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The map label for this gene is cirA [H]

Identifier: 150005622

GI number: 150005622

Start: 3933327

End: 3935504

Strand: Reverse

Name: cirA [H]

Synonym: BVU_3110

Alternate gene names: 150005622

Gene position: 3935504-3933327 (Counterclockwise)

Preceding gene: 150005624

Following gene: 150005620

Centisome position: 76.22

GC content: 40.59

Gene sequence:

>2178_bases
ATGAAAGTAAAGTTATTATTGACAGCAATTACTTTAAGCTGTCTGGCTATTGACGTACTGGCACAAGTCAGTATCAGTGG
AAAGATTGTGAGTGCCGATACCAACGAACCTATAGTGGGAGCTAATATCCGTATCGATCAAAGCCTTTCAGGATGCACCA
CAAATGGTAAAGGCGAGTTTTCCATCAGCAATCTCCCTGATGGGAAACACGTATTAAGAATCACGCATGTCAGTTACACA
CCCAAGTCTATCACGACAAAAGGAGGTGAAAAGAATCTTCTTATCAAGCTACAAGACAGTTTTACCAATATAGGCCAGGT
AGTAGTAACCGGTACAGGAACACACCACCGCATGACGGACAGTCCCGTGCCTGTTTCCGTTATCACTGCAAAGGATTTAA
GTAATGCCAGTGTAACATCGCTGGACGAGGCCTTACAAAAGCTGACCCCGTCTTTCTCAAGTATGACCAACGGCATGGGG
ACAACATTGAGTCTGAATGGATTGCCTGATGATTATTTCATTTTTCTGGAAAATGGCAAACGCCTGTATGGAGATGACAC
CTATGCTCGAATCAATGTTGCCAAAATCAAACGTATTGAAATATTGAACGGCGCTTCTTCCGCTCTTTACGGAACAAATG
CTATCGGAGGAGTTATCAACATCATTACTGATGATGCAAAAAATGCTATCAATGTTTCCAGCGATACCCGTTATGCCAGT
AAAGGACGTTTTACCCAGTCCGTAAACATAGATGTCAATACCGGCAAGTTCGGCTCCTACACCTCTTATCGCCGTCAGCA
GGCCGAAGGATGGCAACTGAATCCATACGAGGAGAACTCCAAAACTCATGAATTGGAAGAAACCGGGAAAGTAGCTTCTA
CAGGCTTCTATGCAAATACTGTCAATCAAAAATTCACTTTCGATGCTACCGACAAACTCTCTTTTTATGCCCGCGGCGGA
TATTATGACAACAAGACACGCCGCCCTTATGAAGCATACGACTACAACATATTGCATGAAACCTTTAATTATGGCATTGG
TGCCCAATACATGATAAATAAAGGGAATTATATTACCGCAGACTGTTACGCCGATCATTTTTCTTCCTCTTATTGTTTTT
TTAAAGACAATAAAACCTATAATGGAAAAGCAGGTGAAGAGCAAGTGCGCAAACGGACCCGTAATCACAATCTTAGCATA
AAAGGTATTTTTAAATTAGGTAACCGGCACAAACTTTCAGTCGGCACAGAATATATCGTTGATGTCTTGAAAAGTCAAAC
AGACAATATAGCCAAAGAAGATGCTTATACACTGGCCTTGTTTGCACAAGATGAAATAAAGTTACTGAGAAACCTACAGG
CTTTGATTGGTGTACGTTACATTTATCATGAAAATTTCAAAAATCATGCCACTCCCAATGTAGCACTGATGTATAAACCC
GGCAAATTCAATTTCCGTGCCTCCTATGCAGCAGGTTTCCGAACTCCTACCCTGTCTGAACTCTATGCCACTGACATAGC
TAAAAAAAATGACAGGTTGACAATAGGTAATTTGGATTTAAAGTCGGAAAAGAATAATTATTTCTCATTGAGTGCAGAGT
ATGTACATGAGCGTTTTTCAGTATCAGTCAATGCTTTTTATAATAATATTCGTGACATGATAGATTATAATACGATTGCC
ACGGGAGATAAAGCTATGGAGCAATATGGTCATAAGGAAGTTCGTCAACGTGATAATATAGCGGAGGCTAAAGTCCACGG
AATCAATGTATCCGCCAATGCATACCTAGGTGCCGGGTTCAATTTAAGCGGAGGATACACTCATCTTAATACCCAAGATG
TGGAATTGGAACAACCCATCGACAAAAGTATAAAAAACGCATACAATATCAATGCCCAATGGGCGCATTCATGGAAAATA
TATCGGTTGAATATAAATTTGAACGGCCGTATCAACAGCAAGCGTTTCTCTAAAAGTTACGGTTATGCTCCCGAGTATCA
ATTGTGGAATTTAAACACACGCCATTCTTTCAACTTAAAATCTGTAATCATCGAACCCGGATGCGGCATGGAAAACCTGT
TCGATTATATGGATGACCGTCCTTATAACAGCAATTATGCGACACTTACCCCCGGACGTTCATTCTACATCAGTCTGTCT
TTAAAATTTAAAAGCTAA

Upstream 100 bases:

>100_bases
GCTTTTCAGGGTGAAGCCAGGAAACCTGCCAAGTCCGAACATAGATAATCATGCTCTCCCGGGGTCAGGAAAGTGAATTA
TTAATTCTTAAATTCTTTCG

Downstream 100 bases:

>100_bases
AAAAATCAAAGACTTATCGAAGATAATATAAAATAAACCTCTATCTTTGCAACGGAATTAGTAATCGGGCTATCACATAG
CCCGATGCAAGGGAACCCGG

Product: putative iron transport-related exported protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MKVKLLLTAITLSCLAIDVLAQVSISGKIVSADTNEPIVGANIRIDQSLSGCTTNGKGEFSISNLPDGKHVLRITHVSYT
PKSITTKGGEKNLLIKLQDSFTNIGQVVVTGTGTHHRMTDSPVPVSVITAKDLSNASVTSLDEALQKLTPSFSSMTNGMG
TTLSLNGLPDDYFIFLENGKRLYGDDTYARINVAKIKRIEILNGASSALYGTNAIGGVINIITDDAKNAINVSSDTRYAS
KGRFTQSVNIDVNTGKFGSYTSYRRQQAEGWQLNPYEENSKTHELEETGKVASTGFYANTVNQKFTFDATDKLSFYARGG
YYDNKTRRPYEAYDYNILHETFNYGIGAQYMINKGNYITADCYADHFSSSYCFFKDNKTYNGKAGEEQVRKRTRNHNLSI
KGIFKLGNRHKLSVGTEYIVDVLKSQTDNIAKEDAYTLALFAQDEIKLLRNLQALIGVRYIYHENFKNHATPNVALMYKP
GKFNFRASYAAGFRTPTLSELYATDIAKKNDRLTIGNLDLKSEKNNYFSLSAEYVHERFSVSVNAFYNNIRDMIDYNTIA
TGDKAMEQYGHKEVRQRDNIAEAKVHGINVSANAYLGAGFNLSGGYTHLNTQDVELEQPIDKSIKNAYNINAQWAHSWKI
YRLNINLNGRINSKRFSKSYGYAPEYQLWNLNTRHSFNLKSVIIEPGCGMENLFDYMDDRPYNSNYATLTPGRSFYISLS
LKFKS

Sequences:

>Translated_725_residues
MKVKLLLTAITLSCLAIDVLAQVSISGKIVSADTNEPIVGANIRIDQSLSGCTTNGKGEFSISNLPDGKHVLRITHVSYT
PKSITTKGGEKNLLIKLQDSFTNIGQVVVTGTGTHHRMTDSPVPVSVITAKDLSNASVTSLDEALQKLTPSFSSMTNGMG
TTLSLNGLPDDYFIFLENGKRLYGDDTYARINVAKIKRIEILNGASSALYGTNAIGGVINIITDDAKNAINVSSDTRYAS
KGRFTQSVNIDVNTGKFGSYTSYRRQQAEGWQLNPYEENSKTHELEETGKVASTGFYANTVNQKFTFDATDKLSFYARGG
YYDNKTRRPYEAYDYNILHETFNYGIGAQYMINKGNYITADCYADHFSSSYCFFKDNKTYNGKAGEEQVRKRTRNHNLSI
KGIFKLGNRHKLSVGTEYIVDVLKSQTDNIAKEDAYTLALFAQDEIKLLRNLQALIGVRYIYHENFKNHATPNVALMYKP
GKFNFRASYAAGFRTPTLSELYATDIAKKNDRLTIGNLDLKSEKNNYFSLSAEYVHERFSVSVNAFYNNIRDMIDYNTIA
TGDKAMEQYGHKEVRQRDNIAEAKVHGINVSANAYLGAGFNLSGGYTHLNTQDVELEQPIDKSIKNAYNINAQWAHSWKI
YRLNINLNGRINSKRFSKSYGYAPEYQLWNLNTRHSFNLKSVIIEPGCGMENLFDYMDDRPYNSNYATLTPGRSFYISLS
LKFKS
>Mature_725_residues
MKVKLLLTAITLSCLAIDVLAQVSISGKIVSADTNEPIVGANIRIDQSLSGCTTNGKGEFSISNLPDGKHVLRITHVSYT
PKSITTKGGEKNLLIKLQDSFTNIGQVVVTGTGTHHRMTDSPVPVSVITAKDLSNASVTSLDEALQKLTPSFSSMTNGMG
TTLSLNGLPDDYFIFLENGKRLYGDDTYARINVAKIKRIEILNGASSALYGTNAIGGVINIITDDAKNAINVSSDTRYAS
KGRFTQSVNIDVNTGKFGSYTSYRRQQAEGWQLNPYEENSKTHELEETGKVASTGFYANTVNQKFTFDATDKLSFYARGG
YYDNKTRRPYEAYDYNILHETFNYGIGAQYMINKGNYITADCYADHFSSSYCFFKDNKTYNGKAGEEQVRKRTRNHNLSI
KGIFKLGNRHKLSVGTEYIVDVLKSQTDNIAKEDAYTLALFAQDEIKLLRNLQALIGVRYIYHENFKNHATPNVALMYKP
GKFNFRASYAAGFRTPTLSELYATDIAKKNDRLTIGNLDLKSEKNNYFSLSAEYVHERFSVSVNAFYNNIRDMIDYNTIA
TGDKAMEQYGHKEVRQRDNIAEAKVHGINVSANAYLGAGFNLSGGYTHLNTQDVELEQPIDKSIKNAYNINAQWAHSWKI
YRLNINLNGRINSKRFSKSYGYAPEYQLWNLNTRHSFNLKSVIIEPGCGMENLFDYMDDRPYNSNYATLTPGRSFYISLS
LKFKS

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=485, Percent_Identity=26.5979381443299, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1790405, Length=642, Percent_Identity=22.7414330218069, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81243; Mature: 81243

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKLLLTAITLSCLAIDVLAQVSISGKIVSADTNEPIVGANIRIDQSLSGCTTNGKGEF
CEEEEEEHHHHHHHHHHHHHHHEEECCEEEECCCCCCEEECEEEECCCCCCCCCCCCCCE
SISNLPDGKHVLRITHVSYTPKSITTKGGEKNLLIKLQDSFTNIGQVVVTGTGTHHRMTD
EECCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCC
SPVPVSVITAKDLSNASVTSLDEALQKLTPSFSSMTNGMGTTLSLNGLPDDYFIFLENGK
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCEEEEEECCC
RLYGDDTYARINVAKIKRIEILNGASSALYGTNAIGGVINIITDDAKNAINVSSDTRYAS
EEECCCCEEEEEEHHEEEEEEECCCCCCEECCCCCCCEEEEEECCCCCCEECCCCCCCCC
KGRFTQSVNIDVNTGKFGSYTSYRRQQAEGWQLNPYEENSKTHELEETGKVASTGFYANT
CCCEEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEECCEEEEC
VNQKFTFDATDKLSFYARGGYYDNKTRRPYEAYDYNILHETFNYGIGAQYMINKGNYITA
CCCEEEECCCCCEEEEECCCCCCCCCCCCCHHCCCCHHHHHHCCCCCCEEEEECCCEEEE
DCYADHFSSSYCFFKDNKTYNGKAGEEQVRKRTRNHNLSIKGIFKLGNRHKLSVGTEYIV
EEEHHCCCCCEEEEECCCEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHH
DVLKSQTDNIAKEDAYTLALFAQDEIKLLRNLQALIGVRYIYHENFKNHATPNVALMYKP
HHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEECC
GKFNFRASYAAGFRTPTLSELYATDIAKKNDRLTIGNLDLKSEKNNYFSLSAEYVHERFS
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECEEECCCCCCEEEEEHHHHHHHHE
VSVNAFYNNIRDMIDYNTIATGDKAMEQYGHKEVRQRDNIAEAKVHGINVSANAYLGAGF
EEHHHHHHHHHHHHCCCCCCCCHHHHHHHCHHHHHHHCCCCHHEEEEEEEECCEEEECCC
NLSGGYTHLNTQDVELEQPIDKSIKNAYNINAQWAHSWKIYRLNINLNGRINSKRFSKSY
CCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHCC
GYAPEYQLWNLNTRHSFNLKSVIIEPGCGMENLFDYMDDRPYNSNYATLTPGRSFYISLS
CCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCCEEEEEEE
LKFKS
EEECC
>Mature Secondary Structure
MKVKLLLTAITLSCLAIDVLAQVSISGKIVSADTNEPIVGANIRIDQSLSGCTTNGKGEF
CEEEEEEHHHHHHHHHHHHHHHEEECCEEEECCCCCCEEECEEEECCCCCCCCCCCCCCE
SISNLPDGKHVLRITHVSYTPKSITTKGGEKNLLIKLQDSFTNIGQVVVTGTGTHHRMTD
EECCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCC
SPVPVSVITAKDLSNASVTSLDEALQKLTPSFSSMTNGMGTTLSLNGLPDDYFIFLENGK
CCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCEEEEEECCC
RLYGDDTYARINVAKIKRIEILNGASSALYGTNAIGGVINIITDDAKNAINVSSDTRYAS
EEECCCCEEEEEEHHEEEEEEECCCCCCEECCCCCCCEEEEEECCCCCCEECCCCCCCCC
KGRFTQSVNIDVNTGKFGSYTSYRRQQAEGWQLNPYEENSKTHELEETGKVASTGFYANT
CCCEEEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCEEECCEEEEC
VNQKFTFDATDKLSFYARGGYYDNKTRRPYEAYDYNILHETFNYGIGAQYMINKGNYITA
CCCEEEECCCCCEEEEECCCCCCCCCCCCCHHCCCCHHHHHHCCCCCCEEEEECCCEEEE
DCYADHFSSSYCFFKDNKTYNGKAGEEQVRKRTRNHNLSIKGIFKLGNRHKLSVGTEYIV
EEEHHCCCCCEEEEECCCEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHH
DVLKSQTDNIAKEDAYTLALFAQDEIKLLRNLQALIGVRYIYHENFKNHATPNVALMYKP
HHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEECC
GKFNFRASYAAGFRTPTLSELYATDIAKKNDRLTIGNLDLKSEKNNYFSLSAEYVHERFS
CCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECEEECCCCCCEEEEEHHHHHHHHE
VSVNAFYNNIRDMIDYNTIATGDKAMEQYGHKEVRQRDNIAEAKVHGINVSANAYLGAGF
EEHHHHHHHHHHHHCCCCCCCCHHHHHHHCHHHHHHHCCCCHHEEEEEEEECCEEEECCC
NLSGGYTHLNTQDVELEQPIDKSIKNAYNINAQWAHSWKIYRLNINLNGRINSKRFSKSY
CCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHCC
GYAPEYQLWNLNTRHSFNLKSVIIEPGCGMENLFDYMDDRPYNSNYATLTPGRSFYISLS
CCCCCEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCCEEEEEEE
LKFKS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]