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The map label for this gene is cdr [H]

Identifier: 150007196

GI number: 150007196

Start: 641712

End: 644180

Strand: Reverse

Name: cdr [H]

Synonym: BDI_0541

Alternate gene names: 150007196

Gene position: 644180-641712 (Counterclockwise)

Preceding gene: 150007197

Following gene: 150007189

Centisome position: 13.39

GC content: 49.53

Gene sequence:

>2469_bases
ATGAAGTATTTGATTATTGGAGGTGTAGCCGGTGGAGCTACCGTAGCAGCCCGGCTGCGTAGAATGGACGAGAAAGCGGA
AATCATCCTTTTCGAACGTGGAAAATATGTTTCTTACGCAAACTGTGGATTACCTTATTATATAGGAGACACGATCAACG
ACCGGAATAAATTATTCGTACAAACCGTGAAAGGCTTCACGGATCGATTCCGCATCGATATACGTACGGAGCAGGAAGTG
ACCCGAATCCTTCCCGAATCCAAGCAAGTGGAGGTAAAGAAACTCGGCACAGGAGAAACCTACACGGAGACTTACGATAA
ACTAGTGCTCTCTCCCGGTGCGGAGCCTTTGCGTCCACGCATCGAAGGAATCGAGAGTAAAAAGATATTCACGTTACGTA
ACGTGCCGGATACGGACACGATCAAGAATTACGTGAACACAGAAAAGCCCCGTACCGCCGTTGTTGTAGGGGGTGGTTTC
ATCGGCTTGGAGATGGCGGAGAATTTGCATGAGCTGGGTATCCACGTCACTGTCGTGGAAATGGCTAACCAAGTGATGGC
ACCCCTCGACTATTCCATGGCCGCTATCGTACATCAGCAATTGATCGGCAAGCAGGTAGGCTTGATGCTGGAAGATGGCG
TATCTCGTTTCGAGGAGACTTCCGGAGGCGTGACCGTTCATTTGAAAAGTGGGAAGCAGATCCCGGCGGATATGGTTTTA
TTGAGTATCGGTGTCCGTCCGGAAACCCGATTGGCCAAAGAAGCGGGACTTACGATCGGAGCACTCGGCGGTATCGCTGT
CAATGAATATATGCAGACCTCGAACCCGGATATTTATGCGTTGGGAGATGCCGTGGAAGTACGCCACCTCGTGACAGGCA
AACCAGCCTTGATCCCATTGGCGGGTCCGGCGAATAAGCAAGGACGTATCGTAGCCGATAATATCGTATCCGGCAATAAG
GAAACTTATGACGGGACGATGGGAACCTCTATCGCCAAGGTATTCGACTTGACGGTCGCCACGGCGGGAGCTAACGCTAA
GCTGTTGAAACGGGAAGGAATCGCTTATCAATCCTCCTATACGCATGGAGCCTCGCATGCGGGATATTACCCGGGAGCCG
TGCCTTTATCGATCAAGATATTGTTCGCACCGGAAGACGGACGACTGTTAGGGGCGCAAGTCGTAGGTTTCGGAGGCGTA
GACAAACGGATCGAGATGTTAGCGCAAGTGATCCAGCGGAAAGGTACGGTCTATGACCTGACTGAGTTAGAACATGCGTA
TGCTCCTCCTTATTCAGCCGCTAAAGATCCTGTAAATATGGCCGGTTTCGTAGCGGAGAACCTGCTTACGGGAAAAGCGA
AAGCGATCCAGTGGAGAGAAATCCAGAACTTATCGCCAGATACCGTACGTATCGATGTCCGTACCCGTGACGAGTACAGC
TTAGGGACAATCCCCGGCTTCATCAATATCCCGGTTGATGAGTTAAGAGAACATTTGGCGGAACTGCCCAAGGATAAACC
GATCGTAGTGACTTGCGCCGTTGGATTAAGGGGCTATTTGGCTTATCGCATCCTGACTCAAAATGGCTTCACGAATGTCC
GGAACCTATCCGGTGGTTACAAGACTTGGAGTGTAGCGACAGCAAAGATCAAGAATGAGCCGGCCTGCGCACCTTGTTCG
TCCGAAGCTGTTTCTGATAAGGCATCTGGTAAAAGTAGCTCTTGCAAATCGACTCCGGCAGCTACGGCGATTAAGGTAGA
CGCTTGCGGATTAATGTGTCCGGGACCGATCATGCAGTTGAAAAAGAACTATGAGAACTTGCGGGAAAATGAGTCATTGG
AAATCACCGCAACAGATCAGGCTTTCGGAAAAGATGTCTCTTCATGGTGCAAGATAACCGGGGCAGAGTTAGTCTCTCTG
GAAAATAAGGGAGGCACGATCGCCGCCACGGTACGAAAAAAAAAAGCTGAATGCAAAATAGCGACAGGTGGTAATAGTGC
CGACAACAAGACATTGATCGTTTTCAGCGATGACCTCGATAAGGCGTTGGCCTCATTCGTCATAGCGAACGGGGCTGCCT
CCACCGGAAAGAAGGTGACTATGTTCTTTACTTTCTGGGGACTTAACGTGATTAAGAAACGGGAAAAACCTGCCGTATCT
AAAGATATCTTCGGCAAGATGTTTGGCTGGATGCTTCCGGCAAATAGCGAAAAGCTGAAACTATCTAAAATGAATATGGG
TGGAGCCGGCAGTTGGATGATGCGCCTTATCATGAAGAAGAAACGGATCGACAGCTTGGAAAGCCTTATGGCACAAGCCG
TAGAGAATGGTATCGAGATGATCGCCTGCACGATGAGCATGGACGTAATGGGCGTCAAAAAAGAAGAACTGATGGATAAC
GTTGTCCTAGGAGGCGTAGCCACCTATCTGGAACGTGCGGAAGACGCAAACGTAAACTTATTCATCTAA

Upstream 100 bases:

>100_bases
AATCAACTCAAAGAATACATACAAAAGGGATGAATCCCTTTTTTTAACTAATTATTGTCTACTAACAAATATGTATAATA
CAAATTAAATAAAAATAGAT

Downstream 100 bases:

>100_bases
TTCATTCAAAAAAAATATCCCAGCATATCCACAATAAGGACAATGCTGGGATATTTTATAAAAAAGAGATTATACGAAGT
CCAATGTTGAACGTTTCATA

Product: pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 822; Mature: 822

Protein sequence:

>822_residues
MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGLPYYIGDTINDRNKLFVQTVKGFTDRFRIDIRTEQEV
TRILPESKQVEVKKLGTGETYTETYDKLVLSPGAEPLRPRIEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGF
IGLEMAENLHELGIHVTVVEMANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFEETSGGVTVHLKSGKQIPADMVL
LSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNPDIYALGDAVEVRHLVTGKPALIPLAGPANKQGRIVADNIVSGNK
ETYDGTMGTSIAKVFDLTVATAGANAKLLKREGIAYQSSYTHGASHAGYYPGAVPLSIKILFAPEDGRLLGAQVVGFGGV
DKRIEMLAQVIQRKGTVYDLTELEHAYAPPYSAAKDPVNMAGFVAENLLTGKAKAIQWREIQNLSPDTVRIDVRTRDEYS
LGTIPGFINIPVDELREHLAELPKDKPIVVTCAVGLRGYLAYRILTQNGFTNVRNLSGGYKTWSVATAKIKNEPACAPCS
SEAVSDKASGKSSSCKSTPAATAIKVDACGLMCPGPIMQLKKNYENLRENESLEITATDQAFGKDVSSWCKITGAELVSL
ENKGGTIAATVRKKKAECKIATGGNSADNKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVS
KDIFGKMFGWMLPANSEKLKLSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEMIACTMSMDVMGVKKEELMDN
VVLGGVATYLERAEDANVNLFI

Sequences:

>Translated_822_residues
MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGLPYYIGDTINDRNKLFVQTVKGFTDRFRIDIRTEQEV
TRILPESKQVEVKKLGTGETYTETYDKLVLSPGAEPLRPRIEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGF
IGLEMAENLHELGIHVTVVEMANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFEETSGGVTVHLKSGKQIPADMVL
LSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNPDIYALGDAVEVRHLVTGKPALIPLAGPANKQGRIVADNIVSGNK
ETYDGTMGTSIAKVFDLTVATAGANAKLLKREGIAYQSSYTHGASHAGYYPGAVPLSIKILFAPEDGRLLGAQVVGFGGV
DKRIEMLAQVIQRKGTVYDLTELEHAYAPPYSAAKDPVNMAGFVAENLLTGKAKAIQWREIQNLSPDTVRIDVRTRDEYS
LGTIPGFINIPVDELREHLAELPKDKPIVVTCAVGLRGYLAYRILTQNGFTNVRNLSGGYKTWSVATAKIKNEPACAPCS
SEAVSDKASGKSSSCKSTPAATAIKVDACGLMCPGPIMQLKKNYENLRENESLEITATDQAFGKDVSSWCKITGAELVSL
ENKGGTIAATVRKKKAECKIATGGNSADNKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVS
KDIFGKMFGWMLPANSEKLKLSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEMIACTMSMDVMGVKKEELMDN
VVLGGVATYLERAEDANVNLFI
>Mature_822_residues
MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGLPYYIGDTINDRNKLFVQTVKGFTDRFRIDIRTEQEV
TRILPESKQVEVKKLGTGETYTETYDKLVLSPGAEPLRPRIEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGF
IGLEMAENLHELGIHVTVVEMANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFEETSGGVTVHLKSGKQIPADMVL
LSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNPDIYALGDAVEVRHLVTGKPALIPLAGPANKQGRIVADNIVSGNK
ETYDGTMGTSIAKVFDLTVATAGANAKLLKREGIAYQSSYTHGASHAGYYPGAVPLSIKILFAPEDGRLLGAQVVGFGGV
DKRIEMLAQVIQRKGTVYDLTELEHAYAPPYSAAKDPVNMAGFVAENLLTGKAKAIQWREIQNLSPDTVRIDVRTRDEYS
LGTIPGFINIPVDELREHLAELPKDKPIVVTCAVGLRGYLAYRILTQNGFTNVRNLSGGYKTWSVATAKIKNEPACAPCS
SEAVSDKASGKSSSCKSTPAATAIKVDACGLMCPGPIMQLKKNYENLRENESLEITATDQAFGKDVSSWCKITGAELVSL
ENKGGTIAATVRKKKAECKIATGGNSADNKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVS
KDIFGKMFGWMLPANSEKLKLSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEMIACTMSMDVMGVKKEELMDN
VVLGGVATYLERAEDANVNLFI

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI65787454, Length=324, Percent_Identity=28.3950617283951, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI21389617, Length=324, Percent_Identity=28.3950617283951, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI226437568, Length=324, Percent_Identity=28.3950617283951, Blast_Score=111, Evalue=4e-24,
Organism=Homo sapiens, GI91199540, Length=302, Percent_Identity=27.4834437086093, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1789065, Length=319, Percent_Identity=28.8401253918495, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI1786307, Length=303, Percent_Identity=29.3729372937294, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789765, Length=403, Percent_Identity=25.5583126550869, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082354, Length=317, Percent_Identity=27.7602523659306, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788892, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559934, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325166, Length=318, Percent_Identity=23.5849056603774, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585130, Length=322, Percent_Identity=24.223602484472, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281359715, Length=328, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281359713, Length=328, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639250, Length=328, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18543267, Length=328, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639252, Length=328, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639257, Length=328, Percent_Identity=24.390243902439, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358499, Length=364, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 89058; Mature: 89058

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50206 RHODANESE_3 ; PS01148 UPF0033

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGLPYYIGDTINDRNKLFV
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCEEECCCCCCCCCEEH
QTVKGFTDRFRIDIRTEQEVTRILPESKQVEVKKLGTGETYTETYDKLVLSPGAEPLRPR
HHHHCCCEEEEEEEECHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEECCCCCCCCHH
IEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGFIGLEMAENLHELGIHVTVVE
HCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHCCCEEEEHH
MANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFEETSGGVTVHLKSGKQIPADMVL
HHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
LSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNPDIYALGDAVEVRHLVTGKPALIPL
EEECCCCCHHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEECCHHEEHHHHCCCCEEEEE
AGPANKQGRIVADNIVSGNKETYDGTMGTSIAKVFDLTVATAGANAKLLKREGIAYQSSY
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCEEHHHCCCEEECCC
THGASHAGYYPGAVPLSIKILFAPEDGRLLGAQVVGFGGVDKRIEMLAQVIQRKGTVYDL
CCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEH
TELEHAYAPPYSAAKDPVNMAGFVAENLLTGKAKAIQWREIQNLSPDTVRIDVRTRDEYS
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHEEEHHHHCCCCCCEEEEEEEECCCCC
LGTIPGFINIPVDELREHLAELPKDKPIVVTCAVGLRGYLAYRILTQNGFTNVRNLSGGY
CCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHEEEEEEEECCCCCCHHCCCCCC
KTWSVATAKIKNEPACAPCSSEAVSDKASGKSSSCKSTPAATAIKVDACGLMCPGPIMQL
EEEEEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
KKNYENLRENESLEITATDQAFGKDVSSWCKITGAELVSLENKGGTIAATVRKKKAECKI
HHHHHHHCCCCCEEEEECCHHHHCCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCEEE
ATGGNSADNKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVS
EECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHCCCCCHH
KDIFGKMFGWMLPANSEKLKLSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEM
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IACTMSMDVMGVKKEELMDNVVLGGVATYLERAEDANVNLFI
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MKYLIIGGVAGGATVAARLRRMDEKAEIILFERGKYVSYANCGLPYYIGDTINDRNKLFV
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCCCEEECCCCCCCCCEEH
QTVKGFTDRFRIDIRTEQEVTRILPESKQVEVKKLGTGETYTETYDKLVLSPGAEPLRPR
HHHHCCCEEEEEEEECHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEECCCCCCCCHH
IEGIESKKIFTLRNVPDTDTIKNYVNTEKPRTAVVVGGGFIGLEMAENLHELGIHVTVVE
HCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHCCCEEEEHH
MANQVMAPLDYSMAAIVHQQLIGKQVGLMLEDGVSRFEETSGGVTVHLKSGKQIPADMVL
HHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEE
LSIGVRPETRLAKEAGLTIGALGGIAVNEYMQTSNPDIYALGDAVEVRHLVTGKPALIPL
EEECCCCCHHHHHHCCCEEEECCCHHHHHHHHCCCCCEEEECCHHEEHHHHCCCCEEEEE
AGPANKQGRIVADNIVSGNKETYDGTMGTSIAKVFDLTVATAGANAKLLKREGIAYQSSY
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCEEHHHCCCEEECCC
THGASHAGYYPGAVPLSIKILFAPEDGRLLGAQVVGFGGVDKRIEMLAQVIQRKGTVYDL
CCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEH
TELEHAYAPPYSAAKDPVNMAGFVAENLLTGKAKAIQWREIQNLSPDTVRIDVRTRDEYS
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHEEEHHHHCCCCCCEEEEEEEECCCCC
LGTIPGFINIPVDELREHLAELPKDKPIVVTCAVGLRGYLAYRILTQNGFTNVRNLSGGY
CCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHEEEEEEEECCCCCCHHCCCCCC
KTWSVATAKIKNEPACAPCSSEAVSDKASGKSSSCKSTPAATAIKVDACGLMCPGPIMQL
EEEEEEEEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHH
KKNYENLRENESLEITATDQAFGKDVSSWCKITGAELVSLENKGGTIAATVRKKKAECKI
HHHHHHHCCCCCEEEEECCHHHHCCHHHHHHCCCCEEEEEECCCCEEEEEEECCCCCEEE
ATGGNSADNKTLIVFSDDLDKALASFVIANGAASTGKKVTMFFTFWGLNVIKKREKPAVS
EECCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHHCCCCCHH
KDIFGKMFGWMLPANSEKLKLSKMNMGGAGSWMMRLIMKKKRIDSLESLMAQAVENGIEM
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IACTMSMDVMGVKKEELMDNVVLGGVATYLERAEDANVNLFI
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA