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The map label for this gene is srtF [H]

Identifier: 150006612

GI number: 150006612

Start: 5082306

End: 5082959

Strand: Direct

Name: srtF [H]

Synonym: BVU_4132

Alternate gene names: 150006612

Gene position: 5082306-5082959 (Clockwise)

Preceding gene: 150006611

Following gene: 150006626

Centisome position: 98.43

GC content: 38.38

Gene sequence:

>654_bases
ATGATAGAAGTGAATGATTTACATAAAAGTTTCGGTAAGGTCAAAGTATTAAACGGCATTCATTTGGAGTATCACCCTGG
AAAAATATATGGCTTGGTGGGCGAGAATGGAGCCGGAAAGACTACTTTATTCAATTGTATAATGGGAATCTATGATTATA
CCGGAAGCATAACCAAAAGCAAAACTTTAAAAACAGGTTATCTGTCTGCATCCAACTTCTTTTATTCCCAAATCACGGGT
CTTGAACACTTGGAATTCTGTATGAAGGCCAAAGGTCTGCCGGTCAATACACCCACCATTCAACATTTAAATGAAATTTT
CCAACTGCCCCTTGACAGGTATGCTGCCGAATATTCTACCGGAATGAAAAAGAAACTGGGATTTATGGCATTATTGTTGC
AAGACAATGACGTATTTATTCTTGACGAGCCGTTCAATGGGGTGGACTTGAAGGGATGTATCCTGATGAAAAGACTCATC
CGGCAACTGAAAGCAAAAGAAAAGACGGTGATAATTTCCTCACATCTCATTGCCTCGCTAAGGGAAATATGTGATATTAT
CCACTATCTGAACGAAGGGGGTATTTACAAAGAATACCATGAAGAAACAACAGAAGAGATAGAAGAGGATATATTATGCA
ATACTAAAAGCTGA

Upstream 100 bases:

>100_bases
TTTATTTAGGCTCTCTTTTTGTTCCAATTATTTTAATACCCGGCATAGCACTTACAGCATTGCTGACCTGCCATGCGCAC
AAACGCTTAAAAAGATTATT

Downstream 100 bases:

>100_bases
TTCATCTATCATGATGAAACAAATATAACAGTGGTTTTACCACTGAACTACCATGAAAAAATAGAATGAAAACCTAAAGA
AATATTTGTTCATAATGCAT

Product: ABC-type multidrug transport system, ATPase component

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MIEVNDLHKSFGKVKVLNGIHLEYHPGKIYGLVGENGAGKTTLFNCIMGIYDYTGSITKSKTLKTGYLSASNFFYSQITG
LEHLEFCMKAKGLPVNTPTIQHLNEIFQLPLDRYAAEYSTGMKKKLGFMALLLQDNDVFILDEPFNGVDLKGCILMKRLI
RQLKAKEKTVIISSHLIASLREICDIIHYLNEGGIYKEYHEETTEEIEEDILCNTKS

Sequences:

>Translated_217_residues
MIEVNDLHKSFGKVKVLNGIHLEYHPGKIYGLVGENGAGKTTLFNCIMGIYDYTGSITKSKTLKTGYLSASNFFYSQITG
LEHLEFCMKAKGLPVNTPTIQHLNEIFQLPLDRYAAEYSTGMKKKLGFMALLLQDNDVFILDEPFNGVDLKGCILMKRLI
RQLKAKEKTVIISSHLIASLREICDIIHYLNEGGIYKEYHEETTEEIEEDILCNTKS
>Mature_217_residues
MIEVNDLHKSFGKVKVLNGIHLEYHPGKIYGLVGENGAGKTTLFNCIMGIYDYTGSITKSKTLKTGYLSASNFFYSQITG
LEHLEFCMKAKGLPVNTPTIQHLNEIFQLPLDRYAAEYSTGMKKKLGFMALLLQDNDVFILDEPFNGVDLKGCILMKRLI
RQLKAKEKTVIISSHLIASLREICDIIHYLNEGGIYKEYHEETTEEIEEDILCNTKS

Specific function: Implicated in the export process of the lantibiotic SrtA (Potential) [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=179, Percent_Identity=30.7262569832402, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI153792144, Length=187, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=204, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI47078218, Length=204, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI150417984, Length=176, Percent_Identity=28.9772727272727, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27262624, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27262626, Length=222, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30795238, Length=188, Percent_Identity=28.1914893617021, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27477115, Length=179, Percent_Identity=30.1675977653631, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI6005701, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI21536376, Length=203, Percent_Identity=26.6009852216749, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788761, Length=214, Percent_Identity=28.0373831775701, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=211, Percent_Identity=25.5924170616114, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI48994943, Length=210, Percent_Identity=25.7142857142857, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1788165, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=206, Percent_Identity=25.7281553398058, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71983523, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=208, Percent_Identity=26.9230769230769, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565586, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650855, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650853, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221512771, Length=215, Percent_Identity=30.2325581395349, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666092, Length=209, Percent_Identity=29.1866028708134, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281362751, Length=205, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573571, Length=207, Percent_Identity=25.1207729468599, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221500365, Length=212, Percent_Identity=23.1132075471698, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI116007184, Length=212, Percent_Identity=23.1132075471698, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24643674, Length=207, Percent_Identity=25.1207729468599, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR022501
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 24548; Mature: 24548

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVNDLHKSFGKVKVLNGIHLEYHPGKIYGLVGENGAGKTTLFNCIMGIYDYTGSITKS
CCCCHHHHHHHCCEEEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
KTLKTGYLSASNFFYSQITGLEHLEFCMKAKGLPVNTPTIQHLNEIFQLPLDRYAAEYST
CCEECCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
GMKKKLGFMALLLQDNDVFILDEPFNGVDLKGCILMKRLIRQLKAKEKTVIISSHLIASL
CHHHHHHHEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
REICDIIHYLNEGGIYKEYHEETTEEIEEDILCNTKS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIEVNDLHKSFGKVKVLNGIHLEYHPGKIYGLVGENGAGKTTLFNCIMGIYDYTGSITKS
CCCCHHHHHHHCCEEEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCC
KTLKTGYLSASNFFYSQITGLEHLEFCMKAKGLPVNTPTIQHLNEIFQLPLDRYAAEYST
CCEECCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHC
GMKKKLGFMALLLQDNDVFILDEPFNGVDLKGCILMKRLIRQLKAKEKTVIISSHLIASL
CHHHHHHHEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
REICDIIHYLNEGGIYKEYHEETTEEIEEDILCNTKS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]