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The map label for this gene is atpA [H]

Identifier: 150007476

GI number: 150007476

Start: 975041

End: 976798

Strand: Direct

Name: atpA [H]

Synonym: BDI_0827

Alternate gene names: 150007476

Gene position: 975041-976798 (Clockwise)

Preceding gene: 150007475

Following gene: 150007477

Centisome position: 20.27

GC content: 48.52

Gene sequence:

>1758_bases
ATGGCTACGAAAGGAATTGTAAAAGGAATCGTATCCAACCTAGTAACCGTAGAGGTGGATGGTCCGGTTTCTCAGAATGA
GATCTGTTACATTTCTGTCGGAGGCGTGAAGCTGATGTCGGAAGTAATCAAGGTGATAGGTAAGAATGCCTTTGTACAAG
TATTTGAGAGCACACGTGGTATGCGTGTCGGCGACGAGGCTGAATTCCAAGGGCATATGTTGGAAGTTACGCTGGGTCCG
GGTATGTTGTCCCGCAACTATGACGGTTTGCAGAATGACTTGGACAAGATGGAAGGTGTATTCTTGAAACGTGGCGATTA
TACGTTTGCGTTGGACAATGATAAGAAGTGGGATTTCAAGCCTCTGGCTAAAGCGGGCGATACCGTGAGCGCCGGTGATT
GGCTGGGAGAGGTGGACGAGAATTTCCAACCTCATAAGATTATGGTCCCCTTTAAGTTCGAGGGATCTTATACTGTGAAA
TCGGTGGTTCCAGCCGGACAATATACCATCAATGATACGATGGCTGTCCTTACGGACGAAAATGGCACGGACGTAAACGT
GACGATGATCCAGAAATGGCCAGTAAAGAAAGCTATCACTTGTTATAAGGAAAAGCCCCGTCCATTCAAATTGCTGGAGA
CGGGCGTTCGTACGATCGATACCGTGAACCCGATCGTTGAGGGTGGTACCGGATTTATCCCCGGTCCGTTCGGTACGGGC
AAGACGGTGCTTCAGCACGCTATCTCTAAACAAGCGGAAGCGGATATCGTGATTATCGCCGCCTGCGGTGAGCGTGCGAA
TGAGGTCGTAGAGGTATTTACGGAGTTCCCGGAATTGGTAGACCCGCATACGGGACGTAAATTGATGGAACGTACGATCA
TTATCGCCAATACATCCAACATGCCGGTAGCCGCTCGTGAGGCATCCGTATATACGGCGATGACCATCGCCGAGTATTAT
CGCAGCATGGGTTTGAAGGTTCTGTTGATGGCCGACTCTACTTCCCGCTGGGCACAGGCTTTGCGTGAGATGTCCAACCG
TTTGGAGGAGTTGCCGGGACCGGATGCTTTCCCGATGGACTTGTCCGCTATCGTGGCGAACTTCTACGCTCGTGCGGGAT
TCGTTCATTTGAATAACAACGCTACAGGCTCCGTCACTTTCATCGGTACGGTATCGCCGGCCGGTGGAAACTTGAAGGAG
CCAGTGACCGAGAATACGAAGAAGGTGGCCCGTTGTTTCTATGCCTTGGAGCAGGAGCGTGCCGACCGTAAACGTTATCC
GGCCGTAAACCCGATCGAGAGTTATTCCAAGTATATCGAGTATCCAGAGTTTCAGGAATACATCGCTAAACATATCTCCC
CGGAATGGATCGAGAAAGTAAACGAGATCAAGACCCGTATGTTGCGTGGTAAGGAGATCTCCGAGCAAATCAATATCTTG
GGTGATGATGGTGTGCCTGTCGAGTATCACGTTACATTCTGGAAGTCCGAGTTGATCGACTTCGTGATCTTGCAACAGGA
TGCTTTCGATGCCATCGATGCGGTTACTCCGTTGCGACGTCAGGAATTCATGCTGGATAGAGTCGTAAATGTTTGCCGTT
CAGAGTTTAAGTTTGATAACTTCCTTGAGGTTATGGACTACTTTAAGAAGATGATCAACATCTTTAAGCAGATGAACTAT
TCGGAATATGAGAGTGACCAATTCAAGAAGTTTAATACGGAACTGGATGAACTTTTGAAGGAGAGAATCGAAAATTAA

Upstream 100 bases:

>100_bases
GGCGAGAGGCGAGAAGACTTTCCGTGAATTGGTAGGCGCCATGAAGATGGGTAGTGAGAATGCGTTGGAAGAATTTAAAA
GAAACAATATAAAATAAATT

Downstream 100 bases:

>100_bases
AAGAGTTATGGCAACAAAAGCATTTCAAAAAATATATACGAAGATTACCCAGATCACAAAAGCTACCTGTTCGCTGAAAG
CAACGGGAGTTGGGTATGAT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIKVIGKNAFVQVFESTRGMRVGDEAEFQGHMLEVTLGP
GMLSRNYDGLQNDLDKMEGVFLKRGDYTFALDNDKKWDFKPLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVK
SVVPAGQYTINDTMAVLTDENGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRTIDTVNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEVFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTIAEYY
RSMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMDLSAIVANFYARAGFVHLNNNATGSVTFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQERADRKRYPAVNPIESYSKYIEYPEFQEYIAKHISPEWIEKVNEIKTRMLRGKEISEQINIL
GDDGVPVEYHVTFWKSELIDFVILQQDAFDAIDAVTPLRRQEFMLDRVVNVCRSEFKFDNFLEVMDYFKKMINIFKQMNY
SEYESDQFKKFNTELDELLKERIEN

Sequences:

>Translated_585_residues
MATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIKVIGKNAFVQVFESTRGMRVGDEAEFQGHMLEVTLGP
GMLSRNYDGLQNDLDKMEGVFLKRGDYTFALDNDKKWDFKPLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVK
SVVPAGQYTINDTMAVLTDENGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRTIDTVNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEVFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTIAEYY
RSMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMDLSAIVANFYARAGFVHLNNNATGSVTFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQERADRKRYPAVNPIESYSKYIEYPEFQEYIAKHISPEWIEKVNEIKTRMLRGKEISEQINIL
GDDGVPVEYHVTFWKSELIDFVILQQDAFDAIDAVTPLRRQEFMLDRVVNVCRSEFKFDNFLEVMDYFKKMINIFKQMNY
SEYESDQFKKFNTELDELLKERIEN
>Mature_584_residues
ATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIKVIGKNAFVQVFESTRGMRVGDEAEFQGHMLEVTLGPG
MLSRNYDGLQNDLDKMEGVFLKRGDYTFALDNDKKWDFKPLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVKS
VVPAGQYTINDTMAVLTDENGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRTIDTVNPIVEGGTGFIPGPFGTGK
TVLQHAISKQAEADIVIIAACGERANEVVEVFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTIAEYYR
SMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMDLSAIVANFYARAGFVHLNNNATGSVTFIGTVSPAGGNLKEP
VTENTKKVARCFYALEQERADRKRYPAVNPIESYSKYIEYPEFQEYIAKHISPEWIEKVNEIKTRMLRGKEISEQINILG
DDGVPVEYHVTFWKSELIDFVILQQDAFDAIDAVTPLRRQEFMLDRVVNVCRSEFKFDNFLEVMDYFKKMINIFKQMNYS
EYESDQFKKFNTELDELLKERIEN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=539, Percent_Identity=38.5899814471243, Blast_Score=356, Evalue=4e-98,
Organism=Homo sapiens, GI32189394, Length=354, Percent_Identity=24.0112994350282, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI19913428, Length=248, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790170, Length=324, Percent_Identity=25.3086419753086, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788251, Length=227, Percent_Identity=27.7533039647577, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=238, Percent_Identity=27.3109243697479, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=548, Percent_Identity=38.5036496350365, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI25144756, Length=237, Percent_Identity=26.5822784810127, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17510931, Length=244, Percent_Identity=25.4098360655738, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320016, Length=278, Percent_Identity=41.3669064748201, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6322581, Length=393, Percent_Identity=24.9363867684478, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319603, Length=353, Percent_Identity=23.2294617563739, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=236, Percent_Identity=24.1525423728814, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583992, Length=597, Percent_Identity=35.5108877721943, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24583988, Length=530, Percent_Identity=37.7358490566038, Blast_Score=348, Evalue=9e-96,
Organism=Drosophila melanogaster, GI24583986, Length=530, Percent_Identity=37.7358490566038, Blast_Score=348, Evalue=9e-96,
Organism=Drosophila melanogaster, GI24583984, Length=530, Percent_Identity=37.7358490566038, Blast_Score=348, Evalue=9e-96,
Organism=Drosophila melanogaster, GI20129479, Length=535, Percent_Identity=36.4485981308411, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI28574560, Length=241, Percent_Identity=29.045643153527, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24638766, Length=358, Percent_Identity=24.3016759776536, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281361666, Length=267, Percent_Identity=25.4681647940075, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646341, Length=267, Percent_Identity=25.4681647940075, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136796, Length=267, Percent_Identity=25.4681647940075, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65944; Mature: 65813

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIKVIGKNAFVQVFESTRG
CCCHHHHHHHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHCCC
MRVGDEAEFQGHMLEVTLGPGMLSRNYDGLQNDLDKMEGVFLKRGDYTFALDNDKKWDFK
CCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEEECCCCCCCCC
PLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVKSVVPAGQYTINDTMAVLTDE
HHHHCCCCCCCCCHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCEEECCEEEEEECC
NGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRTIDTVNPIVEGGTGFIPGPFGTG
CCCEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEVFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMTIAEYYRSMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMD
CCEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LSAIVANFYARAGFVHLNNNATGSVTFIGTVSPAGGNLKEPVTENTKKVARCFYALEQER
HHHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADRKRYPAVNPIESYSKYIEYPEFQEYIAKHISPEWIEKVNEIKTRMLRGKEISEQINIL
HHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCEE
GDDGVPVEYHVTFWKSELIDFVILQQDAFDAIDAVTPLRRQEFMLDRVVNVCRSEFKFDN
CCCCCCEEEEEEHHHHHHHHHHEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHH
FLEVMDYFKKMINIFKQMNYSEYESDQFKKFNTELDELLKERIEN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATKGIVKGIVSNLVTVEVDGPVSQNEICYISVGGVKLMSEVIKVIGKNAFVQVFESTRG
CCHHHHHHHHHCEEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHCCC
MRVGDEAEFQGHMLEVTLGPGMLSRNYDGLQNDLDKMEGVFLKRGDYTFALDNDKKWDFK
CCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCEEEEECCCCCCCCC
PLAKAGDTVSAGDWLGEVDENFQPHKIMVPFKFEGSYTVKSVVPAGQYTINDTMAVLTDE
HHHHCCCCCCCCCHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCEEECCEEEEEECC
NGTDVNVTMIQKWPVKKAITCYKEKPRPFKLLETGVRTIDTVNPIVEGGTGFIPGPFGTG
CCCEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEVFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMTIAEYYRSMGLKVLLMADSTSRWAQALREMSNRLEELPGPDAFPMD
CCEEEHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LSAIVANFYARAGFVHLNNNATGSVTFIGTVSPAGGNLKEPVTENTKKVARCFYALEQER
HHHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADRKRYPAVNPIESYSKYIEYPEFQEYIAKHISPEWIEKVNEIKTRMLRGKEISEQINIL
HHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHCEE
GDDGVPVEYHVTFWKSELIDFVILQQDAFDAIDAVTPLRRQEFMLDRVVNVCRSEFKFDN
CCCCCCEEEEEEHHHHHHHHHHEECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCHHH
FLEVMDYFKKMINIFKQMNYSEYESDQFKKFNTELDELLKERIEN
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA