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The map label for this gene is mdtE [H]

Identifier: 150007620

GI number: 150007620

Start: 1131508

End: 1132617

Strand: Reverse

Name: mdtE [H]

Synonym: BDI_0973

Alternate gene names: 150007620

Gene position: 1132617-1131508 (Counterclockwise)

Preceding gene: 150007622

Following gene: 150007619

Centisome position: 23.54

GC content: 47.3

Gene sequence:

>1110_bases
ATGAAAAAGCAAAATCGATTGATGAAGACTGCGATCGCCTTATGGTGTATCGTAGCTGTTGGGTGTAAACAAAGCCCTGT
AATCCAACAAAGTTCAGGGTATACGACAATGACCGTATTCACTTCGGAGAAAACTTTATCCAATAATTACTCGGCGAGTA
TACGAGGAAAACAGGACATCGATATTTATCCGCAAGTATCCGGCTTTATTACAAAGCTCTGCGTAACGGAAGGCGAGAGT
GTAAAAAAAGGACAAGTCTTATTTATTATTGATCAAGTTCCTTATCAAGCGGCCTTAAACACCGCCATTGCGAACGTAGA
GGCCGCTAAGGCATCTGTAGCGACAGCGCAACTGACCTACGACAGTAAACAAGAATTGTATAAAAACAAAGTAGTTTCCG
AGTTCGACCTAAAGACCGCCTACAACACTCTACTCTCGGCAAAAGCCCAATTAGCCCAAGCGGAGGCACAAGAGATAAAC
GCCCGTAACAACCTTTCTTACACGGAAGTGAAAAGCCCCTCGAACGGCGTCATCGGAACCCTGCCTTATCGTGTAGGCGC
ATTAGTAAGCGCAAACCTGCCCAAACCGCTCACCACGGTATCGGACAATTCCGAGATGTATGTGTATTTCTCCATGACCG
AGAATCAGCTATTGGCCTTGACCCGTCAATACGGCTCGAAAGACAAAGCCTTGGAGAATATGCCCGAGATAGAGCTTCAA
CTGAACGATAAATCGCTTTATCCCCAAACGGGAAAGATCGAGACGATCAGCGGCATTATCGATCAAAACACCGGAACAGT
CAGCTTGCGTGCCGCATTCCCGAACGAGGAGCAATTATTGAATAGCGGGGGCTCCGGGAATGTGATCATTCCGGTTACAT
ACGATAACTGCGTCGTAATTCCCCAAGCCGCCACGTTCGAGATCCAAGACCGGGTATTTGTCTTCAAGGTAGTGGACGGC
AAGACGCAATCCGCCCCCGTAGAAGTGACCCGTGTGAACGGAGGACAAGAGTATATCGTAAACGCCGGATTGAATAGCGG
CGACGTGATCGTAGCCGAAGGCGTAGGTTTATTGCGTGAAGGAACACCGATTGAAGTAAAACAAAATTAA

Upstream 100 bases:

>100_bases
TCATTCCATCTCAAAATGAACAATCATCGCCTCATTGTGGAAACAATGGTTCGCCGATAAGCGAGTAGCTTTGCATCCGA
AAATATAGGTATTAGTTAAG

Downstream 100 bases:

>100_bases
GAACAATGAAAGTTAGCACATTTATAGAACGCCCCGTACTGTCCGCCGTAATTTCCATCACGATTATGGTTGCGGGTATC
ATCGGGCTTTTCACCTTGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYTTMTVFTSEKTLSNNYSASIRGKQDIDIYPQVSGFITKLCVTEGES
VKKGQVLFIIDQVPYQAALNTAIANVEAAKASVATAQLTYDSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEIN
ARNNLSYTEVKSPSNGVIGTLPYRVGALVSANLPKPLTTVSDNSEMYVYFSMTENQLLALTRQYGSKDKALENMPEIELQ
LNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNEEQLLNSGGSGNVIIPVTYDNCVVIPQAATFEIQDRVFVFKVVDG
KTQSAPVEVTRVNGGQEYIVNAGLNSGDVIVAEGVGLLREGTPIEVKQN

Sequences:

>Translated_369_residues
MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYTTMTVFTSEKTLSNNYSASIRGKQDIDIYPQVSGFITKLCVTEGES
VKKGQVLFIIDQVPYQAALNTAIANVEAAKASVATAQLTYDSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEIN
ARNNLSYTEVKSPSNGVIGTLPYRVGALVSANLPKPLTTVSDNSEMYVYFSMTENQLLALTRQYGSKDKALENMPEIELQ
LNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNEEQLLNSGGSGNVIIPVTYDNCVVIPQAATFEIQDRVFVFKVVDG
KTQSAPVEVTRVNGGQEYIVNAGLNSGDVIVAEGVGLLREGTPIEVKQN
>Mature_369_residues
MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYTTMTVFTSEKTLSNNYSASIRGKQDIDIYPQVSGFITKLCVTEGES
VKKGQVLFIIDQVPYQAALNTAIANVEAAKASVATAQLTYDSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEIN
ARNNLSYTEVKSPSNGVIGTLPYRVGALVSANLPKPLTTVSDNSEMYVYFSMTENQLLALTRQYGSKDKALENMPEIELQ
LNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNEEQLLNSGGSGNVIIPVTYDNCVVIPQAATFEIQDRVFVFKVVDG
KTQSAPVEVTRVNGGQEYIVNAGLNSGDVIVAEGVGLLREGTPIEVKQN

Specific function: Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=305, Percent_Identity=31.4754098360656, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786668, Length=316, Percent_Identity=29.1139240506329, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1789665, Length=309, Percent_Identity=28.8025889967638, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082036, Length=309, Percent_Identity=24.9190938511327, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87081951, Length=163, Percent_Identity=31.9018404907975, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081796, Length=364, Percent_Identity=27.7472527472527, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789637, Length=182, Percent_Identity=32.967032967033, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40061; Mature: 40061

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYTTMTVFTSEKTLSNNYSASIRGKQDI
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCCCC
DIYPQVSGFITKLCVTEGESVKKGQVLFIIDQVPYQAALNTAIANVEAAKASVATAQLTY
EECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHEEEEEEEEC
DSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEINARNNLSYTEVKSPSNGVIGT
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEE
LPYRVGALVSANLPKPLTTVSDNSEMYVYFSMTENQLLALTRQYGSKDKALENMPEIELQ
CCHHCCEEEECCCCCCCEEECCCCEEEEEEEECCCCEEHHHHHHCCCCHHHHCCCCEEEE
LNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNEEQLLNSGGSGNVIIPVTYDNCVVI
ECCCCCCCCCCCEEEEEHEEECCCCEEEEEEECCCHHHHHHCCCCCCEEEEEECCCEEEE
PQAATFEIQDRVFVFKVVDGKTQSAPVEVTRVNGGQEYIVNAGLNSGDVIVAEGVGLLRE
CCCCEEEEECEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCCCCC
GTPIEVKQN
CCCEEEECC
>Mature Secondary Structure
MKKQNRLMKTAIALWCIVAVGCKQSPVIQQSSGYTTMTVFTSEKTLSNNYSASIRGKQDI
CCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEEECCCCCCCCCEEEECCCCCC
DIYPQVSGFITKLCVTEGESVKKGQVLFIIDQVPYQAALNTAIANVEAAKASVATAQLTY
EECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHEEEEEEEEC
DSKQELYKNKVVSEFDLKTAYNTLLSAKAQLAQAEAQEINARNNLSYTEVKSPSNGVIGT
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEE
LPYRVGALVSANLPKPLTTVSDNSEMYVYFSMTENQLLALTRQYGSKDKALENMPEIELQ
CCHHCCEEEECCCCCCCEEECCCCEEEEEEEECCCCEEHHHHHHCCCCHHHHCCCCEEEE
LNDKSLYPQTGKIETISGIIDQNTGTVSLRAAFPNEEQLLNSGGSGNVIIPVTYDNCVVI
ECCCCCCCCCCCEEEEEHEEECCCCEEEEEEECCCHHHHHHCCCCCCEEEEEECCCEEEE
PQAATFEIQDRVFVFKVVDGKTQSAPVEVTRVNGGQEYIVNAGLNSGDVIVAEGVGLLRE
CCCCEEEEECEEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCEEEECCCCCCCC
GTPIEVKQN
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]