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The map label for this gene is lpd [H]

Identifier: 150007340

GI number: 150007340

Start: 820298

End: 821653

Strand: Reverse

Name: lpd [H]

Synonym: BDI_0690

Alternate gene names: 150007340

Gene position: 821653-820298 (Counterclockwise)

Preceding gene: 150007341

Following gene: 150007339

Centisome position: 17.08

GC content: 46.46

Gene sequence:

>1356_bases
ATGTATATGGAATATGACATAGCAATCATAGGCGGTGGACCTGCGGGTTACACCGCCGCCGAAAGGGCTTCGGAGAATGG
ATTAAAAACGATCCTTTTCGAGAAGAACGCTATCGGTGGCGTCTGCCTAAACGAGGGATGTATCCCGACAAAAACTCTTT
TATACTCCGCCAAGATACTAGACAGTATCAAAAGTGCCTCCAAATATGGTATAGTGGCGATGAAAGACCCAAGTTTCGAC
TTGGCAAAGATTATCGACCGGAAGAACAAGACCGTCCGTAAACTTACGCTCGGGGTAAAAGCCCGGCTTACGGGTAACGG
CGTCACCATCGTAGAAGGAGAGGCACGAATCACCGGAGAGGAGTTTGGAAATATACGGATTCACTGCGATGGAAAAGAGT
ATTTAGTGAAGAATGTGTTAGTATGCACAGGCTCTGAAACCGTGATCCCTCCTATCAAAGGGTTATCAGAGGTCAAGTAT
TGGACTTCCCGGGAAGCCCTTGATCTCAACGATTTGCCAAAATCGTTAGCGATTATCGGTGGTGGCGTGATCGGAATGGA
GTTCGCCTCATTCTTTAACAGTATGGGCGTAAAGGTGAAGGTAATCGAGATGCTACCCGAGATATTAGGGAATATGGATA
AAGAAACCTCAGCGATGCTTCGATCCGAGTATAAGAAAAAAGGCGTAGAGTTTTTCTTGAATACCAAAGTTACAGAGGTA
TCGGCAGAGAAAGTCTTTGTTGAGAAAAATGGCAAGGCAGACACGATTGAAGCCGATAAAATATTGGTGAGCGTGGGCCG
CCGTCCGATTACAAAGAGTCTGGGACTCGAAAATCTAGCGATCGAAATACAAGGGGCCGGTGTAAAGGTAAACGAACATA
TGCTGACTTCCCATCCACATGTATATGCGGCTGGAGATATTACCGGTTTTTCCCTGCTGGCACATACGGCTTACCGGGAA
GCGGAAGTTGCCATACACCATATCCTAGGCATACCGGACGAGATGAGCTATAAAGCCATTCCGGCGGTAGTTTATACGAA
TCCGGAATTGGCGAGCGTGGGTAAGACAGAAGAGGAATTGATAGCGAATGGGGAAAGTTTTCGTGTTCAAAAGATCCCGA
TGACCTATTCCGGACGTTTCGTCGCAGAGAACGAGAATGGTAATGGTTTATGTAAACTGATCACGGACGACGAGGATCGT
ATCATCGGTTGCCATCTACTAGGGAATCCGGCATCCGAGATTATCGTCACCGCCGGAATCGCTGTCGAGAATGGTTATAC
AGTCGATGAATTTAAGAAAAATATTTTCCCGCATCCGACAGTCAGTGAGATCCTCCACGAAAGTTTATATATCTAA

Upstream 100 bases:

>100_bases
TGATCGCCGAGATGCCGTTCGGAACCTCTACCCAGGAACCGGGAGAAAAACAATTCGCCCCATTAGAGGAACGAATTTTA
GTATTCAAATAATTATAATA

Downstream 100 bases:

>100_bases
TAAAACGCCTAACTAAAACAGTTTCCTGATGCTTTGCATTCACAATACACAAACGGATCCATACTTCAATTTGGCCGCCG
AAGAGTATCTGCTCAAGAAT

Product: dihydrolipoamide dehydrogenase

Products: NA

Alternate protein names: Dihydrolipoamide dehydrogenase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MYMEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEGCIPTKTLLYSAKILDSIKSASKYGIVAMKDPSFD
LAKIIDRKNKTVRKLTLGVKARLTGNGVTIVEGEARITGEEFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKY
WTSREALDLNDLPKSLAIIGGGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAMLRSEYKKKGVEFFLNTKVTEV
SAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLENLAIEIQGAGVKVNEHMLTSHPHVYAAGDITGFSLLAHTAYRE
AEVAIHHILGIPDEMSYKAIPAVVYTNPELASVGKTEEELIANGESFRVQKIPMTYSGRFVAENENGNGLCKLITDDEDR
IIGCHLLGNPASEIIVTAGIAVENGYTVDEFKKNIFPHPTVSEILHESLYI

Sequences:

>Translated_451_residues
MYMEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEGCIPTKTLLYSAKILDSIKSASKYGIVAMKDPSFD
LAKIIDRKNKTVRKLTLGVKARLTGNGVTIVEGEARITGEEFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKY
WTSREALDLNDLPKSLAIIGGGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAMLRSEYKKKGVEFFLNTKVTEV
SAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLENLAIEIQGAGVKVNEHMLTSHPHVYAAGDITGFSLLAHTAYRE
AEVAIHHILGIPDEMSYKAIPAVVYTNPELASVGKTEEELIANGESFRVQKIPMTYSGRFVAENENGNGLCKLITDDEDR
IIGCHLLGNPASEIIVTAGIAVENGYTVDEFKKNIFPHPTVSEILHESLYI
>Mature_451_residues
MYMEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEGCIPTKTLLYSAKILDSIKSASKYGIVAMKDPSFD
LAKIIDRKNKTVRKLTLGVKARLTGNGVTIVEGEARITGEEFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKY
WTSREALDLNDLPKSLAIIGGGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAMLRSEYKKKGVEFFLNTKVTEV
SAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLENLAIEIQGAGVKVNEHMLTSHPHVYAAGDITGFSLLAHTAYRE
AEVAIHHILGIPDEMSYKAIPAVVYTNPELASVGKTEEELIANGESFRVQKIPMTYSGRFVAENENGNGLCKLITDDEDR
IIGCHLLGNPASEIIVTAGIAVENGYTVDEFKKNIFPHPTVSEILHESLYI

Specific function: Has chromate reductase activity [H]

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=461, Percent_Identity=35.5748373101952, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI50301238, Length=462, Percent_Identity=27.2727272727273, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI22035672, Length=430, Percent_Identity=25.5813953488372, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI291045266, Length=435, Percent_Identity=25.0574712643678, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI33519430, Length=442, Percent_Identity=23.3031674208145, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33519428, Length=442, Percent_Identity=23.3031674208145, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33519426, Length=442, Percent_Identity=23.3031674208145, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI148277065, Length=442, Percent_Identity=23.3031674208145, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI148277071, Length=442, Percent_Identity=23.3031674208145, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI291045268, Length=435, Percent_Identity=23.6781609195402, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786307, Length=462, Percent_Identity=34.1991341991342, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI87082354, Length=454, Percent_Identity=30.1762114537445, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI87081717, Length=460, Percent_Identity=29.3478260869565, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789915, Length=434, Percent_Identity=23.963133640553, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789765, Length=257, Percent_Identity=29.1828793774319, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789065, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565766, Length=458, Percent_Identity=37.3362445414847, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI71983419, Length=455, Percent_Identity=27.6923076923077, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71983429, Length=455, Percent_Identity=27.6923076923077, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17557007, Length=476, Percent_Identity=25.8403361344538, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71982272, Length=442, Percent_Identity=25.5656108597285, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321091, Length=467, Percent_Identity=35.9743040685225, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6325240, Length=471, Percent_Identity=29.5116772823779, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325166, Length=465, Percent_Identity=24.9462365591398, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI21358499, Length=459, Percent_Identity=37.9084967320261, Blast_Score=253, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24640553, Length=464, Percent_Identity=23.2758620689655, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640549, Length=464, Percent_Identity=23.2758620689655, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24640551, Length=467, Percent_Identity=23.5546038543897, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI17737741, Length=471, Percent_Identity=25.0530785562633, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR006258
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.4 [H]

Molecular weight: Translated: 49047; Mature: 49047

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEGCIPTKTLLYSAKIL
CEEEEEEEEECCCCCCCCHHHHHCCCCCEEEEEECCCCCCEEECCCCCCHHHHHHHHHHH
DSIKSASKYGIVAMKDPSFDLAKIIDRKNKTVRKLTLGVKARLTGNGVTIVEGEARITGE
HHHHCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEEEEEEECCCEEEEECCEEECCC
EFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKYWTSREALDLNDLPKSLAIIG
CCCCEEEEECCHHHHEEEEEEECCCCEECCCCCCHHHHHHHCCCCCCCHHHCCCHHHHHC
GGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAMLRSEYKKKGVEFFLNTKVTEV
CCHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECEEEEE
SAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLENLAIEIQGAGVKVNEHMLTSHPH
ECEEEEEECCCCCCEEEHHHHEEECCCCCCHHHCCCCEEEEEEECCCEEECCCEECCCCC
VYAAGDITGFSLLAHTAYREAEVAIHHILGIPDEMSYKAIPAVVYTNPELASVGKTEEEL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHCCCCHHHH
IANGESFRVQKIPMTYSGRFVAENENGNGLCKLITDDEDRIIGCHLLGNPASEIIVTAGI
HCCCCCEEEEECCEEECCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEEEE
AVENGYTVDEFKKNIFPHPTVSEILHESLYI
EECCCCCHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYMEYDIAIIGGGPAGYTAAERASENGLKTILFEKNAIGGVCLNEGCIPTKTLLYSAKIL
CEEEEEEEEECCCCCCCCHHHHHCCCCCEEEEEECCCCCCEEECCCCCCHHHHHHHHHHH
DSIKSASKYGIVAMKDPSFDLAKIIDRKNKTVRKLTLGVKARLTGNGVTIVEGEARITGE
HHHHCCCCCCEEEEECCCCHHHHHHHCCCCEEEEEEEEEEEEEECCCEEEEECCEEECCC
EFGNIRIHCDGKEYLVKNVLVCTGSETVIPPIKGLSEVKYWTSREALDLNDLPKSLAIIG
CCCCEEEEECCHHHHEEEEEEECCCCEECCCCCCHHHHHHHCCCCCCCHHHCCCHHHHHC
GGVIGMEFASFFNSMGVKVKVIEMLPEILGNMDKETSAMLRSEYKKKGVEFFLNTKVTEV
CCHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECEEEEE
SAEKVFVEKNGKADTIEADKILVSVGRRPITKSLGLENLAIEIQGAGVKVNEHMLTSHPH
ECEEEEEECCCCCCEEEHHHHEEECCCCCCHHHCCCCEEEEEEECCCEEECCCEECCCCC
VYAAGDITGFSLLAHTAYREAEVAIHHILGIPDEMSYKAIPAVVYTNPELASVGKTEEEL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHCCCCHHHH
IANGESFRVQKIPMTYSGRFVAENENGNGLCKLITDDEDRIIGCHLLGNPASEIIVTAGI
HCCCCCEEEEECCEEECCEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEEEE
AVENGYTVDEFKKNIFPHPTVSEILHESLYI
EECCCCCHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA