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The map label for this gene is clpB [H]

Identifier: 150006304

GI number: 150006304

Start: 4713711

End: 4716299

Strand: Direct

Name: clpB [H]

Synonym: BVU_3815

Alternate gene names: 150006304

Gene position: 4713711-4716299 (Clockwise)

Preceding gene: 150006300

Following gene: 150006305

Centisome position: 91.29

GC content: 46.04

Gene sequence:

>2589_bases
ATGAATTTTAACAACTTCACAATTAAATCACAGGAGGCAGTGCAACAAGCGGTGAACATAACTCAAGCCCGCGGACAGCA
AGCTATCGAGCCTGTGCATCTGTTGGCCGGAGTACTGAAAGTAGGTGAAAACGTCACCAACTTCATTTTCCAGAAATTGG
GAATGAACGCCCAGCAGATCGCATTGGTCATCGACAAGCAAATTGACTCGCTGCCTAAGGTTTCGGGAGGAGAACCTTAC
CTTAGCCGTGAAAGCAACGAGATATTACAAAGAGCCGTACAGTATTCCAAAGAGATGGGTGACGAATTCGTTTCACTGGA
AGCTATTATCCTAGCCTTGTTGAATGTAAAGAGTACTGTCGCTACCATATTGAAAGACGCGGGAATGACAGACAAAGAGC
TGCGCTCCGCCATAGCAGAACTACGTAAAGGTGAAAAAGTAACTTCACAATCCAGTGAAGACACTTATCAATCCTTAAGC
AAATATGCCATTAATTTGAATGAGGCTGCCCGCAGCGGAAAACTTGATCCGGTTATCGGGCGTGATGAAGAAATACGTAG
GGTATTACAAATATTAAGCCGCCGTACCAAGAATAATCCGATTTTAATCGGTGAGCCGGGTACCGGTAAGACCGCCATTG
TTGAAGGCTTGGCACACCGTATCATCCGAGGTGATGTACCCGACAACTTGAAGAACAAACAAATCTTCTCATTGGATATG
GGCGCACTGGTTGCCGGAGCCAAATACAAAGGTGAATTTGAAGAACGTCTGAAATCTGTTGTCAATGAAGTAATCAAAGC
CGAAGGCAGCATCATCCTGTTTATCGATGAAATCCATACCTTGGTCGGAGCCGGTAAAGGTGAAGGTGCCATGGATGCCG
CCAATATATTAAAACCCGCCTTGGCCCGTGGTGAGCTCCGCAGCATCGGAGCCACTACTTTGGACGAATATCAGAAGTAC
TTCGAAAAGGACAAGGCATTGGAACGCCGGTTCCAAACCGTTATGGTAGCCGAACCGGACACGCTGAGCACCATCTCCAT
TCTCCGTGGATTGAAAGAACGTTACGAAAACCATCACAAGGTACGTATCAAAGATGAAGCCATCATTGCCGCTGTAGAAT
TGAGTAACCGTTACATTACCGAACGTTTCCTTCCGGACAAGGCTATTGACCTGATGGATGAAGCTGCTGCCAAATTGCGT
ATGGAACGTGATTCCGTGCCTGAAGAACTGGATGAAATCTCACGTCACCTGAAACAACTGGAAATTGAACGTGAGGCCAT
CAAACGTGAAAAAGACGAGCCGAAATTACAACAACTGAATAAAGAGATTGCCGAACTGAAAGAACAGGAAACCTCTTACA
AAGCCAAATGGCAGAGTGAAAAGGAACTGGTCAACAAGATTCAGCAAAACAAGCAGGAAATAGAACAATTGAAATTTGAA
GCCGAGAAAGCGGAACGTGAGGGAGATTACGGTAAAGTAGCCGAAATCCGTTATGGAAAATTACAGGCTTTAGAGAACGA
GATCAAGGATATTCAAGAAGACCTGAAACACAAGCAGGGTGACAGTGCCATGATAAAGGAAGAAGTTACCGCTGAGGACA
TTGCCGATGTTGTTTCACGGTGGACAGGGATACCGGTCAACAAGATGCTGCAAAGCGAACGTGACAAATTGCTTCATCTG
GAGCAAGAATTACATTTGCGTGTGGTAGGTCAGGATGAAGCCATAGCAGCCGTATCCGATGCCGTACGCCGTAGCCGTGC
CGGATTACAGGACCCGAAACGTCCGATAGGTTCATTCATCTTCCTGGGTACTACCGGTGTAGGTAAGACAGAACTTGCCA
AAGCATTGGCCGACTACCTGTTTGATGACGAGAGTCTGATGACGCGTATCGACATGAGCGAATATCAGGAGAAACACTCT
GTATCCCGTCTGATCGGAGCGCCTCCCGGATACGTAGGTTACGATGAAGGCGGTCAGTTGACAGAAGCCGTCCGACGCAA
ACCATACTCTGTGGTATTGTTTGATGAAATAGAAAAAGCACATCCCGATGTGTTCAATATTCTGCTGCAAGTTTTGGATG
ACGGACGTCTGACTGACAACAAGGGACGTACGGTAAACTTCAAGAATACAATTATCATCATGACTTCCAATCTGGGCAGC
GCATACATTCAAAGCCAGTTCGAAAAGATTAATGACGAGAATCGCGAAGTGGTGATTGAAGAGACGAAGAAAGAGGTAAT
GTCCATGTTGAAAAAAACGATACGGCCGGAGTTTCTGAACCGTATAGATGAAACAATCATGTTCTTGCCTTTGAACAGAG
AAGAGATAGAACAGATTGTGATGTTACAAATCAACGGTATCAAGAATATGCTGGCCGGCAACGGCATTACTTTGGAAATG
ACCGATGAGGCCGTCCGTTTCATTGCCAGCACAGGCTATGATCCCGAATTCGGTGCCCGTCCCGTGAAACGTGCCATCCA
ACGCTATTTGCTGAATGATTTGTCCAAAAAGCTATTGTCACAGGAAGTGGACCGAAGCAAACCGATTATCGTAGAAACAG
CGGGTGACGGATTAAAATTCCGCAACTAG

Upstream 100 bases:

>100_bases
TTTGACGATTATCAAATGAAATCGCAAAAGCCACTGAACAAAGCAGTGACAGTTACGTTTTCAATAGGTATTTGAATAAT
ATTTAGAAAGGAGATACAAT

Downstream 100 bases:

>100_bases
AATGTTACAAACAACCAGTAAAGATAAGGTCTTATCTTTACTAAGCAAAAGGGGTGTTCATCATGCACCCCTTTTTTCGT
TAACTATAGCCCTCTATCTG

Product: endopeptidase Clp ATP-binding chain B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 862; Mature: 862

Protein sequence:

>862_residues
MNFNNFTIKSQEAVQQAVNITQARGQQAIEPVHLLAGVLKVGENVTNFIFQKLGMNAQQIALVIDKQIDSLPKVSGGEPY
LSRESNEILQRAVQYSKEMGDEFVSLEAIILALLNVKSTVATILKDAGMTDKELRSAIAELRKGEKVTSQSSEDTYQSLS
KYAINLNEAARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRIIRGDVPDNLKNKQIFSLDM
GALVAGAKYKGEFEERLKSVVNEVIKAEGSIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVMVAEPDTLSTISILRGLKERYENHHKVRIKDEAIIAAVELSNRYITERFLPDKAIDLMDEAAAKLR
MERDSVPEELDEISRHLKQLEIEREAIKREKDEPKLQQLNKEIAELKEQETSYKAKWQSEKELVNKIQQNKQEIEQLKFE
AEKAEREGDYGKVAEIRYGKLQALENEIKDIQEDLKHKQGDSAMIKEEVTAEDIADVVSRWTGIPVNKMLQSERDKLLHL
EQELHLRVVGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALADYLFDDESLMTRIDMSEYQEKHS
VSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
AYIQSQFEKINDENREVVIEETKKEVMSMLKKTIRPEFLNRIDETIMFLPLNREEIEQIVMLQINGIKNMLAGNGITLEM
TDEAVRFIASTGYDPEFGARPVKRAIQRYLLNDLSKKLLSQEVDRSKPIIVETAGDGLKFRN

Sequences:

>Translated_862_residues
MNFNNFTIKSQEAVQQAVNITQARGQQAIEPVHLLAGVLKVGENVTNFIFQKLGMNAQQIALVIDKQIDSLPKVSGGEPY
LSRESNEILQRAVQYSKEMGDEFVSLEAIILALLNVKSTVATILKDAGMTDKELRSAIAELRKGEKVTSQSSEDTYQSLS
KYAINLNEAARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRIIRGDVPDNLKNKQIFSLDM
GALVAGAKYKGEFEERLKSVVNEVIKAEGSIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVMVAEPDTLSTISILRGLKERYENHHKVRIKDEAIIAAVELSNRYITERFLPDKAIDLMDEAAAKLR
MERDSVPEELDEISRHLKQLEIEREAIKREKDEPKLQQLNKEIAELKEQETSYKAKWQSEKELVNKIQQNKQEIEQLKFE
AEKAEREGDYGKVAEIRYGKLQALENEIKDIQEDLKHKQGDSAMIKEEVTAEDIADVVSRWTGIPVNKMLQSERDKLLHL
EQELHLRVVGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALADYLFDDESLMTRIDMSEYQEKHS
VSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
AYIQSQFEKINDENREVVIEETKKEVMSMLKKTIRPEFLNRIDETIMFLPLNREEIEQIVMLQINGIKNMLAGNGITLEM
TDEAVRFIASTGYDPEFGARPVKRAIQRYLLNDLSKKLLSQEVDRSKPIIVETAGDGLKFRN
>Mature_862_residues
MNFNNFTIKSQEAVQQAVNITQARGQQAIEPVHLLAGVLKVGENVTNFIFQKLGMNAQQIALVIDKQIDSLPKVSGGEPY
LSRESNEILQRAVQYSKEMGDEFVSLEAIILALLNVKSTVATILKDAGMTDKELRSAIAELRKGEKVTSQSSEDTYQSLS
KYAINLNEAARSGKLDPVIGRDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRIIRGDVPDNLKNKQIFSLDM
GALVAGAKYKGEFEERLKSVVNEVIKAEGSIILFIDEIHTLVGAGKGEGAMDAANILKPALARGELRSIGATTLDEYQKY
FEKDKALERRFQTVMVAEPDTLSTISILRGLKERYENHHKVRIKDEAIIAAVELSNRYITERFLPDKAIDLMDEAAAKLR
MERDSVPEELDEISRHLKQLEIEREAIKREKDEPKLQQLNKEIAELKEQETSYKAKWQSEKELVNKIQQNKQEIEQLKFE
AEKAEREGDYGKVAEIRYGKLQALENEIKDIQEDLKHKQGDSAMIKEEVTAEDIADVVSRWTGIPVNKMLQSERDKLLHL
EQELHLRVVGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFIFLGTTGVGKTELAKALADYLFDDESLMTRIDMSEYQEKHS
VSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
AYIQSQFEKINDENREVVIEETKKEVMSMLKKTIRPEFLNRIDETIMFLPLNREEIEQIVMLQINGIKNMLAGNGITLEM
TDEAVRFIASTGYDPEFGARPVKRAIQRYLLNDLSKKLLSQEVDRSKPIIVETAGDGLKFRN

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=41.8060200668896, Blast_Score=222, Evalue=9e-58,
Organism=Escherichia coli, GI1788943, Length=862, Percent_Identity=53.1322505800464, Blast_Score=920, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=338, Percent_Identity=43.7869822485207, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=691, Percent_Identity=53.5455861070912, Blast_Score=731, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=833, Percent_Identity=43.0972388955582, Blast_Score=665, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 97159; Mature: 97159

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNNFTIKSQEAVQQAVNITQARGQQAIEPVHLLAGVLKVGENVTNFIFQKLGMNAQQI
CCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
ALVIDKQIDSLPKVSGGEPYLSRESNEILQRAVQYSKEMGDEFVSLEAIILALLNVKSTV
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATILKDAGMTDKELRSAIAELRKGEKVTSQSSEDTYQSLSKYAINLNEAARSGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCC
RDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRIIRGDVPDNLKNKQIFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
GALVAGAKYKGEFEERLKSVVNEVIKAEGSIILFIDEIHTLVGAGKGEGAMDAANILKPA
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRSIGATTLDEYQKYFEKDKALERRFQTVMVAEPDTLSTISILRGLKERYENHHK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCE
VRIKDEAIIAAVELSNRYITERFLPDKAIDLMDEAAAKLRMERDSVPEELDEISRHLKQL
EEEECCCEEEEEHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EIEREAIKREKDEPKLQQLNKEIAELKEQETSYKAKWQSEKELVNKIQQNKQEIEQLKFE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AEKAEREGDYGKVAEIRYGKLQALENEIKDIQEDLKHKQGDSAMIKEEVTAEDIADVVSR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHH
WTGIPVNKMLQSERDKLLHLEQELHLRVVGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFI
HCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHCCEE
FLGTTGVGKTELAKALADYLFDDESLMTRIDMSEYQEKHSVSRLIGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCH
AYIQSQFEKINDENREVVIEETKKEVMSMLKKTIRPEFLNRIDETIMFLPLNREEIEQIV
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCHHHHHHHH
MLQINGIKNMLAGNGITLEMTDEAVRFIASTGYDPEFGARPVKRAIQRYLLNDLSKKLLS
HHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QEVDRSKPIIVETAGDGLKFRN
HHHCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MNFNNFTIKSQEAVQQAVNITQARGQQAIEPVHLLAGVLKVGENVTNFIFQKLGMNAQQI
CCCCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
ALVIDKQIDSLPKVSGGEPYLSRESNEILQRAVQYSKEMGDEFVSLEAIILALLNVKSTV
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATILKDAGMTDKELRSAIAELRKGEKVTSQSSEDTYQSLSKYAINLNEAARSGKLDPVIG
HHHHHHCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCC
RDEEIRRVLQILSRRTKNNPILIGEPGTGKTAIVEGLAHRIIRGDVPDNLKNKQIFSLDM
CCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECH
GALVAGAKYKGEFEERLKSVVNEVIKAEGSIILFIDEIHTLVGAGKGEGAMDAANILKPA
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHH
LARGELRSIGATTLDEYQKYFEKDKALERRFQTVMVAEPDTLSTISILRGLKERYENHHK
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHCCCCE
VRIKDEAIIAAVELSNRYITERFLPDKAIDLMDEAAAKLRMERDSVPEELDEISRHLKQL
EEEECCCEEEEEHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
EIEREAIKREKDEPKLQQLNKEIAELKEQETSYKAKWQSEKELVNKIQQNKQEIEQLKFE
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AEKAEREGDYGKVAEIRYGKLQALENEIKDIQEDLKHKQGDSAMIKEEVTAEDIADVVSR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHH
WTGIPVNKMLQSERDKLLHLEQELHLRVVGQDEAIAAVSDAVRRSRAGLQDPKRPIGSFI
HCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHCCEE
FLGTTGVGKTELAKALADYLFDDESLMTRIDMSEYQEKHSVSRLIGAPPGYVGYDEGGQL
EEECCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
TEAVRRKPYSVVLFDEIEKAHPDVFNILLQVLDDGRLTDNKGRTVNFKNTIIIMTSNLGS
HHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCH
AYIQSQFEKINDENREVVIEETKKEVMSMLKKTIRPEFLNRIDETIMFLPLNREEIEQIV
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEEEECCHHHHHHHH
MLQINGIKNMLAGNGITLEMTDEAVRFIASTGYDPEFGARPVKRAIQRYLLNDLSKKLLS
HHHHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QEVDRSKPIIVETAGDGLKFRN
HHHCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]