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The map label for this gene is pepQ [H]

Identifier: 150006080

GI number: 150006080

Start: 4452779

End: 4453939

Strand: Reverse

Name: pepQ [H]

Synonym: BVU_3589

Alternate gene names: 150006080

Gene position: 4453939-4452779 (Counterclockwise)

Preceding gene: 150006086

Following gene: 150006076

Centisome position: 86.26

GC content: 44.96

Gene sequence:

>1161_bases
ATGTTACAACCCGAATTGAAATTTCGTCGAGATAAAATACGCTATTTGATGGCTCAACAAGGCATTGATGCTGCCCTGAT
AGCTTGTAATGTAAATTTGCTTTATACGTATGGTGAGATAGTGAACGGCTATCTTTATTTACCGCTTCATTCACCGGCAC
TTCTCTTTGTAAAACGTCCTAATAATATTGTGGGAGAATTTGTATTCCCTATTCGTAAACCTGAGCAGATAGTGGACTTG
TTAAAAGAAAATGGTATACCTGTAGCTTCAAAGATAATGTTGGAAGGCGGGGAACTGCCTTATGCGGACTATATGCGTCT
TGCATCTCTTTTTCCTGAATCGGAGGTCGTGGATGGAACTGCTATTATTCGTGAAGCGCGTAGTGTAAAGACTCCGCTGG
AGATTGAACTTTTTCGTCGGTCGGCTGCTTTACATGCTCGAGCATATAGTAAGATTCCCGATGTATACCATCCGGGGATG
ACTGATCGTGAACTATCTGTTGAGGTGGAACGCCTGATGCGACTGGAAGGTTGTCTGGGAATATTCAGAGTATTTGGTCA
GAGTATGGAGATATTTATGGGAAGTGTGTTGGCCGGAGATAATGCAGCTACTCCTTCGCCTTATGATTTTGCCTTAGGTG
GTAAGGGATTGGATCCGTCTTTGCCCGGAGGAATGAATGGAACTTTGTTGAAAGAGGGGTATAGTGTAATGGTGGATATA
GGGGGAAACTTTTACGGATATATGTGCGATATGAGTCGTGTGTTCTCCATTGGAAAATTAAATGATGAGGCTTATGCAGC
TCATCAAGTCTGTCTTGAAGTGCAGGATAAGGTTGCCTCTATGACGGCGCCTGGTGTGGTGTGCGAGGATCTTTATAATG
CGGCCATTGAGATCGTGACGAAAGCCGGATTTGCCGATCGTTTTATGGGGGTGTCCCAACAGGCACGTTTTATAGGACAC
GGCATCGGGTTGGAAATCAATGAGGCACCAGTGTTGGCTCCGCGTATCCGGAGGGAGTTGGAAGAGGGAATGGTGTTTGC
CCTTGAACCTAAAATCGTATTGCCGGGAGTAGGACCGGTCGGCATTGAAAATTCTTGGGTAGTTACAGAAAACGGAGCCG
GCAAACTGACCATTTGTAATGAGGAGATTATAGAGCTTTGA

Upstream 100 bases:

>100_bases
TTAATATATCCTTTCTCTTTTTTGGAACTACTATCCTTTATACTGACTGAAATCTGTTATTTTTGTACTCAGTATTTTAA
ATAATCAGATAATATTACTT

Downstream 100 bases:

>100_bases
TTCCTTGGATGTAAATATTGAAGCGGAAATATCAAAAAAACGAAAAATTTTATGGTTCTTGTTCTAGTGTCATTGGGGGC
AAAGTGAAGAACTTGAATAT

Product: putative Xaa-Pro dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MLQPELKFRRDKIRYLMAQQGIDAALIACNVNLLYTYGEIVNGYLYLPLHSPALLFVKRPNNIVGEFVFPIRKPEQIVDL
LKENGIPVASKIMLEGGELPYADYMRLASLFPESEVVDGTAIIREARSVKTPLEIELFRRSAALHARAYSKIPDVYHPGM
TDRELSVEVERLMRLEGCLGIFRVFGQSMEIFMGSVLAGDNAATPSPYDFALGGKGLDPSLPGGMNGTLLKEGYSVMVDI
GGNFYGYMCDMSRVFSIGKLNDEAYAAHQVCLEVQDKVASMTAPGVVCEDLYNAAIEIVTKAGFADRFMGVSQQARFIGH
GIGLEINEAPVLAPRIRRELEEGMVFALEPKIVLPGVGPVGIENSWVVTENGAGKLTICNEEIIEL

Sequences:

>Translated_386_residues
MLQPELKFRRDKIRYLMAQQGIDAALIACNVNLLYTYGEIVNGYLYLPLHSPALLFVKRPNNIVGEFVFPIRKPEQIVDL
LKENGIPVASKIMLEGGELPYADYMRLASLFPESEVVDGTAIIREARSVKTPLEIELFRRSAALHARAYSKIPDVYHPGM
TDRELSVEVERLMRLEGCLGIFRVFGQSMEIFMGSVLAGDNAATPSPYDFALGGKGLDPSLPGGMNGTLLKEGYSVMVDI
GGNFYGYMCDMSRVFSIGKLNDEAYAAHQVCLEVQDKVASMTAPGVVCEDLYNAAIEIVTKAGFADRFMGVSQQARFIGH
GIGLEINEAPVLAPRIRRELEEGMVFALEPKIVLPGVGPVGIENSWVVTENGAGKLTICNEEIIEL
>Mature_386_residues
MLQPELKFRRDKIRYLMAQQGIDAALIACNVNLLYTYGEIVNGYLYLPLHSPALLFVKRPNNIVGEFVFPIRKPEQIVDL
LKENGIPVASKIMLEGGELPYADYMRLASLFPESEVVDGTAIIREARSVKTPLEIELFRRSAALHARAYSKIPDVYHPGM
TDRELSVEVERLMRLEGCLGIFRVFGQSMEIFMGSVLAGDNAATPSPYDFALGGKGLDPSLPGGMNGTLLKEGYSVMVDI
GGNFYGYMCDMSRVFSIGKLNDEAYAAHQVCLEVQDKVASMTAPGVVCEDLYNAAIEIVTKAGFADRFMGVSQQARFIGH
GIGLEINEAPVLAPRIRRELEEGMVFALEPKIVLPGVGPVGIENSWVVTENGAGKLTICNEEIIEL

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=257, Percent_Identity=30.3501945525292, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 42417; Mature: 42417

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQPELKFRRDKIRYLMAQQGIDAALIACNVNLLYTYGEIVNGYLYLPLHSPALLFVKRP
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEHHHHCCEEEEEECCCEEEEEECC
NNIVGEFVFPIRKPEQIVDLLKENGIPVASKIMLEGGELPYADYMRLASLFPESEVVDGT
CCCCCHHCCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCHHHHHHHHHHCCCCCCCCHH
AIIREARSVKTPLEIELFRRSAALHARAYSKIPDVYHPGMTDRELSVEVERLMRLEGCLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IFRVFGQSMEIFMGSVLAGDNAATPSPYDFALGGKGLDPSLPGGMNGTLLKEGYSVMVDI
HHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCEEEEEE
GGNFYGYMCDMSRVFSIGKLNDEAYAAHQVCLEVQDKVASMTAPGVVCEDLYNAAIEIVT
CCCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KAGFADRFMGVSQQARFIGHGIGLEINEAPVLAPRIRRELEEGMVFALEPKIVLPGVGPV
HCCHHHHHHCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCEEEECCCEEECCCCCC
GIENSWVVTENGAGKLTICNEEIIEL
CCCCCEEEEECCCCEEEECCHHHHCC
>Mature Secondary Structure
MLQPELKFRRDKIRYLMAQQGIDAALIACNVNLLYTYGEIVNGYLYLPLHSPALLFVKRP
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEHHHHCCEEEEEECCCEEEEEECC
NNIVGEFVFPIRKPEQIVDLLKENGIPVASKIMLEGGELPYADYMRLASLFPESEVVDGT
CCCCCHHCCCCCCHHHHHHHHHHCCCCEEHEEEECCCCCCHHHHHHHHHHCCCCCCCCHH
AIIREARSVKTPLEIELFRRSAALHARAYSKIPDVYHPGMTDRELSVEVERLMRLEGCLG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IFRVFGQSMEIFMGSVLAGDNAATPSPYDFALGGKGLDPSLPGGMNGTLLKEGYSVMVDI
HHHHHCCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEECCCEEEEEE
GGNFYGYMCDMSRVFSIGKLNDEAYAAHQVCLEVQDKVASMTAPGVVCEDLYNAAIEIVT
CCCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KAGFADRFMGVSQQARFIGHGIGLEINEAPVLAPRIRRELEEGMVFALEPKIVLPGVGPV
HCCHHHHHHCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCEEEECCCEEECCCCCC
GIENSWVVTENGAGKLTICNEEIIEL
CCCCCEEEEECCCCEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]