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The map label for this gene is pgcA [H]

Identifier: 150008707

GI number: 150008707

Start: 2480840

End: 2482588

Strand: Direct

Name: pgcA [H]

Synonym: BDI_2097

Alternate gene names: 150008707

Gene position: 2480840-2482588 (Clockwise)

Preceding gene: 150008706

Following gene: 150008709

Centisome position: 51.56

GC content: 43.85

Gene sequence:

>1749_bases
ATGGAAAACAACGACTTATTAGAAATGGTAAGAAGTAAGGCACAAGGATGGCTTACGAAAAGTTATGATGCGGAAACTCG
TGCTCAAGTTCAAGCGTTACTTGACAACGAAGATCCTACTGAGTTAATCGAGTGTTTTTATAAAGACCTAGAATTCGGAA
CAGGTGGATTGCGCGGAATCATGGGGGTAGGTTCAAATCGTATGAATATATATACAGTTGGCGCAGCTACCCAAGGTTTA
TCCAACTATCTGAAAAAGGAATTTGCGGATTTAGAACAGATAAAGGTTGTCATCGGCCACGATTGCCGTAACAACAGCCG
TAAGTTCGCGGAAATATCAGCCGATATCTTCTCCGCTAACGGCATCAAGGTTTATTTATTCGAAGACCTGCGTCCGACTC
CGGAAATGTCATTCGCTATCCGTAAACTGGGATGCCAGAGCGGTATCATCTTGACGGCTTCTCACAATCCGAAAGAATAC
AACGGATACAAGGCTTATTGGGATGATGGCGCACAAATGATCGCCCCGCACGATAAGAATACGATCGCCGAGGTTAACAA
GATCCGTAACGCTAGCGAGATTAAATTCAAAGGAAATAAAGAATTGATCGAGATCATCGGACAAGCGATCGATGATGAAT
ATATCAAGGAATTAACAACGATTTCTTTGTCTCCGGAGGCTATTTCCCGCCATAAGGATATGAAGATCGTGTATACTCCA
ATTCACGGAACAGGTGTTAAATTGGTTCCTGCCGCTTTGAAAGCTTACGGATTCACGAACATTATCCATGTACCGGAACA
AGATGTTGTTAGCGGTGATTTCCCGACGGTTATCTCTCCGAACCCGGAAGAGCCGGCTGCTTTAGCTATGGCTGTAGAGA
AAGCAAAAGAGACTGACGCTGAATTGGTAATGGCTTCCGATCCGGACGCAGACCGTGTAGGTGCCGCCGTTAAGAATAAC
GAAGGCGAATGGGTACTTTTGAATGGTAACCAAACCGCTTTGATGTTCGTTTACTATTTAATCACTCGCTGGAAAGAGTT
AGGTAAGATCAATGGTAAAGAATATATCGTAAAGACAATCGTTACGACAGAGACGATCAAGACGATCGCCGAGCGTAATG
GCGTAGAAATGTACGATGTTTATACAGGCTTCAAATGGATCGCTAACGTTATGCGTGAGAACGAAAGCAAGAAAAACTAT
ATCGGTGGTGGCGAGGAAAGCTACGGATTCCTTTGCGAGGACTTCGTTCGCGATAAAGACGCTGTTTCCGCTTGCGTTAT
CTTAGCCGAGATCGCAGCTTGGGCAAAAGATCAAGGTTTGAGTTTGTATCAATTGCTTCAGAAGATTTACGTGGAATACG
GCTTCTCTAAGGAGAAAGGTATCTCTGTCGTGAAGAAAGGCAAGAGTGGAGCGGAGGAGATCGAGGCTATGATGAAAAAG
TTCCGTGAGAACCCGTTGACAGAGATCGCAGGCTCTAAGGTAACTTATTTCTACGATTACTCTACATTGAAAGGTAAGGA
CTATGCAGAGAACGAAACCGTTACATTAGATATGCCTACTACCTCTAATGTGCTTCAATACTTCACGGAAGATAATACAA
AAGTATCTATCCGTCCTTCCGGAACAGAACCGAAGATCAAATTCTATTGCGAGGTTCACTCCAAGGTAAAGAGTATCGAT
GAATTGCCGGAGGCAGAGAAAGCGGCAGAAGAAAAGATCAATCAGATCAAGGCTTCTTTAGGGATCTAA

Upstream 100 bases:

>100_bases
TCCTTTGATTGCTTTACTTTAAGAAATTCGTATATTTGTTTCTTGTATATTTATCGTATTGAGTAGATTGCTCAACAATA
AACACAATAATATTATAAAC

Downstream 100 bases:

>100_bases
TCGAACTTAATTATTACATATAGAGGCAAGGGCGAGAATCGTTCTTGCCTCTTTTTATTCTATCAGATCAAATCAGACTT
ACTGAAACAAAACGGCAACA

Product: phosphoglucomutase phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIECFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKEFADLEQIKVVIGHDCRNNSRKFAEISADIFSANGIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEY
NGYKAYWDDGAQMIAPHDKNTIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKELTTISLSPEAISRHKDMKIVYTP
IHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPTVISPNPEEPAALAMAVEKAKETDAELVMASDPDADRVGAAVKNN
EGEWVLLNGNQTALMFVYYLITRWKELGKINGKEYIVKTIVTTETIKTIAERNGVEMYDVYTGFKWIANVMRENESKKNY
IGGGEESYGFLCEDFVRDKDAVSACVILAEIAAWAKDQGLSLYQLLQKIYVEYGFSKEKGISVVKKGKSGAEEIEAMMKK
FRENPLTEIAGSKVTYFYDYSTLKGKDYAENETVTLDMPTTSNVLQYFTEDNTKVSIRPSGTEPKIKFYCEVHSKVKSID
ELPEAEKAAEEKINQIKASLGI

Sequences:

>Translated_582_residues
MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIECFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKEFADLEQIKVVIGHDCRNNSRKFAEISADIFSANGIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEY
NGYKAYWDDGAQMIAPHDKNTIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKELTTISLSPEAISRHKDMKIVYTP
IHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPTVISPNPEEPAALAMAVEKAKETDAELVMASDPDADRVGAAVKNN
EGEWVLLNGNQTALMFVYYLITRWKELGKINGKEYIVKTIVTTETIKTIAERNGVEMYDVYTGFKWIANVMRENESKKNY
IGGGEESYGFLCEDFVRDKDAVSACVILAEIAAWAKDQGLSLYQLLQKIYVEYGFSKEKGISVVKKGKSGAEEIEAMMKK
FRENPLTEIAGSKVTYFYDYSTLKGKDYAENETVTLDMPTTSNVLQYFTEDNTKVSIRPSGTEPKIKFYCEVHSKVKSID
ELPEAEKAAEEKINQIKASLGI
>Mature_582_residues
MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIECFYKDLEFGTGGLRGIMGVGSNRMNIYTVGAATQGL
SNYLKKEFADLEQIKVVIGHDCRNNSRKFAEISADIFSANGIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEY
NGYKAYWDDGAQMIAPHDKNTIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKELTTISLSPEAISRHKDMKIVYTP
IHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPTVISPNPEEPAALAMAVEKAKETDAELVMASDPDADRVGAAVKNN
EGEWVLLNGNQTALMFVYYLITRWKELGKINGKEYIVKTIVTTETIKTIAERNGVEMYDVYTGFKWIANVMRENESKKNY
IGGGEESYGFLCEDFVRDKDAVSACVILAEIAAWAKDQGLSLYQLLQKIYVEYGFSKEKGISVVKKGKSGAEEIEAMMKK
FRENPLTEIAGSKVTYFYDYSTLKGKDYAENETVTLDMPTTSNVLQYFTEDNTKVSIRPSGTEPKIKFYCEVHSKVKSID
ELPEAEKAAEEKINQIKASLGI

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=586, Percent_Identity=35.1535836177474, Blast_Score=334, Evalue=2e-91,
Organism=Homo sapiens, GI31377548, Length=561, Percent_Identity=34.0463458110517, Blast_Score=294, Evalue=1e-79,
Organism=Homo sapiens, GI21361621, Length=564, Percent_Identity=24.822695035461, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1786904, Length=470, Percent_Identity=24.8936170212766, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71993870, Length=549, Percent_Identity=33.6976320582878, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71993878, Length=315, Percent_Identity=36.8253968253968, Blast_Score=195, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6323934, Length=570, Percent_Identity=31.5789473684211, Blast_Score=251, Evalue=2e-67,
Organism=Drosophila melanogaster, GI20129809, Length=567, Percent_Identity=31.5696649029982, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24651977, Length=490, Percent_Identity=32.6530612244898, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24653722, Length=593, Percent_Identity=28.3305227655987, Blast_Score=215, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64981; Mature: 64981

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIECFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLKKEFADLEQIKVVIGHDCRNNSRKFAEISADIFSAN
HCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCC
GIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEYNGYKAYWDDGAQMIAPHDKN
CEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCH
TIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKELTTISLSPEAISRHKDMKIVYTP
HHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
IHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPTVISPNPEEPAALAMAVEKAKETDA
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ELVMASDPDADRVGAAVKNNEGEWVLLNGNQTALMFVYYLITRWKELGKINGKEYIVKTI
EEEEECCCCHHHHCCCEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
VTTETIKTIAERNGVEMYDVYTGFKWIANVMRENESKKNYIGGGEESYGFLCEDFVRDKD
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHH
AVSACVILAEIAAWAKDQGLSLYQLLQKIYVEYGFSKEKGISVVKKGKSGAEEIEAMMKK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHH
FRENPLTEIAGSKVTYFYDYSTLKGKDYAENETVTLDMPTTSNVLQYFTEDNTKVSIRPS
HHCCCHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEC
GTEPKIKFYCEVHSKVKSIDELPEAEKAAEEKINQIKASLGI
CCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENNDLLEMVRSKAQGWLTKSYDAETRAQVQALLDNEDPTELIECFYKDLEFGTGGLRGI
CCCHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
MGVGSNRMNIYTVGAATQGLSNYLKKEFADLEQIKVVIGHDCRNNSRKFAEISADIFSAN
HCCCCCCEEEEEECCHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHHHHHCCCC
GIKVYLFEDLRPTPEMSFAIRKLGCQSGIILTASHNPKEYNGYKAYWDDGAQMIAPHDKN
CEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCCCH
TIAEVNKIRNASEIKFKGNKELIEIIGQAIDDEYIKELTTISLSPEAISRHKDMKIVYTP
HHHHHHHHCCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCEEEEEE
IHGTGVKLVPAALKAYGFTNIIHVPEQDVVSGDFPTVISPNPEEPAALAMAVEKAKETDA
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
ELVMASDPDADRVGAAVKNNEGEWVLLNGNQTALMFVYYLITRWKELGKINGKEYIVKTI
EEEEECCCCHHHHCCCEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEHHH
VTTETIKTIAERNGVEMYDVYTGFKWIANVMRENESKKNYIGGGEESYGFLCEDFVRDKD
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCHH
AVSACVILAEIAAWAKDQGLSLYQLLQKIYVEYGFSKEKGISVVKKGKSGAEEIEAMMKK
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHH
FRENPLTEIAGSKVTYFYDYSTLKGKDYAENETVTLDMPTTSNVLQYFTEDNTKVSIRPS
HHCCCHHHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEEC
GTEPKIKFYCEVHSKVKSIDELPEAEKAAEEKINQIKASLGI
CCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]