| Definition | Parabacteroides distasonis ATCC 8503 chromosome, complete genome. |
|---|---|
| Accession | NC_009615 |
| Length | 4,811,379 |
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The map label for this gene is lacZ [H]
Identifier: 150008059
GI number: 150008059
Start: 1650534
End: 1653356
Strand: Direct
Name: lacZ [H]
Synonym: BDI_1422
Alternate gene names: 150008059
Gene position: 1650534-1653356 (Clockwise)
Preceding gene: 150008042
Following gene: 150008063
Centisome position: 34.3
GC content: 46.16
Gene sequence:
>2823_bases ATGAAGAGATTTTGGAGTATTCCACTTATGCTCATGCTATTCGCATGCCAAACTCCCAAAGAGAGTAGAGAGGAATTATC GCTTGCCGGTTGCTGGGAATTACGATTGGATTCAACAGATGTCACCGAGCAAGTTCAATTACCGGGTACCACGGACACCA ACCAAAAAGGATACCCTAACAATGATAAGGAGGAGACAACTCATTTGTCTAGGCCCTTCCGCTATCAAGGTAAGGCTTGG TATCAGAAAGAGATCACGATTCCGGAGAACTGGGAAGGCAAGAGCATTTGGTTAATCTTGGAGCGAACAAAACCGACCCA AATATGGGTAGATAGCATATATGTCGGTTCATCCGACCATATTTCCACCCCTCAAGAATACGATCTGTCCACATATCTCC GGGCTGGGAAGCATCACTTGACTATTCTAGTCGATAACGGTTTGAGCGTTCCGCCCCAATTATTGGACAATTCACACGCT TATACGGAATCCACGCAGACAAACTGGAACGGTATTATCGGAGACCTGAAATTGGAAGCCCGTCCACAATTCCATATCCG CCGGATACAAGTATATCCACATGCGGATCAAAAAACGGTGGACGTAAAAATAAAGCTTTCAAATCCATTCGAGCAAATGA TCGTAGCCGCCGTTCAAATAGAGATGGAGGCTTTCAACACAGGCTTAGAGCACCATATCAAATTCAATAAGAATATCGTA GTTCAACAAGACGAGATCATATTCCAAATACCGATGGGTGATGACGCCTTGGAATGGAGCGAGTTCTCCCCTACCCTGTA TCGCTTGACCGCGAACATCCAAGGAGAGAATATCCAAGATAGCCAAAGTACTACTTTCGGATTAAGAGATTTCAAAGCAG AAGGAACACAATTCAACATCAACGGATTGACCACCTTCCTTCGTGGAAAACACGATGCTTGCGTATTTCCGCTTACAGGC CATGTACCGATGGATACCGCAGCATGGAGACGCTATTTCCGCATCGCCAAGGAATACGGTATCAATCATTGCCGTTTCCA TTCATGGTGTCCTCCTAAAGCTTGTTTCGAGGCGGCCGATATCGAAGGTTTTTACCTCCAACCGGAACTACCTTTCTGGG GAAAGATGGAAAAGGGCGATACCACTTTGATCCATTTCCTCACCAAAGAAGGATTACAAATACAGGAGGCTTACGGGAAT CACGCCTCTTTCGTCATGATGGCGATCGGCAACGAGCTTTCCGGGGATCAAGAAGCGATGGTAGACATGATCGCCCGTTT CCGTAGTGAGGACGGACGGCATTTATACGCATCTGGATCGAATGACTATCTAGGCTTCAACGGCCCTGCGGCGGGTGACG ATTACTTCACGACCTGTCGAGTCCCCGGCGCTAACGTATTCAGCAACCATACCCGGGGTTCCTTCTCTTTCGCAGATGCG GAGGATGGCGGTTATATCAACCATACCTATCCAAACTCGGTCATGAATTTCGAATCCGCTATCGAACAATGTTCATTGCC TATCATCGGACATGAGACCGGGCAATTCCAATGTTATCCGAATTATGAGGAAATCAAGAAATATACCGGGGCACTAAAAC CTTGGAATCTGGAGATATTCCGCAAACGACTGGGCGAGTCCGGTATGGCCGGACAAGCGGATGATTTCTTCAAGGCTTCC GGTAAATGGATGGCGCAACTTTACCGGGCCGAGATGGAAATGGCGTTCCGTACTCCGGGAATGGCCGGCTTCCAATTATT GGATTTACAGGATTATCCGGGACAGGGCACGGCGTTAGTCGGTATCTTGGACGCTTTTATGGATAATAAGGGCTTGATAA CCGCCAAGGAATGGAAAGAGTCTTGCGATGATGTCGTATTACTGGCTCTCCTACCTAAATTCTGTTACTCTGGGAATGAG GCGCTCAAAGGCTCCATCAAGGTAGCGAACTATACACCTACCACTTTAAAAGGGAAACATCTAACTTGGACCTTGACGAA TAGTCAAGATCAAGTAATCGCCCAAAACAACATACCGCTGCAAATCAATCAAGGTACGTTGGCCGAGGTAGGCCCATTAA ATATCGCTTTACCTGCCATTCAAGAGGCTGAGACCTATACTTTACGGCTGGCGATCGAGGGCACGGATTATCACAATCAT TATCCGTTATGGATTTATCCGGAACATAATAACGTGCAAATCCCTACGGATATCAATGTTATTAAGAAATGGGATAAACA GGCCGAGAACTTATTGGCGAACGGGGCGAAAGTATTGTGGTTCCCGGATGCCAAGACTTACAAGAACGTGACGGTAGAAG GATTATTCCAGACAGATTACTGGAATTACCGGATGTTTAAGTCCATCTGCGAATGGGTAAAGAAACCGGTCTCTCCGGGT ACCCTCGGATTATTAATGAATCCCTCTCATCCGGTTTTCGCTCATTTCCCGACGGATTTCCATACAAACTGGCAATGGTT CACGATGATAAAGAATAGCCATCCGTTGATACTGGACCAGCTTCCGGATAATTACAGGCCAATCGTACAGGTGATCGATA ACGTGGAGCGTAATCATAAATTAGGGATGATCCAAGAATTCAATGTCGGCCCGGGCAAGTTATTAATCTGTATGACAGAC TTGGAAACCCAACAAGAATACCCGGAAGTCCGCCAATTATACCATAGCTTATTAAGTTATATGGATTCCTCCGAGTTCTC GCCTCAGATGACATTAACGCCCGCTCAATTGATTGAGTTATTCACGCATCAAGTCGGAGATTCGAAGATTAAGGAATTAG GGAATATCTCGTATGATGAGTAA
Upstream 100 bases:
>100_bases CTTCTTCTTTTTTCATATCTTCTCCTTAATAAAAAAGCCAAAAATACTACCTTTGTACACTATTAATTAAGTAAACCATA TTTAGAGTAAAAACATTACC
Downstream 100 bases:
>100_bases GCGACCTCACTTTTGACGTATATTCACATAGAGACGCAGCACGCTGCGTCTCTTTCCCTATAATATTCATAATCATCAAA CAAGATAGTCTTTCGTAACG
Product: beta-glycosidase
Products: NA
Alternate protein names: Beta-gal; Lactase [H]
Number of amino acids: Translated: 940; Mature: 940
Protein sequence:
>940_residues MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQVQLPGTTDTNQKGYPNNDKEETTHLSRPFRYQGKAW YQKEITIPENWEGKSIWLILERTKPTQIWVDSIYVGSSDHISTPQEYDLSTYLRAGKHHLTILVDNGLSVPPQLLDNSHA YTESTQTNWNGIIGDLKLEARPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAVQIEMEAFNTGLEHHIKFNKNIV VQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGENIQDSQSTTFGLRDFKAEGTQFNINGLTTFLRGKHDACVFPLTG HVPMDTAAWRRYFRIAKEYGINHCRFHSWCPPKACFEAADIEGFYLQPELPFWGKMEKGDTTLIHFLTKEGLQIQEAYGN HASFVMMAIGNELSGDQEAMVDMIARFRSEDGRHLYASGSNDYLGFNGPAAGDDYFTTCRVPGANVFSNHTRGSFSFADA EDGGYINHTYPNSVMNFESAIEQCSLPIIGHETGQFQCYPNYEEIKKYTGALKPWNLEIFRKRLGESGMAGQADDFFKAS GKWMAQLYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALVGILDAFMDNKGLITAKEWKESCDDVVLLALLPKFCYSGNE ALKGSIKVANYTPTTLKGKHLTWTLTNSQDQVIAQNNIPLQINQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNH YPLWIYPEHNNVQIPTDINVIKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDYWNYRMFKSICEWVKKPVSPG TLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQLPDNYRPIVQVIDNVERNHKLGMIQEFNVGPGKLLICMTD LETQQEYPEVRQLYHSLLSYMDSSEFSPQMTLTPAQLIELFTHQVGDSKIKELGNISYDE
Sequences:
>Translated_940_residues MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQVQLPGTTDTNQKGYPNNDKEETTHLSRPFRYQGKAW YQKEITIPENWEGKSIWLILERTKPTQIWVDSIYVGSSDHISTPQEYDLSTYLRAGKHHLTILVDNGLSVPPQLLDNSHA YTESTQTNWNGIIGDLKLEARPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAVQIEMEAFNTGLEHHIKFNKNIV VQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGENIQDSQSTTFGLRDFKAEGTQFNINGLTTFLRGKHDACVFPLTG HVPMDTAAWRRYFRIAKEYGINHCRFHSWCPPKACFEAADIEGFYLQPELPFWGKMEKGDTTLIHFLTKEGLQIQEAYGN HASFVMMAIGNELSGDQEAMVDMIARFRSEDGRHLYASGSNDYLGFNGPAAGDDYFTTCRVPGANVFSNHTRGSFSFADA EDGGYINHTYPNSVMNFESAIEQCSLPIIGHETGQFQCYPNYEEIKKYTGALKPWNLEIFRKRLGESGMAGQADDFFKAS GKWMAQLYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALVGILDAFMDNKGLITAKEWKESCDDVVLLALLPKFCYSGNE ALKGSIKVANYTPTTLKGKHLTWTLTNSQDQVIAQNNIPLQINQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNH YPLWIYPEHNNVQIPTDINVIKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDYWNYRMFKSICEWVKKPVSPG TLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQLPDNYRPIVQVIDNVERNHKLGMIQEFNVGPGKLLICMTD LETQQEYPEVRQLYHSLLSYMDSSEFSPQMTLTPAQLIELFTHQVGDSKIKELGNISYDE >Mature_940_residues MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQVQLPGTTDTNQKGYPNNDKEETTHLSRPFRYQGKAW YQKEITIPENWEGKSIWLILERTKPTQIWVDSIYVGSSDHISTPQEYDLSTYLRAGKHHLTILVDNGLSVPPQLLDNSHA YTESTQTNWNGIIGDLKLEARPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAVQIEMEAFNTGLEHHIKFNKNIV VQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGENIQDSQSTTFGLRDFKAEGTQFNINGLTTFLRGKHDACVFPLTG HVPMDTAAWRRYFRIAKEYGINHCRFHSWCPPKACFEAADIEGFYLQPELPFWGKMEKGDTTLIHFLTKEGLQIQEAYGN HASFVMMAIGNELSGDQEAMVDMIARFRSEDGRHLYASGSNDYLGFNGPAAGDDYFTTCRVPGANVFSNHTRGSFSFADA EDGGYINHTYPNSVMNFESAIEQCSLPIIGHETGQFQCYPNYEEIKKYTGALKPWNLEIFRKRLGESGMAGQADDFFKAS GKWMAQLYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALVGILDAFMDNKGLITAKEWKESCDDVVLLALLPKFCYSGNE ALKGSIKVANYTPTTLKGKHLTWTLTNSQDQVIAQNNIPLQINQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNH YPLWIYPEHNNVQIPTDINVIKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDYWNYRMFKSICEWVKKPVSPG TLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQLPDNYRPIVQVIDNVERNHKLGMIQEFNVGPGKLLICMTD LETQQEYPEVRQLYHSLLSYMDSSEFSPQMTLTPAQLIELFTHQVGDSKIKELGNISYDE
Specific function: The Wild-Type Enzyme Is An Ineffective Lactase. Two Classes Of Point Mutations Dramatically Improve Activity Of The Enzyme. [C]
COG id: COG3250
COG function: function code G; Beta-galactosidase/beta-glucuronidase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glycosyl hydrolase 2 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008979 - InterPro: IPR011013 - InterPro: IPR014718 - InterPro: IPR006101 - InterPro: IPR013812 - InterPro: IPR006104 - InterPro: IPR004199 - InterPro: IPR006102 - InterPro: IPR006103 - InterPro: IPR017853 - InterPro: IPR013781 [H]
Pfam domain/function: PF02929 Bgal_small_N; PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]
EC number: =3.2.1.23 [H]
Molecular weight: Translated: 107150; Mature: 107150
Theoretical pI: Translated: 5.36; Mature: 5.36
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQVQLPGTTDTNQKGYPN CCCCCCCHHHHHHHHCCCCHHHHHHCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCC NDKEETTHLSRPFRYQGKAWYQKEITIPENWEGKSIWLILERTKPTQIWVDSIYVGSSDH CCHHHHHHCCCCCEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCC ISTPQEYDLSTYLRAGKHHLTILVDNGLSVPPQLLDNSHAYTESTQTNWNGIIGDLKLEA CCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECC RPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAVQIEMEAFNTGLEHHIKFNKNIV CCCEEEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHEEHHHHHCCCCEEEEECCCEE VQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGENIQDSQSTTFGLRDFKAEGTQFNI EEECCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCEEEECCCCEEEE NGLTTFLRGKHDACVFPLTGHVPMDTAAWRRYFRIAKEYGINHCRFHSWCPPKACFEAAD CHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCC IEGFYLQPELPFWGKMEKGDTTLIHFLTKEGLQIQEAYGNHASFVMMAIGNELSGDQEAM CCCEEECCCCCCCCCCCCCCCEEEEEEHHCCCEEEHHCCCCCEEEEEEECCCCCCCHHHH VDMIARFRSEDGRHLYASGSNDYLGFNGPAAGDDYFTTCRVPGANVFSNHTRGSFSFADA HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCCCCEEECCC EDGGYINHTYPNSVMNFESAIEQCSLPIIGHETGQFQCYPNYEEIKKYTGALKPWNLEIF CCCCEEECCCCCHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHHHHCCCCCCCHHHH RKRLGESGMAGQADDFFKASGKWMAQLYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALV HHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH GILDAFMDNKGLITAKEWKESCDDVVLLALLPKFCYSGNEALKGSIKVANYTPTTLKGKH HHHHHHHCCCCCEEHHHHHHCHHHEEHHHHHHHHHCCCCCCEECEEEEEECCCCCCCCCE LTWTLTNSQDQVIAQNNIPLQINQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNH EEEEEECCCCCEEEECCCCEEECCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCC YPLWIYPEHNNVQIPTDINVIKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDY CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEECCC WNYRMFKSICEWVKKPVSPGTLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQ CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCEEEEEEEECCCCEEEEC LPDNYRPIVQVIDNVERNHKLGMIQEFNVGPGKLLICMTDLETQQEYPEVRQLYHSLLSY CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCHHCCHHHHHHHHHHHHH MDSSEFSPQMTLTPAQLIELFTHQVGDSKIKELGNISYDE HCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHCCCCCCC >Mature Secondary Structure MKRFWSIPLMLMLFACQTPKESREELSLAGCWELRLDSTDVTEQVQLPGTTDTNQKGYPN CCCCCCCHHHHHHHHCCCCHHHHHHCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCC NDKEETTHLSRPFRYQGKAWYQKEITIPENWEGKSIWLILERTKPTQIWVDSIYVGSSDH CCHHHHHHCCCCCEECCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCC ISTPQEYDLSTYLRAGKHHLTILVDNGLSVPPQLLDNSHAYTESTQTNWNGIIGDLKLEA CCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECC RPQFHIRRIQVYPHADQKTVDVKIKLSNPFEQMIVAAVQIEMEAFNTGLEHHIKFNKNIV CCCEEEEEEEEEECCCCEEEEEEEEECCCHHHHHHHHHHEEHHHHHCCCCEEEEECCCEE VQQDEIIFQIPMGDDALEWSEFSPTLYRLTANIQGENIQDSQSTTFGLRDFKAEGTQFNI EEECCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEECCEEEECCCCEEEE NGLTTFLRGKHDACVFPLTGHVPMDTAAWRRYFRIAKEYGINHCRFHSWCPPKACFEAAD CHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHCC IEGFYLQPELPFWGKMEKGDTTLIHFLTKEGLQIQEAYGNHASFVMMAIGNELSGDQEAM CCCEEECCCCCCCCCCCCCCCEEEEEEHHCCCEEEHHCCCCCEEEEEEECCCCCCCHHHH VDMIARFRSEDGRHLYASGSNDYLGFNGPAAGDDYFTTCRVPGANVFSNHTRGSFSFADA HHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCCCCCCCEEECCC EDGGYINHTYPNSVMNFESAIEQCSLPIIGHETGQFQCYPNYEEIKKYTGALKPWNLEIF CCCCEEECCCCCHHHHHHHHHHHCCCCEEECCCCCEEECCCHHHHHHHHCCCCCCCHHHH RKRLGESGMAGQADDFFKASGKWMAQLYRAEMEMAFRTPGMAGFQLLDLQDYPGQGTALV HHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH GILDAFMDNKGLITAKEWKESCDDVVLLALLPKFCYSGNEALKGSIKVANYTPTTLKGKH HHHHHHHCCCCCEEHHHHHHCHHHEEHHHHHHHHHCCCCCCEECEEEEEECCCCCCCCCE LTWTLTNSQDQVIAQNNIPLQINQGTLAEVGPLNIALPAIQEAETYTLRLAIEGTDYHNH EEEEEECCCCCEEEECCCCEEECCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCC YPLWIYPEHNNVQIPTDINVIKKWDKQAENLLANGAKVLWFPDAKTYKNVTVEGLFQTDY CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEEECCC WNYRMFKSICEWVKKPVSPGTLGLLMNPSHPVFAHFPTDFHTNWQWFTMIKNSHPLILDQ CCHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCEEEEEEEECCCCEEEEC LPDNYRPIVQVIDNVERNHKLGMIQEFNVGPGKLLICMTDLETQQEYPEVRQLYHSLLSY CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCHHCCHHHHHHHHHHHHH MDSSEFSPQMTLTPAQLIELFTHQVGDSKIKELGNISYDE HCCCCCCCEEEECHHHHHHHHHHHCCCHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA