Click here to switch to the map view.

The map label for this gene is pstP [H]

Identifier: 150007682

GI number: 150007682

Start: 1200796

End: 1201599

Strand: Direct

Name: pstP [H]

Synonym: BDI_1037

Alternate gene names: 150007682

Gene position: 1200796-1201599 (Clockwise)

Preceding gene: 150007681

Following gene: 150007683

Centisome position: 24.96

GC content: 42.41

Gene sequence:

>804_bases
ATGATTATAACGATCGGTAAGCCATGTGCTATTACGGAAAAAGGAGGCAGATCGAATAACGAGGATTCCATTTACCCGCT
TCCCGAACAAGTGACCCTTGACCAAAAATTGTTTATGGTTTGCGATGGTGTGGGTGGAGCCGAGAAAGGGGAGGTAGCCA
GCTCATTAGCTTGCGAGTCCATACAAACTTTCTTTTCTACGTTCCTAAAGGATGATCCCACGCCAGAGTTTATCCATAAA
GCCGTACATTATGCGGAAGTCTGTTTCGACTCCTATGTTCAAGAGCATCCGGAAGCGATGGGTATGGCTACTACGCTCAC
CATGGCCTATATCGCTTCTTCCGGAATCGTATTGGCTCATATCGGAGATAGCCGGATCTATCATCTGAGGAAGGGGGAGA
TTTTATATCAAACAGAAGATCATTCATTGGTAAATTCGTTGGTTAAATTAGGTAAGATCACTCCGGAAGAAGCGTTAACC
CACCCCCAGCGGAATGTGATTATCCGGGCTATACAAGGCACTCATACTCCAACAGAAGCGGACATTATTACCTTGAACGA
TATTCAACCCGACGATTTCCTCTTTCTTTGTACGGACGGGGTTCTTGAAAGACTGAAGAATGAAAAGATTGCAGAGATAT
TTAATGGTCGTTTATCTGTTCCGGAAATAAAGGACGCTCTCATGGAAGCCTGTGACGGCAAGACTCGGGATAATTTTTCT
TTTTATATCATAACTATTCAAAAAGTGGAAGATAGCATGGGTTTTAAGCAAAATATTCTCTCTTTTCTTTATTCTTTTAT
ATAA

Upstream 100 bases:

>100_bases
CAGTTACCTAGAGAATGGCGAGGTGGTCGTGCTCAATGATAATGACGAGATTATTATTGGTCGCACCGTCTTACGTTTTA
ATGAATAAAACTCATTTGTT

Downstream 100 bases:

>100_bases
ATAACGTACTTTTGGCAGATTAAATGGAATTATTCAAGGTTATGAATCTGCCAGACGGACATCTTCTTCAAAACGGAAAA
TACAGACTTACTCATGTGGT

Product: putative serine/threonine phosphatase

Products: NA

Alternate protein names: Mycobacterial Ser/Thr phosphatase; Mstp; Possible serine/threonine phosphatase Ppp [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGVGGAEKGEVASSLACESIQTFFSTFLKDDPTPEFIHK
AVHYAEVCFDSYVQEHPEAMGMATTLTMAYIASSGIVLAHIGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALT
HPQRNVIIRAIQGTHTPTEADIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRLSVPEIKDALMEACDGKTRDNFS
FYIITIQKVEDSMGFKQNILSFLYSFI

Sequences:

>Translated_267_residues
MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGVGGAEKGEVASSLACESIQTFFSTFLKDDPTPEFIHK
AVHYAEVCFDSYVQEHPEAMGMATTLTMAYIASSGIVLAHIGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALT
HPQRNVIIRAIQGTHTPTEADIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRLSVPEIKDALMEACDGKTRDNFS
FYIITIQKVEDSMGFKQNILSFLYSFI
>Mature_267_residues
MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGVGGAEKGEVASSLACESIQTFFSTFLKDDPTPEFIHK
AVHYAEVCFDSYVQEHPEAMGMATTLTMAYIASSGIVLAHIGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALT
HPQRNVIIRAIQGTHTPTEADIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRLSVPEIKDALMEACDGKTRDNFS
FYIITIQKVEDSMGFKQNILSFLYSFI

Specific function: The only predicted protein phosphatase in M.tuberculosis, it dephosphorylates at least 5 protein kinases (pknA, pknB, pknD, pknE and pknF) and the penicillin-binding protein PBPA [H]

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=May be localized to the outside of the cell [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 29747; Mature: 29747

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGVGGAEKGEVASSLACES
CEEECCCCEEEECCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHH
IQTFFSTFLKDDPTPEFIHKAVHYAEVCFDSYVQEHPEAMGMATTLTMAYIASSGIVLAH
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEE
IGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALTHPQRNVIIRAIQGTHTPTEA
ECCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHCCCCHHEEEEEECCCCCCCCC
DIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRLSVPEIKDALMEACDGKTRDNFS
EEEEECCCCCCCEEEEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEE
FYIITIQKVEDSMGFKQNILSFLYSFI
EEEEEEEECHHHCCHHHHHHHHHHHHC
>Mature Secondary Structure
MIITIGKPCAITEKGGRSNNEDSIYPLPEQVTLDQKLFMVCDGVGGAEKGEVASSLACES
CEEECCCCEEEECCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHH
IQTFFSTFLKDDPTPEFIHKAVHYAEVCFDSYVQEHPEAMGMATTLTMAYIASSGIVLAH
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEE
IGDSRIYHLRKGEILYQTEDHSLVNSLVKLGKITPEEALTHPQRNVIIRAIQGTHTPTEA
ECCCEEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHCCCCHHEEEEEECCCCCCCCC
DIITLNDIQPDDFLFLCTDGVLERLKNEKIAEIFNGRLSVPEIKDALMEACDGKTRDNFS
EEEEECCCCCCCEEEEECHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEE
FYIITIQKVEDSMGFKQNILSFLYSFI
EEEEEEEECHHHCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]