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The map label for this gene is dapL

Identifier: 150006985

GI number: 150006985

Start: 360479

End: 361708

Strand: Reverse

Name: dapL

Synonym: BDI_0321

Alternate gene names: 150006985

Gene position: 361708-360479 (Counterclockwise)

Preceding gene: 150006986

Following gene: 150006984

Centisome position: 7.52

GC content: 50.81

Gene sequence:

>1230_bases
ATGGCACTAATTAATGAACATTTCCTGAAACTACAGAACAATTACCTTTTCTCCGACATCGCGAAAAAGGTAAACAGCTT
CAAGGTTACCCATCCCAAGGATAAGATCATTCGAATGGGTATTGGTGATGTTACGCAACCACTTGCCCCCGCCGTTATTG
AGGCGATGCATAAAGCCGTGGAAGAAATGGCGAGCAAGGATACATTCCACGGATATGGCCCCGAGCAGGGATATCCTTTC
CTAATCGACGCTATCATCAAGAACGATTATGCCAGCCGGGGAGTCTTTATCGAACCGAGCGAGGTATTCATCAGCGACGG
GGCGAAAAGCGATTGTGGAAATATAGGTGACATGCTCCGCCACGACAATAGTATCGGGGTGACAGACCCCGTATATCCGG
TCTACATCGACTCGAACGTAATGAGCGGACGCACCGGGGTATTGGAAAACGGGAAATGGAGCGATGTCGTATACATCCCT
TGCACGGCGGAAAACAACTTCGTACCGGATCTGCCCAGTCGCAGGGTGGACATCCTTTACCTCTGCTATCCCAATAACCC
GACCGGAACGACCTTGACTAAGGACGAATTGAAGAAATGGGTAAACTATGCCCTTGCCAACGACGTGCTTATCATGTACG
ACTCCGCTTACGAAGCTTATATACAGGACCCGAATATCCCCCACTCTATCTACGAGATCAAAGGAGCGAAGAAGGTAGCT
ATCGAATTCCGGAGCTTCTCTAAAACCGCCGGGTTCACGGGGATACGTTGCGGATACACGGTCGTACCGAAGGAGCTGAA
CGCCTTCACGCTGGACGGGCAACGGGTACAGTTGAACAAATTATGGAACCGTCGCCAATGCACGAAATTCAACGGAACCA
GTTACATAACCCAACGGGGTGCGGAAGCGGTTTATTCCACCGCCGGGAAACAGCAAGTGACAGCTACTATCAATTATTAT
ATGACCAACGCGAAGATCATGAAAGAGGGCCTGCAAAACTGCGGTCTCACGGTGTACGGAGGCGATAACGCCCCATACCT
CTGGCTAAAGACCCCGGACGGCCTCTCCTCATGGAAATTCTTTGACAAACTGCTTTATGAAGTCAAGATAGTCGGAACCC
CCGGAGTGGGATTCGGACCGAGCGGGGAAGGTTATCTACGCCTCACCGCTTTCGGCGATAGGGATGACACCCTAGAGGCC
ATGGCTAGGCTGAGGAAGTGGCTAAGATAA

Upstream 100 bases:

>100_bases
CCGGCGGAGCGGTCAACGTGTTCGAGGGATTCATCAAAGTCTGACATGGGGAACAAGACAAAACAACAAAAACAACAACA
TAAAAACAAAAGAACTGAGT

Downstream 100 bases:

>100_bases
GTCATTTACTATAAACAACAATAATCATCAGGTATTATGTCAAAGTTAAGATTTAGAGTCGTAGAATCGGCGTTCGAGAA
AAAAGCGACCGAGCTAACCA

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDVTQPLAPAVIEAMHKAVEEMASKDTFHGYGPEQGYPF
LIDAIIKNDYASRGVFIEPSEVFISDGAKSDCGNIGDMLRHDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIP
CTAENNFVPDLPSRRVDILYLCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYEAYIQDPNIPHSIYEIKGAKKVA
IEFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRVQLNKLWNRRQCTKFNGTSYITQRGAEAVYSTAGKQQVTATINYY
MTNAKIMKEGLQNCGLTVYGGDNAPYLWLKTPDGLSSWKFFDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFGDRDDTLEA
MARLRKWLR

Sequences:

>Translated_409_residues
MALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDVTQPLAPAVIEAMHKAVEEMASKDTFHGYGPEQGYPF
LIDAIIKNDYASRGVFIEPSEVFISDGAKSDCGNIGDMLRHDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIP
CTAENNFVPDLPSRRVDILYLCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYEAYIQDPNIPHSIYEIKGAKKVA
IEFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRVQLNKLWNRRQCTKFNGTSYITQRGAEAVYSTAGKQQVTATINYY
MTNAKIMKEGLQNCGLTVYGGDNAPYLWLKTPDGLSSWKFFDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFGDRDDTLEA
MARLRKWLR
>Mature_408_residues
ALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDVTQPLAPAVIEAMHKAVEEMASKDTFHGYGPEQGYPFL
IDAIIKNDYASRGVFIEPSEVFISDGAKSDCGNIGDMLRHDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIPC
TAENNFVPDLPSRRVDILYLCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYEAYIQDPNIPHSIYEIKGAKKVAI
EFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRVQLNKLWNRRQCTKFNGTSYITQRGAEAVYSTAGKQQVTATINYYM
TNAKIMKEGLQNCGLTVYGGDNAPYLWLKTPDGLSSWKFFDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFGDRDDTLEAM
ARLRKWLR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=25.2577319587629, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=386, Percent_Identity=21.7616580310881, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPAT_PARD8 (A6L8U2)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301728.1
- ProteinModelPortal:   A6L8U2
- SMR:   A6L8U2
- STRING:   A6L8U2
- GeneID:   5305476
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0321
- eggNOG:   COG0436
- HOGENOM:   HBG645860
- OMA:   VDLIYLC
- ProtClustDB:   PRK07590
- BioCyc:   PDIS435591:BDI_0321-MONOMER
- HAMAP:   MF_01642
- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03542

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.83

Molecular weight: Translated: 45779; Mature: 45647

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00105 AA_TRANSFER_CLASS_1; PS00133 CARBOXYPEPT_ZN_2

Important sites: BINDING 42-42 BINDING 72-72 BINDING 75-75 BINDING 109-109 BINDING 132-132 BINDING 186-186 BINDING 186-186 BINDING 214-214 BINDING 217-217 BINDING 245-245 BINDING 247-247 BINDING 256-256 BINDING 291-291 BINDING 387-387

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDVTQPLAPAVIEAMHKAV
CCCCHHHHHHHHCCCHHHHHHHHHHCEEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHH
EEMASKDTFHGYGPEQGYPFLIDAIIKNDYASRGVFIEPSEVFISDGAKSDCGNIGDMLR
HHHHCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCEEECCCCEEEECCCCCCCCHHHHHHH
HDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIPCTAENNFVPDLPSRRVDILY
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEE
LCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYEAYIQDPNIPHSIYEIKGAKKVA
EEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCHHEEECCCEEEE
IEFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRVQLNKLWNRRQCTKFNGTSYITQRG
EEEHHCCCCCCCCEEECCEEECCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCHHHHHHC
AEAVYSTAGKQQVTATINYYMTNAKIMKEGLQNCGLTVYGGDNAPYLWLKTPDGLSSWKF
HHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHH
FDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFGDRDDTLEAMARLRKWLR
HHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALINEHFLKLQNNYLFSDIAKKVNSFKVTHPKDKIIRMGIGDVTQPLAPAVIEAMHKAV
CCCHHHHHHHHCCCHHHHHHHHHHCEEEECCHHHEEEECCCCHHHHHHHHHHHHHHHHH
EEMASKDTFHGYGPEQGYPFLIDAIIKNDYASRGVFIEPSEVFISDGAKSDCGNIGDMLR
HHHHCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCEEECCCCEEEECCCCCCCCHHHHHHH
HDNSIGVTDPVYPVYIDSNVMSGRTGVLENGKWSDVVYIPCTAENNFVPDLPSRRVDILY
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEE
LCYPNNPTGTTLTKDELKKWVNYALANDVLIMYDSAYEAYIQDPNIPHSIYEIKGAKKVA
EEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCCHHEEECCCEEEE
IEFRSFSKTAGFTGIRCGYTVVPKELNAFTLDGQRVQLNKLWNRRQCTKFNGTSYITQRG
EEEHHCCCCCCCCEEECCEEECCCCCCEEEECCCEEEHHHHCCCCCCCCCCCCHHHHHHC
AEAVYSTAGKQQVTATINYYMTNAKIMKEGLQNCGLTVYGGDNAPYLWLKTPDGLSSWKF
HHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHCCEEEEECCCCCEEEEECCCCCHHHHH
FDKLLYEVKIVGTPGVGFGPSGEGYLRLTAFGDRDDTLEAMARLRKWLR
HHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA