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The map label for this gene is pdxJ

Identifier: 150008179

GI number: 150008179

Start: 1809871

End: 1810587

Strand: Direct

Name: pdxJ

Synonym: BDI_1545

Alternate gene names: 150008179

Gene position: 1809871-1810587 (Clockwise)

Preceding gene: 150008165

Following gene: 150008180

Centisome position: 37.62

GC content: 44.63

Gene sequence:

>717_bases
ATGACAAATTTAAGTGTAAACATTAACAAGGTTGCTACTATTCGTAATGCGAGAGGTGGCAATATGCCAAACGTGCTGAA
AGTGGCGCAAGACTGTGAATTATTCGGGGCACAAGGAATTACGGTTCATCCCCGTCCGGATGAACGACACATACGCTATA
GCGATGTTTATGGACTAAAACCTCTTATCCGGACAGAATTTAACATAGAAGGCTATCCTTGTGATAAATTCATCGACTTG
GTATTGAAGGTAAAACCGACCCAAGTCACACTGGTTCCGGACGCTCCGGATGCCATCACGTCGAACTCAGGTTGGAACGT
AAAGGACAATTTCGATTACTTAAGCGAATTGGTAGACACCTTTACCTCACAAGGAATCCGTACATCCATCTTCGTCGGAA
CAGACTTGGCGAATATCGAGCTAGCGGCGAAAACAGGTACGGACCGTATTGAATTATATACGGAACCTTATGCGACCTAT
TATCCGGAAGATCGTGACAAAGCGATCGCTCCTTTTGTCGAGGCCGCGCAATTAGCTAAAAACTTAGGATTAGGCGTAAA
TGCCGGACACGATTTGAACTTAGAAAATCTGGCTTTCTTCAACAAGAATATCCCTTGGCTGGAGGAGGTTTCTATCGGCC
ATGCCTTGATTTGTGATGCGCTCTACCATGGTTTGCAAGAGACGATCGCTTTATACAAGGCATGCTTGAATAGTTGA

Upstream 100 bases:

>100_bases
AATCTTTCACCAACATTATTCTGTTAATTCCCTAAATCCTGCTAAATTTGCCGATACTTTTGTGCAAATGTAATGAAAGA
AAAAAGATATACGATATACA

Downstream 100 bases:

>100_bases
CAAGTGACAGTTTATAGTTATAAATCATAAATTATAATTCATAATTCGAAACGATGAGTATTTTACTTTCACTACAGGCC
GTGGGCTCTCAGGCGGCAGA

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHPRPDERHIRYSDVYGLKPLIRTEFNIEGYPCDKFIDL
VLKVKPTQVTLVPDAPDAITSNSGWNVKDNFDYLSELVDTFTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATY
YPEDRDKAIAPFVEAAQLAKNLGLGVNAGHDLNLENLAFFNKNIPWLEEVSIGHALICDALYHGLQETIALYKACLNS

Sequences:

>Translated_238_residues
MTNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHPRPDERHIRYSDVYGLKPLIRTEFNIEGYPCDKFIDL
VLKVKPTQVTLVPDAPDAITSNSGWNVKDNFDYLSELVDTFTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATY
YPEDRDKAIAPFVEAAQLAKNLGLGVNAGHDLNLENLAFFNKNIPWLEEVSIGHALICDALYHGLQETIALYKACLNS
>Mature_237_residues
TNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHPRPDERHIRYSDVYGLKPLIRTEFNIEGYPCDKFIDLV
LKVKPTQVTLVPDAPDAITSNSGWNVKDNFDYLSELVDTFTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATYY
PEDRDKAIAPFVEAAQLAKNLGLGVNAGHDLNLENLAFFNKNIPWLEEVSIGHALICDALYHGLQETIALYKACLNS

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=231, Percent_Identity=35.4978354978355, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_PARD8 (A6LC86)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001302922.1
- ProteinModelPortal:   A6LC86
- SMR:   A6LC86
- STRING:   A6LC86
- GeneID:   5306698
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_1545
- eggNOG:   COG0854
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BioCyc:   PDIS435591:BDI_1545-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26377; Mature: 26246

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: ACT_SITE 43-43 ACT_SITE 70-70 ACT_SITE 190-190 BINDING 7-7 BINDING 18-18 BINDING 45-45 BINDING 50-50 BINDING 100-100 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHPRPDERHIRYSDVYGLK
CCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEHHCCCCC
PLIRTEFNIEGYPCDKFIDLVLKVKPTQVTLVPDAPDAITSNSGWNVKDNFDYLSELVDT
HHHHEECCCCCCCHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
FTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATYYPEDRDKAIAPFVEAAQLAK
HHCCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
NLGLGVNAGHDLNLENLAFFNKNIPWLEEVSIGHALICDALYHGLQETIALYKACLNS
HCCCCCCCCCCCCHHHHEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNLSVNINKVATIRNARGGNMPNVLKVAQDCELFGAQGITVHPRPDERHIRYSDVYGLK
CCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCEEEHHCCCCC
PLIRTEFNIEGYPCDKFIDLVLKVKPTQVTLVPDAPDAITSNSGWNVKDNFDYLSELVDT
HHHHEECCCCCCCHHHHHHHHEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
FTSQGIRTSIFVGTDLANIELAAKTGTDRIELYTEPYATYYPEDRDKAIAPFVEAAQLAK
HHCCCCEEEEEEECCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
NLGLGVNAGHDLNLENLAFFNKNIPWLEEVSIGHALICDALYHGLQETIALYKACLNS
HCCCCCCCCCCCCHHHHEEECCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA