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The map label for this gene is macA [H]

Identifier: 150006027

GI number: 150006027

Start: 4380352

End: 4381602

Strand: Reverse

Name: macA [H]

Synonym: BVU_3525

Alternate gene names: 150006027

Gene position: 4381602-4380352 (Counterclockwise)

Preceding gene: 150006028

Following gene: 150006026

Centisome position: 84.86

GC content: 43.57

Gene sequence:

>1251_bases
ATGGACACACTAATTGAACGTAAAAAGCGTTTCACTCCCAGGCGGATTTATGGAGGTGCGGGAGTATTATTCATATTGGT
ATTCGTTTTTTATTTTATTTTTCGTGATACCGGTTCCTCCATGACCATTGACAAGAGCCGTATCACTATCGCTACAGTTA
CAGAAAATGAGTTTAATGATTATGTCCGTGTGATTGGACAAGTACTTCCCAGCCGCATGATTTACCTCGATGCTATAGAA
GGCGGAAGAGTGGAGGAACGCCTTCATGAAGAGGGAGCGATGGTAAAGAAAGGGGATGTGATTCTGCGCCTGAGTAATCC
TCTGCTGAATATCGGTATCATGCAAAGTGAAGCAGATCTGGCTTATCAGGAAAACGAGTTGCGTAATACTCGTATAAGTA
TGGAGCAGGAACGGTTGAGTCTGAAGCAGGATCGTATCGGTATTCAGAAAGAATTCATTATAAAGAAACGTCGTTACGGA
CAATACAAGCGGCTGATGGAGGGGCAATTGATAGCGAGGGAGGACTATCTCCAAGCTACGGAGGAATATGAAGCGGTAAA
AGAACAATTGTCGGTATTGGATGAGCGGATCCGTCAAGATAGTTTGTTTCGTTTGACTCAGATAAGCAGTTTGGACGAGA
ATATAATGAATATGAAACGAAGTTTGGCATTGGTACGAGAACGTCTTGAAAACCTGAAAGTGAAAGCTCCTATAGACGGG
CAAGTGGGTAATCTTGAAGCACAAATCGGGCAATCCATTTCTGCCGGGGAACATATCGGTCAGATTATTACTGCTGATCT
GAAGGTACAGGCATTAATTGATGAGCATTATGTGGAGCGTGTCGTCCAAGAGCTTCCCGCTGACTTTACCCGTGATGGAG
AAAATTATAAGTTGGAAGTAACCAAAGTGTATCCTGAAGTGAAAGACGGGCAGTTTCGTACAGATTTCCGTTTCACGACA
GGGCGTCCCGAAAACATTCGGGCGGGACAAACTTATCATATCAATCTTCAGTTGGGGGATCCTGTCAAAGCTGTTCTGAT
TCCTCGGGGAGGTTTTTTTCAAATTACCGGAGGACGATGGATATATGTTGTGGATGAAAGTGGTAAATTTGCCGTCAGAC
GTCCTATCAAGATTGGCAGGCAGAATCCTCAGTTTTATGAAGTGACTGACGGGCTGGCTTCCGGTGAGAAAGTTATTATT
TCCGGTTACGAGCTGTTTGGAGATAATGAGAAACTGATTTTAAACGAATAA

Upstream 100 bases:

>100_bases
TCGCTAAAGCGGAAAAAATAAGAGTGCGTTTGCAGTACGAACTGACATCGCGACTAACTATGTATTATCGGACAGGAAGT
TTTATTAACCATTAAAAAAT

Downstream 100 bases:

>100_bases
AAAACACGTAAGAATGATTAAAGTAGAAAACCTCTCTATGTTGTTCAGCACCGAGGAAGTGCAGACCAAAGCATTGAATG
AAGTAACTTTCGAAATTGAA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MDTLIERKKRFTPRRIYGGAGVLFILVFVFYFIFRDTGSSMTIDKSRITIATVTENEFNDYVRVIGQVLPSRMIYLDAIE
GGRVEERLHEEGAMVKKGDVILRLSNPLLNIGIMQSEADLAYQENELRNTRISMEQERLSLKQDRIGIQKEFIIKKRRYG
QYKRLMEGQLIAREDYLQATEEYEAVKEQLSVLDERIRQDSLFRLTQISSLDENIMNMKRSLALVRERLENLKVKAPIDG
QVGNLEAQIGQSISAGEHIGQIITADLKVQALIDEHYVERVVQELPADFTRDGENYKLEVTKVYPEVKDGQFRTDFRFTT
GRPENIRAGQTYHINLQLGDPVKAVLIPRGGFFQITGGRWIYVVDESGKFAVRRPIKIGRQNPQFYEVTDGLASGEKVII
SGYELFGDNEKLILNE

Sequences:

>Translated_416_residues
MDTLIERKKRFTPRRIYGGAGVLFILVFVFYFIFRDTGSSMTIDKSRITIATVTENEFNDYVRVIGQVLPSRMIYLDAIE
GGRVEERLHEEGAMVKKGDVILRLSNPLLNIGIMQSEADLAYQENELRNTRISMEQERLSLKQDRIGIQKEFIIKKRRYG
QYKRLMEGQLIAREDYLQATEEYEAVKEQLSVLDERIRQDSLFRLTQISSLDENIMNMKRSLALVRERLENLKVKAPIDG
QVGNLEAQIGQSISAGEHIGQIITADLKVQALIDEHYVERVVQELPADFTRDGENYKLEVTKVYPEVKDGQFRTDFRFTT
GRPENIRAGQTYHINLQLGDPVKAVLIPRGGFFQITGGRWIYVVDESGKFAVRRPIKIGRQNPQFYEVTDGLASGEKVII
SGYELFGDNEKLILNE
>Mature_416_residues
MDTLIERKKRFTPRRIYGGAGVLFILVFVFYFIFRDTGSSMTIDKSRITIATVTENEFNDYVRVIGQVLPSRMIYLDAIE
GGRVEERLHEEGAMVKKGDVILRLSNPLLNIGIMQSEADLAYQENELRNTRISMEQERLSLKQDRIGIQKEFIIKKRRYG
QYKRLMEGQLIAREDYLQATEEYEAVKEQLSVLDERIRQDSLFRLTQISSLDENIMNMKRSLALVRERLENLKVKAPIDG
QVGNLEAQIGQSISAGEHIGQIITADLKVQALIDEHYVERVVQELPADFTRDGENYKLEVTKVYPEVKDGQFRTDFRFTT
GRPENIRAGQTYHINLQLGDPVKAVLIPRGGFFQITGGRWIYVVDESGKFAVRRPIKIGRQNPQFYEVTDGLASGEKVII
SGYELFGDNEKLILNE

Specific function: Efflux transporter for macrolide antibiotics [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47798; Mature: 47798

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLIERKKRFTPRRIYGGAGVLFILVFVFYFIFRDTGSSMTIDKSRITIATVTENEFND
CCCHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEECHHHHH
YVRVIGQVLPSRMIYLDAIEGGRVEERLHEEGAMVKKGDVILRLSNPLLNIGIMQSEADL
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEECCCEEEEECCCEEEEEEEECCCCH
AYQENELRNTRISMEQERLSLKQDRIGIQKEFIIKKRRYGQYKRLMEGQLIAREDYLQAT
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
EEYEAVKEQLSVLDERIRQDSLFRLTQISSLDENIMNMKRSLALVRERLENLKVKAPIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
QVGNLEAQIGQSISAGEHIGQIITADLKVQALIDEHYVERVVQELPADFTRDGENYKLEV
CCCCCHHHHCCCCCCHHHHHHHEEECEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
TKVYPEVKDGQFRTDFRFTTGRPENIRAGQTYHINLQLGDPVKAVLIPRGGFFQITGGRW
EEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEECCEE
IYVVDESGKFAVRRPIKIGRQNPQFYEVTDGLASGEKVIISGYELFGDNEKLILNE
EEEEECCCCEEEECCHHCCCCCCCEEEECCCCCCCCEEEEEEEEEECCCCEEEECC
>Mature Secondary Structure
MDTLIERKKRFTPRRIYGGAGVLFILVFVFYFIFRDTGSSMTIDKSRITIATVTENEFND
CCCHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEECHHHHH
YVRVIGQVLPSRMIYLDAIEGGRVEERLHEEGAMVKKGDVILRLSNPLLNIGIMQSEADL
HHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCEEECCCEEEEECCCEEEEEEEECCCCH
AYQENELRNTRISMEQERLSLKQDRIGIQKEFIIKKRRYGQYKRLMEGQLIAREDYLQAT
HHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
EEYEAVKEQLSVLDERIRQDSLFRLTQISSLDENIMNMKRSLALVRERLENLKVKAPIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCC
QVGNLEAQIGQSISAGEHIGQIITADLKVQALIDEHYVERVVQELPADFTRDGENYKLEV
CCCCCHHHHCCCCCCHHHHHHHEEECEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
TKVYPEVKDGQFRTDFRFTTGRPENIRAGQTYHINLQLGDPVKAVLIPRGGFFQITGGRW
EEECCCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEECCEE
IYVVDESGKFAVRRPIKIGRQNPQFYEVTDGLASGEKVIISGYELFGDNEKLILNE
EEEEECCCCEEEECCHHCCCCCCCEEEECCCCCCCCEEEEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]