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The map label for this gene is atoC [H]

Identifier: 150005776

GI number: 150005776

Start: 4101655

End: 4102992

Strand: Reverse

Name: atoC [H]

Synonym: BVU_3269

Alternate gene names: 150005776

Gene position: 4102992-4101655 (Counterclockwise)

Preceding gene: 150005782

Following gene: 150005774

Centisome position: 79.47

GC content: 43.5

Gene sequence:

>1338_bases
ATGGATAGTATTTTAATTATTGATGATGAACCGCAAATACGCAAACTTCTTTCGCGTATGATGGAATTGGAAGGTTACGA
AGTATTCCAGGCAGCCGATTGCCAGTCTACATTGAAACAACTTAAGTTACATAATCCCCAAGTGGTGTTGTGTGATGTGT
TTTTGCCGGACGGCAATGGAGTGGATATGGTTACAACCATCAAAAAACTCTATCCAGAATTGGAGGTGATACTTTTGACC
GCCCACGGTAACATTCCGGATGGTGTGCAGGCAATCAAGAATGGAGCCTTTGATTATATCACCAAAGGGGATGATAATAA
TAAAATTATTCCGTTAATCAGCCGGGCTATGGCTCAGGCTAAAAAGAATGTAGGAGAAAAAGTGAAAACAGAAGAGACCC
AAAGTTTCTCTTTTGACGCTATAAAAGGGAAGTCGGAGGGTATGCAACAAGCCGTAGCATTGGCCCGAAAGGTTTCGGCA
ACGGATGTTACAGTCTTGCTGACCGGAGAAACAGGCACGGGGAAAGAGGTCTTTGCACAAGCCATCCATCGCAACAGTCT
TCGCAAAGAGAATGCTTTTGTGGCTGTAAACTGTTCTGCTTTTAGCAAAGATCTGCTTGAAAGCGAGATATTCGGTCATA
AAGCCGGTTCGTTTACCGGAGCGATGAAAGATAAGAAGGGGCTGTTCGAAGTGGCCGATAACGGAACCATCTTTTTGGAT
GAAATAGGTGAAATGGCTTTCGAGCTGCAAGCCAAATTACTTCGTGTGCTCGAAGCGGGAGAGTACATCAAGATAGGCGA
CACGAAACCGACGAAAGTGAATGTCCGCGTTATCTCCGCCACCAATCGGGACCTGAAAAAAGAAATAGAACAAGGTAATT
TCCGTGAAGATCTTTATTATCGTCTTTCTGTTTTTCAGATACACCTCCCTCCTCTTCGTGAGCGCAAAGAAGACATCGAA
CTTTTGGCGGAAAGCTTTATCCAACTCTTTTCAAAGAAACTGGGGAAACAGGTGGAAGGGATGGCTCCGGAGTTCTTGAA
AGCTTTGAAAGCTGCCGACTGGAGAGGAAATATCCGTGAATTGCGAAACGTGATAGAACGCAGCATGATTGTCTGCGACA
AACAGCTCACCTTACAAGATCTTCCCATTGAAATACAGAATGCCCGGCAGGAAGATTATTCCGGCAAGAATTATTCGGAG
TTTGAACTGGCCGCTATGGAAAAACGTCATATTGCTAAAGTTCTGCAACATACTAAAGGAAACAAGACCGAGGCTTCACG
TTTATTGAAAATAGGTTTGACTACTTTATATAGAAAGATAGAGGAATACGGTATTTAG

Upstream 100 bases:

>100_bases
GCTAATCAGAAAGCGTTTTCTATAAAACAGAAATTAAGTATTATCCTTTTGTCGAGCGTTCATTTTATTCTATCTTTGTC
ACGCAAAACAGAATAAATAT

Downstream 100 bases:

>100_bases
TTGTTGCAGGTCATTGATCAACCCTTTCCTGCCCTATGGTTAAGTCTTTTTATACGGATGTATTCTATCTCCATAGCCTT
TGGAGTTAACTCCAAAGACT

Product: two-component system response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDSILIIDDEPQIRKLLSRMMELEGYEVFQAADCQSTLKQLKLHNPQVVLCDVFLPDGNGVDMVTTIKKLYPELEVILLT
AHGNIPDGVQAIKNGAFDYITKGDDNNKIIPLISRAMAQAKKNVGEKVKTEETQSFSFDAIKGKSEGMQQAVALARKVSA
TDVTVLLTGETGTGKEVFAQAIHRNSLRKENAFVAVNCSAFSKDLLESEIFGHKAGSFTGAMKDKKGLFEVADNGTIFLD
EIGEMAFELQAKLLRVLEAGEYIKIGDTKPTKVNVRVISATNRDLKKEIEQGNFREDLYYRLSVFQIHLPPLRERKEDIE
LLAESFIQLFSKKLGKQVEGMAPEFLKALKAADWRGNIRELRNVIERSMIVCDKQLTLQDLPIEIQNARQEDYSGKNYSE
FELAAMEKRHIAKVLQHTKGNKTEASRLLKIGLTTLYRKIEEYGI

Sequences:

>Translated_445_residues
MDSILIIDDEPQIRKLLSRMMELEGYEVFQAADCQSTLKQLKLHNPQVVLCDVFLPDGNGVDMVTTIKKLYPELEVILLT
AHGNIPDGVQAIKNGAFDYITKGDDNNKIIPLISRAMAQAKKNVGEKVKTEETQSFSFDAIKGKSEGMQQAVALARKVSA
TDVTVLLTGETGTGKEVFAQAIHRNSLRKENAFVAVNCSAFSKDLLESEIFGHKAGSFTGAMKDKKGLFEVADNGTIFLD
EIGEMAFELQAKLLRVLEAGEYIKIGDTKPTKVNVRVISATNRDLKKEIEQGNFREDLYYRLSVFQIHLPPLRERKEDIE
LLAESFIQLFSKKLGKQVEGMAPEFLKALKAADWRGNIRELRNVIERSMIVCDKQLTLQDLPIEIQNARQEDYSGKNYSE
FELAAMEKRHIAKVLQHTKGNKTEASRLLKIGLTTLYRKIEEYGI
>Mature_445_residues
MDSILIIDDEPQIRKLLSRMMELEGYEVFQAADCQSTLKQLKLHNPQVVLCDVFLPDGNGVDMVTTIKKLYPELEVILLT
AHGNIPDGVQAIKNGAFDYITKGDDNNKIIPLISRAMAQAKKNVGEKVKTEETQSFSFDAIKGKSEGMQQAVALARKVSA
TDVTVLLTGETGTGKEVFAQAIHRNSLRKENAFVAVNCSAFSKDLLESEIFGHKAGSFTGAMKDKKGLFEVADNGTIFLD
EIGEMAFELQAKLLRVLEAGEYIKIGDTKPTKVNVRVISATNRDLKKEIEQGNFREDLYYRLSVFQIHLPPLRERKEDIE
LLAESFIQLFSKKLGKQVEGMAPEFLKALKAADWRGNIRELRNVIERSMIVCDKQLTLQDLPIEIQNARQEDYSGKNYSE
FELAAMEKRHIAKVLQHTKGNKTEASRLLKIGLTTLYRKIEEYGI

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=454, Percent_Identity=39.2070484581498, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1790299, Length=466, Percent_Identity=36.0515021459227, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1790437, Length=438, Percent_Identity=38.5844748858447, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788905, Length=444, Percent_Identity=38.5135135135135, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1789233, Length=318, Percent_Identity=43.3962264150943, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789087, Length=311, Percent_Identity=43.4083601286174, Blast_Score=248, Evalue=6e-67,
Organism=Escherichia coli, GI87082117, Length=318, Percent_Identity=41.8238993710692, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=38.1538461538462, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1786524, Length=316, Percent_Identity=41.1392405063291, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI1787583, Length=347, Percent_Identity=34.8703170028818, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081872, Length=232, Percent_Identity=43.5344827586207, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081858, Length=314, Percent_Identity=31.5286624203822, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789828, Length=304, Percent_Identity=32.8947368421053, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1786599, Length=143, Percent_Identity=30.0699300699301, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786911, Length=102, Percent_Identity=32.3529411764706, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50005; Mature: 50005

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSILIIDDEPQIRKLLSRMMELEGYEVFQAADCQSTLKQLKLHNPQVVLCDVFLPDGNG
CCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
VDMVTTIKKLYPELEVILLTAHGNIPDGVQAIKNGAFDYITKGDDNNKIIPLISRAMAQA
CHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHH
KKNVGEKVKTEETQSFSFDAIKGKSEGMQQAVALARKVSATDVTVLLTGETGTGKEVFAQ
HHHHCHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
AIHRNSLRKENAFVAVNCSAFSKDLLESEIFGHKAGSFTGAMKDKKGLFEVADNGTIFLD
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEHH
EIGEMAFELQAKLLRVLEAGEYIKIGDTKPTKVNVRVISATNRDLKKEIEQGNFREDLYY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHE
RLSVFQIHLPPLRERKEDIELLAESFIQLFSKKLGKQVEGMAPEFLKALKAADWRGNIRE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCCCCHHH
LRNVIERSMIVCDKQLTLQDLPIEIQNARQEDYSGKNYSEFELAAMEKRHIAKVLQHTKG
HHHHHHHHHHHHCCCCCHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
NKTEASRLLKIGLTTLYRKIEEYGI
CHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSILIIDDEPQIRKLLSRMMELEGYEVFQAADCQSTLKQLKLHNPQVVLCDVFLPDGNG
CCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCC
VDMVTTIKKLYPELEVILLTAHGNIPDGVQAIKNGAFDYITKGDDNNKIIPLISRAMAQA
CHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHH
KKNVGEKVKTEETQSFSFDAIKGKSEGMQQAVALARKVSATDVTVLLTGETGTGKEVFAQ
HHHHCHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
AIHRNSLRKENAFVAVNCSAFSKDLLESEIFGHKAGSFTGAMKDKKGLFEVADNGTIFLD
HHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEHH
EIGEMAFELQAKLLRVLEAGEYIKIGDTKPTKVNVRVISATNRDLKKEIEQGNFREDLYY
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEEECCCHHHHHHHHCCCCHHHHHE
RLSVFQIHLPPLRERKEDIELLAESFIQLFSKKLGKQVEGMAPEFLKALKAADWRGNIRE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHCCCCCCHHH
LRNVIERSMIVCDKQLTLQDLPIEIQNARQEDYSGKNYSEFELAAMEKRHIAKVLQHTKG
HHHHHHHHHHHHCCCCCHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
NKTEASRLLKIGLTTLYRKIEEYGI
CHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]