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The map label for this gene is lolC [H]

Identifier: 150008637

GI number: 150008637

Start: 2390617

End: 2391861

Strand: Reverse

Name: lolC [H]

Synonym: BDI_2025

Alternate gene names: 150008637

Gene position: 2391861-2390617 (Counterclockwise)

Preceding gene: 150008638

Following gene: 150008636

Centisome position: 49.71

GC content: 43.53

Gene sequence:

>1245_bases
ATGAATTTAGAGCTATTTATCGCCAAAAAGATACATTTCAGCAAGGAGGGGGATCGAGAGGTTACTCCTCCCGCTGTTCG
TATTGCCATGATCGGGATCGCCTTGGGATTGGCGGTGATGATTCTTTCGGTGGCGATCGTGATAGGCTTTAAGAAAGAGG
TCCGGAACAAAGTGATCGGTTTCGGCTCGCATATCCAGATCACGAATTTCGATAGTAATTCTTCCTATGAGTCGCAGCCG
ATAGCGGTTAGCGATACTTTATTGAATGCGCTCGATGCATTCCCCGGTATTCGCCATGTCGAGAAATTTGCGACGAAGCT
AGGCATCTTGAAGACTGACCAAGATTTTCAAGGAATTGTCTTGAAAGGGGTGGACACGGATTATGACTGGACTTTCTTCA
AGGATAATTTAAAAGAAGGCGAGATCTTTACGATCCAACCGGATAAGAACTCTACAGATGTTATTATTTCCAAGTATTTA
TCAGATCTGCTAGGACTAAAGGTAGGGGATTCTTTCCTGACTTATTTTGTGCAAGATGACGTGCGTGCCCGTAAGTTCAC
GATCACGGGGATTTATGAGACGGGTTTCCTTGATTATGACAAGATGTTCGTAATCGCTGATATTAAGCAGATACGCCGCT
TGAACGGTTGGGATAAAGATCAAGTAAGCGGACTGGAGTTGCAAGTGGATGACTATGATCGTTTGGACCAAGTGGCCGAG
GATGTTTATTTCGATCTGACGGAACGGCAAGACCGAAATGGCAATACGTTCTACGCCCGCTCGATCAAGGAGTTGAACCC
GATGATCTTTAATTGGCTGGATGTGCTGGACATCAATGTGGTGGTTATCTTGGCGCTGATGCTTTCCGTCGCAGGGTTTA
CCATGATCTCCGGATTATTGATCATAATCTTAGAGCGTACCAATATGATCGGAATCCTAAAAGCCTTGGGACAAAATAAT
AACAGTATTCGCAAGATCTTCTTGTATGTCTCTTTCTTCTTGATCGGCAAAGGAATGTTGTGGGGGAATATCATCGGTAT
CTCTCTTTGTTTGCTTCAATCTCATTTCCACATTATCCAATTAGATCCTTCTATTTATTATTTGGATGCCGTGCCTATCG
ATCTGAGCCTATTTTCACTGTTCCTTTTGAATATAGGGACATTGGTCGCCTCCATGTTGATGATGTTAGGACCTTCCTAT
TTGATTACGAAGATTGATCCGGCCAAGAGTATCCGTTTTGAATAA

Upstream 100 bases:

>100_bases
TGAGGTTCGTATGGCCTATGTCTTGAAAAAGGAAGATTTGGCGAAAGCTTTGACGGTGTTATCAAAGGCGCTGGAAGCTT
ATCCGGGAAGAATGTTATAA

Downstream 100 bases:

>100_bases
AAGCCGTATCTTTGGCATACGTTCTAGTTTTGCCGGATTGATATGACAGATCTTATCTCTAAAGAAAAGCGTAGCTATAT
CATGTCTATGATTAAGGGCA

Product: putative transmembrane permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSVAIVIGFKKEVRNKVIGFGSHIQITNFDSNSSYESQP
IAVSDTLLNALDAFPGIRHVEKFATKLGILKTDQDFQGIVLKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYL
SDLLGLKVGDSFLTYFVQDDVRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWDKDQVSGLELQVDDYDRLDQVAE
DVYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVLDINVVVILALMLSVAGFTMISGLLIIILERTNMIGILKALGQNN
NSIRKIFLYVSFFLIGKGMLWGNIIGISLCLLQSHFHIIQLDPSIYYLDAVPIDLSLFSLFLLNIGTLVASMLMMLGPSY
LITKIDPAKSIRFE

Sequences:

>Translated_414_residues
MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSVAIVIGFKKEVRNKVIGFGSHIQITNFDSNSSYESQP
IAVSDTLLNALDAFPGIRHVEKFATKLGILKTDQDFQGIVLKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYL
SDLLGLKVGDSFLTYFVQDDVRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWDKDQVSGLELQVDDYDRLDQVAE
DVYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVLDINVVVILALMLSVAGFTMISGLLIIILERTNMIGILKALGQNN
NSIRKIFLYVSFFLIGKGMLWGNIIGISLCLLQSHFHIIQLDPSIYYLDAVPIDLSLFSLFLLNIGTLVASMLMMLGPSY
LITKIDPAKSIRFE
>Mature_414_residues
MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSVAIVIGFKKEVRNKVIGFGSHIQITNFDSNSSYESQP
IAVSDTLLNALDAFPGIRHVEKFATKLGILKTDQDFQGIVLKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYL
SDLLGLKVGDSFLTYFVQDDVRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWDKDQVSGLELQVDDYDRLDQVAE
DVYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVLDINVVVILALMLSVAGFTMISGLLIIILERTNMIGILKALGQNN
NSIRKIFLYVSFFLIGKGMLWGNIIGISLCLLQSHFHIIQLDPSIYYLDAVPIDLSLFSLFLLNIGTLVASMLMMLGPSY
LITKIDPAKSIRFE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=411, Percent_Identity=24.330900243309, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787360, Length=403, Percent_Identity=19.8511166253102, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46734; Mature: 46734

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSVAIVIGFKKEVRNKVIG
CCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FGSHIQITNFDSNSSYESQPIAVSDTLLNALDAFPGIRHVEKFATKLGILKTDQDFQGIV
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCEECCCCCCCEE
LKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYLSDLLGLKVGDSFLTYFVQDD
EECCCCCCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWDKDQVSGLELQVDDYDRLDQVAE
CCEEEEEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHH
DVYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVLDINVVVILALMLSVAGFTMISGLL
HHHEEHHHCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIILERTNMIGILKALGQNNNSIRKIFLYVSFFLIGKGMLWGNIIGISLCLLQSHFHIIQ
EEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
LDPSIYYLDAVPIDLSLFSLFLLNIGTLVASMLMMLGPSYLITKIDPAKSIRFE
ECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MNLELFIAKKIHFSKEGDREVTPPAVRIAMIGIALGLAVMILSVAIVIGFKKEVRNKVIG
CCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FGSHIQITNFDSNSSYESQPIAVSDTLLNALDAFPGIRHVEKFATKLGILKTDQDFQGIV
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHCCEECCCCCCCEE
LKGVDTDYDWTFFKDNLKEGEIFTIQPDKNSTDVIISKYLSDLLGLKVGDSFLTYFVQDD
EECCCCCCCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
VRARKFTITGIYETGFLDYDKMFVIADIKQIRRLNGWDKDQVSGLELQVDDYDRLDQVAE
CCEEEEEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHH
DVYFDLTERQDRNGNTFYARSIKELNPMIFNWLDVLDINVVVILALMLSVAGFTMISGLL
HHHEEHHHCCCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIILERTNMIGILKALGQNNNSIRKIFLYVSFFLIGKGMLWGNIIGISLCLLQSHFHIIQ
EEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
LDPSIYYLDAVPIDLSLFSLFLLNIGTLVASMLMMLGPSYLITKIDPAKSIRFE
ECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]