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The map label for this gene is pyrF

Identifier: 150008713

GI number: 150008713

Start: 2487332

End: 2488174

Strand: Direct

Name: pyrF

Synonym: BDI_2103

Alternate gene names: 150008713

Gene position: 2487332-2488174 (Clockwise)

Preceding gene: 150008712

Following gene: 150008714

Centisome position: 51.7

GC content: 45.31

Gene sequence:

>843_bases
ATGAACAAACAACAGCTATTCGAGAATATTAAAAAGAAACAATCCTTCCTTTGTGTCGGATTAGATACAGATATAAAAAA
GATCCCGCAACATCTATTGTCGGAAGAAGATCCTATTTTCGCATTCAATAAAGCGATCATCGACGCTACCGCCGATTATT
GTGTCGCTTACAAGCCGAATCTGGCTTTTTACGAGAGCCTCGGCACAAAGGGTATGATGGCTTTTGAGAAGACTGTGGCT
TACTTACGGGAGAATTATCCCGATCAATTTATCATCGCCGACGCGAAACGTGGTGATATCGGAAATACCTCCGAGATGTA
TGCCCGTTCTTTCTTCGATCATATCAAGGTAGATGCCGTAACGGTCGCTCCCTATATGGGCGAGGATAGCGTAAAACCAT
TCTTGATCTACCCGGAGGCTTGGGTAATCTTATTGGCCTTGACCTCCAATAAAGGCTCACATGATTTTCAAATGACGGAA
GACGCAAATGGTGAACGTCTTTTCGAGAAAGTACTAAAGAAATCGCAAGAATGGGCTAACGATGAGCAAATGATGTATGT
AGTGGGCGCTACCCAAGGCAAGATGTTCCTTGATATCCGTAAACAGGCCCCGAATCATTTCTTGTTAGTTCCGGGCGTAG
GCGCTCAAGGTGGAAGCTTGGCGGAAGTAGCTCAATACGGGATGAACGACCAATGCGGTCTTTTGGTAAATTCTTCCCGT
GCGATTATTTACGCAGATAAGACGGAGGCTTTCGCCAACGTAGCCCGTGAGGCGGCACATGCCGTACAGAAAGAAATGGC
CGGTTATCTACATGATAAGGGAATTATTCCCTGCAAAGCATAG

Upstream 100 bases:

>100_bases
TTCAAGATTGCTTGGATCACCTGATCGTAGCGGAGAACGCTGAGCGACTGAAAGAGTCTGAATTGTAAACACATCCAATC
ATTTCATACTGAATAAGAAA

Downstream 100 bases:

>100_bases
GCTATATAAAGAATTTTCACCATTTTTGCAAACTAACTGTCTATAAACAGCGGACAGTCAACGAAGATACATATATAATT
GAATAAGTAATGGAGTTTTC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNKAIIDATADYCVAYKPNLAFYESLGTKGMMAFEKTVA
YLRENYPDQFIIADAKRGDIGNTSEMYARSFFDHIKVDAVTVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTE
DANGERLFEKVLKKSQEWANDEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGGSLAEVAQYGMNDQCGLLVNSSR
AIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGIIPCKA

Sequences:

>Translated_280_residues
MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNKAIIDATADYCVAYKPNLAFYESLGTKGMMAFEKTVA
YLRENYPDQFIIADAKRGDIGNTSEMYARSFFDHIKVDAVTVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTE
DANGERLFEKVLKKSQEWANDEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGGSLAEVAQYGMNDQCGLLVNSSR
AIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGIIPCKA
>Mature_280_residues
MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNKAIIDATADYCVAYKPNLAFYESLGTKGMMAFEKTVA
YLRENYPDQFIIADAKRGDIGNTSEMYARSFFDHIKVDAVTVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTE
DANGERLFEKVLKKSQEWANDEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGGSLAEVAQYGMNDQCGLLVNSSR
AIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGIIPCKA

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_PARD8 (A6LDS0)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001303456.1
- ProteinModelPortal:   A6LDS0
- SMR:   A6LDS0
- STRING:   A6LDS0
- GeneID:   5307252
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_2103
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   CLSK823836
- BioCyc:   PDIS435591:BDI_2103-MONOMER
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 31263; Mature: 31263

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 96-96

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNKAIIDATADYCVAYKPN
CCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEECCC
LAFYESLGTKGMMAFEKTVAYLRENYPDQFIIADAKRGDIGNTSEMYARSFFDHIKVDAV
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHEEEEE
TVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTEDANGERLFEKVLKKSQEWAN
EECCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHCCC
DEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGGSLAEVAQYGMNDQCGLLVNSSR
CCEEEEEEECCCCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCEEEECCE
AIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGIIPCKA
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNKQQLFENIKKKQSFLCVGLDTDIKKIPQHLLSEEDPIFAFNKAIIDATADYCVAYKPN
CCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCEEEEECCC
LAFYESLGTKGMMAFEKTVAYLRENYPDQFIIADAKRGDIGNTSEMYARSFFDHIKVDAV
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHEEEEE
TVAPYMGEDSVKPFLIYPEAWVILLALTSNKGSHDFQMTEDANGERLFEKVLKKSQEWAN
EECCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHCCC
DEQMMYVVGATQGKMFLDIRKQAPNHFLLVPGVGAQGGSLAEVAQYGMNDQCGLLVNSSR
CCEEEEEEECCCCEEEEEEECCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCEEEECCE
AIIYADKTEAFANVAREAAHAVQKEMAGYLHDKGIIPCKA
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA