Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 150008003

GI number: 150008003

Start: 1584597

End: 1585898

Strand: Direct

Name: paaK [H]

Synonym: BDI_1366

Alternate gene names: 150008003

Gene position: 1584597-1585898 (Clockwise)

Preceding gene: 150008000

Following gene: 150008004

Centisome position: 32.93

GC content: 47.62

Gene sequence:

>1302_bases
ATGATGTATTGGCAGAAAGAAATAGAAACCATGGATCGTAAAGATCTGGTAAAATTCCAACTGGAACGACTGAAACAAAC
CATAGAACTAGCGGGCAACTCCCCTTTTTACCATAAGATATTCAAAGAGAAAGGAATTACCCCGGACAGTTTTCAGTCCT
TGGAGGATTTACAAAAACTTCCGTTTACAACGAAAGATGATCTTAGAAATAACTATCCGTTCGGATTGGCTGCCATCCCA
TTACAGAAATGCGTACGTATCCACTCTTCCAGTGGAACGACAGGTAATCCTACCGTTGTCTTACATTCCGCCAAGGACTT
GGACCAATGGGCTAACCAAGTAGCTCGTTGCATGTATATGGTAGGGCTAAGGGATACGGACGTATTCCAGAATACATCCG
GCTACGGCATGTTTACCGGTGGCCTCGGTTTCCAGTATGGAGCAGAAAAATTAGGTGCGTTGACAGTGCCTGCGGCGGCC
GGTAATACCAAACGACAGATTAAGTTCATCACCGATTTCGGCACCACCTGTTTACATATCATACCGAGCTATGCCACTCG
TTTGGCCGAGGTTATGTATGAGGAGGGAATAGACCCCAGAAAGGATACCAAACTACACACCGTATGTATCGGTGCCGAGC
CTCACTCGGAAGAACAACGTAAACGCATCGAGCAGCTTCTGGGTGTCAAGGCTTACAACTGTTTCGGTATGTCGGAGATG
AACGGGCCGGGTGTAGCGTTCGAATGTACGGAGCAGAACGGCTTGCATATCTGGGAAGACAACGTGATCGTAGAGATCGT
AGACCCGGTTACCTTGCAACCGGTGCCCGAGGGAGAGGTCGGAGAATTGGTATTAACCACCATCAACCGGGAGGCGATGC
CTTTACTCCGTTATCGTACCCGTGACCTTACTTGTATCTTACCGGGCGATTGCCCTTGCGGACGTACCCATAAACGCCTA
GCCCGTTTCAAAGGACGTAGCGACGATATGATAATTTTGAAGGGTGTGAACCTGTTCCCCATCCAAATCGAAAAGATATT
GATGCAATTCAAGGAATTGGGCAGCAATTACTTGATCACCCTCGAAACGATCGGCAACAGCGACGAGATGTTGATCGAGG
TAGAGTTGAGCGACCTATTCACCGATGATTATTCAGCCTTACAGCGTTTGACGAAAGGTATCACCCGTCAGTTGAAGGAC
GAATTATTACTTACACCACGTATCAAGCTGGTAGCCAAGGGATCTTTGCCAACCACAGATGGCAAGGCGGTACGAGTGAA
AGATCATCGCAAGCTTTGTTAA

Upstream 100 bases:

>100_bases
CATTACTAATATTTTGACACAAAAGCATGGCGTTATCCAAAATAAAAGATACATTTGCAATCTAATTTCATGAATTAAAC
ACACTCTAATTGAAAAAACG

Downstream 100 bases:

>100_bases
ATAAACAATTAAAATAACACCTTATGACAGTCAATCAAATTTCTATTTTCCTAGAAAACAAGTACGGGAAATTAAGCGAG
ATATTAGCGTTATTGGCGGA

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEKGITPDSFQSLEDLQKLPFTTKDDLRNNYPFGLAAIP
LQKCVRIHSSSGTTGNPTVVLHSAKDLDQWANQVARCMYMVGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAA
GNTKRQIKFITDFGTTCLHIIPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEEQRKRIEQLLGVKAYNCFGMSEM
NGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVPEGEVGELVLTTINREAMPLLRYRTRDLTCILPGDCPCGRTHKRL
ARFKGRSDDMIILKGVNLFPIQIEKILMQFKELGSNYLITLETIGNSDEMLIEVELSDLFTDDYSALQRLTKGITRQLKD
ELLLTPRIKLVAKGSLPTTDGKAVRVKDHRKLC

Sequences:

>Translated_433_residues
MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEKGITPDSFQSLEDLQKLPFTTKDDLRNNYPFGLAAIP
LQKCVRIHSSSGTTGNPTVVLHSAKDLDQWANQVARCMYMVGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAA
GNTKRQIKFITDFGTTCLHIIPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEEQRKRIEQLLGVKAYNCFGMSEM
NGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVPEGEVGELVLTTINREAMPLLRYRTRDLTCILPGDCPCGRTHKRL
ARFKGRSDDMIILKGVNLFPIQIEKILMQFKELGSNYLITLETIGNSDEMLIEVELSDLFTDDYSALQRLTKGITRQLKD
ELLLTPRIKLVAKGSLPTTDGKAVRVKDHRKLC
>Mature_433_residues
MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEKGITPDSFQSLEDLQKLPFTTKDDLRNNYPFGLAAIP
LQKCVRIHSSSGTTGNPTVVLHSAKDLDQWANQVARCMYMVGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAA
GNTKRQIKFITDFGTTCLHIIPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEEQRKRIEQLLGVKAYNCFGMSEM
NGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVPEGEVGELVLTTINREAMPLLRYRTRDLTCILPGDCPCGRTHKRL
ARFKGRSDDMIILKGVNLFPIQIEKILMQFKELGSNYLITLETIGNSDEMLIEVELSDLFTDDYSALQRLTKGITRQLKD
ELLLTPRIKLVAKGSLPTTDGKAVRVKDHRKLC

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=428, Percent_Identity=42.0560747663551, Blast_Score=343, Evalue=1e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48829; Mature: 48829

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEKGITPDSFQSLEDLQKL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHC
PFTTKDDLRNNYPFGLAAIPLQKCVRIHSSSGTTGNPTVVLHSAKDLDQWANQVARCMYM
CCCCHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
VGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAAGNTKRQIKFITDFGTTCLHI
HCCCCCHHHCCCCCCEEEECCCCCHHCHHHHCCEEECCCCCCCCCEEEEEEHHCHHHHHH
IPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEEQRKRIEQLLGVKAYNCFGMSEM
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHCCEECCCCC
NGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVPEGEVGELVLTTINREAMPLLRYRT
CCCCEEEEECCCCCCEEECCCEEEEEECCEEECCCCCCCCCCEEEEECCCHHHHHHHHCC
RDLTCILPGDCPCGRTHKRLARFKGRSDDMIILKGVNLFPIQIEKILMQFKELGSNYLIT
CCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
LETIGNSDEMLIEVELSDLFTDDYSALQRLTKGITRQLKDELLLTPRIKLVAKGSLPTTD
EEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GKAVRVKDHRKLC
CCEEEECCCCCCC
>Mature Secondary Structure
MMYWQKEIETMDRKDLVKFQLERLKQTIELAGNSPFYHKIFKEKGITPDSFQSLEDLQKL
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHC
PFTTKDDLRNNYPFGLAAIPLQKCVRIHSSSGTTGNPTVVLHSAKDLDQWANQVARCMYM
CCCCHHHHCCCCCCCEEHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
VGLRDTDVFQNTSGYGMFTGGLGFQYGAEKLGALTVPAAAGNTKRQIKFITDFGTTCLHI
HCCCCCHHHCCCCCCEEEECCCCCHHCHHHHCCEEECCCCCCCCCEEEEEEHHCHHHHHH
IPSYATRLAEVMYEEGIDPRKDTKLHTVCIGAEPHSEEQRKRIEQLLGVKAYNCFGMSEM
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCHHCCEECCCCC
NGPGVAFECTEQNGLHIWEDNVIVEIVDPVTLQPVPEGEVGELVLTTINREAMPLLRYRT
CCCCEEEEECCCCCCEEECCCEEEEEECCEEECCCCCCCCCCEEEEECCCHHHHHHHHCC
RDLTCILPGDCPCGRTHKRLARFKGRSDDMIILKGVNLFPIQIEKILMQFKELGSNYLIT
CCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
LETIGNSDEMLIEVELSDLFTDDYSALQRLTKGITRQLKDELLLTPRIKLVAKGSLPTTD
EEECCCCCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
GKAVRVKDHRKLC
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]