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The map label for this gene is purM [H]

Identifier: 150008711

GI number: 150008711

Start: 2485014

End: 2486180

Strand: Direct

Name: purM [H]

Synonym: BDI_2101

Alternate gene names: 150008711

Gene position: 2485014-2486180 (Clockwise)

Preceding gene: 150008710

Following gene: 150008712

Centisome position: 51.65

GC content: 47.22

Gene sequence:

>1167_bases
ATGAGTGATCAACGTTATAACCTGCGAGGCGTTTCCGCTTCAAAAGAAGATGTTCACAATGCGATAAAGAACATCGATAA
GGGAATTTTTCCGAAAGCGTTCTGTAAGATCATCCCCGATATCTTAGGCGGTGATCCTGAATATTGTAATATTATGCACG
CGGATGGCGCCGGTACCAAATCGTCCTTGGCGTATATGTACTGGAAAGAGACCGGAGATCTTTCGGTGTGGAAAGGTATC
GCCCAAGACGCTCTTATCATGAATATCGACGACCTGCTCTGCGTAGGTGCCGTAGACAATATCTTGGTCTCTTCTACAAT
TGGACGTAACAAGCTGTTGGTTCCGGGCGAGGTGATCTCGGCGATCATCAATGGAACAGATGAGTTGCTGGCAGAGTTAC
GTGAGATGGGCGTTGGTTGCTACGCGACAGGTGGCGAGACCGCAGACGTTGGCGACTTAGTTCGTACCATCATCGTAGAT
AGTACGGTCACTTGCCGCATGAAACGTTCGGACGTAATCGATAATAAGAATATCCAAGGAGGAGACGTGATCGTAGGTCT
GGCATCTTCCGGACAAGCCACTTACGAGAAAGAATACAATGGAGGTATGGGTAGCAACGGCTTGACCTCTGCCCGCCATG
ATGTTTTCTCTAAGTATTTAGCGAAAAAATATCCGGAAAGCTACGATGCCGCCGTTCCCAAAGAATTGGTTTACTCCGGA
GGATTGAAACTTACGGATAAGATCGAGGAATTAGGGATCGATGCCGGAAAGATGGTGCTTTCGCCTACACGTACCTATGC
GCCGGTAATTAAGGTATTGCTTGATAAACTACGCTCTCAAATCCATGGTATGGTACATTGTTCGGGAGGGGCCCAGACAA
AAGTCATGCATTTCGTAGAGAACAAGCGTGTAACTAAGGACAATCTCTTCCCTATCCCACCGTTATTCCGCACGATTCAG
GAGCAGAGCGGTACGGACTGGAGCGAGATGTACAAGGTATTCAATATGGGACACCGGATGGAGATATACATCGCTCCCGA
GCATGCGGAAGAAGTAATCGGCATCTCAAAAAGCTTTGGTATTGATGCGCAAATCGTGGGCTTCGTAGAGGAAGCTGATA
AAAATGAATTGATTATCGAAAGCGAGAAAGGTCGCTTCACCTATTAA

Upstream 100 bases:

>100_bases
AAAAAAGACAAAGATTACATCCCGGAGGAAGGAGATGTCTTAAAACTTAGATAAGTAACATAAAAAAGTATTACCTTTGC
GGTTCAAATAATATAGTACA

Downstream 100 bases:

>100_bases
TAAAGATAAATGGCCGAAAATAGTTTACTTGGTAAATTAGACGGATTAGTGAGCCGTTTCGAGGAAGTCGGTACCCTTAT
TACCGACCCGGCGGTGATCG

Product: putative phosphoribosylformylglycinamidine cyclo-ligase

Products: NA

Alternate protein names: AIR synthase; AIRS; Phosphoribosyl-aminoimidazole synthetase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGI
AQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLVPGEVISAIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVD
STVTCRMKRSDVIDNKNIQGGDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSKYLAKKYPESYDAAVPKELVYSG
GLKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDKLRSQIHGMVHCSGGAQTKVMHFVENKRVTKDNLFPIPPLFRTIQ
EQSGTDWSEMYKVFNMGHRMEIYIAPEHAEEVIGISKSFGIDAQIVGFVEEADKNELIIESEKGRFTY

Sequences:

>Translated_388_residues
MSDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGI
AQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLVPGEVISAIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVD
STVTCRMKRSDVIDNKNIQGGDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSKYLAKKYPESYDAAVPKELVYSG
GLKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDKLRSQIHGMVHCSGGAQTKVMHFVENKRVTKDNLFPIPPLFRTIQ
EQSGTDWSEMYKVFNMGHRMEIYIAPEHAEEVIGISKSFGIDAQIVGFVEEADKNELIIESEKGRFTY
>Mature_387_residues
SDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTKSSLAYMYWKETGDLSVWKGIA
QDALIMNIDDLLCVGAVDNILVSSTIGRNKLLVPGEVISAIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVDS
TVTCRMKRSDVIDNKNIQGGDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSKYLAKKYPESYDAAVPKELVYSGG
LKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDKLRSQIHGMVHCSGGAQTKVMHFVENKRVTKDNLFPIPPLFRTIQE
QSGTDWSEMYKVFNMGHRMEIYIAPEHAEEVIGISKSFGIDAQIVGFVEEADKNELIIESEKGRFTY

Specific function: De novo purine biosynthesis; fifth step. [C]

COG id: COG0150

COG function: function code F; Phosphoribosylaminoimidazole (AIR) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR004733
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.3.1 [H]

Molecular weight: Translated: 42493; Mature: 42362

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTK
CCCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLVPGEVIS
CCEEEEEEECCCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHH
AIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVDSTVTCRMKRSDVIDNKNIQG
HHHCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
GDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSKYLAKKYPESYDAAVPKELVYSG
CCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
GLKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDKLRSQIHGMVHCSGGAQTKVMHFVE
CCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHH
NKRVTKDNLFPIPPLFRTIQEQSGTDWSEMYKVFNMGHRMEIYIAPEHAEEVIGISKSFG
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCC
IDAQIVGFVEEADKNELIIESEKGRFTY
CCHHEEEHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SDQRYNLRGVSASKEDVHNAIKNIDKGIFPKAFCKIIPDILGGDPEYCNIMHADGAGTK
CCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
SSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGAVDNILVSSTIGRNKLLVPGEVIS
CCEEEEEEECCCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHH
AIINGTDELLAELREMGVGCYATGGETADVGDLVRTIIVDSTVTCRMKRSDVIDNKNIQG
HHHCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC
GDVIVGLASSGQATYEKEYNGGMGSNGLTSARHDVFSKYLAKKYPESYDAAVPKELVYSG
CCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
GLKLTDKIEELGIDAGKMVLSPTRTYAPVIKVLLDKLRSQIHGMVHCSGGAQTKVMHFVE
CCCHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHH
NKRVTKDNLFPIPPLFRTIQEQSGTDWSEMYKVFNMGHRMEIYIAPEHAEEVIGISKSFG
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHCCCCCCC
IDAQIVGFVEEADKNELIIESEKGRFTY
CCHHEEEHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA