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The map label for this gene is phoR [H]

Identifier: 150007638

GI number: 150007638

Start: 1155143

End: 1157080

Strand: Direct

Name: phoR [H]

Synonym: BDI_0991

Alternate gene names: 150007638

Gene position: 1155143-1157080 (Clockwise)

Preceding gene: 150007637

Following gene: 150007640

Centisome position: 24.01

GC content: 49.59

Gene sequence:

>1938_bases
ATGATTGGTCTTGTTAAATACGTAGGAAATCACTCTTTGTATATAAAGCATTTTTGTTTTATATGCATTTTATTGATGTG
GATACTCTCGCTGATACCTTCTTGTCATCGAGAGGGAGAGGTTGGTCTTTCCCAAAATGATCAGGTGGGTATAGATAGTG
TGGTCTCGGCCTGTCCGGACATCGATTCTCTACAATCATGCCTAAGGTATTTCGAGAGAACCGCAAATGAGCTGGGAGTG
ATACTCGCCTATAAGGAATTAGGGGTACGTTACCGGGAAGCGGCCCGTTTTAATGAGGCGATAGGATGCCACCGGGAAGG
CTTGCGATTGGCTATGCAACGGAAAGATACCTCGGAGGTCATACAGGCCTTGAATAATATCGGTACGAACTTCCGGCGGT
TAGGTATCATGGACGAGGCCTCCAATTATCATTATAGGGCATTGTCGTTGTGCGAGAGACTGGGCGATAAGGAAAGCTAT
AAGGCAAGAAAAAACCGGACCATTTCCTTGAGTGGTATCGGAAACGTGTATCTAACATTGGAAAATTGCGAGATGGCCGA
CAGTATTTTCCGAATAGCGCTGGAAGAGGAACGTACCTTGGACAGTGATCTCGGCTTGGCCATGAACTACGCGAACCTTG
GCTCTATCTTCGAGATGCGTGGCATGATGGATTCCGCTTTTGTTTATTACAATTATTCTATGGAGCATAATCGTGCGGCC
GGGTCTGTTGTCGGCATCTCGCTTTGCCATAACCATATAGGACGCTTGTTCGAGAAAAAGGGACAATGGGATCAGGCGAT
ACGCGAATATCGTAACGCATACGACCTTATGGTAGCGGACAACGATCTGTATCATTGGCTGGAATCGTGCCTGGCCTTGG
CACGGGTGAATATCTACAAGGGAGATCTGCGAATGGCGGAGGCTTTTTTGGAGCATGCGGAGGGTGCCGCTAAGGTGACG
CGGGCGTGGAAGCATTTGTCGAGCGTGTATCATCTGGATTACTTGCGTTATGAGAAGCTGGGTGATTATAAGAATGCCCT
CAACGCTTATACATCAAGTCTCGCTTATGCTGATAGCATGCGAAATACTGAGAATATGAACCATATACAGAACCTCCGTG
TGGACTACGAGAAAGAGAGGAGCAACCGGGAGCTTTCATTGATACAGAAGAATTATGAGATGGGGCAGCGTACCAAGAAT
ATTTTCCTGATCGCTTGCTTGATCGTACTCTTCCTTACGGTGGTAGCGATGGGCTTTTTATGGTATGCCTTGCGGATGAA
GTCCCGCAATCAGCAGGTGATGCGGCGCATGGAGGAGGTGAGGGCCAATTTCTTCACGAATGTCACGCATGAGTTTCGTA
CGCCGCTGACGGTTATCTTGGGTGTGTCGGAAGAGTTGCGGAAAGGGGGAATAGGCGAGGAGGAACTCAAGACCGGGCTG
AATATGATTGGACGGCAGGGAAAGAACCTGCTGGAATTGGTGAACCAATTATTGGAAGTGGCGAAAGTGAGATCTGAGAT
TGGCGATCCGGAATGGAGGACTGGAGATATCGTAGCTTATACGAGCATGATCGTGGAAGATAACCGGGCGTATGCCCGCC
AAGGGCAGGTAGACCTTTGTTTTACTCCTTCGGAGACGATTATCAGCATGGATTTCGTGCCCGAGTATTTCCGGAGGATC
ATGGATAACTTACTCCGCAACGCTATCAAGTTCACGCCGAGAGGTGGGAGGGTTGTCGTGACGATGGAGTGTGTGGGGAG
TATGCTTGTCACGCATGTGGCGGATACGGGCTGCGGTATAGCCGAGGAGGACTTGCCGCATATCTTCAAGGCTTTTTACC
TAGGTGAGACCGGAGGGGCAGGCACGATGGGCACGGGGGTCGGCCTTTCTTTGGTACGGCAGATGGTGAGGAGCATGGAG
GGCCGGGGTTGGTTCTGA

Upstream 100 bases:

>100_bases
TCGGACTTCTCTAAACATCTTGTTTTAGGTGATTCGGGAAATAAACACTCTCTTTGCGGTATCGATTGAATCTCTTTGTT
TACTTCTGAAAGTATTTGTG

Downstream 100 bases:

>100_bases
GTTTGTCGTGATGTTGCCATTGAGACATGGCGACTCTTATTATATCGGCCGGCTGCTTAATGGTGCGTATCAAATAGTAT
ACGCACGAAATGGAGCGGAG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MIGLVKYVGNHSLYIKHFCFICILLMWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPDIDSLQSCLRYFERTANELGV
ILAYKELGVRYREAARFNEAIGCHREGLRLAMQRKDTSEVIQALNNIGTNFRRLGIMDEASNYHYRALSLCERLGDKESY
KARKNRTISLSGIGNVYLTLENCEMADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAA
GSVVGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYKGDLRMAEAFLEHAEGAAKVT
RAWKHLSSVYHLDYLRYEKLGDYKNALNAYTSSLAYADSMRNTENMNHIQNLRVDYEKERSNRELSLIQKNYEMGQRTKN
IFLIACLIVLFLTVVAMGFLWYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEELKTGL
NMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYARQGQVDLCFTPSETIISMDFVPEYFRRI
MDNLLRNAIKFTPRGGRVVVTMECVGSMLVTHVADTGCGIAEEDLPHIFKAFYLGETGGAGTMGTGVGLSLVRQMVRSME
GRGWF

Sequences:

>Translated_645_residues
MIGLVKYVGNHSLYIKHFCFICILLMWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPDIDSLQSCLRYFERTANELGV
ILAYKELGVRYREAARFNEAIGCHREGLRLAMQRKDTSEVIQALNNIGTNFRRLGIMDEASNYHYRALSLCERLGDKESY
KARKNRTISLSGIGNVYLTLENCEMADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAA
GSVVGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYKGDLRMAEAFLEHAEGAAKVT
RAWKHLSSVYHLDYLRYEKLGDYKNALNAYTSSLAYADSMRNTENMNHIQNLRVDYEKERSNRELSLIQKNYEMGQRTKN
IFLIACLIVLFLTVVAMGFLWYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEELKTGL
NMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYARQGQVDLCFTPSETIISMDFVPEYFRRI
MDNLLRNAIKFTPRGGRVVVTMECVGSMLVTHVADTGCGIAEEDLPHIFKAFYLGETGGAGTMGTGVGLSLVRQMVRSME
GRGWF
>Mature_645_residues
MIGLVKYVGNHSLYIKHFCFICILLMWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPDIDSLQSCLRYFERTANELGV
ILAYKELGVRYREAARFNEAIGCHREGLRLAMQRKDTSEVIQALNNIGTNFRRLGIMDEASNYHYRALSLCERLGDKESY
KARKNRTISLSGIGNVYLTLENCEMADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAA
GSVVGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYKGDLRMAEAFLEHAEGAAKVT
RAWKHLSSVYHLDYLRYEKLGDYKNALNAYTSSLAYADSMRNTENMNHIQNLRVDYEKERSNRELSLIQKNYEMGQRTKN
IFLIACLIVLFLTVVAMGFLWYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEELKTGL
NMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYARQGQVDLCFTPSETIISMDFVPEYFRRI
MDNLLRNAIKFTPRGGRVVVTMECVGSMLVTHVADTGCGIAEEDLPHIFKAFYLGETGGAGTMGTGVGLSLVRQMVRSME
GRGWF

Specific function: Member of the two-component regulatory system phoP/phoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates phoP in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Homo sapiens, GI224028289, Length=326, Percent_Identity=21.7791411042945, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=212, Percent_Identity=26.4150943396226, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=237, Percent_Identity=29.535864978903, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693157, Length=217, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=214, Percent_Identity=26.6355140186916, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=26.9565217391304, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=25.1046025104602, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081816, Length=217, Percent_Identity=25.3456221198157, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660950, Length=309, Percent_Identity=23.3009708737864, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73487; Mature: 73487

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50293 TPR_REGION ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLVKYVGNHSLYIKHFCFICILLMWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPD
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCC
IDSLQSCLRYFERTANELGVILAYKELGVRYREAARFNEAIGCHREGLRLAMQRKDTSEV
HHHHHHHHHHHHHHHHHHHEEEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
IQALNNIGTNFRRLGIMDEASNYHYRALSLCERLGDKESYKARKNRTISLSGIGNVYLTL
HHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCEEEEEE
ENCEMADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAA
ECCHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCHHCEEEEEEECCCCCCCC
GSVVGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYK
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEEECCHHHHHHHHHHHHHHHHHHH
GDLRMAEAFLEHAEGAAKVTRAWKHLSSVYHLDYLRYEKLGDYKNALNAYTSSLAYADSM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTENMNHIQNLRVDYEKERSNRELSLIQKNYEMGQRTKNIFLIACLIVLFLTVVAMGFL
CCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEELKTGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCHHHHHCCCCHHHHHHHH
NMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYARQGQVDLC
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEE
FTPSETIISMDFVPEYFRRIMDNLLRNAIKFTPRGGRVVVTMECVGSMLVTHVADTGCGI
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCC
AEEDLPHIFKAFYLGETGGAGTMGTGVGLSLVRQMVRSMEGRGWF
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIGLVKYVGNHSLYIKHFCFICILLMWILSLIPSCHREGEVGLSQNDQVGIDSVVSACPD
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCC
IDSLQSCLRYFERTANELGVILAYKELGVRYREAARFNEAIGCHREGLRLAMQRKDTSEV
HHHHHHHHHHHHHHHHHHHEEEEHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
IQALNNIGTNFRRLGIMDEASNYHYRALSLCERLGDKESYKARKNRTISLSGIGNVYLTL
HHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCEEEEECCCEEEEEE
ENCEMADSIFRIALEEERTLDSDLGLAMNYANLGSIFEMRGMMDSAFVYYNYSMEHNRAA
ECCHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCHHCEEEEEEECCCCCCCC
GSVVGISLCHNHIGRLFEKKGQWDQAIREYRNAYDLMVADNDLYHWLESCLALARVNIYK
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHEEEEECCHHHHHHHHHHHHHHHHHHH
GDLRMAEAFLEHAEGAAKVTRAWKHLSSVYHLDYLRYEKLGDYKNALNAYTSSLAYADSM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNTENMNHIQNLRVDYEKERSNRELSLIQKNYEMGQRTKNIFLIACLIVLFLTVVAMGFL
CCCCHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WYALRMKSRNQQVMRRMEEVRANFFTNVTHEFRTPLTVILGVSEELRKGGIGEEELKTGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCHHHHHCCCCHHHHHHHH
NMIGRQGKNLLELVNQLLEVAKVRSEIGDPEWRTGDIVAYTSMIVEDNRAYARQGQVDLC
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCEEEE
FTPSETIISMDFVPEYFRRIMDNLLRNAIKFTPRGGRVVVTMECVGSMLVTHVADTGCGI
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHHHHHHHHHHHCCCCC
AEEDLPHIFKAFYLGETGGAGTMGTGVGLSLVRQMVRSMEGRGWF
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3142862; 9387221; 9384377 [H]