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The map label for this gene is katA [H]

Identifier: 150008366

GI number: 150008366

Start: 2062783

End: 2064249

Strand: Direct

Name: katA [H]

Synonym: BDI_1740

Alternate gene names: 150008366

Gene position: 2062783-2064249 (Clockwise)

Preceding gene: 150008364

Following gene: 150008372

Centisome position: 42.87

GC content: 50.58

Gene sequence:

>1467_bases
ATGGAAGACAAAAAACTAACTGCCGCCAACGGGCGCCCTGTTGCGGACAATCAGAACGTACAAACAGTGGGGCCACGTGG
CCCGATGGTATTACAAGACCCTTGGTTCATTGAGAAGCTAGCGCACTTCGACCGTGAAGTGATCCCAGAAAGACGCATGC
ACGCCAAAGGTTCCGGCGCATTCGGTACCTTTACCGTTACACATGATATCACAAAGTATACGAAAGCGGCTATTTTCAGC
GAGGTAGGCAAGAAAACTGACTGCTTTGTCCGTTTCTCCACCGTAGCCGGAGAGCGCGGAGCAGCCGACGCAGAGCGTGA
TATCCGTGGATTCGCCATGAAATTCTACACAGAGGAGGGCAACTGGGACTTAGTGGGTAACAACACCCCGGTATTTTTCT
TGCGTGATCCCCTAAAATTCCCTGACTTGAATCATGCGATCAAACGTGACCCGAAAACGAATCTACGAAGCGAGGATAAC
AACTGGGATTTCTGGACTTTGCTTCCCGAGGCCCTGCATCAAGTAACGATTACGATGAGTTCTCGCGGCATTCCTTACTC
TTATCGACATATGCATGGTTTCGGTAGCCATACGTACAGTTTTATCAACGATAAGAACGAACGTATCTGGGTGAAGTTCC
ATCTCAGAACCCTGCAAGGTATCAAGAACTTGAGTGACGAGGAAGCGGCTGCGATCATCGCCAAGGATCGTGAATCCCAT
CAGCGTGATTTGTTCGAGAGTATCGAGCGTGGGGACTTCCCGAAATGGAAATTCCAGATCCAATTGATGACTGAAGAGCA
GGCCGAGACCTATCCGATCAACCCATTCGACCTCACGAAAGTATGGCCGCATAAGGACTTCCCGTTAATGGATGTCGGTA
TCCTCGAGTTGAACCGTAATCCGGAGAATTATTTCCAAGACGTGGAGCAAGCCGCATTCAACCCGATGAATACTGTCGAA
GGCATCGGCTTCTCCCCAGACAAGATGTTACAAGGTCGTCTATTCTCTTATGGCGACGCCCAGCGTTACCGCCTTGGCGT
GAACCTAGAGCAGATCCCGGTGAACAAGCCCCGTTGTCCGTTCCATGCCTATCACCGTGACGGAACGATGCGTGTAGACG
GAAACTATGGAGCCGCAAAGGGTTACGAACCTAACAGCTTCGGCGAATGGAAAGACTCTCCCGAGAAGAAGGAACCGCCT
TTGAAAGTACACGGGGATGTTTATAATTACAACGAGCGTGAGTACGATGATGATTACTACAGCCAACCGGGTGCCTTATT
CCGTTTGATGCCGCCGGAAGAGCAACAGTTGTTATTCGGCAATACCGCCCGTGCGATGGGTAACGCCCAACTGTTCATCA
AGCAACGCCACGTACGCAATTGCTACAAGGCAGACCCTGCTTACGGTAAGGGAGTAGCTGAAGCTCTAGGAATCAGCTTG
GAAGAGGCCTTGAAAGAAGACCGATAA

Upstream 100 bases:

>100_bases
ATTTTTGTCAGGAAGTTAAAAACAATTGTTGTTTCTAAACAGTTTTATTTAAAGATTACTTTATCTAAAATTCTTTATTG
CGACATAAAAAACTAAAGTT

Downstream 100 bases:

>100_bases
AGTAGTAAGGCTACGATAGAAAGCGATAAAAGAGGGATAACCCCAGTAATCCTATGGATGAACGGGTTATCTCATTCTTT
TTTAGTAGGATAAGAGAGGA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITKYTKAAIFS
EVGKKTDCFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAIKRDPKTNLRSEDN
NWDFWTLLPEALHQVTITMSSRGIPYSYRHMHGFGSHTYSFINDKNERIWVKFHLRTLQGIKNLSDEEAAAIIAKDRESH
QRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPFDLTKVWPHKDFPLMDVGILELNRNPENYFQDVEQAAFNPMNTVE
GIGFSPDKMLQGRLFSYGDAQRYRLGVNLEQIPVNKPRCPFHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKDSPEKKEPP
LKVHGDVYNYNEREYDDDYYSQPGALFRLMPPEEQQLLFGNTARAMGNAQLFIKQRHVRNCYKADPAYGKGVAEALGISL
EEALKEDR

Sequences:

>Translated_488_residues
MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITKYTKAAIFS
EVGKKTDCFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAIKRDPKTNLRSEDN
NWDFWTLLPEALHQVTITMSSRGIPYSYRHMHGFGSHTYSFINDKNERIWVKFHLRTLQGIKNLSDEEAAAIIAKDRESH
QRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPFDLTKVWPHKDFPLMDVGILELNRNPENYFQDVEQAAFNPMNTVE
GIGFSPDKMLQGRLFSYGDAQRYRLGVNLEQIPVNKPRCPFHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKDSPEKKEPP
LKVHGDVYNYNEREYDDDYYSQPGALFRLMPPEEQQLLFGNTARAMGNAQLFIKQRHVRNCYKADPAYGKGVAEALGISL
EEALKEDR
>Mature_488_residues
MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFDREVIPERRMHAKGSGAFGTFTVTHDITKYTKAAIFS
EVGKKTDCFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAIKRDPKTNLRSEDN
NWDFWTLLPEALHQVTITMSSRGIPYSYRHMHGFGSHTYSFINDKNERIWVKFHLRTLQGIKNLSDEEAAAIIAKDRESH
QRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPFDLTKVWPHKDFPLMDVGILELNRNPENYFQDVEQAAFNPMNTVE
GIGFSPDKMLQGRLFSYGDAQRYRLGVNLEQIPVNKPRCPFHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKDSPEKKEPP
LKVHGDVYNYNEREYDDDYYSQPGALFRLMPPEEQQLLFGNTARAMGNAQLFIKQRHVRNCYKADPAYGKGVAEALGISL
EEALKEDR

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. May be involved in aerotolerance of B.fragilis [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=476, Percent_Identity=53.781512605042, Blast_Score=512, Evalue=1e-145,
Organism=Escherichia coli, GI48994891, Length=498, Percent_Identity=42.570281124498, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=50.3171247357294, Blast_Score=469, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI25151141, Length=473, Percent_Identity=49.6828752642706, Blast_Score=458, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI25147792, Length=473, Percent_Identity=49.4714587737844, Blast_Score=458, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6320462, Length=488, Percent_Identity=46.5163934426229, Blast_Score=401, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321525, Length=537, Percent_Identity=37.243947858473, Blast_Score=314, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17981717, Length=477, Percent_Identity=48.6373165618449, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI19920968, Length=479, Percent_Identity=45.9290187891441, Blast_Score=440, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 56168; Mature: 56168

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFDREVIPERRMHAKGSGA
CCCCEEECCCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHCCHHHHCCCCCCC
FGTFTVTHDITKYTKAAIFSEVGKKTDCFVRFSTVAGERGAADAERDIRGFAMKFYTEEG
EEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHEEEEEEEEECC
NWDLVGNNTPVFFLRDPLKFPDLNHAIKRDPKTNLRSEDNNWDFWTLLPEALHQVTITMS
CEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEE
SRGIPYSYRHMHGFGSHTYSFINDKNERIWVKFHLRTLQGIKNLSDEEAAAIIAKDRESH
CCCCCCHHHHHCCCCCCEEHEECCCCCEEEEEEEEHHHHHHHCCCCHHHHEEEECCHHHH
QRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPFDLTKVWPHKDFPLMDVGILELNRN
HHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCC
PENYFQDVEQAAFNPMNTVEGIGFSPDKMLQGRLFSYGDAQRYRLGVNLEQIPVNKPRCP
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCHHCCCCCCCCCC
FHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKDSPEKKEPPLKVHGDVYNYNEREYDDDYY
CEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCHHH
SQPGALFRLMPPEEQQLLFGNTARAMGNAQLFIKQRHVRNCYKADPAYGKGVAEALGISL
CCCCCEEEECCCCCCCEEECCHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCH
EEALKEDR
HHHHHCCC
>Mature Secondary Structure
MEDKKLTAANGRPVADNQNVQTVGPRGPMVLQDPWFIEKLAHFDREVIPERRMHAKGSGA
CCCCEEECCCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHCCHHHHCCCCCCC
FGTFTVTHDITKYTKAAIFSEVGKKTDCFVRFSTVAGERGAADAERDIRGFAMKFYTEEG
EEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHEEEEEEEEECC
NWDLVGNNTPVFFLRDPLKFPDLNHAIKRDPKTNLRSEDNNWDFWTLLPEALHQVTITMS
CEEEECCCCCEEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEEEEEEE
SRGIPYSYRHMHGFGSHTYSFINDKNERIWVKFHLRTLQGIKNLSDEEAAAIIAKDRESH
CCCCCCHHHHHCCCCCCEEHEECCCCCEEEEEEEEHHHHHHHCCCCHHHHEEEECCHHHH
QRDLFESIERGDFPKWKFQIQLMTEEQAETYPINPFDLTKVWPHKDFPLMDVGILELNRN
HHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCCCCEECCCCCCCEEEEEEEEECCC
PENYFQDVEQAAFNPMNTVEGIGFSPDKMLQGRLFSYGDAQRYRLGVNLEQIPVNKPRCP
HHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHCCCCCCCCCCEEEECCCHHCCCCCCCCCC
FHAYHRDGTMRVDGNYGAAKGYEPNSFGEWKDSPEKKEPPLKVHGDVYNYNEREYDDDYY
CEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCHHH
SQPGALFRLMPPEEQQLLFGNTARAMGNAQLFIKQRHVRNCYKADPAYGKGVAEALGISL
CCCCCEEEECCCCCCCEEECCHHHHCCCEEEEEEHHHHHHHHHCCCCCCCCHHHHHCCCH
EEALKEDR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7768808 [H]