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The map label for this gene is resD [H]

Identifier: 150006575

GI number: 150006575

Start: 5037548

End: 5038237

Strand: Direct

Name: resD [H]

Synonym: BVU_4095

Alternate gene names: 150006575

Gene position: 5037548-5038237 (Clockwise)

Preceding gene: 150006574

Following gene: 150006576

Centisome position: 97.57

GC content: 42.03

Gene sequence:

>690_bases
ATGAATGATTACCGCATTTTAGTAGTTGACGATGAAGAAGATCTATGCGAGATTCTTAAATTCAATTTAGAAAACGAAGG
GTATTTTGTGGACACGGCAAACTCTGCCGAAGAAGCCCTGAAGATGGAACTGACCCAATACAACTTGCTGTTGCTGGATG
TGATGATGGGAGAAATATCAGGATTCAAAATGGCGAACATGCTGAAAAAGAATAAAGCTACTGCTTCTATTCCCATTATA
TTCATTACTGCTAAAGATACTGAAAACGATACCGTAACAGGGTTCAACTTGGGAGCCGACGACTATATCTCGAAGCCATT
TTCACTGCGCGAAGTTATAGCACGCGTTAAGGCTGTCCTTCGACGCACCAGTCCTACACAGGGAAAAGAAGCGCAAGAAC
AATTACAGTACAAAGGGCTTTTAGTCGACATAACCAAGAAGAAAGTCAGCATAGACGGTATAGAAATTTCCCTGACAAAA
AAAGAATTCGAAATCCTGTTGCTGTTGTTACAAAACAAAGGCCGCGTATTCTCACGCGAAGATATTCTGGCTAAAGTATG
GCAGGAGGAAGTCTATGTGCTGGACCGTACCATTGACGTCAACATTACCCGCTTGCGTAAAAAAATAGGCGAATATGGAA
AATGCATCGTCACCCGCCTGGGATACGGATACTGTTTTGAATGCGAATAA

Upstream 100 bases:

>100_bases
CTTTTTGTAATATTTGTTTCATCAAATAGTAATAAAAATGCTCCATTTTTGCAATGCTGATCAAAAAAGATTAGTTTTGT
AGTATTAAAAAGATGGATAT

Downstream 100 bases:

>100_bases
CCTAACCTGTACCTTTCCATGACTATTAAATTATCCAGCCACGTCCTGTCATTCAACAAGAAACTATTCTTGTCGGTAAT
TTCCTTATTCATAGCATTCG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNDYRILVVDDEEDLCEILKFNLENEGYFVDTANSAEEALKMELTQYNLLLLDVMMGEISGFKMANMLKKNKATASIPII
FITAKDTENDTVTGFNLGADDYISKPFSLREVIARVKAVLRRTSPTQGKEAQEQLQYKGLLVDITKKKVSIDGIEISLTK
KEFEILLLLLQNKGRVFSREDILAKVWQEEVYVLDRTIDVNITRLRKKIGEYGKCIVTRLGYGYCFECE

Sequences:

>Translated_229_residues
MNDYRILVVDDEEDLCEILKFNLENEGYFVDTANSAEEALKMELTQYNLLLLDVMMGEISGFKMANMLKKNKATASIPII
FITAKDTENDTVTGFNLGADDYISKPFSLREVIARVKAVLRRTSPTQGKEAQEQLQYKGLLVDITKKKVSIDGIEISLTK
KEFEILLLLLQNKGRVFSREDILAKVWQEEVYVLDRTIDVNITRLRKKIGEYGKCIVTRLGYGYCFECE
>Mature_229_residues
MNDYRILVVDDEEDLCEILKFNLENEGYFVDTANSAEEALKMELTQYNLLLLDVMMGEISGFKMANMLKKNKATASIPII
FITAKDTENDTVTGFNLGADDYISKPFSLREVIARVKAVLRRTSPTQGKEAQEQLQYKGLLVDITKKKVSIDGIEISLTK
KEFEILLLLLQNKGRVFSREDILAKVWQEEVYVLDRTIDVNITRLRKKIGEYGKCIVTRLGYGYCFECE

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=39.1111111111111, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.6828193832599, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=35.1111111111111, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.117903930131, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=232, Percent_Identity=35.7758620689655, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=32.7586206896552, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=31.5555555555556, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.4561403508772, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=32.6271186440678, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=32, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=32.8947368421053, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=32.0175438596491, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=28.4444444444444, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=36.6666666666667, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26203; Mature: 26203

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYRILVVDDEEDLCEILKFNLENEGYFVDTANSAEEALKMELTQYNLLLLDVMMGEIS
CCCEEEEEEECCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GFKMANMLKKNKATASIPIIFITAKDTENDTVTGFNLGADDYISKPFSLREVIARVKAVL
CHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHH
RRTSPTQGKEAQEQLQYKGLLVDITKKKVSIDGIEISLTKKEFEILLLLLQNKGRVFSRE
HCCCCCCCHHHHHHHHHCCEEEEEECCEEEECCEEEEEEHHHHHEEEEEECCCCCEECHH
DILAKVWQEEVYVLDRTIDVNITRLRKKIGEYGKCIVTRLGYGYCFECE
HHHHHHHHHHEEEEEEEECCHHHHHHHHHCHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MNDYRILVVDDEEDLCEILKFNLENEGYFVDTANSAEEALKMELTQYNLLLLDVMMGEIS
CCCEEEEEEECCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GFKMANMLKKNKATASIPIIFITAKDTENDTVTGFNLGADDYISKPFSLREVIARVKAVL
CHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHHHHH
RRTSPTQGKEAQEQLQYKGLLVDITKKKVSIDGIEISLTKKEFEILLLLLQNKGRVFSRE
HCCCCCCCHHHHHHHHHCCEEEEEECCEEEECCEEEEEEHHHHHEEEEEECCCCCEECHH
DILAKVWQEEVYVLDRTIDVNITRLRKKIGEYGKCIVTRLGYGYCFECE
HHHHHHHHHHEEEEEEEECCHHHHHHHHHCHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]