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The map label for this gene is phoR [H]

Identifier: 150009042

GI number: 150009042

Start: 2867565

End: 2868722

Strand: Reverse

Name: phoR [H]

Synonym: BDI_2438

Alternate gene names: 150009042

Gene position: 2868722-2867565 (Counterclockwise)

Preceding gene: 150009043

Following gene: 150009041

Centisome position: 59.62

GC content: 42.57

Gene sequence:

>1158_bases
ATGAGCAGCATATATGATTCTCGTCAAAGATGGAAATTAGGCTTTATTTTTGCCGCTGTATTGATCGCTATGGCTTCTGT
GGTAGTCTCGGATCTCTTGATTAAAGATCTGGCCCGAGAAGAGCGTCAGAAGATCGAGGTTTGGAGTGAGGCAACCCGGG
TCATGACCAGTGAGAATCCAAGCCTTAATATGAATCTTATCCTAAAAATCATCCAAGGGAATACTTCTATTCCTGTTATA
TTATGCAGCGAGACGGATAGCGTGGTTTCTTACAATAATATAGAGATTCCGGAAAAGAATGTAGCGCAGTTCATGACGAA
TAAGGTTAAGGAACTGAGAACCAAAAATCCTCCGATCGTAATTGACATGGAGGATGGTACTTACCAATATTTATATTACG
ATGATTCGATTATCTTAAAGCGACTGCTTGTTTATCCCTATGCGCAATTATCAGTTGTATTTGTTTTTATATTAATCGCT
TTTTTAGCCTTGGCTAGTACAAAGAAGGCAGAACAGAATAAAGTGTGGGTGGGGTTATCGAAAGAGACGGCTCACCAATT
AGGAACGCCTATATCCTCGCTAATCGCTTGGGTTGAATATTTGCGAACGAAAGATATAGATCCTTCTCTATTGACAGAGA
TGGATAAGGATGTGAAACGCTTACAAACGATAGCGGAGCGTTTCTCTAAAATCGGTTCAGATCCAGATCCGGTTCCGACA
AATATCGTGGAATCCATCCGTGCGGCTTTGGGATATATGGAGACCCGTATTTCCTCGAAGGTGAAAATTAATACGTGTTT
GCCGGAGCGGCCGATATTGGTCTTAATGAATGATTCCCTGTTCGCTTGGGTAATCGAGAACCTGACGAAAAATGCGGTGG
ACGCCATGGAGGGGCAGGGTGAGATTTCGCTAAAAGTAGAGGAAAGAGAGAAGGTCGTGCTGATCGATTTGGCAGATACC
GGAAAAGGTATCCCAAAATCAAAATTCAAGACGGTTTTCAATCCGGGGTATACGACCAAGAAACGTGGCTGGGGATTAGG
CTTGTCCTTGGTAAAGCGCATTATCGAGTCCTTCCAAGGAGGAAAGATTTTCGTGAAGAGTTCGGAGCTAGGGAAAGGGA
CGACTTTTCGTATAAAATTGAAGAAATATAAGGGTTAA

Upstream 100 bases:

>100_bases
CGTCTCTACAACTGGGTGAGATTTCATTGTTTGCTGAATCGGGAACAATAAAGTTCGTATCTTGCCGTTATATTAAGAAT
TCACCGAATGATTCTGATTT

Downstream 100 bases:

>100_bases
ATCGTATTATAGGAAAAAATAAGCATAAAGGTATTGTTTTTGTATTTAGTTTTTTCGTACCTTTGCAAGGTTTTTACACT
AAAAGGCTTTGGGGAAATTT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MSSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQKIEVWSEATRVMTSENPSLNMNLILKIIQGNTSIPVI
LCSETDSVVSYNNIEIPEKNVAQFMTNKVKELRTKNPPIVIDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIA
FLALASTKKAEQNKVWVGLSKETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDVKRLQTIAERFSKIGSDPDPVPT
NIVESIRAALGYMETRISSKVKINTCLPERPILVLMNDSLFAWVIENLTKNAVDAMEGQGEISLKVEEREKVVLIDLADT
GKGIPKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESFQGGKIFVKSSELGKGTTFRIKLKKYKG

Sequences:

>Translated_385_residues
MSSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQKIEVWSEATRVMTSENPSLNMNLILKIIQGNTSIPVI
LCSETDSVVSYNNIEIPEKNVAQFMTNKVKELRTKNPPIVIDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIA
FLALASTKKAEQNKVWVGLSKETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDVKRLQTIAERFSKIGSDPDPVPT
NIVESIRAALGYMETRISSKVKINTCLPERPILVLMNDSLFAWVIENLTKNAVDAMEGQGEISLKVEEREKVVLIDLADT
GKGIPKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESFQGGKIFVKSSELGKGTTFRIKLKKYKG
>Mature_384_residues
SSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQKIEVWSEATRVMTSENPSLNMNLILKIIQGNTSIPVIL
CSETDSVVSYNNIEIPEKNVAQFMTNKVKELRTKNPPIVIDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIAF
LALASTKKAEQNKVWVGLSKETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDVKRLQTIAERFSKIGSDPDPVPTN
IVESIRAALGYMETRISSKVKINTCLPERPILVLMNDSLFAWVIENLTKNAVDAMEGQGEISLKVEEREKVVLIDLADTG
KGIPKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESFQGGKIFVKSSELGKGTTFRIKLKKYKG

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=215, Percent_Identity=29.7674418604651, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=221, Percent_Identity=28.9592760180996, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43370; Mature: 43239

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQKIEVWSEATRVMTSENP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLNMNLILKIIQGNTSIPVILCSETDSVVSYNNIEIPEKNVAQFMTNKVKELRTKNPPIV
CCCHHEEEEEEECCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
IDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIAFLALASTKKAEQNKVWVGLS
EEECCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
KETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDVKRLQTIAERFSKIGSDPDPVPT
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
NIVESIRAALGYMETRISSKVKINTCLPERPILVLMNDSLFAWVIENLTKNAVDAMEGQG
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
EISLKVEEREKVVLIDLADTGKGIPKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESFQG
CEEEEEECCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GKIFVKSSELGKGTTFRIKLKKYKG
CEEEEECCCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
SSIYDSRQRWKLGFIFAAVLIAMASVVVSDLLIKDLAREERQKIEVWSEATRVMTSENP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SLNMNLILKIIQGNTSIPVILCSETDSVVSYNNIEIPEKNVAQFMTNKVKELRTKNPPIV
CCCHHEEEEEEECCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
IDMEDGTYQYLYYDDSIILKRLLVYPYAQLSVVFVFILIAFLALASTKKAEQNKVWVGLS
EEECCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
KETAHQLGTPISSLIAWVEYLRTKDIDPSLLTEMDKDVKRLQTIAERFSKIGSDPDPVPT
HHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
NIVESIRAALGYMETRISSKVKINTCLPERPILVLMNDSLFAWVIENLTKNAVDAMEGQG
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCC
EISLKVEEREKVVLIDLADTGKGIPKSKFKTVFNPGYTTKKRGWGLGLSLVKRIIESFQG
CEEEEEECCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
GKIFVKSSELGKGTTFRIKLKKYKG
CEEEEECCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]