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The map label for this gene is cirA [H]

Identifier: 150006668

GI number: 150006668

Start: 5156508

End: 5158685

Strand: Reverse

Name: cirA [H]

Synonym: BVU_4189

Alternate gene names: 150006668

Gene position: 5158685-5156508 (Counterclockwise)

Preceding gene: 150006669

Following gene: 150006652

Centisome position: 99.91

GC content: 38.57

Gene sequence:

>2178_bases
ATGAAAATTAAATTAATAGCACTGGCAATAATTACATTGCTGGCACAAAGCATTTGTGCGCAAAACATATTTAAAGCAAT
CGTTAAAGACGGAGATACTAAAGAGATACTGGTTGGCGTGAATGCCGTTCTTAATAAAACCGCCAATGGAGCAAGCTCAG
ATGAAAACGGAATAATCACCATTTCGAACATACCTGACGGAAAGCAACATATCACATTCAGCTACTTAGGCTATGAATCG
GAAACCAAATCATACACATTCCCTTTATCTTCTTCAGCTCCGGTCGAAATCTTCTTGGAACAAGATGATGAAATGCTGGA
AGAAGTTACCATTTCTTCAACCAGAGGTACACGCACTATTCAAAACATCCCGACCCGTGTTGAATTTATTTCAAGCGAAG
AACTAGGAGAAAAAGGGAGCATGAAACCGGGCGACATTCGTATGTTACTAAACGAAAGCACAGGTATTATCACCCAGCAA
ACTTCTGCCACATCCGGAAATGCATCAATCCGCATACAAGGATTGGATGGCAGATATACACAAATATTAAAAGATGGATT
CCCCGTTTTTGCTGGTGCAGCGAGCGGACTGGGATTATTGCAAACGCCACCTCTTGACTTAAAACAAGTGGAAATCATCA
AAGGCTCAACTTCAACTTTATATGGCGGTGGAGCAATAGCAGGCTTGATTAATCTTATCTCAAAAACTCCCGAAGAGAAA
AGAGATTTAGGTCTGCATCTTAACGGGACATCCGGAAAAGGTTTGGACGTCAGCGCTTTCTATGGGCAACGATTCAAAAA
GGTCGGTACAACCATTTTTGCTTCCTACAACAGAAATTGGGCTTACGACCCCTCTAACACCGGATTCACAGCCATTCCGC
AGTTTGACAGATATGTCTTCAACCCCAAATTATTTCTCTATTTTTCAGAGAACACGCAAATGAGTGTAGGGCTAAATGCT
ATGTTTGAAGACCGTTTGGGCGGGGATATTGAGTATATTAAAGGAAATGGAAATGACACACATTCCTATTTCGAGAAAAA
CAAGACTCAAAGACATTCCACACAACTGACATTCGAACACAAATTCGGCGAAAAAGACAGAATTGATTTCAAAAACAGTG
TAACATACTTCAATAGAAATATCGGTGTACCCACTTATACTTTTGAAGGTACTCAGGTATCTACCTTTAGTGAATTGACT
TACACACGCACGAATCAAAAAACAGAATGGGTGGCTGGTCTCAACTTATGGACAGACAAATTTGATGAAAAGAAACTTAC
TGATTTTCAGTTAAGAGACTACAACCAGACAACCATGGGAGCATTCGTACAAAACAATTGGGAGGCAACAAAATGGTTGA
ATCTGGAAACCGGATTAAGAGCAGACTATATTCCGGATTATGGCGCAGCAATTCTACCACGAGTTTCTGCACATTTCAAA
ATTACGGATAAGTTTTCATCTCGACTTGGAGGAGGATTTGGCTATAAATCACCTACCATATTTACAGAGGATAGCGAAAG
GCTACAATATCAGAATGTATTGCCAATTGATAAAGACAATAACAAGCTCGAAAGAAGTTATGGTTTGAATTTAGACTTTA
ATTATGTCACATCAATCTTCGATGGAAATGTAACTTTCAGCATAAACCAATTATTCTTCTACACTTATCTCGATAATCCT
TTATTATTGCAATCTACAAAAGATGGGCTATATCGACTTAACAACATATCCGGCAATACAGATAGCAAAGGAGGAGAAAC
GAATGTAAAAATCGGATACAAAGATTTCCACTTATACTTAGGCTATACATACACCGATACCCGAACCAAAGAAAATGGGG
TGAAACAAGAGAATATATTAACTCCGAAACATAGGTTGAACAGTATTCTAATGTATGAAGTAGAAGATAAATGGAAAATA
GGATTAGAGGCTTATTATTTCAGCCCCCAAAAACTAGGAGACGGACAAAAAGGAAAACAATATGTGGTGTGCGGCTTCAT
GATTGAAAAAATATGGGAGATGTTTTCATTGTATGCTAACTTTGAAAACTTCACCGACAGACGGCAAACCCGCTTTGATA
CTATATATACCGGAAGTATATCTAATCCTGTTTTCCGGGATATTTATGCTCCTTTGGATGGATTTGTAATGAATGCGGGT
GTTAAACTCAGATTTTAA

Upstream 100 bases:

>100_bases
TAAATTCATGATGATGAAACCGCTGTTTCATCACCAGTACGTCGTGCACTTATTATAATACAGATTAAGTGTGTGGCACT
AAATTGACAAAACAAGAAAA

Downstream 100 bases:

>100_bases
ATTATAAAATAAACTCAAAATCAACAATAATATGAGAATTCTAGGAATAGCATTTACTTTAGTTTTATTGATGTCACTAG
TCGGATGTACTTTAAGCCAT

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MKIKLIALAIITLLAQSICAQNIFKAIVKDGDTKEILVGVNAVLNKTANGASSDENGIITISNIPDGKQHITFSYLGYES
ETKSYTFPLSSSAPVEIFLEQDDEMLEEVTISSTRGTRTIQNIPTRVEFISSEELGEKGSMKPGDIRMLLNESTGIITQQ
TSATSGNASIRIQGLDGRYTQILKDGFPVFAGAASGLGLLQTPPLDLKQVEIIKGSTSTLYGGGAIAGLINLISKTPEEK
RDLGLHLNGTSGKGLDVSAFYGQRFKKVGTTIFASYNRNWAYDPSNTGFTAIPQFDRYVFNPKLFLYFSENTQMSVGLNA
MFEDRLGGDIEYIKGNGNDTHSYFEKNKTQRHSTQLTFEHKFGEKDRIDFKNSVTYFNRNIGVPTYTFEGTQVSTFSELT
YTRTNQKTEWVAGLNLWTDKFDEKKLTDFQLRDYNQTTMGAFVQNNWEATKWLNLETGLRADYIPDYGAAILPRVSAHFK
ITDKFSSRLGGGFGYKSPTIFTEDSERLQYQNVLPIDKDNNKLERSYGLNLDFNYVTSIFDGNVTFSINQLFFYTYLDNP
LLLQSTKDGLYRLNNISGNTDSKGGETNVKIGYKDFHLYLGYTYTDTRTKENGVKQENILTPKHRLNSILMYEVEDKWKI
GLEAYYFSPQKLGDGQKGKQYVVCGFMIEKIWEMFSLYANFENFTDRRQTRFDTIYTGSISNPVFRDIYAPLDGFVMNAG
VKLRF

Sequences:

>Translated_725_residues
MKIKLIALAIITLLAQSICAQNIFKAIVKDGDTKEILVGVNAVLNKTANGASSDENGIITISNIPDGKQHITFSYLGYES
ETKSYTFPLSSSAPVEIFLEQDDEMLEEVTISSTRGTRTIQNIPTRVEFISSEELGEKGSMKPGDIRMLLNESTGIITQQ
TSATSGNASIRIQGLDGRYTQILKDGFPVFAGAASGLGLLQTPPLDLKQVEIIKGSTSTLYGGGAIAGLINLISKTPEEK
RDLGLHLNGTSGKGLDVSAFYGQRFKKVGTTIFASYNRNWAYDPSNTGFTAIPQFDRYVFNPKLFLYFSENTQMSVGLNA
MFEDRLGGDIEYIKGNGNDTHSYFEKNKTQRHSTQLTFEHKFGEKDRIDFKNSVTYFNRNIGVPTYTFEGTQVSTFSELT
YTRTNQKTEWVAGLNLWTDKFDEKKLTDFQLRDYNQTTMGAFVQNNWEATKWLNLETGLRADYIPDYGAAILPRVSAHFK
ITDKFSSRLGGGFGYKSPTIFTEDSERLQYQNVLPIDKDNNKLERSYGLNLDFNYVTSIFDGNVTFSINQLFFYTYLDNP
LLLQSTKDGLYRLNNISGNTDSKGGETNVKIGYKDFHLYLGYTYTDTRTKENGVKQENILTPKHRLNSILMYEVEDKWKI
GLEAYYFSPQKLGDGQKGKQYVVCGFMIEKIWEMFSLYANFENFTDRRQTRFDTIYTGSISNPVFRDIYAPLDGFVMNAG
VKLRF
>Mature_725_residues
MKIKLIALAIITLLAQSICAQNIFKAIVKDGDTKEILVGVNAVLNKTANGASSDENGIITISNIPDGKQHITFSYLGYES
ETKSYTFPLSSSAPVEIFLEQDDEMLEEVTISSTRGTRTIQNIPTRVEFISSEELGEKGSMKPGDIRMLLNESTGIITQQ
TSATSGNASIRIQGLDGRYTQILKDGFPVFAGAASGLGLLQTPPLDLKQVEIIKGSTSTLYGGGAIAGLINLISKTPEEK
RDLGLHLNGTSGKGLDVSAFYGQRFKKVGTTIFASYNRNWAYDPSNTGFTAIPQFDRYVFNPKLFLYFSENTQMSVGLNA
MFEDRLGGDIEYIKGNGNDTHSYFEKNKTQRHSTQLTFEHKFGEKDRIDFKNSVTYFNRNIGVPTYTFEGTQVSTFSELT
YTRTNQKTEWVAGLNLWTDKFDEKKLTDFQLRDYNQTTMGAFVQNNWEATKWLNLETGLRADYIPDYGAAILPRVSAHFK
ITDKFSSRLGGGFGYKSPTIFTEDSERLQYQNVLPIDKDNNKLERSYGLNLDFNYVTSIFDGNVTFSINQLFFYTYLDNP
LLLQSTKDGLYRLNNISGNTDSKGGETNVKIGYKDFHLYLGYTYTDTRTKENGVKQENILTPKHRLNSILMYEVEDKWKI
GLEAYYFSPQKLGDGQKGKQYVVCGFMIEKIWEMFSLYANFENFTDRRQTRFDTIYTGSISNPVFRDIYAPLDGFVMNAG
VKLRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=683, Percent_Identity=24.1581259150805, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81755; Mature: 81755

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKLIALAIITLLAQSICAQNIFKAIVKDGDTKEILVGVNAVLNKTANGASSDENGIIT
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEEE
ISNIPDGKQHITFSYLGYESETKSYTFPLSSSAPVEIFLEQDDEMLEEVTISSTRGTRTI
ECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCCCHH
QNIPTRVEFISSEELGEKGSMKPGDIRMLLNESTGIITQQTSATSGNASIRIQGLDGRYT
HCCCCEEEEECCHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCCHHH
QILKDGFPVFAGAASGLGLLQTPPLDLKQVEIIKGSTSTLYGGGAIAGLINLISKTPEEK
HHHHCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHCCCCHH
RDLGLHLNGTSGKGLDVSAFYGQRFKKVGTTIFASYNRNWAYDPSNTGFTAIPQFDRYVF
HCCCEEEECCCCCCEEEEHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEECCCCCCEEE
NPKLFLYFSENTQMSVGLNAMFEDRLGGDIEYIKGNGNDTHSYFEKNKTQRHSTQLTFEH
CCEEEEEECCCCEEEECCCEEEHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
KFGEKDRIDFKNSVTYFNRNIGVPTYTFEGTQVSTFSELTYTRTNQKTEWVAGLNLWTDK
CCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEEHHHEEEEECCCCCEEEEECCHHHCC
FDEKKLTDFQLRDYNQTTMGAFVQNNWEATKWLNLETGLRADYIPDYGAAILPRVSAHFK
CCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCEEE
ITDKFSSRLGGGFGYKSPTIFTEDSERLQYQNVLPIDKDNNKLERSYGLNLDFNYVTSIF
EEHHHHHHCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHEE
DGNVTFSINQLFFYTYLDNPLLLQSTKDGLYRLNNISGNTDSKGGETNVKIGYKDFHLYL
CCCEEEEEEEEEEEEECCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEEE
GYTYTDTRTKENGVKQENILTPKHRLNSILMYEVEDKWKIGLEAYYFSPQKLGDGQKGKQ
EEEEECCCCCCCCCCHHCCCCCHHHCCEEEEEEECCCEEEEEEEEEECHHHCCCCCCCCE
YVVCGFMIEKIWEMFSLYANFENFTDRRQTRFDTIYTGSISNPVFRDIYAPLDGFVMNAG
EEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEECC
VKLRF
EEEEC
>Mature Secondary Structure
MKIKLIALAIITLLAQSICAQNIFKAIVKDGDTKEILVGVNAVLNKTANGASSDENGIIT
CEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEEE
ISNIPDGKQHITFSYLGYESETKSYTFPLSSSAPVEIFLEQDDEMLEEVTISSTRGTRTI
ECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCCCCHH
QNIPTRVEFISSEELGEKGSMKPGDIRMLLNESTGIITQQTSATSGNASIRIQGLDGRYT
HCCCCEEEEECCHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCEEEEEECCCHHH
QILKDGFPVFAGAASGLGLLQTPPLDLKQVEIIKGSTSTLYGGGAIAGLINLISKTPEEK
HHHHCCCCEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHCCCCHH
RDLGLHLNGTSGKGLDVSAFYGQRFKKVGTTIFASYNRNWAYDPSNTGFTAIPQFDRYVF
HCCCEEEECCCCCCEEEEHHHHHHHHHHCCEEEEECCCCCCCCCCCCCEEECCCCCCEEE
NPKLFLYFSENTQMSVGLNAMFEDRLGGDIEYIKGNGNDTHSYFEKNKTQRHSTQLTFEH
CCEEEEEECCCCEEEECCCEEEHHCCCCCEEEEECCCCCHHHHHHHCCCCCCCEEEEEEE
KFGEKDRIDFKNSVTYFNRNIGVPTYTFEGTQVSTFSELTYTRTNQKTEWVAGLNLWTDK
CCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEEHHHEEEEECCCCCEEEEECCHHHCC
FDEKKLTDFQLRDYNQTTMGAFVQNNWEATKWLNLETGLRADYIPDYGAAILPRVSAHFK
CCCCCCCCEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCEEE
ITDKFSSRLGGGFGYKSPTIFTEDSERLQYQNVLPIDKDNNKLERSYGLNLDFNYVTSIF
EEHHHHHHCCCCCCCCCCEEEECCHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHEE
DGNVTFSINQLFFYTYLDNPLLLQSTKDGLYRLNNISGNTDSKGGETNVKIGYKDFHLYL
CCCEEEEEEEEEEEEECCCCEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEEEEEEEE
GYTYTDTRTKENGVKQENILTPKHRLNSILMYEVEDKWKIGLEAYYFSPQKLGDGQKGKQ
EEEEECCCCCCCCCCHHCCCCCHHHCCEEEEEEECCCEEEEEEEEEECHHHCCCCCCCCE
YVVCGFMIEKIWEMFSLYANFENFTDRRQTRFDTIYTGSISNPVFRDIYAPLDGFVMNAG
EEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEECC
VKLRF
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]