGGATCTCGGTGGAGCAGGCGATTTGGTATTCCTCCAATATCGGTGTGGCCAAGACGATCCTGAAAGGT
TATTCGGATAACCCGACGAAGTTTGTGGAGGGACTGTACCGTATCGGTATGAACGCGGATCTTCGTTTGGAGATACCGGG
GGCGGGACGTGCCAAGATACGTCGCCCGGATGATACGACCCGTTATTGGTCCAAGACCACTTTGCCTTGGATGTCGTTCG
GCTACGAGACGCAGGTACCGCCGATCAATACGCTGGCGTTCTTTAACGCGATCGCGAACAACGGAAAGATGGTTCGCCCG
ATGTTTACGAAAGAGATCTTACATAACGGCAAGACCGTGCAGAGTTTTTCCACGGAGGTGATCAACTCTTCGATCTGCTC
GGATCATACGCTGGCGTTGATAAAAGATATGTTGCTGGGAGTCGTGGAGAAAGGGACCGGTAAGGCGGTTCATTCGGATA
TTGTCCGGATCGCCGGAAAGACCGGTACGGCGCAGATCGCTACGGGCGGTGTCTACCGTACGAGCGGGCACCAAGTCTCT
TTCTGTGGCTATTTCCCGGCCGATCATCCGAAGTATTCTTGTATCGTGGTGATCCGCCGTCCTCGTATCGGTTATCCTTC
GGGTGGTACGATGTCGGGAGGCGTGGTGCGTGCGATCGCCGAGAAGATATACGCCAGCCATATGTCGTTCGATGTCCGGG
ATATGGAACGGGATTCGATGGCCGTGATGGTACCTCGTGTGAAAGGCGGCGACCTGAGGGCGGTAGAGGAAGTATTAGAT
GAATTGGATATTAAGGCGGATACGGACAGTTTGGAGACAAAGTGGGTCGTAGCCTCCGCCGAGCAAGAAGAGAATAAGGT
GAAATTAAGCGATCTGACGATTCGTGAGGGACTGGTACCCCGGGTAGTCGGCATGGGTGCTAAAGATGCGGTTTTCTTGT
TGGAGCAAGCCGGTCTGCGTGTCTCTTTGTCGGGTGTCGGACGGGTCGTTTCGCAGAGTATTCAACCCGGACAGCGAGTG
TCTAAGGGGCAGACCGTATTATTAACATTGAAATAG

Upstream 100 bases:

>100_bases
ATCGCAAATCGAGTTGCTGATCGAGGAGCAAGGTATTGATCTGGAGGGTGCGAAAACCCCTCCTTATGAGTTATATAAGT
GAGATAAGGTGTAAATAGGT

Downstream 100 bases:

>100_bases
GTATGGAACTAAGGGATTTAATCGGTGCGTTGGAAGCTCCTATGTTGATGGGGGCGGATAATGTGGATATCACGAATATT
CAATCAGACTCTCGTCGGGT

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MSEENEPKEIEPKGSRILFCYFVVVLLLGLVAVGILFRAFDTAFVERDKWMKVAESQKRPNRLVLPGRGNIYSSDGKLMA
TSVPRYYMYIDFKADAYTPAKGAKYNWLDTFKTSKKDGVDSLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKV
SYSDLKEIRKFPFLRLGRYKSGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKGKNGLELQYDSLLRGQAGLSSVR
RVGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSLVDKLKAIDAESGTAVVMEVETGEIKAITNMGRIREGVYGETKNH
AVADEIEPGSTFKVASIMVALEDGLCNPGDTVDVGNGIYMYKGARMTDHNMNKGGYGRISVEQAIWYSSNIGVAKTILKG
YSDNPTKFVEGLYRIGMNADLRLEIPGAGRAKIRRPDDTTRYWSKTTLPWMSFGYETQVPPINTLAFFNAIANNGKMVRP
MFTKEILHNGKTVQSFSTEVINSSICSDHTLALIKDMLLGVVEKGTGKAVHSDIVRIAGKTGTAQIATGGVYRTSGHQVS
FCGYFPADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIAEKIYASHMSFDVRDMERDSMAVMVPRVKGGDLRAVEEVLD
ELDIKADTDSLETKWVVASAEQEENKVKLSDLTIREGLVPRVVGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRV
SKGQTVLLTLK

Sequences:

>Translated_731_residues
MSEENEPKEIEPKGSRILFCYFVVVLLLGLVAVGILFRAFDTAFVERDKWMKVAESQKRPNRLVLPGRGNIYSSDGKLMA
TSVPRYYMYIDFKADAYTPAKGAKYNWLDTFKTSKKDGVDSLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKV
SYSDLKEIRKFPFLRLGRYKSGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKGKNGLELQYDSLLRGQAGLSSVR
RVGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSLVDKLKAIDAESGTAVVMEVETGEIKAITNMGRIREGVYGETKNH
AVADEIEPGSTFKVASIMVALEDGLCNPGDTVDVGNGIYMYKGARMTDHNMNKGGYGRISVEQAIWYSSNIGVAKTILKG
YSDNPTKFVEGLYRIGMNADLRLEIPGAGRAKIRRPDDTTRYWSKTTLPWMSFGYETQVPPINTLAFFNAIANNGKMVRP
MFTKEILHNGKTVQSFSTEVINSSICSDHTLALIKDMLLGVVEKGTGKAVHSDIVRIAGKTGTAQIATGGVYRTSGHQVS
FCGYFPADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIAEKIYASHMSFDVRDMERDSMAVMVPRVKGGDLRAVEEVLD
ELDIKADTDSLETKWVVASAEQEENKVKLSDLTIREGLVPRVVGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRV
SKGQTVLLTLK
>Mature_730_residues
SEENEPKEIEPKGSRILFCYFVVVLLLGLVAVGILFRAFDTAFVERDKWMKVAESQKRPNRLVLPGRGNIYSSDGKLMAT
SVPRYYMYIDFKADAYTPAKGAKYNWLDTFKTSKKDGVDSLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKVS
YSDLKEIRKFPFLRLGRYKSGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKGKNGLELQYDSLLRGQAGLSSVRR
VGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSLVDKLKAIDAESGTAVVMEVETGEIKAITNMGRIREGVYGETKNHA
VADEIEPGSTFKVASIMVALEDGLCNPGDTVDVGNGIYMYKGARMTDHNMNKGGYGRISVEQAIWYSSNIGVAKTILKGY
SDNPTKFVEGLYRIGMNADLRLEIPGAGRAKIRRPDDTTRYWSKTTLPWMSFGYETQVPPINTLAFFNAIANNGKMVRPM
FTKEILHNGKTVQSFSTEVINSSICSDHTLALIKDMLLGVVEKGTGKAVHSDIVRIAGKTGTAQIATGGVYRTSGHQVSF
CGYFPADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIAEKIYASHMSFDVRDMERDSMAVMVPRVKGGDLRAVEEVLDE
LDIKADTDSLETKWVVASAEQEENKVKLSDLTIREGLVPRVVGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRVS
KGQTVLLTLK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=614, Percent_Identity=24.7557003257329, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 80551; Mature: 80419

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEENEPKEIEPKGSRILFCYFVVVLLLGLVAVGILFRAFDTAFVERDKWMKVAESQKRP
CCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NRLVLPGRGNIYSSDGKLMATSVPRYYMYIDFKADAYTPAKGAKYNWLDTFKTSKKDGVD
CEEEECCCCCEECCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHH
SLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKVSYSDLKEIRKFPFLRLGRYK
HHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCCEEECCCCHHHHHHHHHCCCEEECCCC
SGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKGKNGLELQYDSLLRGQAGLSSVR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHHHHH
RVGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSLVDKLKAIDAESGTAVVMEVETGEI
HHCCCCCCEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
KAITNMGRIREGVYGETKNHAVADEIEPGSTFKVASIMVALEDGLCNPGDTVDVGNGIYM
EEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHEEEEHHCCCCCCCCEEECCCCEEE
YKGARMTDHNMNKGGYGRISVEQAIWYSSNIGVAKTILKGYSDNPTKFVEGLYRIGMNAD
EECCEECCCCCCCCCCCEEEHHHEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LRLEIPGAGRAKIRRPDDTTRYWSKTTLPWMSFGYETQVPPINTLAFFNAIANNGKMVRP
EEEECCCCCCCEEECCCCCHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEECH
MFTKEILHNGKTVQSFSTEVINSSICSDHTLALIKDMLLGVVEKGTGKAVHSDIVRIAGK
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
TGTAQIATGGVYRTSGHQVSFCGYFPADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIA
CCCEEEEECCEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
EKIYASHMSFDVRDMERDSMAVMVPRVKGGDLRAVEEVLDELDIKADTDSLETKWVVASA
HHHHHHHCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEC
EQEENKVKLSDLTIREGLVPRVVGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRV
CCCCCCEEEEEEEHHCCCCHHHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCC
SKGQTVLLTLK
CCCCEEEEEEC
>Mature Secondary Structure 
SEENEPKEIEPKGSRILFCYFVVVLLLGLVAVGILFRAFDTAFVERDKWMKVAESQKRP
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NRLVLPGRGNIYSSDGKLMATSVPRYYMYIDFKADAYTPAKGAKYNWLDTFKTSKKDGVD
CEEEECCCCCEECCCCCEEEEECCEEEEEEEEECCCCCCCCCCCCCCHHHHCCCCCCCHH
SLAFYLSRKLKDRTPAGYKAYLLKGLSGKSRQFPIYAGKVSYSDLKEIRKFPFLRLGRYK
HHHHHHHHHHHCCCCCCHHHHHEECCCCCCCCCCEEECCCCHHHHHHHHHCCCEEECCCC
SGFYTKEMVQRQKPFGTLASRTIGDIYGEIEEGGTTKGKNGLELQYDSLLRGQAGLSSVR
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHCCHHHHHHHH
RVGGGWTNVIEVDPVDGMDIRTTIDINIQDITEKSLVDKLKAIDAESGTAVVMEVETGEI
HHCCCCCCEEEECCCCCCEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCE
KAITNMGRIREGVYGETKNHAVADEIEPGSTFKVASIMVALEDGLCNPGDTVDVGNGIYM
EEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHEEEEHHCCCCCCCCEEECCCCEEE
YKGARMTDHNMNKGGYGRISVEQAIWYSSNIGVAKTILKGYSDNPTKFVEGLYRIGMNAD
EECCEECCCCCCCCCCCEEEHHHEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCC
LRLEIPGAGRAKIRRPDDTTRYWSKTTLPWMSFGYETQVPPINTLAFFNAIANNGKMVRP
EEEECCCCCCCEEECCCCCHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCCEECH
MFTKEILHNGKTVQSFSTEVINSSICSDHTLALIKDMLLGVVEKGTGKAVHSDIVRIAGK
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
TGTAQIATGGVYRTSGHQVSFCGYFPADHPKYSCIVVIRRPRIGYPSGGTMSGGVVRAIA
CCCEEEEECCEEECCCCEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
EKIYASHMSFDVRDMERDSMAVMVPRVKGGDLRAVEEVLDELDIKADTDSLETKWVVASA
HHHHHHHCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEC
EQEENKVKLSDLTIREGLVPRVVGMGAKDAVFLLEQAGLRVSLSGVGRVVSQSIQPGQRV
CCCCCCEEEEEEEHHCCCCHHHHCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHCCCCCCC
SKGQTVLLTLK
CCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]