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The map label for this gene is ribH

Identifier: 150006866

GI number: 150006866

Start: 207072

End: 207554

Strand: Reverse

Name: ribH

Synonym: BDI_0200

Alternate gene names: 150006866

Gene position: 207554-207072 (Counterclockwise)

Preceding gene: 150006867

Following gene: 150006865

Centisome position: 4.31

GC content: 44.93

Gene sequence:

>483_bases
ATGGCTACAGCTTATCAGAATTTATCCGAGTACGACTTCAACAGCGTACCTGATGCTTCAGAGATGAACATCGGCATCGT
AGTTGCTGAATGGAACAAGAACATTACCGAGAAGTTATTGGAAGGTGCTTGCAACACGCTTGAAAAGCACGGGGTGAAAC
CGGAGAACATCGTAGTTAAACGAGTTCCGGGTAGTTTTGAACTGACTTTTGGAGCCAAAAGATTGGCCGAGACTAAAGAA
TTAGACGCTGTGATCGTTCTGGGATGCGTCGTAAGAGGCGATACGCCACATTTTGATTACGTTTGTTCCGGCGTTACGCA
AGGCATTACAGAATTGAATTTAATGTACGATATTCCTTTCATTTTCGGCCTGTTAACTACCGACACCATGCAGCAATCCG
AGGATCGTGCGGGAGGTAGATATGGCAATAAAGGGGACGAGGCAGCGGTTACCGCAATAAAAATGGTAAATTTTTCTGCC
TAA

Upstream 100 bases:

>100_bases
ACCCGTGCTTCGGCAGGAAAATAAATAAACAGTATATTATATAGTATAACAGAGGATGTCTCGGTCAAACAAGGCATCCT
CTTCTTTTAAAGAGACAAGT

Downstream 100 bases:

>100_bases
ACGCTTGCAGGTTTCAAAATAAATCGTACCTTTGCACTGCAATTAAGAACAAGGGGGCAGTTACCAGAGTGGCCAAATGG
GGCTGACTGTAACTCAGCTG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGACNTLEKHGVKPENIVVKRVPGSFELTFGAKRLAETKE
LDAVIVLGCVVRGDTPHFDYVCSGVTQGITELNLMYDIPFIFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA

Sequences:

>Translated_160_residues
MATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGACNTLEKHGVKPENIVVKRVPGSFELTFGAKRLAETKE
LDAVIVLGCVVRGDTPHFDYVCSGVTQGITELNLMYDIPFIFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA
>Mature_159_residues
ATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGACNTLEKHGVKPENIVVKRVPGSFELTFGAKRLAETKEL
DAVIVLGCVVRGDTPHFDYVCSGVTQGITELNLMYDIPFIFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=144, Percent_Identity=46.5277777777778, Blast_Score=130, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324429, Length=151, Percent_Identity=36.4238410596026, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_PARD8 (A6L8H3)

Other databases:

- EMBL:   CP000140
- RefSeq:   YP_001301609.1
- ProteinModelPortal:   A6L8H3
- SMR:   A6L8H3
- STRING:   A6L8H3
- GeneID:   5305291
- GenomeReviews:   CP000140_GR
- KEGG:   pdi:BDI_0200
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- BioCyc:   PDIS435591:BDI_0200-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 17487; Mature: 17356

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGACNTLEKHGVKPENIVVK
CCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
RVPGSFELTFGAKRLAETKELDAVIVLGCVVRGDTPHFDYVCSGVTQGITELNLMYDIPF
ECCCCEEEECCHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCC
>Mature Secondary Structure 
ATAYQNLSEYDFNSVPDASEMNIGIVVAEWNKNITEKLLEGACNTLEKHGVKPENIVVK
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
RVPGSFELTFGAKRLAETKELDAVIVLGCVVRGDTPHFDYVCSGVTQGITELNLMYDIPF
ECCCCEEEECCHHHHHHHHHCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
IFGLLTTDTMQQSEDRAGGRYGNKGDEAAVTAIKMVNFSA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA