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The map label for this gene is glnS [H]

Identifier: 150006422

GI number: 150006422

Start: 4854486

End: 4856225

Strand: Direct

Name: glnS [H]

Synonym: BVU_3941

Alternate gene names: 150006422

Gene position: 4854486-4856225 (Clockwise)

Preceding gene: 150006421

Following gene: 150006423

Centisome position: 94.02

GC content: 50.23

Gene sequence:

>1740_bases
ATGACTGAAATGAACGCTACAGAAGCTACAGAGAAGAAAAGTCTGAACTTCATTGAACAGGCAGTTGAGAACGACCTGAG
AGAAGGTAAAAACGGAGGGAAAGTACAAACCCGCTTTCCGCCCGAGCCGAACGGCTACCTGCACATCGGTCATGCCAAAG
CCATCTGTCTGGATTTCGGGATAGCTGCACGCTATGGTGGCGTATGTAACCTGCGTTTTGACGACACCAACCCGACCAAA
GAAGATATGGAATACGTGGAAGCCATCAAGGAGGACATCCAATGGCTCGGATTCCAGTGGGGAAACGAATATTATGCATC
CGACTACTTCCAGCAATTATGGGATTTCGCCGTCAATCTGATAAAGGAAGGAAAGGCTTATATAGACGAACAGAACTCCG
AACAAATCGCGGCACAAAAAGGCACTCCCACCCAACCCGGAACCGAGAGTCCTTACCGCAACCGTCCCATCGAGGAAAGC
CTGGAACTGTTCAACAAAATGAACAGCGGTGAAATAGAAGAAGGCAAAATGGTGCTCCGTGCCAAAATAGACATGGCAAG
CCCCAACATGCACTTCCGCGACCCTATTATTTATCGTGTGGTAAAGACTCCGCACCACCGTACAGGCGAAACCTGGAAAG
CATACCCCATGTATGACTTTGCACACGGACAGAGCGACTATTTTGAAGGAGTGACCCATTCGCTGTGTACCCTGGAGTTC
GTACCCCACCGTCCGTTGTACGACCTGTTCGTGGACTGGGTAAAAGAGGGTAAAGATCTGGACGACAACCGTCCTCATCA
GTATGAGTTCAACAAACTGAACCTGAACTACACCTTGATGAGCAAGCGTAACCTGCTGATTCTGGTAAAAGAACATCTGG
TAAACGGTTGGGACGACCCCCGTATGCCGACTCTCTGCGGTTTCCGCCGTCGCGGCTACTCGCCTGAGTCCATCCGCAAA
TTTGTAGACAAGATAGGTTATACCACTTACGATGCCCTGAATGACTTCGCCCTGCTGGAAAGTGCTGTCCGCGAAGACTT
GAACAGCCGTGCCACCCGTGTATCGGCAGTCATCAATCCGGTGAAACTGATCATTACCAACTATCCCGAAGGACAGGTGG
AGGAAATGGAAGCTGTCAACAACCCGGAAGATCCGTCGGCAGGCACACACACCATCGAATTCAGCCGCGAACTGTGGATA
GAACGCGACGACTTCATGGAAGACGCCCCGAAGAAATATTTCCGTATGACTCCGGGACAGGAAGTGCGTCTGAAAAGCGG
ATACATCGTGAAATGCACAGGCTGCAAGAAAGACGACAACGGCAACGTGGTGGAGGTATACTGCGAATACGATCCCGACA
GCAAAACAGGTATGCCGGGCAGCAACCGCAAAATCAAAGGTACCATCCACTGGGTAAGCTGCGCACACTGTCTGCCTGCC
GAAGTACGCCTGTACGACCGCCTGTGGAAAGTGGAGAACCCGCGTGATGAGATGGCCGCCATCCGCGAAGCAAAGAACTG
CGACGCACTGGAAGCCATGAAAGAAATGATCAACCCCGATTCGTTGAATGTATTAACCAACTGCTATGTAGAGAAATATC
TGGCCGATGCCAAACCGCTGGATTACTTGCAGTTCCAACGCATCGGTTATTTCAATGTAGACAAAGACTCTACACCGGAA
CATCTGGTGTTCAACCGCACCGTATCTTTAAAAGATACCTGGAGCAAAATCAATAAATAA

Upstream 100 bases:

>100_bases
GCAAAATATTATAAAAAACGGTGGATATATTCCTGTGAAATAAAGGATATCCCAAAAAGAATGCGTACTTTTGCAGCAAA
AGTGTAAAATTGATATCACA

Downstream 100 bases:

>100_bases
AAACAAGCTTATGAACTACGACATGTCTTCTTACTTTGAAGACCCGGAATTTAAAGAAGCATTGGCAAAATACGAGGGTA
TGGTGGAGAACCATACCCCC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MTEMNATEATEKKSLNFIEQAVENDLREGKNGGKVQTRFPPEPNGYLHIGHAKAICLDFGIAARYGGVCNLRFDDTNPTK
EDMEYVEAIKEDIQWLGFQWGNEYYASDYFQQLWDFAVNLIKEGKAYIDEQNSEQIAAQKGTPTQPGTESPYRNRPIEES
LELFNKMNSGEIEEGKMVLRAKIDMASPNMHFRDPIIYRVVKTPHHRTGETWKAYPMYDFAHGQSDYFEGVTHSLCTLEF
VPHRPLYDLFVDWVKEGKDLDDNRPHQYEFNKLNLNYTLMSKRNLLILVKEHLVNGWDDPRMPTLCGFRRRGYSPESIRK
FVDKIGYTTYDALNDFALLESAVREDLNSRATRVSAVINPVKLIITNYPEGQVEEMEAVNNPEDPSAGTHTIEFSRELWI
ERDDFMEDAPKKYFRMTPGQEVRLKSGYIVKCTGCKKDDNGNVVEVYCEYDPDSKTGMPGSNRKIKGTIHWVSCAHCLPA
EVRLYDRLWKVENPRDEMAAIREAKNCDALEAMKEMINPDSLNVLTNCYVEKYLADAKPLDYLQFQRIGYFNVDKDSTPE
HLVFNRTVSLKDTWSKINK

Sequences:

>Translated_579_residues
MTEMNATEATEKKSLNFIEQAVENDLREGKNGGKVQTRFPPEPNGYLHIGHAKAICLDFGIAARYGGVCNLRFDDTNPTK
EDMEYVEAIKEDIQWLGFQWGNEYYASDYFQQLWDFAVNLIKEGKAYIDEQNSEQIAAQKGTPTQPGTESPYRNRPIEES
LELFNKMNSGEIEEGKMVLRAKIDMASPNMHFRDPIIYRVVKTPHHRTGETWKAYPMYDFAHGQSDYFEGVTHSLCTLEF
VPHRPLYDLFVDWVKEGKDLDDNRPHQYEFNKLNLNYTLMSKRNLLILVKEHLVNGWDDPRMPTLCGFRRRGYSPESIRK
FVDKIGYTTYDALNDFALLESAVREDLNSRATRVSAVINPVKLIITNYPEGQVEEMEAVNNPEDPSAGTHTIEFSRELWI
ERDDFMEDAPKKYFRMTPGQEVRLKSGYIVKCTGCKKDDNGNVVEVYCEYDPDSKTGMPGSNRKIKGTIHWVSCAHCLPA
EVRLYDRLWKVENPRDEMAAIREAKNCDALEAMKEMINPDSLNVLTNCYVEKYLADAKPLDYLQFQRIGYFNVDKDSTPE
HLVFNRTVSLKDTWSKINK
>Mature_578_residues
TEMNATEATEKKSLNFIEQAVENDLREGKNGGKVQTRFPPEPNGYLHIGHAKAICLDFGIAARYGGVCNLRFDDTNPTKE
DMEYVEAIKEDIQWLGFQWGNEYYASDYFQQLWDFAVNLIKEGKAYIDEQNSEQIAAQKGTPTQPGTESPYRNRPIEESL
ELFNKMNSGEIEEGKMVLRAKIDMASPNMHFRDPIIYRVVKTPHHRTGETWKAYPMYDFAHGQSDYFEGVTHSLCTLEFV
PHRPLYDLFVDWVKEGKDLDDNRPHQYEFNKLNLNYTLMSKRNLLILVKEHLVNGWDDPRMPTLCGFRRRGYSPESIRKF
VDKIGYTTYDALNDFALLESAVREDLNSRATRVSAVINPVKLIITNYPEGQVEEMEAVNNPEDPSAGTHTIEFSRELWIE
RDDFMEDAPKKYFRMTPGQEVRLKSGYIVKCTGCKKDDNGNVVEVYCEYDPDSKTGMPGSNRKIKGTIHWVSCAHCLPAE
VRLYDRLWKVENPRDEMAAIREAKNCDALEAMKEMINPDSLNVLTNCYVEKYLADAKPLDYLQFQRIGYFNVDKDSTPEH
LVFNRTVSLKDTWSKINK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=567, Percent_Identity=41.9753086419753, Blast_Score=411, Evalue=1e-114,
Organism=Homo sapiens, GI62241042, Length=535, Percent_Identity=33.0841121495327, Blast_Score=255, Evalue=1e-67,
Organism=Escherichia coli, GI1786895, Length=572, Percent_Identity=52.7972027972028, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1788743, Length=351, Percent_Identity=22.7920227920228, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=547, Percent_Identity=43.1444241316271, Blast_Score=412, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=541, Percent_Identity=29.3900184842884, Blast_Score=216, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324742, Length=570, Percent_Identity=39.2982456140351, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321192, Length=561, Percent_Identity=34.0463458110517, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI17864488, Length=563, Percent_Identity=41.3854351687389, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24649466, Length=376, Percent_Identity=36.7021276595745, Blast_Score=240, Evalue=2e-63,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 66873; Mature: 66742

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEMNATEATEKKSLNFIEQAVENDLREGKNGGKVQTRFPPEPNGYLHIGHAKAICLDFG
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCEEEEEHHH
IAARYGGVCNLRFDDTNPTKEDMEYVEAIKEDIQWLGFQWGNEYYASDYFQQLWDFAVNL
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHH
IKEGKAYIDEQNSEQIAAQKGTPTQPGTESPYRNRPIEESLELFNKMNSGEIEEGKMVLR
HHCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
AKIDMASPNMHFRDPIIYRVVKTPHHRTGETWKAYPMYDFAHGQSDYFEGVTHSLCTLEF
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCHHCCCCCHHHHHHHHHHEEEEE
VPHRPLYDLFVDWVKEGKDLDDNRPHQYEFNKLNLNYTLMSKRNLLILVKEHLVNGWDDP
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEHHHCCCCCCC
RMPTLCGFRRRGYSPESIRKFVDKIGYTTYDALNDFALLESAVREDLNSRATRVSAVINP
CCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VKLIITNYPEGQVEEMEAVNNPEDPSAGTHTIEFSRELWIERDDFMEDAPKKYFRMTPGQ
EEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHEECCCCC
EVRLKSGYIVKCTGCKKDDNGNVVEVYCEYDPDSKTGMPGSNRKIKGTIHWVSCAHCLPA
CEEECCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEHHHHCCH
EVRLYDRLWKVENPRDEMAAIREAKNCDALEAMKEMINPDSLNVLTNCYVEKYLADAKPL
HHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
DYLQFQRIGYFNVDKDSTPEHLVFNRTVSLKDTWSKINK
CHHHHHHCCEEECCCCCCCCEEEEEEEECCHHHHHHHCC
>Mature Secondary Structure 
TEMNATEATEKKSLNFIEQAVENDLREGKNGGKVQTRFPPEPNGYLHIGHAKAICLDFG
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECCCEEEEEHHH
IAARYGGVCNLRFDDTNPTKEDMEYVEAIKEDIQWLGFQWGNEYYASDYFQQLWDFAVNL
HHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHH
IKEGKAYIDEQNSEQIAAQKGTPTQPGTESPYRNRPIEESLELFNKMNSGEIEEGKMVLR
HHCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEE
AKIDMASPNMHFRDPIIYRVVKTPHHRTGETWKAYPMYDFAHGQSDYFEGVTHSLCTLEF
EEEECCCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCHHCCCCCHHHHHHHHHHEEEEE
VPHRPLYDLFVDWVKEGKDLDDNRPHQYEFNKLNLNYTLMSKRNLLILVKEHLVNGWDDP
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEEEEHHHCCCCCCC
RMPTLCGFRRRGYSPESIRKFVDKIGYTTYDALNDFALLESAVREDLNSRATRVSAVINP
CCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VKLIITNYPEGQVEEMEAVNNPEDPSAGTHTIEFSRELWIERDDFMEDAPKKYFRMTPGQ
EEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHEECCCCC
EVRLKSGYIVKCTGCKKDDNGNVVEVYCEYDPDSKTGMPGSNRKIKGTIHWVSCAHCLPA
CEEECCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEHHHHCCH
EVRLYDRLWKVENPRDEMAAIREAKNCDALEAMKEMINPDSLNVLTNCYVEKYLADAKPL
HHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
DYLQFQRIGYFNVDKDSTPEHLVFNRTVSLKDTWSKINK
CHHHHHHCCEEECCCCCCCCEEEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12835416 [H]