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The map label for this gene is mtnA [H]

Identifier: 150008885

GI number: 150008885

Start: 2669256

End: 2670293

Strand: Reverse

Name: mtnA [H]

Synonym: BDI_2280

Alternate gene names: 150008885

Gene position: 2670293-2669256 (Counterclockwise)

Preceding gene: 150008886

Following gene: 150008884

Centisome position: 55.5

GC content: 54.72

Gene sequence:

>1038_bases
ATGATACAAACTCTATCTGATTTAAAGACCGTGCGTTTCAACGAGCAAGCGGACGGTGTGATCATTTTGGACCAAACTCT
GCTGCCGGGTAAGGAAGCGTATCTGACCCTTACCACTGCCGAGGAGATATGGGACGCTATCTATAAATTAAAGGTACGTG
GAGCACCTGCTATCGGGGTAGCGGCCGCTTATGGTATCTATGTCTGCGCCCGTCGGATCGATACGGCGGAGAAATCCGTT
TTCGTGAATGAGTTTCGGAAGATCAAGGAGTATCTGGCCGGTTCCCGTCCGACAGCGGTGAATCTGGTGGCGGCGCTGAA
CCGGATGGAGCGGGTATTGGTCGCTCATCCAACCTTGTCTGTCCCGGAATGGAAAGAGCTATTATATAAGGAAGCGATCG
CGATCCGGGAGGAAGACGCCGCCGCTTGCCGGCAGATCGGCGAGAACTGTCTGGAGCTACTCCGTCCCGGGATGGGAATC
CTTACGCATTGTAACGCCGGACATCTGGCGGTCTCGGAGTATGGCACCGCTTTGGCGCCGATTTATCTGGGGCAGGAGAG
AGGTTATGGTTTCAAGGTCTTCGCCGACGAGACCCGTCCTTTGTTGCAAGGCGCCCGGCTCACGGCCTATGAGCTAAGCA
GGGCCGGCGTGGACGTGACGCTGATTTGCGATAATATGGCCTCCGTCGTCATGCGGAAAGGCTGGGTGCATGCCGTGGTC
GTAGGTTGCGACCGTGTAGCCGCCAATGGCGACGTGGCGAATAAGATCGGCACGTCTGGAGTGGCTATCTTGGCCCGGCA
TTACAAGATCCCCTTCTATGTATTAGGCCCGACATCCACCATCGATGGCTCGTGCCCGGACGGCGATTCCATTGTAATAG
AGGAACGTAACCCCGATGAGGTCACCGAGATGTGGTATTCAAGGCGTATGGCCCCGAAAGACGTGAAAGTCTACAACCCC
GCCTTCGACATTACTCCCCACGAGCTAATCACGGCTATAATTACGGAGAAAGGCATCTTTTATAAAAATAATCGCTGA

Upstream 100 bases:

>100_bases
CTACGGCAGGCCTTGTCGTAGGAGCGATAGCGGTTACCGCCGCAGGGGTGGCGATAGAAGCTACGCTGGGTCCCGTGAAC
TATTAATATATTCATATCGA

Downstream 100 bases:

>100_bases
AAGTTTTGCTAATCCCGAAACAATCAGTAATTTTGCCGCTCAATTTGAGGATATAAATAATTAAACAATATAACAATTTA
AATTATGATCGTAGTTCCAT

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGVAAAYGIYVCARRIDTAEKSV
FVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLSVPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGI
LTHCNAGHLAVSEYGTALAPIYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVV
VGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDEVTEMWYSRRMAPKDVKVYNP
AFDITPHELITAIITEKGIFYKNNR

Sequences:

>Translated_345_residues
MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGVAAAYGIYVCARRIDTAEKSV
FVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLSVPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGI
LTHCNAGHLAVSEYGTALAPIYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVV
VGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDEVTEMWYSRRMAPKDVKVYNP
AFDITPHELITAIITEKGIFYKNNR
>Mature_345_residues
MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGVAAAYGIYVCARRIDTAEKSV
FVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLSVPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGI
LTHCNAGHLAVSEYGTALAPIYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVV
VGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDEVTEMWYSRRMAPKDVKVYNP
AFDITPHELITAIITEKGIFYKNNR

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=351, Percent_Identity=39.8860398860399, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI23943880, Length=335, Percent_Identity=37.0149253731343, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI7657058, Length=152, Percent_Identity=30.2631578947368, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557462, Length=342, Percent_Identity=31.8713450292398, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17557123, Length=181, Percent_Identity=29.2817679558011, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325375, Length=389, Percent_Identity=34.9614395886889, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322878, Length=284, Percent_Identity=26.056338028169, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357667, Length=336, Percent_Identity=40.7738095238095, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24651647, Length=336, Percent_Identity=40.7738095238095, Blast_Score=235, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38037; Mature: 38037

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGV
CCCCHHHHHHEEECCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHEEECCCCCHHH
AAAYGIYVCARRIDTAEKSVFVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCC
VPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGILTHCNAGHLAVSEYGTALAP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHCCCEEEE
IYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVV
EEEECCCCCEEEEEECCCHHHHCCCCCEEEEHHHCCCEEEEEECHHHHHHHHCCCCEEEE
VGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDE
EECCHHCCCCCHHHHCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEECCCCHH
VTEMWYSRRMAPKDVKVYNPAFDITPHELITAIITEKGIFYKNNR
HHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MIQTLSDLKTVRFNEQADGVIILDQTLLPGKEAYLTLTTAEEIWDAIYKLKVRGAPAIGV
CCCCHHHHHHEEECCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHEEECCCCCHHH
AAAYGIYVCARRIDTAEKSVFVNEFRKIKEYLAGSRPTAVNLVAALNRMERVLVAHPTLS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCC
VPEWKELLYKEAIAIREEDAAACRQIGENCLELLRPGMGILTHCNAGHLAVSEYGTALAP
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHCCCEEEE
IYLGQERGYGFKVFADETRPLLQGARLTAYELSRAGVDVTLICDNMASVVMRKGWVHAVV
EEEECCCCCEEEEEECCCHHHHCCCCCEEEEHHHCCCEEEEEECHHHHHHHHCCCCEEEE
VGCDRVAANGDVANKIGTSGVAILARHYKIPFYVLGPTSTIDGSCPDGDSIVIEERNPDE
EECCHHCCCCCHHHHCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEECCCCHH
VTEMWYSRRMAPKDVKVYNPAFDITPHELITAIITEKGIFYKNNR
HHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA