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The map label for this gene is gpmA [H]

Identifier: 150006017

GI number: 150006017

Start: 4371773

End: 4372522

Strand: Reverse

Name: gpmA [H]

Synonym: BVU_3515

Alternate gene names: 150006017

Gene position: 4372522-4371773 (Counterclockwise)

Preceding gene: 150006018

Following gene: 150006016

Centisome position: 84.69

GC content: 48.27

Gene sequence:

>750_bases
ATGAAAAGAATAGTGTTATTACGTCATGGCGAAAGCCTATGGAACAAAGAAAACCGTTTTACTGGATGGACGGACGTGGA
TTTAAGCGAGAAAGGAGTTGAAGAAGCCTGCAAGGCAGGCGATGCATTACGGGAGGCTGGATTTTCTTTTGAGGCAGCTT
ACACTTCTTACTTGAAACGTGCCGTAAAAACGTTGAACTGTGTCTTGGACCGGCTGGATGAAGACTGGATTCCGGTTGAA
AAGACCTGGCGGCTGAACGAGAAGCATTACGGCATGCTTCAGGGACTGAATAAGAGTGAAACAGCGGTCCAATATGGTGA
AGAACAAGTACACATCTGGCGAAGAAGCTATGACGTGGCTCCCGCTCCGGTAGGCAAAGATGATCCCCGTAATCCGGGCA
TGGATATCCGCTATGCCGGTGTACCAGATAGGGAACTTCCCCGTACGGAATCCCTGAAAGATACTATTGGGCGTGTCATG
CCTTACTGGAAATGCATCATCTTTCCCGCATTGATGTATAAGGACAGCCTGCTGGTAGTCGCCCATGGTAACAGCCTGCG
CGGAATCATCAAGCATCTCAAAGGAATTTCCGATACGGATATTTCCAACCTGAACCTGCCTACGGCAGTTCCTTATGTCT
TTGAATTTGACGACAGGCTGGTTCTTGTCAAGGACTACTACCTTGGAAACCCGGAAGAGATACGGAAACGGGCAGAAGCT
GTGGCCAAACAAGGGATGGCTAAAAAATAA

Upstream 100 bases:

>100_bases
GCTTTCCAGAAACCGATGAAAGACGGAGTTCAACTTCTGAACACCATTCAGGACGTATATCTGGATTCTTCAATAACCAT
TGCATAAAGAAGAAGTATCC

Downstream 100 bases:

>100_bases
AAATCTGTCTATCAAGCAGATGCTTTTTTTTAAGTTTTAATTATTAACTTTTAAAGAGGAGGTAAAAATGGTACCTGTAA
AAACAAACCAGAATTGGTTA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKRIVLLRHGESLWNKENRFTGWTDVDLSEKGVEEACKAGDALREAGFSFEAAYTSYLKRAVKTLNCVLDRLDEDWIPVE
KTWRLNEKHYGMLQGLNKSETAVQYGEEQVHIWRRSYDVAPAPVGKDDPRNPGMDIRYAGVPDRELPRTESLKDTIGRVM
PYWKCIIFPALMYKDSLLVVAHGNSLRGIIKHLKGISDTDISNLNLPTAVPYVFEFDDRLVLVKDYYLGNPEEIRKRAEA
VAKQGMAKK

Sequences:

>Translated_249_residues
MKRIVLLRHGESLWNKENRFTGWTDVDLSEKGVEEACKAGDALREAGFSFEAAYTSYLKRAVKTLNCVLDRLDEDWIPVE
KTWRLNEKHYGMLQGLNKSETAVQYGEEQVHIWRRSYDVAPAPVGKDDPRNPGMDIRYAGVPDRELPRTESLKDTIGRVM
PYWKCIIFPALMYKDSLLVVAHGNSLRGIIKHLKGISDTDISNLNLPTAVPYVFEFDDRLVLVKDYYLGNPEEIRKRAEA
VAKQGMAKK
>Mature_249_residues
MKRIVLLRHGESLWNKENRFTGWTDVDLSEKGVEEACKAGDALREAGFSFEAAYTSYLKRAVKTLNCVLDRLDEDWIPVE
KTWRLNEKHYGMLQGLNKSETAVQYGEEQVHIWRRSYDVAPAPVGKDDPRNPGMDIRYAGVPDRELPRTESLKDTIGRVM
PYWKCIIFPALMYKDSLLVVAHGNSLRGIIKHLKGISDTDISNLNLPTAVPYVFEFDDRLVLVKDYYLGNPEEIRKRAEA
VAKQGMAKK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=249, Percent_Identity=53.0120481927711, Blast_Score=271, Evalue=3e-73,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=54.8, Blast_Score=265, Evalue=4e-71,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=52.4, Blast_Score=247, Evalue=9e-66,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=45.2380952380952, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=45.2380952380952, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=57.7639751552795, Blast_Score=181, Evalue=4e-46,
Organism=Escherichia coli, GI1786970, Length=248, Percent_Identity=58.0645161290323, Blast_Score=291, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322697, Length=245, Percent_Identity=48.5714285714286, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6320183, Length=304, Percent_Identity=32.2368421052632, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324516, Length=295, Percent_Identity=29.8305084745763, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=51.6, Blast_Score=254, Evalue=3e-68,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=51.2, Blast_Score=244, Evalue=5e-65,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=51.2, Blast_Score=244, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=51.2, Blast_Score=244, Evalue=5e-65,
Organism=Drosophila melanogaster, GI28571817, Length=252, Percent_Identity=38.8888888888889, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24648979, Length=252, Percent_Identity=38.8888888888889, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI28571815, Length=252, Percent_Identity=38.8888888888889, Blast_Score=174, Evalue=6e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28490; Mature: 28490

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00559 MOLYBDOPTERIN_EUK ; PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVLLRHGESLWNKENRFTGWTDVDLSEKGVEEACKAGDALREAGFSFEAAYTSYLKR
CCEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AVKTLNCVLDRLDEDWIPVEKTWRLNEKHYGMLQGLNKSETAVQYGEEQVHIWRRSYDVA
HHHHHHHHHHHHCCCCCCCCHHEECCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCC
PAPVGKDDPRNPGMDIRYAGVPDRELPRTESLKDTIGRVMPYWKCIIFPALMYKDSLLVV
CCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHGNSLRGIIKHLKGISDTDISNLNLPTAVPYVFEFDDRLVLVKDYYLGNPEEIRKRAEA
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHH
VAKQGMAKK
HHHCCCCCC
>Mature Secondary Structure
MKRIVLLRHGESLWNKENRFTGWTDVDLSEKGVEEACKAGDALREAGFSFEAAYTSYLKR
CCEEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AVKTLNCVLDRLDEDWIPVEKTWRLNEKHYGMLQGLNKSETAVQYGEEQVHIWRRSYDVA
HHHHHHHHHHHHCCCCCCCCHHEECCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCC
PAPVGKDDPRNPGMDIRYAGVPDRELPRTESLKDTIGRVMPYWKCIIFPALMYKDSLLVV
CCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
AHGNSLRGIIKHLKGISDTDISNLNLPTAVPYVFEFDDRLVLVKDYYLGNPEEIRKRAEA
ECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHHH
VAKQGMAKK
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]