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The map label for this gene is czcC [H]

Identifier: 150007696

GI number: 150007696

Start: 1216948

End: 1218207

Strand: Direct

Name: czcC [H]

Synonym: BDI_1051

Alternate gene names: 150007696

Gene position: 1216948-1218207 (Clockwise)

Preceding gene: 150007695

Following gene: 150007697

Centisome position: 25.29

GC content: 44.84

Gene sequence:

>1260_bases
ATGGACAGACGAGTCACTCTTTTACTTTTTTTATCTCTTCTTTTCTCTGGGGCGAAAGCCTCTGTTGTCTCCCTCTCCTT
GAAAGAGTCCGAGCAACGTTTCTCTGAACACAATCTGGAAGTGATAGCCGAACGGTATAATATCGATATAGCCGAGGCCC
AAGTAGTACAGGCCAAACTTTTCGAGAATCCCGTGGTCTCTTTGGAGCAAAATGTTTATAACCGGTTGAACGGACGTTAC
TTTGATTTCGGGAAACAAGGGGAAACGATCGTAGAGGTGGAACAGTTGATCTATATTGCCGGACAGCGAAACAAACGTGT
CCGTTTGGAGAAAATCAATAAGGAAATGGCCCTTTACCAATTCGAAGAGGTATTGAGAACCCTCCGGAGCGAGTTGAAGG
AGAAATTCATAGCGCTTTATTTCACCCAGAAATCCCAATCTATTTACGATCGTGAGATTGATTCATTGGCTCATCTGTTG
GTGGTTCTCAAGGAGCAGAATGAGAAAGGGAATGTTTCTTTATTAGAGAAGTCCCGTATCGAGGCCCTATTACTCTCTTT
ACGGCAAGAGCGGAATGATATCGCCAACCAAGTTATCTCCCTTCAAGGAGACATGCGGCTTTTACTAGGAATATCCGGCA
ATGATACCTTCGAGCCGATATTCGATGAGTCTGTGTTGAACCAGATCGATATGGACTCCGTTCCTTTCTCTGAATTGACC
TCTTTATTATACGAACGTCCGGATCTTAAGTTGGCGCAAGCAAGCGTCAAGGCTTCGGAGGCGGACGTGAGATTACAACG
TTCCCTCGCTTTCCCGGAAGTGAGCGTAAAGGGTACGTATGATAAGGCGGGTAACTTTATCAATGATTATTGGGCGATCG
GCTTGAGCGTCTCTCTCCCTATATTTAACCGGAATCAAGGGAATATCAGGGCGGCGAAAATATCCGTCGCTCAAAAGGCC
CATAAGGAAGAATACGCCCGTCGACAAGCCGAGAATGAATTATTCACCAGCTATGCCCGGTTGGAAAAGGCGATTCAGCT
TTATCGTTCCTCGAACTATGGATTGGAGAAGGATTTCGCCTTGATTATCGAAGGCGTGAACTTGAATTTCCAAAAACGGA
ATATCAGTCTCCTTGAGTTTATCGATTATTATGAGACCTACAAAACAACCTGCTTGCAACTTTACCAAACCCAAAAAGAA
GTGTTACTGGCCTTGGAGGAGGTAAACACCGTAACGGGTAGCCATGTATTCAACTATTAA

Upstream 100 bases:

>100_bases
ATCTCTCTAATAAATTTCTAATTTGGCCTAAGAGTATTCTAACTAAATATTCATAAGCGATAAAAGAGTGACTTCTACCT
TTGCGTAAAATTTAACGCAA

Downstream 100 bases:

>100_bases
AAGCAAATCAAATGATATGAATAAGCATCTAATTACATTTATCCTTTTAGTACCCTTGGTATGTTCCTGTGGGAAACAGG
CGACCACCTCGGTCGATACC

Product: cation efflux system protein CzcC

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAERYNIDIAEAQVVQAKLFENPVVSLEQNVYNRLNGRY
FDFGKQGETIVEVEQLIYIAGQRNKRVRLEKINKEMALYQFEEVLRTLRSELKEKFIALYFTQKSQSIYDREIDSLAHLL
VVLKEQNEKGNVSLLEKSRIEALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFEPIFDESVLNQIDMDSVPFSELT
SLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSVKGTYDKAGNFINDYWAIGLSVSLPIFNRNQGNIRAAKISVAQKA
HKEEYARRQAENELFTSYARLEKAIQLYRSSNYGLEKDFALIIEGVNLNFQKRNISLLEFIDYYETYKTTCLQLYQTQKE
VLLALEEVNTVTGSHVFNY

Sequences:

>Translated_419_residues
MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAERYNIDIAEAQVVQAKLFENPVVSLEQNVYNRLNGRY
FDFGKQGETIVEVEQLIYIAGQRNKRVRLEKINKEMALYQFEEVLRTLRSELKEKFIALYFTQKSQSIYDREIDSLAHLL
VVLKEQNEKGNVSLLEKSRIEALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFEPIFDESVLNQIDMDSVPFSELT
SLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSVKGTYDKAGNFINDYWAIGLSVSLPIFNRNQGNIRAAKISVAQKA
HKEEYARRQAENELFTSYARLEKAIQLYRSSNYGLEKDFALIIEGVNLNFQKRNISLLEFIDYYETYKTTCLQLYQTQKE
VLLALEEVNTVTGSHVFNY
>Mature_419_residues
MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAERYNIDIAEAQVVQAKLFENPVVSLEQNVYNRLNGRY
FDFGKQGETIVEVEQLIYIAGQRNKRVRLEKINKEMALYQFEEVLRTLRSELKEKFIALYFTQKSQSIYDREIDSLAHLL
VVLKEQNEKGNVSLLEKSRIEALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFEPIFDESVLNQIDMDSVPFSELT
SLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSVKGTYDKAGNFINDYWAIGLSVSLPIFNRNQGNIRAAKISVAQKA
HKEEYARRQAENELFTSYARLEKAIQLYRSSNYGLEKDFALIIEGVNLNFQKRNISLLEFIDYYETYKTTCLQLYQTQKE
VLLALEEVNTVTGSHVFNY

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 48210; Mature: 48210

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAERYNIDIAEAQVVQAKL
CCCHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FENPVVSLEQNVYNRLNGRYFDFGKQGETIVEVEQLIYIAGQRNKRVRLEKINKEMALYQ
HCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FEEVLRTLRSELKEKFIALYFTQKSQSIYDREIDSLAHLLVVLKEQNEKGNVSLLEKSRI
HHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
EALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFEPIFDESVLNQIDMDSVPFSELT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHH
SLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSVKGTYDKAGNFINDYWAIGLSVSLP
HHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEECCCHHHHCCHHHHHHEEEEEEEEE
IFNRNQGNIRAAKISVAQKAHKEEYARRQAENELFTSYARLEKAIQLYRSSNYGLEKDFA
EEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LIIEGVNLNFQKRNISLLEFIDYYETYKTTCLQLYQTQKEVLLALEEVNTVTGSHVFNY
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDRRVTLLLFLSLLFSGAKASVVSLSLKESEQRFSEHNLEVIAERYNIDIAEAQVVQAKL
CCCHHHHHHHHHHHHCCCCHHEEEEEHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHH
FENPVVSLEQNVYNRLNGRYFDFGKQGETIVEVEQLIYIAGQRNKRVRLEKINKEMALYQ
HCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FEEVLRTLRSELKEKFIALYFTQKSQSIYDREIDSLAHLLVVLKEQNEKGNVSLLEKSRI
HHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
EALLLSLRQERNDIANQVISLQGDMRLLLGISGNDTFEPIFDESVLNQIDMDSVPFSELT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHH
SLLYERPDLKLAQASVKASEADVRLQRSLAFPEVSVKGTYDKAGNFINDYWAIGLSVSLP
HHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCEEECCCHHHHCCHHHHHHEEEEEEEEE
IFNRNQGNIRAAKISVAQKAHKEEYARRQAENELFTSYARLEKAIQLYRSSNYGLEKDFA
EEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LIIEGVNLNFQKRNISLLEFIDYYETYKTTCLQLYQTQKEVLLALEEVNTVTGSHVFNY
EEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]