Click here to switch to the map view.

The map label for this gene is trxA [H]

Identifier: 150008592

GI number: 150008592

Start: 2342946

End: 2343305

Strand: Reverse

Name: trxA [H]

Synonym: BDI_1978

Alternate gene names: 150008592

Gene position: 2343305-2342946 (Counterclockwise)

Preceding gene: 150008594

Following gene: 150008590

Centisome position: 48.7

GC content: 42.5

Gene sequence:

>360_bases
ATGGTAGTGATCGATTTAACGAAAGATGGTTTTATCGCCAATGTCGGTGATTTTGAGGCCAATCCCAAAGATTGGAAATA
TATAGGAAGTCGTCCTTGCCTCATAGATTTTCACGCTCCTTGGTGCGGTTATTGCAAACGCTTAAGCCCGATATTGGATG
AGTTTGCCAAAGAATTTGATGGGAAGATTTATATTTATAAGGTGGATGTAGATCAAGAGGAGGCACTCGAGACAGCCTTT
AATATCCGAACGATTCCCACTTTGATGTTTTGCCCGCTAGACGGCCCCCGTGAGATGATGATCGGCACGATGGGAAAACT
GGAGTTAAAGCAGTTGATTCAGGAAAAATTGTTGAAGTAA

Upstream 100 bases:

>100_bases
ATTCTGTCTGTATGTTAAAACGATGTCGCGAAAGTATAAAAAATACCGCAACCTATTCATACTTATCTTTGTTATATTAT
AAATCAAAATATAGAGAAGT

Downstream 100 bases:

>100_bases
TATAATATGGATATATGGTGTGGGGTGTAGAGACGTAGCGTGTATGCTGCGTCTCTATTTTTTGCTTTCTTATTATATGA
ATTGAATGAATAGTAACCCC

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGYCKRLSPILDEFAKEFDGKIYIYKVDVDQEEALETAF
NIRTIPTLMFCPLDGPREMMIGTMGKLELKQLIQEKLLK

Sequences:

>Translated_119_residues
MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGYCKRLSPILDEFAKEFDGKIYIYKVDVDQEEALETAF
NIRTIPTLMFCPLDGPREMMIGTMGKLELKQLIQEKLLK
>Mature_119_residues
MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGYCKRLSPILDEFAKEFDGKIYIYKVDVDQEEALETAF
NIRTIPTLMFCPLDGPREMMIGTMGKLELKQLIQEKLLK

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=84, Percent_Identity=38.0952380952381, Blast_Score=70, Evalue=3e-14,
Organism=Escherichia coli, GI1788936, Length=86, Percent_Identity=37.2093023255814, Blast_Score=70, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI115532380, Length=95, Percent_Identity=33.6842105263158, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544108, Length=95, Percent_Identity=33.6842105263158, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532378, Length=95, Percent_Identity=33.6842105263158, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639826, Length=69, Percent_Identity=36.231884057971, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 13694; Mature: 13694

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGYCKRLSPILDEFAKEFD
CEEEEECCCCCEEECCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
GKIYIYKVDVDQEEALETAFNIRTIPTLMFCPLDGPREMMIGTMGKLELKQLIQEKLLK
CEEEEEEECCCHHHHHHHHHCCEECCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVIDLTKDGFIANVGDFEANPKDWKYIGSRPCLIDFHAPWCGYCKRLSPILDEFAKEFD
CEEEEECCCCCEEECCCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHC
GKIYIYKVDVDQEEALETAFNIRTIPTLMFCPLDGPREMMIGTMGKLELKQLIQEKLLK
CEEEEEEECCCHHHHHHHHHCCEECCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]