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The map label for this gene is atpA [H]

Identifier: 150006061

GI number: 150006061

Start: 4423483

End: 4425237

Strand: Reverse

Name: atpA [H]

Synonym: BVU_3565

Alternate gene names: 150006061

Gene position: 4425237-4423483 (Counterclockwise)

Preceding gene: 150006062

Following gene: 150006060

Centisome position: 85.71

GC content: 43.93

Gene sequence:

>1755_bases
ATGGCAACAAAAGGAACTGTTAGTGGCGTAATAGCCAACATGGTTACTCTTACCGTTGACGGACCGGTGGCACAGAATGA
GATTTGTTACATTCTGACTGGCGGAGACCGCTTGATGGCAGAGGTTATTAAGGTGGTAGGCAGCAATGTTTATGTGCAGG
TGTTTGAAAGTACACGTGGATTGAAAGTTGGTGCTGAAGCCGAATTTACGGGACACATGCTTGAAGTGACTCTAGGTCCG
GGTATGTTGTCTAAAAATTATGATGGTCTGCAAAACGACCTTGATAAAATGGATGGAGTGTTCCTGAAACGCGGACAATA
CACCTATCCATTGGATAAAGAAAGAGTGTGGCATTTTGTACCGTTGGTGAACGTGGGTGATGAAGTTGGTCCATCGGCTT
GGTTGGGACAGGTGGATGAGAACTTCCAGCCACTGAAAATTATGGTACCATTTCAGTTGACAGGTACTTATAAAGTGAAA
TCCATTGTTCCTGAAGGTGATTATACTATTGAGGATACTGTAGTGGTTCTGACGGACAGAGAAGGTAAAGATATTCCGGT
AAACATGATTCAGAAGTGGCCGGTAAAGAAGGCTATGACTAATTATAAGGAAAAGCCGCGTCCTTATAAATTATTGGAAA
CCGGTGTCCGTGTTATTGATACGGTCAACCCCATTGTAGAAGGGGGAACGGGATTTATTCCCGGTCCGTTTGGTACAGGG
AAAACAGTGCTTCAGCATGCCATCTCCAAGCAGGCGGAAGCGGATATCGTAATTATCGCTGCTTGTGGTGAACGTGCGAA
TGAGGTGGTGGAAATCTTTACGGAGTTCCCCGAACTGGTAGATCCGCATACAGGACGTAAGCTGATGGAACGTACTATCA
TTATTGCCAATACCTCGAACATGCCGGTGGCTGCCCGTGAAGCGTCTGTGTACACGGCTATGACCATTTCTGAGTATTAT
CGTGCTATGGGATTGAAAGTCTTACTGATGGCAGATTCTACTTCCCGTTGGGCGCAGGCCTTGCGTGAGATGTCCAACCG
TATGGAAGAATTGCCTGGTCCGGATGCATTCCCGATGGATATCTCGGCTATTATCTCCAACTTTTACGGACGTGCGGGAT
ATGTACATCTGAATAATGGTGAGACCGGTTCTATTACCTTTATCGGTACTGTATCTCCGGCAGGTGGTAACTTGAAGGAA
CCTGTAACGGAGAATACTAAAAAGGTGGCCCGTTGCTTTTATGCCTTGGAGCAGGAACGTGCCGACAGGAAGCGTTATCC
GGCTGTGAACCCGATTGACTCTTATTCAAAATATCTGGAATATCCGGAATTTGAGGAATATATCGCCAAACGTATTAATG
GTGAATGGATTGGTAAGGTGAACGAAATCAAAACAAGATTGTTGCGTGGTAAGGAAATTGCTGAACAGATTAATATTTTG
GGTGATGATGGCGTACCTGTAGAATATCATGTAATCTTTTGGAAATCAGAGTTGATTGATTTTGTGATTCTGCAACAGGA
TGCTTTTGATGAAGTGGATTCAGTGACTCCGATGGAACGTCAGGAGGAGATCTTGAATATGGTAATCGACATCTGTCATA
CGGAATTCAAGTTTGATACTTTCATTGAGGTGATGGATTATTTCAAAAAGATGATCAACCTTTGCAAACAGATGAACTAT
GCTAAATATAAATCTGAGCAGTATGAGGATTTTAAGAAGCAGTTACAGGAATTGGTTGCCGAGAGAAGTGTCTGA

Upstream 100 bases:

>100_bases
TAAGGAAAAGGGAAGCGAACTGTTCCGTCAGATTATTGATAAATTAAAGGACGAGATACAGATTCCCGCAGAATTCAGAT
AATAAACAGATTAAAGATAT

Downstream 100 bases:

>100_bases
TTTTAATTTTTAATTTTAATTTATAATGAGTAGAGATGGCAACAAAAGCATTTCAAAAGATATATACTAAGATTAGCCAG
ATTACCAAGGCAACCTGTTC

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MATKGTVSGVIANMVTLTVDGPVAQNEICYILTGGDRLMAEVIKVVGSNVYVQVFESTRGLKVGAEAEFTGHMLEVTLGP
GMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERVWHFVPLVNVGDEVGPSAWLGQVDENFQPLKIMVPFQLTGTYKVK
SIVPEGDYTIEDTVVVLTDREGKDIPVNMIQKWPVKKAMTNYKEKPRPYKLLETGVRVIDTVNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTISEYY
RAMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVHLNNGETGSITFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQERADRKRYPAVNPIDSYSKYLEYPEFEEYIAKRINGEWIGKVNEIKTRLLRGKEIAEQINIL
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEEILNMVIDICHTEFKFDTFIEVMDYFKKMINLCKQMNY
AKYKSEQYEDFKKQLQELVAERSV

Sequences:

>Translated_584_residues
MATKGTVSGVIANMVTLTVDGPVAQNEICYILTGGDRLMAEVIKVVGSNVYVQVFESTRGLKVGAEAEFTGHMLEVTLGP
GMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERVWHFVPLVNVGDEVGPSAWLGQVDENFQPLKIMVPFQLTGTYKVK
SIVPEGDYTIEDTVVVLTDREGKDIPVNMIQKWPVKKAMTNYKEKPRPYKLLETGVRVIDTVNPIVEGGTGFIPGPFGTG
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTISEYY
RAMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVHLNNGETGSITFIGTVSPAGGNLKE
PVTENTKKVARCFYALEQERADRKRYPAVNPIDSYSKYLEYPEFEEYIAKRINGEWIGKVNEIKTRLLRGKEIAEQINIL
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEEILNMVIDICHTEFKFDTFIEVMDYFKKMINLCKQMNY
AKYKSEQYEDFKKQLQELVAERSV
>Mature_583_residues
ATKGTVSGVIANMVTLTVDGPVAQNEICYILTGGDRLMAEVIKVVGSNVYVQVFESTRGLKVGAEAEFTGHMLEVTLGPG
MLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERVWHFVPLVNVGDEVGPSAWLGQVDENFQPLKIMVPFQLTGTYKVKS
IVPEGDYTIEDTVVVLTDREGKDIPVNMIQKWPVKKAMTNYKEKPRPYKLLETGVRVIDTVNPIVEGGTGFIPGPFGTGK
TVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSNMPVAAREASVYTAMTISEYYR
AMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMDISAIISNFYGRAGYVHLNNGETGSITFIGTVSPAGGNLKEP
VTENTKKVARCFYALEQERADRKRYPAVNPIDSYSKYLEYPEFEEYIAKRINGEWIGKVNEIKTRLLRGKEIAEQINILG
DDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEEILNMVIDICHTEFKFDTFIEVMDYFKKMINLCKQMNYA
KYKSEQYEDFKKQLQELVAERSV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=539, Percent_Identity=37.6623376623377, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI32189394, Length=286, Percent_Identity=24.4755244755245, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI19913428, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790170, Length=364, Percent_Identity=25.2747252747253, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788251, Length=265, Percent_Identity=26.0377358490566, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790172, Length=275, Percent_Identity=26.5454545454545, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565854, Length=546, Percent_Identity=36.996336996337, Blast_Score=324, Evalue=8e-89,
Organism=Caenorhabditis elegans, GI25144756, Length=237, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17510931, Length=244, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570191, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320016, Length=289, Percent_Identity=37.0242214532872, Blast_Score=195, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322581, Length=362, Percent_Identity=24.8618784530387, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319603, Length=319, Percent_Identity=23.8244514106583, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=229, Percent_Identity=24.0174672489083, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583992, Length=533, Percent_Identity=36.7729831144465, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24583988, Length=533, Percent_Identity=36.5853658536585, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24583986, Length=533, Percent_Identity=36.5853658536585, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24583984, Length=533, Percent_Identity=36.5853658536585, Blast_Score=324, Evalue=1e-88,
Organism=Drosophila melanogaster, GI20129479, Length=534, Percent_Identity=35.0187265917603, Blast_Score=308, Evalue=5e-84,
Organism=Drosophila melanogaster, GI28574560, Length=252, Percent_Identity=29.3650793650794, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24638766, Length=287, Percent_Identity=23.6933797909408, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281361666, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24646341, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17136796, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65768; Mature: 65637

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATKGTVSGVIANMVTLTVDGPVAQNEICYILTGGDRLMAEVIKVVGSNVYVQVFESTRG
CCCCCHHHHHHHEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCC
LKVGAEAEFTGHMLEVTLGPGMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERVWHFV
EEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHEEEE
PLVNVGDEVGPSAWLGQVDENFQPLKIMVPFQLTGTYKVKSIVPEGDYTIEDTVVVLTDR
EEECCCCCCCCHHHHCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEECCEEEEEECC
EGKDIPVNMIQKWPVKKAMTNYKEKPRPYKLLETGVRVIDTVNPIVEGGTGFIPGPFGTG
CCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMTISEYYRAMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMD
CCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ISAIISNFYGRAGYVHLNNGETGSITFIGTVSPAGGNLKEPVTENTKKVARCFYALEQER
HHHHHHHHCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADRKRYPAVNPIDSYSKYLEYPEFEEYIAKRINGEWIGKVNEIKTRLLRGKEIAEQINIL
HHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCC
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEEILNMVIDICHTEFKFDT
CCCCCCEEEEEEEEHHHHHHHHEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHH
FIEVMDYFKKMINLCKQMNYAKYKSEQYEDFKKQLQELVAERSV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATKGTVSGVIANMVTLTVDGPVAQNEICYILTGGDRLMAEVIKVVGSNVYVQVFESTRG
CCCCHHHHHHHEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEEECCCC
LKVGAEAEFTGHMLEVTLGPGMLSKNYDGLQNDLDKMDGVFLKRGQYTYPLDKERVWHFV
EEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCEEEECCCCCCCCCHHHHEEEE
PLVNVGDEVGPSAWLGQVDENFQPLKIMVPFQLTGTYKVKSIVPEGDYTIEDTVVVLTDR
EEECCCCCCCCHHHHCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEECCEEEEEECC
EGKDIPVNMIQKWPVKKAMTNYKEKPRPYKLLETGVRVIDTVNPIVEGGTGFIPGPFGTG
CCCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
KTVLQHAISKQAEADIVIIAACGERANEVVEIFTEFPELVDPHTGRKLMERTIIIANTSN
HHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCEEEEEECCC
MPVAAREASVYTAMTISEYYRAMGLKVLLMADSTSRWAQALREMSNRMEELPGPDAFPMD
CCEEECCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
ISAIISNFYGRAGYVHLNNGETGSITFIGTVSPAGGNLKEPVTENTKKVARCFYALEQER
HHHHHHHHCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADRKRYPAVNPIDSYSKYLEYPEFEEYIAKRINGEWIGKVNEIKTRLLRGKEIAEQINIL
HHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCC
GDDGVPVEYHVIFWKSELIDFVILQQDAFDEVDSVTPMERQEEILNMVIDICHTEFKFDT
CCCCCCEEEEEEEEHHHHHHHHEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHH
FIEVMDYFKKMINLCKQMNYAKYKSEQYEDFKKQLQELVAERSV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA