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The map label for this gene is kdsB

Identifier: 150007177

GI number: 150007177

Start: 617438

End: 618193

Strand: Reverse

Name: kdsB

Synonym: BDI_0522

Alternate gene names: 150007177

Gene position: 618193-617438 (Counterclockwise)

Preceding gene: 150007178

Following gene: 150007173

Centisome position: 12.85

GC content: 46.3

Gene sequence:

>756_bases
ATGATGAAGTTTATAGGAATTATTCCGGCGAGATACGCCTCTACCCGTTTTCCGGGGAAGCCATTAGCGGATATGAACGG
AAAGCCCATGATACAACGTGTATATGAGCAAGTAAAGGATGTCTTAGACTCCGTTTGCGTAGCTACCGACGATATCCGGA
TAGAGAATGCGGTTAAAGCCTTCGGCGGCCAAGTCGTCATGACCTCCGATCAACATCGTAGCGGTACGGATCGTTGCTAC
GAGGCTTATCAGAAAATAGGCGAAGGGTATGATGTGATTGTCAATATCCAAGGTGACGAGCCTTTTATCCATCCCGAGCA
AATCCAGACGATCAAAACCTGCTTCGCCGACGCAAACACGCAAATAGCGACATTGGTAAAGCCTTTCCGTTCGGACGATG
ATTTCGAGAGTTCCCTATTCAATCCCAATTCCCCGAAAGTCGTACTCAACAAAAACAACGAGGCTATGTATTTCAGTCGA
TCTATTATTCCTTATATCCGGGGCAAGAAATATACGGAATGGTTGCCGAGTCATACCTTTTACAAACATATCGGGTTATA
TGCCTATCGTGCGCAAGTGCTGAAAGAAATCACCCAATTACCTCAATCCGCTTTAGAACTGGCGGAAAGCCTTGAGCAAT
TACGCTGGTTGGAAAACGGATATAAAATCAAGGTCGGCATCACAGAGCAAGAAACGATCGGTATAGATACACCGGAGGAC
ATGGAGAAAGCCTTAGCCTTCCTTGCGAACCGCTGA

Upstream 100 bases:

>100_bases
TTTTCGAGGAAGGAGATATCGTATGGATCGTAGGCGAACGGGATAAGTTGATCCAGTTAAGCGAAGGAAAAGTAGTAACC
AGTTAACAAAATGATATAGA

Downstream 100 bases:

>100_bases
TCACTTACACTATTATTCAATGAATATAGTCAGAGTAGTACCAATAGGTGGAGGAATAACGTTCTCGTAATTCCTCCTTT
GCTTTTCTACCCGATTTACA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKAFGGQVVMTSDQHRSGTDRCY
EAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANTQIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSR
SIIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
MEKALAFLANR

Sequences:

>Translated_251_residues
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKAFGGQVVMTSDQHRSGTDRCY
EAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANTQIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSR
SIIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
MEKALAFLANR
>Mature_251_residues
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKAFGGQVVMTSDQHRSGTDRCY
EAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANTQIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSR
SIIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
MEKALAFLANR

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=250, Percent_Identity=43.6, Blast_Score=188, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_PARD8 (A6L9D4)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301920.1
- ProteinModelPortal:   A6L9D4
- SMR:   A6L9D4
- STRING:   A6L9D4
- GeneID:   5305677
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0522
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- ProtClustDB:   PRK13368
- BioCyc:   PDIS435591:BDI_0522-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28572; Mature: 28572

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKA
CCCHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FGGQVVMTSDQHRSGTDRCYEAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANT
HCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSRSIIPYIRGKKYTEWLPSHTF
HHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCEEEEECCHHHHHCCCCHHHHCCCHHH
YKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCHHH
MEKALAFLANR
HHHHHHHHHCC
>Mature Secondary Structure
MMKFIGIIPARYASTRFPGKPLADMNGKPMIQRVYEQVKDVLDSVCVATDDIRIENAVKA
CCCHHCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FGGQVVMTSDQHRSGTDRCYEAYQKIGEGYDVIVNIQGDEPFIHPEQIQTIKTCFADANT
HCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCC
QIATLVKPFRSDDDFESSLFNPNSPKVVLNKNNEAMYFSRSIIPYIRGKKYTEWLPSHTF
HHHHHHHHHCCCCCHHHHCCCCCCCEEEEECCCCEEEEECCHHHHHCCCCHHHHCCCHHH
YKHIGLYAYRAQVLKEITQLPQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPED
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCHHH
MEKALAFLANR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA