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The map label for this gene is mltF [H]

Identifier: 150007674

GI number: 150007674

Start: 1191156

End: 1192541

Strand: Reverse

Name: mltF [H]

Synonym: BDI_1029

Alternate gene names: 150007674

Gene position: 1192541-1191156 (Counterclockwise)

Preceding gene: 150007675

Following gene: 150007672

Centisome position: 24.79

GC content: 44.37

Gene sequence:

>1386_bases
ATGTATAGGAAATACGTCCCCTTTCTGCTCTTTTTGTTCTTCTTGTATGGTTGCAACGGTAACAAACAAGAGGAGAAAGA
GGACGTTTCCGTTTTCGTGGATTTACCGCAACTGAAAGCGGAAGGCGAGATCACGGCGGTGACTTTATACAGTTCTACCT
CCTACTTCCAATATAAGATGCAACCCATGGGTTACGAATACGATCTGATAAACGATTTTGCCAAGAGCCAAGGTTTGAAA
TTAAACATCAAGGTCGCCGAGAATCCTGCCCGTCTGATCGAGATGCTAGAAGCCGGCGAGGTCGATGTTGTAGCCTACCC
TATCCCAATCAATAACAAGCTGAAACAAGAGGTCATTTATTGCGGCCGGGAGGATATCTCCAGTCAAGTATTGATACAAC
GGGCCAATAAAGGCGATAAGCTTCTTACCGATGTCACTCAATTAATCGATAAGAATGTTTACGTAAAGCCTAACACCAAA
TACTCCGAACGACTGAAGAACTTGGATGAGGAACTCGGCGGAGGAATCCATATCCAAAAAGTGGAAAATGACTCCATTGC
TACCGAAGATCTTATCGAGATGGTCTCCTTGGGCGAAATTCCCTATACGATCAGCGATGATAACACCGCCCGCCTAAACA
AGACTTATTATTGGAATATCAATGTCGACCTAAAGGTTAGTTTTCCCCAACGTTCTTCATGGGTGGTAAGGAAAAGTAGT
CCGGACTTGGCGAAGGCGATCGATGAATGGGCTTCCGATAAAACGGGTAAACATTCTTTCAAGGCAGTTACTAAGCGGTA
CTTTGAATTAAGCAAGCAACCTTTTACCGCAGATATTCCGGAGGTAAAGAATGGACATATTTCCCCGTATGACCCTTTAT
TCAAGAAACATGCGAAAAACATCGGATGGGATTGGCAGCTGCTGGCGTCTATTTCCTATCAAGAGTCTCATTTCAATCCT
ACGGTTGTATCGTGGGCCGGTGCCGAGGGGCTTATGGGAATCATGCCAAATACGGCGAAGGCATTAGGTGTCACCCCGCA
TGAATTGAAAGATCCGGATACGGGAATCCGTACGGGAGTAGATTGTTTACGGCGCTTCCGTCAAGGTTTTTCTGAGATTA
CGGATCCTGAAGAAAAAGTCAAGTTTACCCTAGCGGCTTACAACGCTGGGATCGGACATATTTACGATGCGCAGCGATTG
GCCCGAAAATATGGAAAAGATCCCAATAAATGGGATAATAATGTAGCGGAATATATTCGTTTGAAAAATGATCCCGAGTA
TTATAACGATCCTGTTTGCAAGCATGGATACTTGCGTGGCTCAGAAACATATAATTACGTGCGGGAAGTGTTGGAGCGTT
ATCATTACTACAAGAAAAAGTCATAG

Upstream 100 bases:

>100_bases
GAAATACTCCGTCAAGAAAGTCCGTCCGGTCGATATGTTTCCTCATACACATCATGTGGAGAACGTGGTTTTGCTTGAGA
AAAAATAAACATATAATATA

Downstream 100 bases:

>100_bases
TTATAAAAAAATTCATAGCTATGAGTGAAAGTAGTCATAACTATGAATTTTCTGCAAGTAAATGCCACTTAAAAATTATA
GGCGACACCTATGCCTAATA

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEITAVTLYSSTSYFQYKMQPMGYEYDLINDFAKSQGLK
LNIKVAENPARLIEMLEAGEVDVVAYPIPINNKLKQEVIYCGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTK
YSERLKNLDEELGGGIHIQKVENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYWNINVDLKVSFPQRSSWVVRKSS
PDLAKAIDEWASDKTGKHSFKAVTKRYFELSKQPFTADIPEVKNGHISPYDPLFKKHAKNIGWDWQLLASISYQESHFNP
TVVSWAGAEGLMGIMPNTAKALGVTPHELKDPDTGIRTGVDCLRRFRQGFSEITDPEEKVKFTLAAYNAGIGHIYDAQRL
ARKYGKDPNKWDNNVAEYIRLKNDPEYYNDPVCKHGYLRGSETYNYVREVLERYHYYKKKS

Sequences:

>Translated_461_residues
MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEITAVTLYSSTSYFQYKMQPMGYEYDLINDFAKSQGLK
LNIKVAENPARLIEMLEAGEVDVVAYPIPINNKLKQEVIYCGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTK
YSERLKNLDEELGGGIHIQKVENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYWNINVDLKVSFPQRSSWVVRKSS
PDLAKAIDEWASDKTGKHSFKAVTKRYFELSKQPFTADIPEVKNGHISPYDPLFKKHAKNIGWDWQLLASISYQESHFNP
TVVSWAGAEGLMGIMPNTAKALGVTPHELKDPDTGIRTGVDCLRRFRQGFSEITDPEEKVKFTLAAYNAGIGHIYDAQRL
ARKYGKDPNKWDNNVAEYIRLKNDPEYYNDPVCKHGYLRGSETYNYVREVLERYHYYKKKS
>Mature_461_residues
MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEITAVTLYSSTSYFQYKMQPMGYEYDLINDFAKSQGLK
LNIKVAENPARLIEMLEAGEVDVVAYPIPINNKLKQEVIYCGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTK
YSERLKNLDEELGGGIHIQKVENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYWNINVDLKVSFPQRSSWVVRKSS
PDLAKAIDEWASDKTGKHSFKAVTKRYFELSKQPFTADIPEVKNGHISPYDPLFKKHAKNIGWDWQLLASISYQESHFNP
TVVSWAGAEGLMGIMPNTAKALGVTPHELKDPDTGIRTGVDCLRRFRQGFSEITDPEEKVKFTLAAYNAGIGHIYDAQRL
ARKYGKDPNKWDNNVAEYIRLKNDPEYYNDPVCKHGYLRGSETYNYVREVLERYHYYKKKS

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=445, Percent_Identity=27.6404494382022, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 52945; Mature: 52945

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEITAVTLYSSTSYFQYKM
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCEEEEEE
QPMGYEYDLINDFAKSQGLKLNIKVAENPARLIEMLEAGEVDVVAYPIPINNKLKQEVIY
CCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
CGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTKYSERLKNLDEELGGGIHIQK
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCEEEEE
VENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYWNINVDLKVSFPQRSSWVVRKSS
ECCCCCCHHHHHHHHHHCCCCEEECCCCCEEECEEEEEEEEEEEEEECCCCCCEEEECCC
PDLAKAIDEWASDKTGKHSFKAVTKRYFELSKQPFTADIPEVKNGHISPYDPLFKKHAKN
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
IGWDWQLLASISYQESHFNPTVVSWAGAEGLMGIMPNTAKALGVTPHELKDPDTGIRTGV
CCCCEEEEEEECHHHCCCCCCEEEECCCCCCEECCCCCHHHCCCCHHHCCCCCCHHHHHH
DCLRRFRQGFSEITDPEEKVKFTLAAYNAGIGHIYDAQRLARKYGKDPNKWDNNVAEYIR
HHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
LKNDPEYYNDPVCKHGYLRGSETYNYVREVLERYHYYKKKS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYRKYVPFLLFLFFLYGCNGNKQEEKEDVSVFVDLPQLKAEGEITAVTLYSSTSYFQYKM
CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECCCEEEEEE
QPMGYEYDLINDFAKSQGLKLNIKVAENPARLIEMLEAGEVDVVAYPIPINNKLKQEVIY
CCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHH
CGREDISSQVLIQRANKGDKLLTDVTQLIDKNVYVKPNTKYSERLKNLDEELGGGIHIQK
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCEEEEE
VENDSIATEDLIEMVSLGEIPYTISDDNTARLNKTYYWNINVDLKVSFPQRSSWVVRKSS
ECCCCCCHHHHHHHHHHCCCCEEECCCCCEEECEEEEEEEEEEEEEECCCCCCEEEECCC
PDLAKAIDEWASDKTGKHSFKAVTKRYFELSKQPFTADIPEVKNGHISPYDPLFKKHAKN
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
IGWDWQLLASISYQESHFNPTVVSWAGAEGLMGIMPNTAKALGVTPHELKDPDTGIRTGV
CCCCEEEEEEECHHHCCCCCCEEEECCCCCCEECCCCCHHHCCCCHHHCCCCCCHHHHHH
DCLRRFRQGFSEITDPEEKVKFTLAAYNAGIGHIYDAQRLARKYGKDPNKWDNNVAEYIR
HHHHHHHHHHHHCCCCHHHHEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
LKNDPEYYNDPVCKHGYLRGSETYNYVREVLERYHYYKKKS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA