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The map label for this gene is bioC [H]

Identifier: 150008531

GI number: 150008531

Start: 2276597

End: 2277358

Strand: Direct

Name: bioC [H]

Synonym: BDI_1917

Alternate gene names: 150008531

Gene position: 2276597-2277358 (Clockwise)

Preceding gene: 150008530

Following gene: 150008532

Centisome position: 47.32

GC content: 53.28

Gene sequence:

>762_bases
ATGGAAGTAATCGAACAAGAACGGATCCGCCGGCGTTTCAGCCAAGCGGTGAATACATACGACGATCACGCGGATGCCCA
GAAACGGATATGCGCCCATCTGGTACAGCTATTGACCGTATACACCTCCTCTCATTTCCGCAGGGTGCTGGAAATCGGTT
GCGGAAGCGGCGGATTCACCCGTTTATTAAAACAAGAATGCCAAATCGAGGAATGGGTACTCAACGATCTTTGCGAGACT
TGGCAAAGCGCCATCGAGGAGTTGTTTCCTTCCGCCACTCCTCTATTCTTGGCCGGTGATGCCGAGCGACTGGCTTTTCC
CGGCACGTTCGACTTGATTGCCTCGGCCTCCGCCCTGCAATGGATGAAAGACCTTCCACGTTTCCTCCATAAGCTATCGT
CCACCCTATCGCCCGGAGGCATGCTGGCTTTCAACACCTTCACGCCAGACAACCTTCACGAGATCAAGGAACTGACCGGA
GAAGGGCTCACCTATCCTACCGCCGGACAATTAAGGGAGTGGTTATCCACCTACTTCCAGATCGTCCATGAAGAGGAAGG
AAATATCGCCCTGACCTTCCGGCACCCGCTGGAGGTGCTAAGACATCTAAAGTACACGGGGGTCACGGCCAACGCCTCTT
GCGTCTGGACACGGGGAAAACAGGAACGTTTCTGCCGGGATTATCAAGAGAGATTCCCCTCGGCGGATGGTGGGGTCACA
TTAACTTACCGTCCACTCTATATCTTAGTGGTCAAAAGATAA

Upstream 100 bases:

>100_bases
CGGCAACCAACCTCCGGAACTACTGGCAAGGCCGTTGCCCCATCCAAGAGATCAAGGCGCCTCATCTTCCTTTTTACCAC
TATCAATCATGGAACGAATT

Downstream 100 bases:

>100_bases
AGGTGAGGTAGGTCGCCTCTTCCGAGGTATTGATCCTTTCACCTATATGATATGATCGTATCACAAGGGTGAAACGATCT
TTTCACCTAGGTGATACGTT

Product: biotin synthesis protein, BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSSHFRRVLEIGCGSGGFTRLLKQECQIEEWVLNDLCET
WQSAIEELFPSATPLFLAGDAERLAFPGTFDLIASASALQWMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTG
EGLTYPTAGQLREWLSTYFQIVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTRGKQERFCRDYQERFPSADGGVT
LTYRPLYILVVKR

Sequences:

>Translated_253_residues
MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSSHFRRVLEIGCGSGGFTRLLKQECQIEEWVLNDLCET
WQSAIEELFPSATPLFLAGDAERLAFPGTFDLIASASALQWMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTG
EGLTYPTAGQLREWLSTYFQIVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTRGKQERFCRDYQERFPSADGGVT
LTYRPLYILVVKR
>Mature_253_residues
MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSSHFRRVLEIGCGSGGFTRLLKQECQIEEWVLNDLCET
WQSAIEELFPSATPLFLAGDAERLAFPGTFDLIASASALQWMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTG
EGLTYPTAGQLREWLSTYFQIVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTRGKQERFCRDYQERFPSADGGVT
LTYRPLYILVVKR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=244, Percent_Identity=27.4590163934426, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28948; Mature: 28948

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSSHFRRVLEIGCGSGGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RLLKQECQIEEWVLNDLCETWQSAIEELFPSATPLFLAGDAERLAFPGTFDLIASASALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCHHHHHHHHHHHH
WMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTGEGLTYPTAGQLREWLSTYFQ
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTRGKQERFCRDYQERFPSADGGVT
HHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEE
LTYRPLYILVVKR
EEECCEEEEEECC
>Mature Secondary Structure
MEVIEQERIRRRFSQAVNTYDDHADAQKRICAHLVQLLTVYTSSHFRRVLEIGCGSGGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
RLLKQECQIEEWVLNDLCETWQSAIEELFPSATPLFLAGDAERLAFPGTFDLIASASALQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCHHHHHHHHHHHH
WMKDLPRFLHKLSSTLSPGGMLAFNTFTPDNLHEIKELTGEGLTYPTAGQLREWLSTYFQ
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IVHEEEGNIALTFRHPLEVLRHLKYTGVTANASCVWTRGKQERFCRDYQERFPSADGGVT
HHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEE
LTYRPLYILVVKR
EEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]