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The map label for this gene is pdxH [H]

Identifier: 150008705

GI number: 150008705

Start: 2478285

End: 2478929

Strand: Direct

Name: pdxH [H]

Synonym: BDI_2095

Alternate gene names: 150008705

Gene position: 2478285-2478929 (Clockwise)

Preceding gene: 150008704

Following gene: 150008706

Centisome position: 51.51

GC content: 47.6

Gene sequence:

>645_bases
ATGGAAATAAATCTCGCCTCAATCCGGCAAGAATACACAAAAGGAGGATTAAGGGAAAGTGAACTTCCGGATAACCCATT
CTTGCTTTTCAGTCAATGGTTACAAGAGGCTATAGACAGCAAAGTAGATGAACCCACGGCCATGCTAGTAGGGACCGTAT
CTCCAGAAGGCAAACCTTCCACCCGTACCGTCTTATTAAAGGACCTGCATGATGATAAGTTTATTTTCTACTCCAACTAC
GAAAGCCGAAAAGGCAGGCAACTGGCACAAAACCCGGCAATCTCTCTTTCGTTTGTATGGCATCAATTAGAAAGGCAGGT
ACATATCGAAGGTACGGCTGAAAAAGTCCCCCCGGATGAATCGGATCAATATTTCAAAAAACGCCCGTATAAAAGCCGGA
TCGGAGCTCGTATATCCCCACAAAGTCAACCCATCGGCAACCGTGTGCAACTTATACGAGCTTTCATTAGAGAGGCAGCT
CGTTGGATTGGAAAAGAAGTGGAGCGTCCGGCTCACTGGGGCGGGTATGCCGTCATTCCCGAACGTATCGAGTTCTGGCA
AGGTAGGCCCAACCGACTTCATGATCGCATAGTATATACCCTTCAACCGGACGGCCATTGGAAAAAAGAAAGGCTCGCCC
CATGA

Upstream 100 bases:

>100_bases
AATCAAACGCTGAAAAGAAAACCTTGAAACCTTTTTTTCGATCTCTTGTTATCCTATTAAAGAAGAAAAGCTATGTAGTC
AACAAGCAAACAGAACACAT

Downstream 100 bases:

>100_bases
AATCAGGTACAAGTCCGATACCAAAGGATAAGAGATAGATAATTCATCGAAAACGATTATCTTTGTCTGTCAAAATACGT
AATACCTATGAATATTAGAT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDEPTAMLVGTVSPEGKPSTRTVLLKDLHDDKFIFYSNY
ESRKGRQLAQNPAISLSFVWHQLERQVHIEGTAEKVPPDESDQYFKKRPYKSRIGARISPQSQPIGNRVQLIRAFIREAA
RWIGKEVERPAHWGGYAVIPERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP

Sequences:

>Translated_214_residues
MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDEPTAMLVGTVSPEGKPSTRTVLLKDLHDDKFIFYSNY
ESRKGRQLAQNPAISLSFVWHQLERQVHIEGTAEKVPPDESDQYFKKRPYKSRIGARISPQSQPIGNRVQLIRAFIREAA
RWIGKEVERPAHWGGYAVIPERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP
>Mature_214_residues
MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDEPTAMLVGTVSPEGKPSTRTVLLKDLHDDKFIFYSNY
ESRKGRQLAQNPAISLSFVWHQLERQVHIEGTAEKVPPDESDQYFKKRPYKSRIGARISPQSQPIGNRVQLIRAFIREAA
RWIGKEVERPAHWGGYAVIPERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=39.5652173913043, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1787926, Length=210, Percent_Identity=46.6666666666667, Blast_Score=189, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17553712, Length=226, Percent_Identity=39.8230088495575, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=41.6267942583732, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45551845, Length=234, Percent_Identity=40.1709401709402, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24644901, Length=234, Percent_Identity=40.1709401709402, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24644903, Length=188, Percent_Identity=23.936170212766, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640564, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24858; Mature: 24858

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS01064 PYRIDOX_OXIDASE ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDEPTAMLVGTVSPEGKPS
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TRTVLLKDLHDDKFIFYSNYESRKGRQLAQNPAISLSFVWHQLERQVHIEGTAEKVPPDE
HHEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCCC
SDQYFKKRPYKSRIGARISPQSQPIGNRVQLIRAFIREAARWIGKEVERPAHWGGYAVIP
CHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECH
ERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEINLASIRQEYTKGGLRESELPDNPFLLFSQWLQEAIDSKVDEPTAMLVGTVSPEGKPS
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
TRTVLLKDLHDDKFIFYSNYESRKGRQLAQNPAISLSFVWHQLERQVHIEGTAEKVPPDE
HHEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHEEEECCCCCCCCCCC
SDQYFKKRPYKSRIGARISPQSQPIGNRVQLIRAFIREAARWIGKEVERPAHWGGYAVIP
CHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECH
ERIEFWQGRPNRLHDRIVYTLQPDGHWKKERLAP
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA