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The map label for this gene is aslA [H]

Identifier: 150007798

GI number: 150007798

Start: 1339491

End: 1341017

Strand: Reverse

Name: aslA [H]

Synonym: BDI_1156

Alternate gene names: 150007798

Gene position: 1341017-1339491 (Counterclockwise)

Preceding gene: 150007799

Following gene: 150007797

Centisome position: 27.87

GC content: 48.2

Gene sequence:

>1527_bases
ATGAATAAGTATTGTATAATGAGTGTGTTGGCAGGGTTTTCCTTGCCAACAACTTTAATAGTTCAATCAGCTCCCCGGCA
ACCTAACGTGGTGATCATCGTGGCCGATGATCTCGGGTATGGTGATCTAAGCTGTTACGGGGCTCATCGCATACAGACTC
CGGGAATGGATCGTATCGCAAATGAAGGCATACGCTTTACGCAAGGTTATTGTACGGCGGCTACTTCTACCCCCAGCCGG
TATTCCTTGCTTACCGGATTATATCCTTGGACAAATAGGGATGCCAAAATACTTCCCGGCAATGCGGCTCTGATTATCAA
TACTCAACAGGTTACCTTGCCGAAGGTGATGAAGCAAGCGGGCTATGTCACCGGCTCGGTCGGCAAATGGCATCTAGGAT
TAGGTGACGGGGTGGTAGACTGGAACAAGCTGGTTTATCCCGGAGCGAAAGAGATCGGTTACGACTATTCTTTTATCCAA
GCTGCTACTAATGACCGGGTTCCCTGTATCTTTATCGAGAATGGGAGAGGTGTAAACCTCGATCCGAACGATCCTCTCTA
TGTCAGTTATAAGGAGAATTTCCCCGGGGAACCGACTGGGAAGGATAATCCTGAATTACTGAGAATGCTCCCGAGTGTCG
GGCATGCCGGCGCTATCGTAAACGGTGTACCTCGAATTGGTTTCCAGAAAGGAGGCAAGACCGCCCAATGGAAAGATGAG
GATATGGCAGAGTTGTTCCTTGAGAAGGCGAAAGGTTTTATGAAAGAGAATAAGGATAAACCTTTCTTCCTGTACTATGG
CTTGCATCAACCGCATGTACCTCGTGTTCCGAACGAGAGATTCGCGGGTAAGTCGGGGATGGGACCTCGTGGAGATGTTA
TCTTGGAAGCGGATTGGTGCGTGACCGAATTCTTGAAGGAAATGGATAAGTTGGGGCTAACGGAAAATACGTTAGTTGTT
TTCACTAGCGATAACGGACCGGTTCTGGATGACGGTTATCAAGATCAAGCCGTGGAATTGGTAGGGGATCATAAGATGGC
CGGACCGCTTCGTGGAGGAAAGACGAGCTTGTATGATGGTGGGACCTGTATCCCGTTCATGCTTCGTTGGCCTGCGGAAG
TTAAGCCGGGCGCTGTGTCGGATGCCTTGGTTTGCCAGATGGATTTGTTAGCCTCGCTGTCGGCGTTGATCGGACAGACC
TATTCTGATAAGGTAGATAGCCAAAACACCTTGCCTGTCTTCCTAGGAAAAGGTGGTAATGGGCGAAAGGAACTTGTCTT
GGAAGGTTATTTCAATTATGCGCTACGTGATGGTGATTGGGTCATGATCCCGCCGTATCCGGATACCTATGGCGACGCGG
AGGAGGCTGCCTTTGCCGGAAATAGTAACTGTTATCAATTATATAATGTAAAGGAAGACATCGGTCAGCAAGTTAATTTG
GCGGAAAAAGAACCTAAAAGACTTCGACAGATGATGATGACCTTCGAGAGGCTAAAAAGGGAAACCGGAAAGATAACGAA
CTTTTAG

Upstream 100 bases:

>100_bases
GCCTGAATATCCTGCTACCAGCCCGTTGGCTATCCAGTATATTCCGCAGTCTGAGATTAACGCTTATCCGGGTACATTAA
CTCAGAATCCGTAATAAGCG

Downstream 100 bases:

>100_bases
TCTTGGACTCTTTATTTTTCAAAATACTCAATAACGTTTTGATTGAAAAAATATTTTTTTAATTTTGTATCCTCAAAACA
CAAACTAATTTATAAAATAT

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNKYCIMSVLAGFSLPTTLIVQSAPRQPNVVIIVADDLGYGDLSCYGAHRIQTPGMDRIANEGIRFTQGYCTAATSTPSR
YSLLTGLYPWTNRDAKILPGNAALIINTQQVTLPKVMKQAGYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQ
AATNDRVPCIFIENGRGVNLDPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGAIVNGVPRIGFQKGGKTAQWKDE
DMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRVPNERFAGKSGMGPRGDVILEADWCVTEFLKEMDKLGLTENTLVV
FTSDNGPVLDDGYQDQAVELVGDHKMAGPLRGGKTSLYDGGTCIPFMLRWPAEVKPGAVSDALVCQMDLLASLSALIGQT
YSDKVDSQNTLPVFLGKGGNGRKELVLEGYFNYALRDGDWVMIPPYPDTYGDAEEAAFAGNSNCYQLYNVKEDIGQQVNL
AEKEPKRLRQMMMTFERLKRETGKITNF

Sequences:

>Translated_508_residues
MNKYCIMSVLAGFSLPTTLIVQSAPRQPNVVIIVADDLGYGDLSCYGAHRIQTPGMDRIANEGIRFTQGYCTAATSTPSR
YSLLTGLYPWTNRDAKILPGNAALIINTQQVTLPKVMKQAGYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQ
AATNDRVPCIFIENGRGVNLDPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGAIVNGVPRIGFQKGGKTAQWKDE
DMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRVPNERFAGKSGMGPRGDVILEADWCVTEFLKEMDKLGLTENTLVV
FTSDNGPVLDDGYQDQAVELVGDHKMAGPLRGGKTSLYDGGTCIPFMLRWPAEVKPGAVSDALVCQMDLLASLSALIGQT
YSDKVDSQNTLPVFLGKGGNGRKELVLEGYFNYALRDGDWVMIPPYPDTYGDAEEAAFAGNSNCYQLYNVKEDIGQQVNL
AEKEPKRLRQMMMTFERLKRETGKITNF
>Mature_508_residues
MNKYCIMSVLAGFSLPTTLIVQSAPRQPNVVIIVADDLGYGDLSCYGAHRIQTPGMDRIANEGIRFTQGYCTAATSTPSR
YSLLTGLYPWTNRDAKILPGNAALIINTQQVTLPKVMKQAGYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQ
AATNDRVPCIFIENGRGVNLDPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGAIVNGVPRIGFQKGGKTAQWKDE
DMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRVPNERFAGKSGMGPRGDVILEADWCVTEFLKEMDKLGLTENTLVV
FTSDNGPVLDDGYQDQAVELVGDHKMAGPLRGGKTSLYDGGTCIPFMLRWPAEVKPGAVSDALVCQMDLLASLSALIGQT
YSDKVDSQNTLPVFLGKGGNGRKELVLEGYFNYALRDGDWVMIPPYPDTYGDAEEAAFAGNSNCYQLYNVKEDIGQQVNL
AEKEPKRLRQMMMTFERLKRETGKITNF

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=410, Percent_Identity=29.5121951219512, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI31742482, Length=450, Percent_Identity=27.5555555555556, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI71852584, Length=445, Percent_Identity=26.9662921348315, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI45430057, Length=415, Percent_Identity=28.1927710843373, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI71852586, Length=326, Percent_Identity=27.6073619631902, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI146229331, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI146229329, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI6005990, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI146229324, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI146229327, Length=241, Percent_Identity=32.3651452282158, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI58743319, Length=118, Percent_Identity=44.9152542372881, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI157266309, Length=114, Percent_Identity=41.2280701754386, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI53831991, Length=119, Percent_Identity=38.655462184874, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI109389362, Length=524, Percent_Identity=22.1374045801527, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI38569405, Length=112, Percent_Identity=40.1785714285714, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI38569407, Length=112, Percent_Identity=40.1785714285714, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI59797060, Length=107, Percent_Identity=39.2523364485981, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1790233, Length=425, Percent_Identity=29.1764705882353, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081924, Length=533, Percent_Identity=24.765478424015, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790112, Length=128, Percent_Identity=32.03125, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533416, Length=502, Percent_Identity=22.7091633466135, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17559078, Length=297, Percent_Identity=28.2828282828283, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533418, Length=490, Percent_Identity=22.0408163265306, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666175, Length=444, Percent_Identity=25.6756756756757, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI281366397, Length=406, Percent_Identity=23.6453201970443, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281366395, Length=406, Percent_Identity=23.6453201970443, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666163, Length=406, Percent_Identity=23.6453201970443, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666109, Length=139, Percent_Identity=36.6906474820144, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281363223, Length=114, Percent_Identity=36.8421052631579, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 56010; Mature: 56010

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYCIMSVLAGFSLPTTLIVQSAPRQPNVVIIVADDLGYGDLSCYGAHRIQTPGMDRIA
CCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHH
NEGIRFTQGYCTAATSTPSRYSLLTGLYPWTNRDAKILPGNAALIINTQQVTLPKVMKQA
HCCCEEECCEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHC
GYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQAATNDRVPCIFIENGRGVNL
CCEECCCCEEEEECCCCCCCCCCEECCCHHHHCCCCCEEEECCCCCCCEEEEECCCCCCC
DPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGAIVNGVPRIGFQKGGKTAQWKDE
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCH
DMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRVPNERFAGKSGMGPRGDVILEADWC
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEEEECHHH
VTEFLKEMDKLGLTENTLVVFTSDNGPVLDDGYQDQAVELVGDHKMAGPLRGGKTSLYDG
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEECCC
GTCIPFMLRWPAEVKPGAVSDALVCQMDLLASLSALIGQTYSDKVDSQNTLPVFLGKGGN
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCC
GRKELVLEGYFNYALRDGDWVMIPPYPDTYGDAEEAAFAGNSNCYQLYNVKEDIGQQVNL
CCEEEEEEEEECEEEECCCEEEECCCCCCCCCHHHHHCCCCCCCEEEEECHHHHCCCCCC
AEKEPKRLRQMMMTFERLKRETGKITNF
CCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKYCIMSVLAGFSLPTTLIVQSAPRQPNVVIIVADDLGYGDLSCYGAHRIQTPGMDRIA
CCCHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCHHHHH
NEGIRFTQGYCTAATSTPSRYSLLTGLYPWTNRDAKILPGNAALIINTQQVTLPKVMKQA
HCCCEEECCEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHHC
GYVTGSVGKWHLGLGDGVVDWNKLVYPGAKEIGYDYSFIQAATNDRVPCIFIENGRGVNL
CCEECCCCEEEEECCCCCCCCCCEECCCHHHHCCCCCEEEECCCCCCCEEEEECCCCCCC
DPNDPLYVSYKENFPGEPTGKDNPELLRMLPSVGHAGAIVNGVPRIGFQKGGKTAQWKDE
CCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCH
DMAELFLEKAKGFMKENKDKPFFLYYGLHQPHVPRVPNERFAGKSGMGPRGDVILEADWC
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHCCCCCCCCCCCCEEEECHHH
VTEFLKEMDKLGLTENTLVVFTSDNGPVLDDGYQDQAVELVGDHKMAGPLRGGKTSLYDG
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEECCC
GTCIPFMLRWPAEVKPGAVSDALVCQMDLLASLSALIGQTYSDKVDSQNTLPVFLGKGGN
CCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCC
GRKELVLEGYFNYALRDGDWVMIPPYPDTYGDAEEAAFAGNSNCYQLYNVKEDIGQQVNL
CCEEEEEEEEECEEEECCCEEEECCCCCCCCCHHHHHCCCCCCCEEEEECHHHHCCCCCC
AEKEPKRLRQMMMTFERLKRETGKITNF
CCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]