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The map label for this gene is corA [H]

Identifier: 150007884

GI number: 150007884

Start: 1444335

End: 1445411

Strand: Direct

Name: corA [H]

Synonym: BDI_1244

Alternate gene names: 150007884

Gene position: 1444335-1445411 (Clockwise)

Preceding gene: 150007883

Following gene: 150007886

Centisome position: 30.02

GC content: 44.2

Gene sequence:

>1077_bases
ATGAGACGGAATGAATATACACACAGGAGAAGACATATATCCAACCGGCATTTATCGGACAAGTATTATTACGCCGGCGA
ACATGAGACAGCAACCGGCATCCGTCTCACTCAATACAACGAACAATCTTTGCATACGAAAGAGGTGCGGATAACCGACA
CCTCTTTCAGCAAACTAACCGACTCGAATCAGATCAATTGGTTCGAGGTTAGCGGATTGACCAATGCGGATGCCATTACC
CGTATCGTAAAAGATTTCGGACTGCATAATCTGGACGCTAAGGATATCTTGACTCCCCAACACGTGGTCAAGGTAGAGGA
ATACAAAGGACGAATGCTTATCGTATTAAACTCCTGCTATTACGATGTCAATAACGAGATGCGGTCTGAGCACATCAGCA
TACTGGTAGCTAACAATACGGTTATCACTTTTACGGAAAGCAACAACCCCGTATTCGAGGCCGCTCATAAAGCGCTACTA
TCCAACATGCTGAACATCCGGAAAAAAGGCAGTGGATTGCTGCTCGCTTTCCTTCTAAACACCATCATAGCGAATCTAGT
AGAATCCGCCTCAAAGGTAGAAGAGATACTAGAGGATATAGAAGAGACTTTGCTCGATCCTAAGAACGATCAGGGTAATA
TGGGTTCCCTAATCCAACAACACCGCCATGAGTACATGATTATCCGTAAGAATAGCCTACCGCTGAAAGATCAATTCTCA
AAACTATTACGAACAGAGAACGGGATTATCACCCCGGATATCCTACCGATCTATAATGACCTGCAAGACCAACTCCAATT
CGTTATCCAAACAACGGAAAGCTGCCGGGAAATCACCTCTTCCCTTGTCGATCTTTATATATCCAATAACGATCTTAGGA
TGAACGCCATCATGAAACGGCTGACGATTGTCTCCACCCTTTTCATCCCTTTGACATTCTTGGTGGGCGTATGGGGTATG
AACTTCAAGATAATGCCGGAATTGGATTGGCGTTACGGTTATTTCATCGCTTGGGCCGTCATGATAGCTACCGGAGTATT
GACTTGGCTATATATGAAACGAAAGGATTGGTATTAA

Upstream 100 bases:

>100_bases
GCGCACGGTTCCCGGTGTCCGTCGCTTTCAAGACGAGCATGTGCAGTTCGGAGGCGCCGGTATCACCGTTGTTGAGTTTG
ATTAAAAAGAGATCCTTATT

Downstream 100 bases:

>100_bases
AACCAATCCTTACGATCTGAAGAATTTCTTCCTATACTTATAAAAAGTATTCTTAGAGACGTTGAAATGCTCGCAAATCG
ATCCTACCGATTCTCCCCGC

Product: Mg2+/Co2+ transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSLHTKEVRITDTSFSKLTDSNQINWFEVSGLTNADAIT
RIVKDFGLHNLDAKDILTPQHVVKVEEYKGRMLIVLNSCYYDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALL
SNMLNIRKKGSGLLLAFLLNTIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLIQQHRHEYMIIRKNSLPLKDQFS
KLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCREITSSLVDLYISNNDLRMNAIMKRLTIVSTLFIPLTFLVGVWGM
NFKIMPELDWRYGYFIAWAVMIATGVLTWLYMKRKDWY

Sequences:

>Translated_358_residues
MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSLHTKEVRITDTSFSKLTDSNQINWFEVSGLTNADAIT
RIVKDFGLHNLDAKDILTPQHVVKVEEYKGRMLIVLNSCYYDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALL
SNMLNIRKKGSGLLLAFLLNTIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLIQQHRHEYMIIRKNSLPLKDQFS
KLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCREITSSLVDLYISNNDLRMNAIMKRLTIVSTLFIPLTFLVGVWGM
NFKIMPELDWRYGYFIAWAVMIATGVLTWLYMKRKDWY
>Mature_358_residues
MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSLHTKEVRITDTSFSKLTDSNQINWFEVSGLTNADAIT
RIVKDFGLHNLDAKDILTPQHVVKVEEYKGRMLIVLNSCYYDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALL
SNMLNIRKKGSGLLLAFLLNTIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLIQQHRHEYMIIRKNSLPLKDQFS
KLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCREITSSLVDLYISNNDLRMNAIMKRLTIVSTLFIPLTFLVGVWGM
NFKIMPELDWRYGYFIAWAVMIATGVLTWLYMKRKDWY

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=67, Percent_Identity=43.2835820895522, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 41560; Mature: 41560

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSLHTKEVRITDTSFSKLT
CCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHCC
DSNQINWFEVSGLTNADAITRIVKDFGLHNLDAKDILTPQHVVKVEEYKGRMLIVLNSCY
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHCCCCEEEEEECEE
YDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALLSNMLNIRKKGSGLLLAFLLN
ECCCHHHCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLIQQHRHEYMIIRKNSLPLKDQFS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHH
KLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCREITSSLVDLYISNNDLRMNAIMKR
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
LTIVSTLFIPLTFLVGVWGMNFKIMPELDWRYGYFIAWAVMIATGVLTWLYMKRKDWY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRNEYTHRRRHISNRHLSDKYYYAGEHETATGIRLTQYNEQSLHTKEVRITDTSFSKLT
CCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCEEEEEEECCHHHHCC
DSNQINWFEVSGLTNADAITRIVKDFGLHNLDAKDILTPQHVVKVEEYKGRMLIVLNSCY
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHCCCCEEEEEECEE
YDVNNEMRSEHISILVANNTVITFTESNNPVFEAAHKALLSNMLNIRKKGSGLLLAFLLN
ECCCHHHCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TIIANLVESASKVEEILEDIEETLLDPKNDQGNMGSLIQQHRHEYMIIRKNSLPLKDQFS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHH
KLLRTENGIITPDILPIYNDLQDQLQFVIQTTESCREITSSLVDLYISNNDLRMNAIMKR
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHH
LTIVSTLFIPLTFLVGVWGMNFKIMPELDWRYGYFIAWAVMIATGVLTWLYMKRKDWY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]