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The map label for this gene is ung1 [H]

Identifier: 150008646

GI number: 150008646

Start: 2400532

End: 2401194

Strand: Direct

Name: ung1 [H]

Synonym: BDI_2034

Alternate gene names: 150008646

Gene position: 2400532-2401194 (Clockwise)

Preceding gene: 150008635

Following gene: 150008647

Centisome position: 49.89

GC content: 46.46

Gene sequence:

>663_bases
ATGAATGTTAGAATAGATGAAAGTTGGAGAAAACGTCTGCAAGAAGAATTTGACAAGCCTTATTTCGAGCAATTGGTGAC
ATTTGTCAAAAACGAATATAAGCAAGCGCACGTACTTCCTCCCGGGCCCCAGATATTCCATATATTTAACGCATGCCCGT
TTGAGAAGGTAAAAGTCGTTATCTTGGGACAAGACCCCTATCCAAATCCGGGGCAATACTATGGGGTCTGCTTCTCGGTA
CCCGATGGCGTGGCGATTCCCGGTTCCTTGATGAATATATTCAAAGAAATCTACGATGATCTTGGGAAACCGATTCCTTC
CTCCGGGAATTTGGATCGTTGGGTAAGCCAAGGCGTATTTCCGATGAATTCCGTCCTCACGGTCCGTGCCCACCAAACAG
GCTCGCACCGGAACAGGGGATGGGAAACGTTCACGGATGCCGTTATCAAGAAATTAAGCGACGAACGGGAAAATCTAATA
TTCATGTTATGGGGCAGTTACGCTAAAGCCAAGATTTCCCTTATCGATACGAGCCGACATTTGGTCCTAACGACCGTACA
TCCATCTCCCCGCTCCGCCGAATATGGTTTCTTCGGTTGTAAGCATTTCAGTAAGGCTAATGATTTCTTACGGGGTAAAG
GCATCCCGGAAATCGATTGGTAA

Upstream 100 bases:

>100_bases
TGTTTTCTTATTTAAATTCAAATCGGAAGGCAAACTTACACAAAATCCTCGAATTTTAAGCTTTTCTCCGTACCTTTGGT
GGAAGAATAAGAAAAACACC

Downstream 100 bases:

>100_bases
GTATAAATCAACCTAAATCAATCGCATATGGATATTCAAACGTTTATCGACAACTATCAGGAGACATTCTCCGGCAAAGC
GGAATTACCGATCGCTTTCT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG 1 [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQIFHIFNACPFEKVKVVILGQDPYPNPGQYYGVCFSV
PDGVAIPGSLMNIFKEIYDDLGKPIPSSGNLDRWVSQGVFPMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLI
FMLWGSYAKAKISLIDTSRHLVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW

Sequences:

>Translated_220_residues
MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQIFHIFNACPFEKVKVVILGQDPYPNPGQYYGVCFSV
PDGVAIPGSLMNIFKEIYDDLGKPIPSSGNLDRWVSQGVFPMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLI
FMLWGSYAKAKISLIDTSRHLVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW
>Mature_220_residues
MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQIFHIFNACPFEKVKVVILGQDPYPNPGQYYGVCFSV
PDGVAIPGSLMNIFKEIYDDLGKPIPSSGNLDRWVSQGVFPMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLI
FMLWGSYAKAKISLIDTSRHLVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=219, Percent_Identity=52.5114155251142, Blast_Score=225, Evalue=2e-59,
Organism=Homo sapiens, GI6224979, Length=219, Percent_Identity=52.5114155251142, Blast_Score=225, Evalue=3e-59,
Organism=Escherichia coli, GI1788934, Length=215, Percent_Identity=47.4418604651163, Blast_Score=200, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI17556304, Length=217, Percent_Identity=48.3870967741936, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6323620, Length=233, Percent_Identity=43.3476394849785, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25182; Mature: 25182

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQIFHIFNACPFEKVKVV
CCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHCCCCCCCCCEEEE
ILGQDPYPNPGQYYGVCFSVPDGVAIPGSLMNIFKEIYDDLGKPIPSSGNLDRWVSQGVF
EECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
PMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLIFMLWGSYAKAKISLIDTSRH
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCE
LVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNVRIDESWRKRLQEEFDKPYFEQLVTFVKNEYKQAHVLPPGPQIFHIFNACPFEKVKVV
CCCEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCHHHHCCCCCCCCCEEEE
ILGQDPYPNPGQYYGVCFSVPDGVAIPGSLMNIFKEIYDDLGKPIPSSGNLDRWVSQGVF
EECCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
PMNSVLTVRAHQTGSHRNRGWETFTDAVIKKLSDERENLIFMLWGSYAKAKISLIDTSRH
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCE
LVLTTVHPSPRSAEYGFFGCKHFSKANDFLRGKGIPEIDW
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA