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The map label for this gene is glmS [H]

Identifier: 150006481

GI number: 150006481

Start: 4925272

End: 4927116

Strand: Reverse

Name: glmS [H]

Synonym: BVU_4000

Alternate gene names: 150006481

Gene position: 4927116-4925272 (Counterclockwise)

Preceding gene: 150006482

Following gene: 150006480

Centisome position: 95.43

GC content: 45.37

Gene sequence:

>1845_bases
ATGTGTGGAATAGTAGGCTATATTGGAAAACGAGATGCTTACCCTGTTCTCATAAAAGGCCTGAAGCGGTTGGAATACCG
GGGCTATGATAGCGCAGGAGTCGCATTGATAGACAAAAAAAGGAGGTTGAACGTTTATAAAACGAAAGGAAAGGTTTCAG
ACCTAGAGGCTTTTGTTTCCCAAAAAGACGTTTCCGGTACAATTGGTATTGCCCACACCCGATGGGCCACCCACGGAGAG
CCTTGTCAGGCTAACGCTCATCCTCATTTTTCTTCTTCAAAGAATCTAGCTCTTATCCACAATGGTATTATTGAAAACTA
CGCTACCCTGAAAGAAAAGCTACAAAAAAAAGGGTTCATCTTTAAAAGTAGTACAGATACCGAAGTTCTCGTACAGTTAA
TTGAATTTTTCCAACTTTCCAACCATTTAGATTTACTTACTGCCGTTCAGTTGGCTCTGCATGAGGTGATTGGCGCATAC
GCTATAGCGGTGCTCGACAAGAATAATCCCGATGAGATTATTGCAGCACGCAAAAGCAGTCCGCTGGTGGTAGGGATAGG
GAAGGATGAATTCTTTCTGGCTTCGGATGCTACTCCGATTGTAGAGTATACGGATAAAGTGGTGTATCTGCAAGATGGGG
AGATAGCGGTGATTCGCAGAGACAAGACATTGGAAGTCGTCAATCTGGACAACGTGCTTCAAAATCCCGAAGTACGTACG
GTGGAAATGAATCTGGGACAACTGGAGAAAGGGGGATACCCGCATTTCATGTTGAAGGAGATATTCGAACAACCCGATTG
TATTAACGACTGTATGCGTGGACGCATCAATGCGGACGGTGATAAAGTAGTACTGTCGGCGGTTATTGATCATAAGGAAC
GTCTGCTCAAGGCTCGTCGCTTTGTAATTGTGGCTTGCGGAACTTCGTGGCATGCCGGATTGATAGGGAAACAACTGATA
GAAAGTTTCTGCCGTATTCCGGTAGAAGTGGAATATGCCTCCGAGTTCCGCTATCGTGATCCGGTGATTCATGAAGACGA
TGTGGTAATAGCTATCTCGCAATCGGGTGAAACGGCCGATACATTGGCTGCCATAGAACTGGCGAAAGAGAAAGGAGCTT
TTATCTATGGTATATGCAATGCGGTAGGTTCATCCATTCCGCGCATTACAGATACCGGTTCTTATATTCATGTAGGACCG
GAAATAGGAGTGGCGTCCACCAAGGCATTTACCGGACAGGTAACCGTGCTTACCATGCTGGCGCTGACGCTGGCAAAAGA
GAAAGGGAGTATGGCAGATGAGAAATACCTGGAAGTGATCCGGGAATTGACTGTGATTCCGGCTAAAATAAAAAAGATAT
TGATCAGTAATCCTAAAATAGCGGAACTGTCGCGTATTTTCACCTATGCACATAATTTCCTCTATTTGGGACGGGGCTAC
AGTTTCCCGGTAGCTTTGGAAGGTGCGTTAAAGTTGAAGGAGATATCTTATATTCACGCTGAAGGCTATCCCGCAGCCGA
GATGAAACATGGGCCTATCGCATTGATTGATGCCGAAATGCCTGTTGTGGTGATAGCTACGCATAATGCGATGTATGAAA
AGATAATGAGTAACATACAGGAAATCAAGGCGCGGAAGGGAAAAGTAATCGCTTTGGTCACAGAAGGAGATACGGTAATC
GGTAAGTTGGCCGATGATTGCATTGAGTTGCCCGAAACATTAGAGTGCCTCGAACCGTTGATAGCTACGGTCCCCTTACA
GTTATTGGCCTACCATGTAGCCATTTGCAAAGGGAAGAATGTGGATCAGCCACGAAATCTGGCGAAGTCGGTAACAGTAG
AATAG

Upstream 100 bases:

>100_bases
TTTTTATCGCTTTCGTCAATTATTTATGGTTTTTTATTGCATTTATGTTAATTGATATTTGTATCTTTGCAGTCGAATCA
GAACATATACTTAGTAGATT

Downstream 100 bases:

>100_bases
AAGGCAATGCTGCCGGAGATTATGCAGGAAGTTTCCGGCATAATTCTTGAAAGATGTACCGTAAGTTTGGAAAAATGACA
GAAGGTCTTGTCATACCTTT

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MCGIVGYIGKRDAYPVLIKGLKRLEYRGYDSAGVALIDKKRRLNVYKTKGKVSDLEAFVSQKDVSGTIGIAHTRWATHGE
PCQANAHPHFSSSKNLALIHNGIIENYATLKEKLQKKGFIFKSSTDTEVLVQLIEFFQLSNHLDLLTAVQLALHEVIGAY
AIAVLDKNNPDEIIAARKSSPLVVGIGKDEFFLASDATPIVEYTDKVVYLQDGEIAVIRRDKTLEVVNLDNVLQNPEVRT
VEMNLGQLEKGGYPHFMLKEIFEQPDCINDCMRGRINADGDKVVLSAVIDHKERLLKARRFVIVACGTSWHAGLIGKQLI
ESFCRIPVEVEYASEFRYRDPVIHEDDVVIAISQSGETADTLAAIELAKEKGAFIYGICNAVGSSIPRITDTGSYIHVGP
EIGVASTKAFTGQVTVLTMLALTLAKEKGSMADEKYLEVIRELTVIPAKIKKILISNPKIAELSRIFTYAHNFLYLGRGY
SFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDAEMPVVVIATHNAMYEKIMSNIQEIKARKGKVIALVTEGDTVI
GKLADDCIELPETLECLEPLIATVPLQLLAYHVAICKGKNVDQPRNLAKSVTVE

Sequences:

>Translated_614_residues
MCGIVGYIGKRDAYPVLIKGLKRLEYRGYDSAGVALIDKKRRLNVYKTKGKVSDLEAFVSQKDVSGTIGIAHTRWATHGE
PCQANAHPHFSSSKNLALIHNGIIENYATLKEKLQKKGFIFKSSTDTEVLVQLIEFFQLSNHLDLLTAVQLALHEVIGAY
AIAVLDKNNPDEIIAARKSSPLVVGIGKDEFFLASDATPIVEYTDKVVYLQDGEIAVIRRDKTLEVVNLDNVLQNPEVRT
VEMNLGQLEKGGYPHFMLKEIFEQPDCINDCMRGRINADGDKVVLSAVIDHKERLLKARRFVIVACGTSWHAGLIGKQLI
ESFCRIPVEVEYASEFRYRDPVIHEDDVVIAISQSGETADTLAAIELAKEKGAFIYGICNAVGSSIPRITDTGSYIHVGP
EIGVASTKAFTGQVTVLTMLALTLAKEKGSMADEKYLEVIRELTVIPAKIKKILISNPKIAELSRIFTYAHNFLYLGRGY
SFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDAEMPVVVIATHNAMYEKIMSNIQEIKARKGKVIALVTEGDTVI
GKLADDCIELPETLECLEPLIATVPLQLLAYHVAICKGKNVDQPRNLAKSVTVE
>Mature_614_residues
MCGIVGYIGKRDAYPVLIKGLKRLEYRGYDSAGVALIDKKRRLNVYKTKGKVSDLEAFVSQKDVSGTIGIAHTRWATHGE
PCQANAHPHFSSSKNLALIHNGIIENYATLKEKLQKKGFIFKSSTDTEVLVQLIEFFQLSNHLDLLTAVQLALHEVIGAY
AIAVLDKNNPDEIIAARKSSPLVVGIGKDEFFLASDATPIVEYTDKVVYLQDGEIAVIRRDKTLEVVNLDNVLQNPEVRT
VEMNLGQLEKGGYPHFMLKEIFEQPDCINDCMRGRINADGDKVVLSAVIDHKERLLKARRFVIVACGTSWHAGLIGKQLI
ESFCRIPVEVEYASEFRYRDPVIHEDDVVIAISQSGETADTLAAIELAKEKGAFIYGICNAVGSSIPRITDTGSYIHVGP
EIGVASTKAFTGQVTVLTMLALTLAKEKGSMADEKYLEVIRELTVIPAKIKKILISNPKIAELSRIFTYAHNFLYLGRGY
SFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDAEMPVVVIATHNAMYEKIMSNIQEIKARKGKVIALVTEGDTVI
GKLADDCIELPETLECLEPLIATVPLQLLAYHVAICKGKNVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=39.5620437956204, Blast_Score=505, Evalue=1e-143,
Organism=Homo sapiens, GI205277386, Length=683, Percent_Identity=39.8243045387994, Blast_Score=490, Evalue=1e-138,
Organism=Escherichia coli, GI1790167, Length=622, Percent_Identity=45.6591639871383, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1788651, Length=173, Percent_Identity=30.635838150289, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17532899, Length=433, Percent_Identity=42.2632794457275, Blast_Score=349, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI17532897, Length=433, Percent_Identity=42.2632794457275, Blast_Score=348, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI17539970, Length=433, Percent_Identity=40.1847575057737, Blast_Score=331, Evalue=9e-91,
Organism=Saccharomyces cerevisiae, GI6322745, Length=433, Percent_Identity=44.1108545034642, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6323731, Length=429, Percent_Identity=37.995337995338, Blast_Score=280, Evalue=6e-76,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=40, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6323958, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357745, Length=684, Percent_Identity=39.6198830409357, Blast_Score=513, Evalue=1e-145,
Organism=Drosophila melanogaster, GI28573187, Length=142, Percent_Identity=33.0985915492958, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67639; Mature: 67639

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGKRDAYPVLIKGLKRLEYRGYDSAGVALIDKKRRLNVYKTKGKVSDLEAFVS
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHH
QKDVSGTIGIAHTRWATHGEPCQANAHPHFSSSKNLALIHNGIIENYATLKEKLQKKGFI
HCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCE
FKSSTDTEVLVQLIEFFQLSNHLDLLTAVQLALHEVIGAYAIAVLDKNNPDEIIAARKSS
EECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHEEEECCCC
PLVVGIGKDEFFLASDATPIVEYTDKVVYLQDGEIAVIRRDKTLEVVNLDNVLQNPEVRT
CEEEEECCCCEEEECCCCCCEECCCEEEEEECCCEEEEECCCEEEEEEHHHHHCCCCEEE
VEMNLGQLEKGGYPHFMLKEIFEQPDCINDCMRGRINADGDKVVLSAVIDHKERLLKARR
EEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCE
FVIVACGTSWHAGLIGKQLIESFCRIPVEVEYASEFRYRDPVIHEDDVVIAISQSGETAD
EEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCEEEEEECCCCCHH
TLAAIELAKEKGAFIYGICNAVGSSIPRITDTGSYIHVGPEIGVASTKAFTGQVTVLTML
HHHHHHHHHHCCCEEEEEHHHHCCCCCCEECCCCEEEECCCCCCCCCCCCCCHHHHHHHH
ALTLAKEKGSMADEKYLEVIRELTVIPAKIKKILISNPKIAELSRIFTYAHNFLYLGRGY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEECCCC
SFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDAEMPVVVIATHNAMYEKIMSNIQ
CCCEEECCCEEEEHEEEEECCCCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHH
EIKARKGKVIALVTEGDTVIGKLADDCIELPETLECLEPLIATVPLQLLAYHVAICKGKN
HHHHCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGKRDAYPVLIKGLKRLEYRGYDSAGVALIDKKRRLNVYKTKGKVSDLEAFVS
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHH
QKDVSGTIGIAHTRWATHGEPCQANAHPHFSSSKNLALIHNGIIENYATLKEKLQKKGFI
HCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCE
FKSSTDTEVLVQLIEFFQLSNHLDLLTAVQLALHEVIGAYAIAVLDKNNPDEIIAARKSS
EECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHEEEECCCC
PLVVGIGKDEFFLASDATPIVEYTDKVVYLQDGEIAVIRRDKTLEVVNLDNVLQNPEVRT
CEEEEECCCCEEEECCCCCCEECCCEEEEEECCCEEEEECCCEEEEEEHHHHHCCCCEEE
VEMNLGQLEKGGYPHFMLKEIFEQPDCINDCMRGRINADGDKVVLSAVIDHKERLLKARR
EEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCE
FVIVACGTSWHAGLIGKQLIESFCRIPVEVEYASEFRYRDPVIHEDDVVIAISQSGETAD
EEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCCEEEEEECCCCCHH
TLAAIELAKEKGAFIYGICNAVGSSIPRITDTGSYIHVGPEIGVASTKAFTGQVTVLTML
HHHHHHHHHHCCCEEEEEHHHHCCCCCCEECCCCEEEECCCCCCCCCCCCCCHHHHHHHH
ALTLAKEKGSMADEKYLEVIRELTVIPAKIKKILISNPKIAELSRIFTYAHNFLYLGRGY
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEEECCCC
SFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDAEMPVVVIATHNAMYEKIMSNIQ
CCCEEECCCEEEEHEEEEECCCCCCCCCCCCCEEEEECCCCEEEEEECHHHHHHHHHHHH
EIKARKGKVIALVTEGDTVIGKLADDCIELPETLECLEPLIATVPLQLLAYHVAICKGKN
HHHHCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VDQPRNLAKSVTVE
CCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]